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| 1 | Different dietary starch sources alter the carcass traits, meat quality, and the profile of muscle amino acid and fatty acid in finishing pigs显示文摘Background: With increasing health awareness among consumers, the demand for healthier, tastier, higher quality and nutritional value pork is increasing. It has been shown that different dietary starch sources can alter the carcass traits and meat quality. However, research on the effects of different starch sources with clear different amylose/amylopectin ratio on the amino acid and fatty acid composition in Longissimus thoracis(L. thoracis) muscle of pigs is limited. This study aimed to investigate the effects of different dietary starch sources on carcass traits, meat quality, muscle amino acid and fatty acid composition, and the mRNA expression levels of genes involved in lipid metabolism and muscle fiber characteristics in finishing pigs. A total of 72 Duroc × Landrace × Large White barrows were randomly allocated to 3 different dietary treatment groups with 8 replicate pens/group and 3 pigs per pen.Tapioca starch(TS), corn starch(CS), and pea starch(PS), with amylose/amylopectin ratio of 0.11, 0.25, and 0.44,respectively, were used as their dietary starch sources for 40 days.Results: Results showed that the PS diet significantly increased(P < 0.05) the final body weight, average daily gain,loin-eye area, and fat-free lean index compared with the TS diet, but significantly decreased(P < 0.05) the feed to gain ratio and backfat thickness. Compared with the TS diet, PS diet also increased(P < 0.05) the pH45 min, marbling scores, the content of intramuscular fat and inosine monophosphate in the L. thoracis, and decreased(P < 0.05) the drip loss and shear force. In addition, compared with the TS diet, PS diet increased(P < 0.05) the proportions of flavor amino acids, DHA, EPA, and n-3 polyunsaturated fatty acid(PUFA) in the L. thoracis compared with TS diet,but decreased(P < 0.05) the ratio of n-6/n-3 PUFA. Furthermore, compared with the TS diet, PS diet also upregulated(P < 0.05) the lipogenic genes(FAS, LPL, SCD, ACCα) and myosin heavy-chain(MyHC)-IIa mRNA expression levels compared with the TS diet, but downregulated(P < 0.05) the CPT1 B and MyHC-IIb mRNA levels.Conclusions: In conclusion, these results provided compelling evidence that the different dietary starch source altered the carcass traits, meat flavor and quality in finishing pigs, and consumption of a diet with higher amylose/amylopectin ratio results in the production of a healthy, higher quality, and nutritional value pork. | Miao Yu Zhenming Li Ting Rong Gang Wang Zhichang Liu Weidong Chen Jiazhou Li Jianhao Li Xianyong Ma | 2021 | Journal of Animal Science and Biotechnology2021，12，1： | 13 |
| 2 | Planning and analysis of the demonstration project of the MVDC distribution network in Zhuhai显示文摘The DC distribution system is an important development direction of the distribution system,which can improve the reliability and the quality of the power supply,and support the new energy,the energy storage,the electric vehicles,and the flexible access of AC and DC loads to grid.To realize the demonstration application of the DC distribution technology,China's first demonstration project of the medium voltage DC distribution network will be built in Zhuhai,Guangdong Province to support the construction of the city energy internet.First,this paper analyzes the demand of the DC distribution network project,and puts forward the construction content and construction target.Then,it designs and analyzes the electrical connection mode,system operation mode,and startup and shutdown mode of the DC distribution network,and proposes the overall project construction plan.Finally,it conducts the specific project design and analysis,which mainly in elude the selection of equipment such as inverters,DC transformers and DC circuit breakers,the design and analysis of the DC control and protection system,the design and analysis of the overvoltage protection and the configuration scheme of the lightning arrester,and analysis of the system transient characteristics.The design and analysis of the engineering program is a combination of China's distribution network engineering practice and technical characteristics,which lays a solid foundation for the advancement of the DC power distribution technology in China,and has reference value and demonstration effect for the design and construction of other projects. | Lu QU Zhanqing YU Qiang SONG Zhichang YUAN Biao ZHAO Dawei YAO Jianfu CHEN Yao LIU Rong ZENG | 2019 | Frontiers in Energy2019，13，1： | 7 |
