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| 1 | Ascorbate antagonizes nickel ion to regulate JMJD1A expression in kidney cancer cells显示文摘histone demethylase Jumonji 包含域的蛋白质 1A (JMJD1A ) 的反常表示与许多种癌症被联系。JMJD1A 也是 hypoxic 反应基因,它的表示被组织缺氧可诱导的 factor-1 (HIF-1 ) 调整。在这研究,我们在开发和组织缺氧小径决定了 JMJD1A 的角色。我们也测量了 JMJD1A 和二组织缺氧因素葡萄糖 transporter 的表示 1 ( GLUT1 )并且在 786-0 和 HEK293 细胞的脉管的 endothelial 生长因素( VEGF )为 24 h 与 NiCl2 ( 2.5100 M )的不同集中对待,并且发现 JMJD1A mRNA 和蛋白质与 NiCl2 的增加的集中是起来调整的。我们然后观察到 ascorbate 能延迟以通过减少的一种剂量依赖者方式的导致 NiCl2 的 JMJD1A 表示的起来调整的效果 HIF-1 的稳定性蛋白质。Immunohistochemical 分析进一步证明 ascorbate 在 786-0, HEK293,和 OS-RC-2 房间反对了 JMJD1A 表示的导致 Ni2+ 的起来规定。这些调查结果建议 Ni2+ 和 ascorbate 能调整 histone demethylase JMJD1A 的表示,它为癌症开发或抑制是重要的。 | Xiaoqiang Guo Jingxiao Lu Yuejia Wang Yaoting Gui Xianglin Duan Zhiming Cai | 2012 | Acta Biochimica et Biophysica Sinica2012，44，4： | 5 |
| 2 | Regulation of histone demethylase KDM6B by hypoxia-inducible factor-2α显示文摘离氨酸(K) 特定的 demethylase 6B (KDM6B ) 是 histone H3K27 demethylase,它明确地催化 H3 lysine-27 tri/dimethylation (H3K27me3/2 ) 的 demethylation。KDM6B 能由支持与 RNA 聚合酶 II 和相关延伸因素被联系的 transcriptional 延伸激活基因抄写。KDM6B 因此为基因表示的规定是重要的。以前的研究显示了象 KDM3A, KDM4B,和 KDM4C 那样的几 histone demethylases 被组织缺氧可诱导的因素(HIF ) 调整。但是, KDM6B 上的组织缺氧的效果充分没被理解。在这研究,我们发现 KDM6B mRNA 和蛋白质的表示层次在组织缺氧下面是平常地起来调整的(1% O 2) 或模仿组织缺氧(desferrioxamine mesylate 或 CoCl 2 处理)(P < 0.05 ) 。RNAi 的结果证明 KDM6B 的起来规定依赖于 HIF-2,然而并非在 HIF-1 上。染色质 immunoprecipitation 试金的结果显示在 KDM6B 倡导者(4041 ~ 4037 ) 有一个组织缺氧反应元素。Co-IP 试金的结果显示 KDM6B 能与 HIF-2 或 HIF-1 形成建筑群。击倒的实验暗示 KDM6B 是为 HIF-2 目标基因的一个潜在的管理者。这些数据证明 KDM6B 是 HIF-2 调整的新组织缺氧反应基因。我们的结果也证明 KDM6B 是 HIF- 的潜在的激活剂,它为组织缺氧反应基因的激活是重要的。 | Xiaoqiang Guo Zha ntao Tian Xuliang Wang Shuhong Pan Weiren Huang Yongqing Shen Yaoting Gui Xianglin Duan Zhiming Cai | 2015 | Acta Biochimica et Biophysica Sinica2015，47，2： | 5 |
| 3 | Highly effective H_(2)/D_(2)separation in a stable Cu-based metalorganic framework显示文摘A three-dimensional copper metal-organic framework with the rare chabazite(CHA)topology namely FJI-Y11 has been constructed with flexibly carboxylic ligand 5,5'-[(1,4-phenylenebis(methylene))bis(oxy)]diisophthalic acid(H_(4)L).FJI-Y11 exhibits high water stability with the pH range from 2 to 12 at temperature as high as 373 K.Importantly,FJI-Y11 also shows high efficiency of hydrogen isotope separation using dynamic column breakthrough experiments under atmospheric pressure at 77 K.Attributed to its excellent structural stability,FJI-Y11 possesses good regenerated performance and maintains high separation efficiency after three cycles of breakthrough experiments. | Yanan Si Xiang He Jie Jiang Zhiming Duan Wenjing Wang Daqiang Yuan | 2021 | Nano Research2021，14，2： | 3 |
| 4 | Shale high pressure isothermal adsorption curve and the production dynamic experiments of gas well显示文摘The high pressure static adsorption curves of shale samples from Silurian Changning-Weiyuan Longmaxi Formation were tested by using high pressure isothermal adsorption equipment.The physical modeling of depletion production was tested on single cores and multi-core series by using self-developed shale gas fluid-solid coupling experiment system.The adsorption and desorption laws were summarized and a high pressure isothermal adsorption model was established.The calculation formula of gas content was corrected,and the producing law of adsorption gas was determined.The study results show that the isothermal adsorption law of the shale reservoir under high pressure was different from the conventional low pressure.The high pressure isothermal adsorption curve had the maximum value