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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease显示文摘 | Tang B Xiong H Sun P Zhang Y Wang D Hu Z Zhu Z Ma H Pan Q Xia JH Xia K Zhang Z | 2006 | 中国生物学文摘2006，20，8： | 30 |
| 3 | m^6A mRNA methylation sustains Treg suppressive functions显示文摘 | Jiyu Tong Guangchao Cao Ting Zhang Esen Sefik Maria Carolina Amezcua Vesely James P Broughton Shu Zhu Huabin Li Bin Li Lei Chen Howard Y Chang Bing Su Richard A Flavell Hua-Bing Li | 2018 | Cell Research2018，28，2： | 30 |
| 4 | Association of N-terminal pro-brain natriuretic peptide with the severity of coronary artery disease in patients with normal left ventricular ejection fraction显示文摘 | Wu NQ Guo YL Li XL Liu J Qing P Xu RX Zhu CG Jia Y J Liu G Dong Q Jiang LX Li J J Ma FL | 2014 | Chinese Medical Journal2014，，4： | 23 |
| 5 | The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters显示文摘最近的研究在众多的生物过程增加了我们长 noncoding RNA (lncRNAs ) 的理解,但是很少在体的房间 reprogramming 检验了他们的角色。通过表示介绍并且功能的屏蔽,我们鉴别了大 intergenic noncoding RNA p21 (lincRNA-p21 ) 损害 reprogramming。尤其是, lincRNA-p21 被 p53 导致,但是不在 reprogramming 支持 apoptosis 或房间老朽。相反, lincRNA-p21 与 H3K9 methyltransferase SETDB1 和维护 DNA methyltransferase DNMT1 联系,它被 RNA 有约束力的蛋白质 HNRNPK 便于。因而, lincRNA-p21 由在 pluripotency 基因倡导者支撑 H3K9me3 或 CpG methylation 阻止 reprogramming。我们的结果在 reprogramming 提供卓见进 lncRNAs 的角色并且建立在 p53 和 heterochromatin 规定之间的一个新奇连接。 | Xichen Bao Haitao Wu Xihua Zhu Xiangpeng Guo Andrew P Hutchins Zhiwei Luo Hong Song Yongqiang Chen Keyu Lai Menghui Yin Lingxiao Xu Liang Zhou Jiekai Chen Dongye Wang Baoming Qin Jon Frampton Hung-Fat Tse Duanqing Pei Huating Wang Biliang Zhang Miguel A Esteban | 2015 | Cell Research2015，25，1： | 21 |
| 6 | Proton accumulation accelerated by heavy chemical nitrogen fertilization and its long-term impact on acidifying rate in a typical arable soil in the Huang-Huai-Hai Plain显示文摘Cropland productivity has been significantly impacted by soil acidification resulted from nitrogen(N) fertilization, especially as a result of excess ammoniacal N input. With decades' intensive agricultural cultivation and heavy chemical N input in the Huang-Huai-Hai Plain, the impact extent of induced proton input on soil p H in the long term was not yet clear. In this study, acidification rates of different soil layers in the soil profile(0–120 cm) were calculated by p H buffer capacity(p HBC) and net input of protons due to chemical N incorporation. Topsoil(0–20 cm) p H changes of a long-term fertilization field(from 1989) were determined to validate the predicted values. The results showed that the acid and alkali buffer capacities varied significantly in the soil profile, averaged 692 and 39.8 mmolc kg–1 p H–1, respectively. A significant(P<0.05) correlation was found between p HBC and the content of calcium carbonate. Based on the commonly used application rate of urea(500 kg N ha–1 yr–1), the induced proton input in this region was predicted to be 16.1 kmol ha–1 yr–1, and nitrification and plant uptake of nitrate were the most important mechanisms for proton producing and consuming, respectively. The acidification rate of topsoil(0–20 cm) was estimated to be 0.01 unit p H yr–1 at the assumed N fertilization level. From 1989 to 2009, topsoil p H(0–20 cm) of the long-term fertilization field decreased from 8.65 to 8.50 for the PK(phosphorus, 150 kg P2O5 ha–1 yr–1; potassium, 300 kg K2 O ha–1 yr–1; without N fertilization), and 8.30 for NPK(nitrogen, 300 kg N ha–1 yr–1; phosphorus, 150 kg P2O5 ha–1 yr–1; potassium, 300 kg K2 O ha–1 yr–1), respectively. Therefore, the apparent soil acidification rate induced by N fertilization equaled to 0.01 unit p H yr–1, which can be a reference to the estimated result, considering the effect of atmospheric N deposition, crop biomass, field management and plant uptake of other nutrients and cations. As protons could be consumed by some field practices, such as stubble return and coupled water and nutrient management, soil p H would maintain relatively stable if proper management practices can be adopted in this region. | HUANG P ing ZHANG Jia-bao XIN Xiu-li ZHU An-ning ZHANG Cong-zhi MA Dong-hao ZHU Qiang-gen YANG Shan WU Sheng-jun | 2015 | Journal of Integrative Agriculture2015，14，1： | 18 |