| 3 | Improving Nitrogen Use Efficiency in Rice through Enhancing Root Nitrate Uptake Mediated by a Nitrate Transporter, NRT1.1B显示文摘Nitrogen(N)is one of most important nutrients for crop production,which makes up 1%-5%of total plant dry matter(Marschner,2012).Due to the limited availability of N in soil,application of N fertilizers has been an important agronomic practice to increase crop yield.However,over-application of N fertilizers has caused pollution of N in soil,water and air. | ZhiChang Chen JianFeng Ma | 2015 | Journal of Genetics and Genomics2015，42，9： | 6 |
| 4 | Determination of the ^(12)C(p, γ)^(13)N reaction rates fromthe ^(12)C(~7Li,~6He)^(13)N reaction显示文摘The angular distribution of the 12C(7Li,6He)13N reaction at E(7Li) = 44.0 MeV was measured at the HI-13 tandem accelerator of Beijing, China. The asymptotic normalization coefficient (ANC) of 13N → 12C + p was derived to be (1.64 ± 0.11) fm-1/2 through the distorted wave Born approximation (DWBA) analysis. The ANC was then used to deduce the astrophysical S (E) factors and reaction rates for the 12C(p,γ)13N direct capture reaction at energies of astrophysical relevance. | LI ZhiHong, SU Jun, GUO Bing, LI ZhiChang, BAI XiXiang, LIU JianCheng, LI YunJu, YAN ShengQuan, WANG BaoXiang, WANG YouBao, LIAN Gang, ZENG Sheng, LI ErTao, CHEN YongShou, SHU NengChuan, FAN QiWen & LIU WeiPing China Institute of Atomic Energy, Beijing 102413, China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，4： | 6 |
| 5 | Predictive biomarkers for immune checkpoint blockade and opportunities for combination therapies显示文摘Immune checkpoint blockade therapies(ICBs)are a prominent breakthrough in cancer immunotherapy in recent years(named the 2013“Breakthrough of the Year”by the Science magazine).Thus far,FDA-approved ICBs primarily target immune checkpoints CTLA-4,PD-1,and PD-L1.Notwithstanding their impressive long-term therapeutic benefits,their efficacy is limited to a small subset of cancer patients.In addition,ICBs induce inadvertent immune-related adverse events(irAEs)and can be costly for long-term use.To overcome these limitations,two strategies are actively being pursued:identification of predictive biomarkers for clinical response to ICBs and multi-pronged combination therapies.Biomarkers will allow clinicians to practice a precision medicine approach in ICBs(biomarker-based patient selection)such as treating triple-negative breast cancer patients that exhibit PD-L1 staining of tumor-infiltrating immune cells in1%of the tumor area with nanoparticle albumin-bound(nab)epaclitaxel plus anti-PD-L1 and treating patients of MSI-H or MMR deficient unresectable or metastatic solid tumors with pembrolizumab(anti-PD-1).Importantly,the insights gained from these biomarker studies can guide rational combinatorial strategies such as CDK4/6 inhibitor/fractionated radiotherapy/HDACi in conjunction with ICBs to maximize therapeutic benefits.Further,with the rapid technological advents(e.g.,ATCT-Seq),we predict more reliable biomarkers will be identified,which in turn will inspire more promising combination therapies. | Hongxing Shen Eddy Shih-Hsin Yang Marty Conry John Fiveash Carlo Contreras James A.Bonner Lewis Zhichang Shi | 2019 | Genes & Diseases2019，6，3： | 5 |
| 6 | Isotopic Geochronological Evidence for the Caledonian Xiongdian Eclogite in the Northwestern Dabie Mountains,China显示文摘A typical HP/MT (high pressure/medium temperature) eclogite from Xiongdian, northwestern Dabie Mountains, has been geochronologically studied using the single-zircon U-Pb, 40Ar-39Ar and Sm-Nd methods. Prismatic zircons occurring as inclusions within garnets define a minimum crystallization age of 399.5±1.6 Ma. 40Ar-39Ar dating on amphibole gives a plateau age.of 399.2 ± 4 Ma, which is interpreted as a retrogression age of amphibolite facies. This integrated study enables us to conclude that the age of high-pressure metamorphism is older than 399.5 ± 1.6 Ma, suggesting Caledonian collision between the North China and Yangtze plates. Round zircon within the aggregate of quartz and muscovite gives a concordant age of 301± 2 Ma, reflecting a later retrogression event. An age profile of post-eclogite metamorphism is documented, including amphibolite facies metamorphism at 399.2 Ma shortly after eclogitization and later retrogressive metamorphism at 301 Ma. Sm-Nd mineral isochron of garnet+omphacite | Jian PingYichang Institute of Geology and Mineral Resources. CAGS, Yichang City,Hubei Province 443003Yang Weiran China University of Geosciences, Wuhan, HubeiLi Zhichang Yichang Institute of Geology and Mineral Resources, CAGS, Yichang, HubeiZhou Huifang Tianjin Instutite of Geology and Mineral Resources, CAGS, Tianjin Zhu Xiling | 1997 | Acta Geologica Sinica(English Edition)1997，71，4： | 4 |