in excess adsorption with pressure change,and the corresponding pressure was the critical desorption pressure.The high pressure isothermal curve can be used to evaluate the amount of adsorbed gas and the producing degree of adsorption gas.The high pressure isothermal adsorption model can fit and characterize the high pressure isothermal adsorption law of shale.The modified gas content calculation method can evaluate the gas content and the proportion of adsorbed gas more objectively,and is the theoretical basis of reserve assessment and production decline analysis.The producing degree of adsorption gas is closely related to the pressure,only when the reservoir pressure is lower than the critical desorption pressure,the adsorption gas can be produced effectively.In the process of gas well production,the pressure drop in the near-well area is large,the production of adsorption gas is high;away from the wellbore,the adsorption gas is low in production,or no production. | DUAN Xianggang HU Zhiming GAO Shusheng SHEN Rui LIU Huaxun CHANG Jin WANG Lin | 2018 | Petroleum Exploration and Development2018，45，1： | 1 |
| 5 | n-Channel Organic Transistors Processed from Halogen-Free Solvents: Solvent Effect on Thin-Film Morphology and Charge Transport显示文摘非使氯化的溶剂为由于他们的环境地友好的特征的器官的电子处理高度更好。四不同没有卤素的溶剂, tetrafuran,甲苯,元二甲苯和 1,2,4-trimethylbenzene,被选择制作 n 隧道基于 3-hexylundecyl,代替的萘 diimides 熔化了与的器官的薄电影晶体管(OTFT )(1,3-dithiol-2-ylidene ) malononitrile 组(NDI3HU-DTYM2 ) 。OTFT 在周围的状况下面基于 NDI3HU-DTYM2 显示出多达 1.37 厘米 2·V−1·s−1 的电子活动性。这在为从没有卤素的溶剂处理的 n 隧道 OTFT 的最高的设备表演之中。不同薄电影的形态学,从无特色的低水晶的形态学到排列得好的 nanofibres,在设备表演上有大效果。这些结果可能为器官的电子设备阐明溶剂选择和产生解决方案进程。 | Simin Gao Yonghui Hu Zhiming Duan Xike Gao | 2016 | Chinese Journal of Chemistry2016，34，7： | 1 |
| 6 | Selective catalytic reduction of NO_x by hydrogen over modified Pd/TiO_2-Al_2O_3 catalyst under lean-burn conditions显示文摘A series of Ni,Sn and Ca modified Pd/TiO2-Al2O3catalysts were prepared by the incipient wetness impregnation method and their catalytic performance for the selective catalytic reduction of NOxby H2was evaluated.The results showed that the NOxconversion and N2selectivity were improved over Pd-Sn/TiO2-Al2O3and Pd-Ni/TiO2-Al2O3catalysts above 200°C.More importantly,the N2selectivity and high-temperature activity of Pd-Sn/TiO2-Al2O3catalyst was far superior to the single Pd/TiO2-Al2O3catalyst.The optimal Sn loading was 2 wt.%.X-ray diffraction(XRD)results showed that the interaction between Pd and Sn promotes the dispersion of Pd over TiO2-Al2O3.Temperature-programmed reduction(H2-TPR)results demonstrated that the addition of Sn contributes to the formation of Pd0and improving the redox property of Pd/TiO2-Al2O3.The additives of Ni and Sn also facilitated the absorption of NOxand the oxidation of NO to NO2,which play important roles in the selective catalytic reduction of NOxby hydrogen. | Kaijiao Duan Zhiming Liu Lei Yuan | 2014 | Chinese Science Bulletin2014，59，31： | 1 |
| 7 | Control Effect and Cost Evaluation of Different Sex Pheromones and Trapping Lamps against Spodoptern litura,Helicoverpa assulta and Helicoverpa armigera in Tobacco显示文摘[Objective]The aim was to study the control effect of different sex pheromones and trapping lamps against main pests in tobacco. [Method]Control effect of sex pheromone of different matrix lures and Jiaduo trapping lamp against Spodoptern litura,Helicoverpa assulta and Helicoverpa armigera in tobacco in Tengchong of Yunnan were determined and compared,and the control cost was evaluated. [Result] The use of insect sex pheromones and insecticidal light traps had certain