| 7 | Experimental investigation on breaching of embankments显示文摘Breaching of embankments has recently drawn more and more attention due to its importance in the development of early warning systems for embankment failures,in the evacuation plans of people at risk,in the design method of embankments based on a risk-approach,etc. The erosion process observed during embankment breaching tests in the laboratory and the analysis of the results are described in this paper. Five embankments,one constructed with pure sand,four with different sand-silt-clay mixtures were tested. The height of the embankments was 75 cm and the width at the crest was 60 cm. Examination of the data from these tests indicated that headcut erosion played an important role in the process of breach growth in the embankments made of cohesive soil mixtures. Flow shear erosion,fluidization of the headcut slope surface,undermining of the headcut due to impinging jet scour and discrete soil mechanical slope mass failure from the headcut were all observed during these tests. For the embankment constructed with pure sand,the breach erosion process was dominated by shear erosion,which led to a gradual and relatively uniform retreat of the downstream slope. The cohesive proportion in the sand-silt-clay mixtures strongly slowed down the erosion process. | ZHU YongHui VISSER P J VRIJLING J K WANG GuangQian | 2011 | Science China(Technological Sciences)2011，54，1： | 17 |
| 8 | Protective actions of salvianolic acid A on hepatocyte injured by peroxidation in vitro显示文摘INTRODUCTION Salvianolic radix,one of the most commonly usedtraditional Chinese herbs,was widely studied aboutits actions against liver injury and fibrosis,and wasone of the focuses of recent research.Salvianolic acid-A(SA-A)was an aqueous solublecomponent of Salvianolic radix.In our | Hu YY Liu CH Wang RP Liu C Liu P Zhu DY | 2000 | World Journal of Gastroenterology2000，6，3： | 15 |
| 9 | 在血压控制不良的高血压患者中使用数字化干预的家庭和在线血压管理:随机对照试验显示文摘HOME BP试验(The home and online management and evaluation of blood pressure)的目的是评估在初级预防中结合自我监测和自我管理的数字化干预在高血压管理中的作用。研究者纳入英国76个治疗中心经过治疗但血压控制不好(>140/90 mm Hg, 1 mm Hg=0.133 kPa)并能上网的患者622例,进行自动确定主要终点的公开随机对照试验。 | McMa-nus RJ Little P Stuart B Morton K Raftery J Kelly J Bradbury K Zhang J Zhu S Murray E May CR Mair FS Michie S Smith P Band R Ogburn E AllenJ Rice C Nut-tall J Williams B Yardley L 陈嘉睿(译) 叶鹏(审校) | 2021 | 中华高血压杂志2021，29，5： | 15 |
| 10 | Effects of soil moisture and plant interactions on the soil microbial community structure显示文摘 | Chen MM Zhu YG Su YH Chen BD Fu BJ Marschner P | 2007 | 中国生物学文摘2007，21，6： | 13 |
| 11 | TOLERANCE ANALYSIS OF A PLANETARY GEAR REDUCER UNDER CAD CIRCUMSTANCE显示文摘Tolerance analysis of a planetary reducer is conducted. By focusing the serially-arrangedparts in the central line and setting an appropriate dimension as a 'gap', worst-case tolerance analysismethod and statistical (RSS) tolerance analysis are used, and then a tolerance-analyzing tool CE/TOLis introduced. The acceptable value range of the 'gap' is from 1.5 mm to 3.5 mm. While worst-caseanalysis rejects the design, RSS accepts it by a more realistic result with the law of probability accounted.With the help of CE/TOL and CAD software Pro/E, all components’ dimensions and tolerances areassigned and modified, and more detailed and more comprehensible results are gives out. | Zhu Fumin Li Wanli Maropoulos P G | 2005 | Chinese Journal of Mechanical Engineering2005，18，3： | 11 |
| 12 | Integrating green supply chain management into an embryonic eco-industrial development: a case study of the Guitang Group显示文摘 | Qinghua Zhu Raymond P Cote | 2004 | Journal of Cleaner Production2004，，8： | 2 |
| 13 | NLRP6调节肠道抗病毒天然免疫效应显示文摘核苷酸结合寡聚化结构域(nucleotide-binding oligomerization domain,NOD)样受体含有的pyrin结构域蛋白6(nucleotide-binding oligomerization domain-like receptor 6,NLRP6),其分子有3个主要结构域,即N端的Pyrin结构域、中部的NOD结构域和C端的亮氨酸富集重复结构域(leucine-rich repeat domain,LRR)。NLRP6在肠道中高表达在维持肠道微生物稳态和抗细菌免疫方面发挥重要作用,但其在肠道病毒感染过程中作用仍未知,作者应用脑心肌炎病毒(encephalomyocarditis virus,EMCV)感染模型对其展开研究。 | 李天亮 韩超峰 WANG P ZHU S YANG L | 2016 | 中国肿瘤生物治疗杂志2016，23，1： | 2 |