| 7 | Neutron halo state of ^(13)C显示文摘Angular distributions for the 12C(d, p)13C transfer reactions have been measured at Ed = 11.8 MeV, and compared with those of the DWBA calculations. By means of this comparison, density distributions of the last neutron in the ground state and the first 1/2+ state of 13C are extracted. The properties of these states in 13C have also been studied in the framework of the nonlinear relativistic mean-field theory with NL-SH parameters. It is found that the first l/2+ state in 13C is a neutron halo state shown by both the experimental and theoretical density distributions of the last neutron. | LIU Zuhua, LIN Chengjian, LI Zhichang, ZHANG Huanqiao, CHEN Baoqiu, MA Zhongyu, WU Yuewei, LIU Jiancheng & LI ShuyuanChina Institute of Atomic Energy, Beijing 102413, China | 2001 | Chinese Science Bulletin2001，46，1： | 3 |
| 8 | Fiber-shaped organic electrochemical transistors for biochemical detections with high sensitivity and stability显示文摘Precise and continuous monitoring of biochemicals by biosensors assists to understand physiological functions for various diagnostics and therapeutic applications.For implanted biosensors,small size and flexibility are essential for minimizing tissue damage and achieving accurate detection.However,the active surface area of sensor decreases as the sensor becomes smaller,which will increase the impedance and decrease the signal to noise ratio,resulting in a poor detection limit.Taking advantages of local amplification effect,organic electrochemical transistors(OECTs)constitute promising candidates for high-sensitive monitoring.However,their detections in deep tissues are rarely reported.Herein,we report a family of implantable,fiber-shaped all-in-one OECTs based on carbon nanotube fibers for versatile biochemical detection including H2O2,glucose,dopamine and glutamate.These fiber-shaped OECTs demonstrated high sensitivity,dynamical stability in physiological environment and antiinterference capability.After implantation in mouse brain,7-day dopamine monitoring in vivo was realized for the first time.These fiber-shaped OECTs could be great additions to the'life science'tool box and represent promising avenue for biomedical monitoring. | Xiaoying Wu Jianyou Feng Jue Deng Zhichang Cui Liyuan Wang Songlin Xie Chuanrui Chen Chengqiang Tang Zhengqi Han Hongbo Yu Xuemei Sun Huisheng Peng | 2020 | Science China Chemistry2020，63，9： | 3 |
| 9 | Interaction Time Study of the Dissipative Process in the Reaction ^(19)F+^(45)Sc显示文摘Excitation functions have been measured for the dissipative products of 4≤Z≤12 in ^(19)F+^(45)Sc reaction from 102 to ^(108)MeV by a step of 300keV at θl=42°.The energy coherence widths have been extracted and the dinuclear system lifetimes of the order of 10^(-21 ) s have been deduced by analysing the cross section Auctuations. | WANG Qi LI Songlin LU Jun XU Hushan YIN Xu FAN Enjie GUO Zhongyan ZHU Yongtai XIE Yuanxiang LI Zhichang LU Xiuqin HU Xiaoqing | 1993 | Chinese Physics Letters1993，10，11： | 3 |
| 10 | Creating burdock polysaccharide-oleanolic acid-ursolic acid nanoparticles to deliver enhanced anti-inflammatory effects:fabrication,structural characterization and property evaluation显示文摘This study explored the potential of polysaccharides from Actium lappa(ALPs)as natural wall materials for producing ALP-based nanoparticles to deliver poorly water-soluble oleanolic acid(OA)and ursolic acid(UA).Encapsulating OA+UA with ALPs(ALP:OA+UA,50:1;OA:UA,1:1)changed the crystalline nature to a more amorphous state through hydrogen bonding and involving O-H/C-O/O-C-O groups.ALP-OA/UA nanoparticles had a particle size and zeta potential(in water)of 199.1 nm/-7.15 mV,with a narrow unimodal size distribution,and excellent pH,salt solution,temperature and storage stability.Compared with ALPs,ALPOA/UA nanoparticles showed enhanced anti-inflammatory activity(especially at a dose of 100μg/mL)in a CuSO-induced zebrafish inflammation model via down-regulating the NF-κB signalling pathway and gene expression of associated transcription factors and cytokines(TNF-α,IL-1βand IL-8).Therefore,ALP-based nanoparticles are natural and anti-inflammatory carriers for hydrophobic bioactive molecules. | Shanshan Zhu Zhichang Qiu Xuguang Qiao Geoffrey I.N.Waterhouse Wenqing Zhu Wenting Zhao Qiuxia He Zhenjia Zheng | 2023 | Food Science and Human Wellness2023，12，2： | 2 |