effect against S. litura and H. armiger. The trapping effect of sex pheromone traps was better than that of Jiaduo trapping lamp,and the PVC matrix lure had better performance than rubber matrix lure,which had strongest capturing capacity,continuous control effect and significant effort against S. litura. The traps with different settled densities and hanging heights also had different trapping effect against S. litura and H. armiger,and the hanging height of 100 - 150 cm from ground was the best; as the cost was considered,the cost of the area with low density of traps was the lowest,which was reduced by over 44% than conventional chemical control area. [Conclusion]It is safe and effective to use sex pheromone and insecticidal light traps to control S. litura and H. armigera,and it is a green environmental protection biological physical control technology,having extended application prospect in large area. | Yongliang LI Li LI Zhiming HU Xingdong YANG Yanping DUAN Jinguang YANG | 2012 | Plant Diseases and Pests2012，3，3： | 1 |
| 8 | Novel Pd-Au/TiO2 catalyst for the selective eatalytie reduction of NO~ by Hz 显示文摘 | Kaijiao Duan Zhiming Liu | 2014 | Catalysis Communications2014，，57： | 1 |
| 9 | The effect of preparation conditions of Pt/Al2O3 on its catalytic performance for the H2-SCR in the presence of oxygen显示文摘 | Lei YUAN Xiang ZHENG Kaijiao DUAN Hao HU Jinggang WANG Seong Ihl WOO Zhiming LIU | 2013 | Frontiers of Environmental Science & Engineering2013，7，3： | 1 |
| 10 | High-mobility Group Box 1 is Associated with Clinicopathologic Features in Patients with Hepatocellular Carcinoma显示文摘 | Wei Jiang Zhiming Wang Xinying Li Xuegong Fan Yankun Duan | 2012 | Pathology & Oncology Research2012，，： | 1 |
| 11 | Characteristics of Falls Among Older People-China,2018显示文摘What is already known about this topic?The incidence of falls among older people is 20.7%in China.Falls are the top cause for death from injuries in people aged 65 years and above,and mortality rates increase with age in China.There are few reports on the epidemiological characteristics of falls in older people nationwide in recent years.What is added by this report?This study found that among older people with falls reported in the National Injury Surveillance System(NISS)in 2018,there were more females than males.The peak time for falls was in the morning.Home was the most common site where falls occurred,and leisure activities and housework were the main activities when falls occurred.After falling,the lower limbs and head were most often injured with bruises and fractures.The degree of injury was mainly mild and moderate.What are the implications for public health practice?Data based on the NISS can be used as an additional data source for research on falls in China.This study identified priorities for the control and prevention of falls. | Zhiming Lu Pengpeng Ye Yuan Wang Leilei Duan Yuliang Er | 2021 | China CDC weekly2021，3，4： | 0 |
| 12 | Effects of UV Light Illumination on Track Etching in Polycarbonate显示文摘Nuclear track membranes offer distinct advantages over conventional membranes due to their precisely determined structure . The pore size, shape and density can be controlled intentionally so that a membrane with the required characteristics can be produced. The track etching technology plays a most important role in the production of nuclear track membranes. In this work, the pretreatment effects by using UV light illumination on track etching of polycarbonate (PC) track membranes were investigated. | Duan Jinglai, Liu Jie, Wang Zhiguang, Hou Mingdong, Jin Yunfan, Sun Youmei Song Yin, Yao Huijun, Zhao Zhiming and Yao Cunfeng | 2004 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2004，，1： | 0 |