| 14 | Microstructural Analysis of Ultrasonic Welded AA6061 by Electron Backscattered Diffraction显示文摘Ultrasonic welding can be used to join plastic and metal through high-frequency (more than 20 kHz) acoustic vibrations. Aluminium alloy is widely used in electronics, automotive and aerospace. The mechanical vibrations used during ultrasonic metal welding are introduced horizontally. During ultrasonic metal welding, a complex process is triggered involving static forces, oscillating shearing forces and a moderate temperature increase in the welding area. As the energy is introduced to the weld zone, there are three important phenomena occurring which are surface effect, volume effect and thermal effect. As it is known, microstructure is directly linked to the mechanical properties including fatigue resistance, fatigue life and fracture strength. So the microstructure analysis is important to evaluate the ultrasonically welded aluminium alloy’s properties. Also, mechanical properties of metal sheets, such as plastic anisotropy and formability, can be improved by a proper crystallographic texture control. That means the texture has great influence on the plastic anisotropy of the final recrystallized sheets. Optical microscopy (OM) can be used for showing the grain size and grain shape. However, to examine the relationship between mechanical behaviour and microstructure of the weldment, optical microscopy(OM) is not sufficient. OM cannot delineate a grain structure in the weld zone. The etched surface exhibited granularity at the micron level, but it was not clear if that reflected the grain structure. Electron backscatter diffraction (EBSD) in an SEM has become the most widely used technique for determination of microtexture. In this research, high-resolution electron backscatter diffraction is used to study the effects of the vibration on the evolution of microstructure in AA6061. The orientation image maps (OIM), polar figures (PF), and orientation distribution functions (ODF) of the samples are obtained. The characteristics of the crystallographic orientation, the grain structure and the grain boundary are analysed to find the effect of ultrasonic vibration on the microstructure and texture of the bond. The ultrasonic vibration will lead to exceptional refinement of grains to a micron level along the bond area and affect the crystallographic orientation. The grain size of upper foil is much smaller than that of the lower foil. And ultrasonic vibration results in a very weak texture with some characteristic intensity of a rotated cube-orientation and the Brass-orientation and S-orientation. In the lower foil, there is no much influence of the ultrasonic vibration. So there is very strong cube orientation in the lower foil. | Zhu Z Wynne B P Ghassemieh E Siddiq A | 2009 | 稀有金属材料与工程2009，38，A03： | 2 |
| 15 | Reference surface element modeling of composite plate/shell delamination buckling and postbuckling 显示文摘 | ZHU Ju-fen ZHENG Gang HOWSON W P | 2003 | Compos Struct2003，61，3： | 2 |
| 16 | Co-coercivity and its role in the convergence of iterative schemes for solving variational inequalities显示文摘 | Zhu D L Marcotte P | 1996 | SIAM J Optim1996，6，3： | 2 |
| 17 | Multiple dimensions of cardiopulmonary dyspnea显示文摘背景呼吸困难感觉的当前的理论假定 dyspnea.However 的一个多维的概念,它在有心肺的呼吸困难的病人的有效性一直不是 investigated.Methods 合并呼吸不快,感情方面的方面,和行为的项目的感觉经验的自发地报导的描述符的一张呼吸症状清单与气喘予 396 个病人被以,长期的妨碍的肺的疾病( COPD ),弥漫的 parenchymal 肺疾病,肺的脉管的 | HAN Jiang-na XIONG Chang-ming YAO Wei FANG Qiu-hong ZHU Yuan-jue CHENG Xian-sheng Karel P Van de Woestijne | 2011 | Chinese Medical Journal2011，，20： | 2 |
| 18 | Atom transfer radical polymerization of methyl methacrylate by silica gel supported copper bromide/multidentate amine 显示文摘 | Shen Y Q Zhu S P Zeng F Q | 2000 | Macromolecules2000，33，15： | 1 |
| 19 | Effects of incubation temperatures on embryonic development in the Asian yellow pond turtle 显示文摘 | Zhu X P Wei C Q Zhao W H | 2006 | Aquaculture2006，259，： | 1 |
| 20 | A surver on delayed feedback control of chaos 显示文摘 | Tian Y P Zhu J D Chen G R | 2005 | Journal of Control Theory and Application2005，3，4： | 1 |
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