| 11 | Characteristics and generation mechanism of turbidity maximum in the Changjiang Estuary显示文摘Sediment convergence and resuspension are the two major mechanisms in forming turbidity maximum (TM) in the Changjiang Estuary. Sediment convergence is mainly controlled by the interaction between runoff and tidal current, the mixing of freshwater and salt water, the former forming tidal TM, whereas the latter forming brackish TM. The TM in the Changjiang Estuary is characterized by a combination of tidal TM and brackish TM, which varies temporally and spatially. | Pan Ding’an Shen Huanting Mao Zhichang and Liu Xincheng (1. State Key Lab of Estuarine and Coastal Research, East China Normal University, Shanghai 200062, China) | 2000 | Acta Oceanologica Sinica2000，19，1： | 2 |
| 12 | Effect of the Structure of Cations and Anions of Ionic Liquids on Separation of Aromatics from Hydrocarbon Mixtures显示文摘The effects of the structure of typical cations and anions of ionic liquids on the separation of benzene and toluene from aromatic/paraffin mixtures were studied. The results showed that the corresponding separation factors were considerably larger than those of the traditional solvents (Benzene+Hexane+sulfolane), and that the ionic liquids could be used as novel solvents for the separation of aromatics from hydrocarbon mixtures. The key parameters governing the ability of ionic liquids for separating aromatics from hydrocarbon sources were investigated. It was found that the effectiveness of the ionic liquids, based on the same anion, changed in the cation order of [BIqu]+< [BPy]+< [BMIM]+. The selectivity of the ionic liquid toward aromatics decreased apparently with the increasing length of the substituted alkyl chain of its cationic head ring. The separation factors, based on the same cation, changed in the anion order of [Tf2N]-<[PF6]-<[BF4]-<[C2H5SO4]-. The solubilities of the aromatics were greater in the ionic liquids based on the former three anions than that in the ionic liquids involving [C2H5SO4]-. | Liu Yansheng Zhang Zhongxin Zhang Guofu Liu Zhichang Hu Yufeng Shi Quan Ji Dejun | 2006 | Petroleum Science2006，3，3： | 2 |
| 13 | Experimental results for the vapor-liquid equilibria of 0(formaldehyde+1,3,5-trioxane+methanol+salt+water)systems and comparison with predictions显示文摘The salt effect on the vaporliquid phase equilibrium(VLE)of solvent mixtures is of significant interest in the industrial production of 1,3,5trioxane.Experimental data for the VLE of quinary systems(formaldehyde+1,3,5trioxane+methanol+salt+water)and their ternary subsystems(formaldehyde+salt+water),(1,3,5trioxane+salt+water),and(methanol+salt+water)were systematic measured under atmospheric pressure.The salts considered included KBr,NaNO_(3),and CaCl_(2).The extended UNIFAC model was used to describe the VLE of the saltcontaining reactive mixtures.The model parameters were determined from the experimental VLE data of ternary systems or obtained from the literature,and then were used to predict the VLE of systems(1,3,5trioxane+KBr+water),(methanol+KBr+water),(formaldehyde+KBr+water),and(formaldehyde+1,3,5trioxane+methanol+salt+water)with salt=KBr,NaNO_(3),and CaCl_(2).The predicted results showed good agreements with the measured results.Furthermore,the model was used to uncover the salt effect on the VLE of these multisolvent reactive systems. | Xianming Zhang Mengchen Li Yufeng Hu Zhichang Liu Shuqin Mo | 2021 | Chinese Journal of Chemical Engineering2021，34，4： | 2 |
| 14 | Beijing Q3D Magnetic Spectrometer and Its Applications 显示文摘 | Cheng Yehao Yah Chen | 1993 | Nucl Instrum Methods1993，336，： | 1 |
| 15 | Effects of a natu-rally occurring mutation in the Hepatitis B virus basal core promoter on precore gene expression and viral replication显示文摘 | Xu zhichang Chen Min | 1996 | J Virol1996，10，9： | 1 |
| 16 | Spherical fuel element for 10MW HTGR显示文摘 | Xu Shijiang Xu Zhichang etal | 1994 | J of Tsinghua University(Science and Technology)1994，34，2： | 1 |
| 17 | Adaptive Perona Malik Model Based on the Variable Exponent for Image Denoising显示文摘 | Zhichang Guo Jiebao Sun Dazhi Zhang Boying Wu | 2012 | Image Processing IEEE Transactions on2012，21，3： | 1 |
| 18 | Complexity Science,Systems Thinking and Pragmatic Sensibility显示文摘 | Zhichang Zhu | 2007 | Systems Research and Behavioral Science2007，，24： | 1 |
| 19 | Preparation of pitch-based spherical activated car-bon with developed mesopore by the aid of ferrocene显示文摘 | Zhichang Liu Licheng ling | 1999 | Carbon1999，37，： | 1 |
| 20 | Effect of hydrogen on the mesopore development of pitchbased spherical activated carbon containing iron during activation by steam显示文摘 | Zhichang Liu Licheng Ling Wenming Qiao | 1999 | Carbon1999，37，： | 1 |
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