| 13 | A Case Report on Application of Multimodal Imaging to an Alcoholic Cardiomyopathic Patient Undergoing Heart Transplantation显示文摘Alcoholic cardiomyopathy(ACM)is a dilated cardiomyopathy induced by excessive alcohol consumption that causes progressive cardiac dysfunction and chamber dilatation,leading to arrhythmias,heart failure,and death.Cardiac transplantation is the final measure for end-stage ACM.In this case,we used multimodal imaging for ACM diagnosis in a patient with refractory heart failure.The patient received a heart transplant with a good prognosis,and his pathological results after the transplant confirmed our suspected diagnosis.End-stage ACM may lead to refractory heart failure and multimodal imaging may play an important role in the diagnosis,prognosis prediction,and follow-up study of suspected ACM. | Zhiming Li Yu Wang Bingsong Duan Dan Han Wei Chen | 2022 | Cardiology Discovery2022，2，3： | 0 |
| 14 | Tunable quantum anomalous Hall effects in ferromagnetic van der Waals heterostructures显示文摘The quantum anomalous Hall effect(QAHE)has unique advantages in topotronic applications,but it is still challenging to realize the QAHE with tunable magnetic and topological properties for building functional devices.Through systematic first-principles calculations,we predict that the in-plane magnetization induced QAHE with Chern numbers C=±1 and the out-of-plane magnetization induced QAHE with high Chern numbers C=±3 can be realized in a single material candidate,which is composed of van der Waals(vdW)coupled Bi and MnBi2 Te4 monolayers.The switching between different phases of QAHE can be controlled in multiple ways,such as applying strain or(weak)magnetic field or twisting the vdW materials.The prediction of an experimentally available material system hosting robust,highly tunable QAHE will stimulate great research interest in the field.Our work opens a new avenue for the realization of tunable QAHE and provides a practical material platform for the development of topological electronics. | Feng Xue Yusheng Hou Zhe Wang Zhiming Xu Ke He Ruqian Wu Yong Xu Wenhui Duan | 2024 | National Science Review2024，11，3： | 0 |
| 15 | XRD Investigation of Phase Change in N-doped Diamond after High Energy Heavy Ion Irradiations显示文摘We have proposed a novel technique, 'low energy ion implantation+swift heavy ion irradiation', for synthesizing new structures in atom mixed materials. The schematic procedure of this technique is shown in Fig.1. In detail, the original samples were prepared at first (1), and then they were implanted at room temperature (RT) with keV ions (2) after that irradiated at RT with high-energy heavy ions (3). After high-energy | Wang Zhiguang, Zhao Zhiming, Song Yin, Jin Yunfan, Liu Jie, Sun Youmei Zhang Chonghong and Duan Jinglai | 2002 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2002，，1： | 0 |
| 16 | Effectiveness of Group-Based Interventions for Fall Prevention Among Community-Dwelling Older Adults—7 Regions,6 PLADs,China,2019–2020显示文摘Summary What is already known about this topic?Many of the current studies focusing on fall prevention interventions have been conducted in hospital settings within a select few urban areas in China,thus yielding limited evidence on the effectiveness of large-scale,multicenter,community-based interventions. | Yuliang Er Zhiming Lu Ye Jin Pengpeng Ye Leilei Duan | 2023 | China CDC weekly2023，5，47： | 0 |
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