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| 1 | Wafer-scale synthesis of monolayer WS2 for high-performance flexible photodetectors by enhanced chemical vapor deposition显示文摘 | Changyong Lan Ziyao Zhou Zhifei Zhou Chun Li Lei Shu Lifan Shen Dapan Li Ruoting Dong SenPo Yip Johnny C. Ho | 2018 | Nano Research2018，11，6： | 12 |
| 2 | A transgene-free method for rapid and efficient generation of precisely edited pigs without monoclonal selection显示文摘Gene-edited pigs for agricultural and biomedical applications are typically generated using somatic cell nuclear transfer(SCNT).However, SCNT requires the use of monoclonal cells as donors, and the time-consuming and laborious monoclonal selection process limits the production of large populations of gene-edited animals. Here, we developed a rapid and efficient method named RE-DSRNP(reporter RNA enriched dual-sg RNA/CRISPR-Cas9 ribonucleoproteins) for generating gene-edited donor cells. RE-DSRNP takes advantage of the precise and efficient editing features of dual-sg RNA and the high editing efficiency, low off-target effects, transgene-free nature, and low cytotoxic characteristics of reporter RNA enriched RNPs(CRISPR-Cas9ribonucleoproteins), thus eliminating the need for the selection of monoclonal cells and thereby greatly reducing the generation time of donor cells from 3–4 weeks to 1 week, while also reducing the extent of apoptosis and chromosomal aneuploidy of donor cells. We applied RE-DSRNP to produce cloned pigs bearing a deletion edit of the wild-type p53-induced phosphatase 1(WIP1)gene: among 32 weaned cloned pigs, 31(97%) carried WIP1 edits, and 15(47%) were homozygous for the designed fragment deletion, and no off-target event was detected. The WIP1 knockout(KO) pigs exhibited male reproductive disorders, illustrating the utility of RE-DSRNP for rapidly generating precisely edited animals for functional genomics and disease research. REDSRNP's strong editing performance in a large animal and its marked reduction in the required time for producing SCNT donor cells support its application prospects for rapidly generating populations of transgene-free cloned animals. | Kui Xu Xiuling Zhang Zhiguo Liu Jinxue Ruan Changjiang Xu Jingjing Che Ziyao Fan Yulian Mu Kui Li | 2022 | Science China(Life Sciences)2022，65，8： | 9 |
| 3 | Electro-mechanically controlled assembly of reconfigurable 3D mesostructures and electronic devices based on dielectric elastomer platforms显示文摘The manufacture of 3D mesostructures is receiving rapidly increasing attention,because of the fundamental significance and practical applications across wide-ranging areas.The recently developed approach of buckling-guided assembly allows deterministic formation of complex 3D mesostructures in a broad set of functional materials;with feature sizes spanning nanoscale to centimeter-scale.Previous studies mostly exploited mechanically controlled assembly platforms using elastomer substrates;which limits the capabilities to achieve on-demand local assembly;and to reshape assembled mesostructures into distinct 3D configurations.This work introduces a set of design concepts and assembly strategies to utilize dielectric elastomer actuators as powerful platforms for the electro-mechanically controlled 3D assembly.Capabilities of sequential-local loading with desired strain distributions allow access to precisely tailored 3D mesostructures that can be reshaped into distinct geometries,as demonstrated by experimental and theoretical studies of?30 examples.A reconfigurable inductive-capacitive radio-frequency circuit consisting of morphable 3D capacitors serves as an application example. | Wenbo Pang Xu Cheng Haojie Zhao Xiaogang Guo Ziyao Ji Guorui Li Yiming Liang Zhaoguo Xue Honglie Song Fan Zhang Zheng Xu Lei Sang Wen Huang Tiefeng Li Yihui Zhang | 2020 | National Science Review2020，7，2： | 8 |
| 4 | Anticancer Activities and the Drug Targets of Botanical Saponins from a Medicinal Herb,Gynostemma Pentaphyllum显示文摘Triterpenoid saponins are metabolites produced in most plant species through complex biosynthetic pathways.They play important roles to humansowing to their diverse medicinal | W.L.Wendy HSIAO William Chi Shing TAI Ziyao MO Pui Kei WU | 2008 | Journal of Acupuncture and Tuina Science2008，6，5： | 6 |
| 5 | Long-term,multidomain analyses to identify the breed and allelic effects in MSTN-edited pigs to overcome lameness and sustainably improve nutritional meat production显示文摘Beef and mutton production has been aided by breeding to integrate allelic diversity for myostatin(MSTN),but a lack of diversity in the MSTN germplasm has limited similar advances in pig farming.Moreover,insurmountable challenges with congenital lameness and a dearth of data about the impacts of feed conversion,reproduction,and meat quality in MSTN-edited pigs have also currently blocked progress.Here,in a largest-to-date evaluation of multiple MSTN-edited pig populations,we demonstrated a practical alternative edit-site-based solution that overcomes the major production obstacle of hindlimb weakness.We also provide long-term and multidomain datasets for multiple breeds that illustrate how MSTN-editing can sustainably increase the yields of breed-specific lean meat and the levels of desirable lipids without deleteriously affecting feed-conversion rates or litter size.Apart from establishing a new benchmark for the data scale and quality of genome-edited animal production,our study specifically illustrates how gene-editing site selection profoundly impacts the phenotypic outcomes in diverse genetic back-grounds. | Ziyao Fan Zhiguo Liu Kui Xu Tianwen Wu Jinxue Ruan Xinmin Zheng Shideng Bao Yulian Mu Tad Sonstegard Kui Li | 2022 | Science China(Life Sciences)2022，65，2： | 5 |
| 6 | The quality traceability system for prefabricated buildings using blockchain:An integrated framework显示文摘The quality traceability of precast components has largely affected the widespread adoption of prefabricated buildings.Blockchain technology provides an effective solution to change the centralized storage mode of traditional traceability system and its related disadvantages.In this paper,we propose a framework of quality traceability system for precast components based on blockchain technology.The system framework adopts a hybrid blockchain architecture and dual storage mode,defines three types of smart contracts,and creates an interactive and efficient source tracing query method,which could effectively achieve the goals of decentralization,openness,and non-tamperability,as well as efficient traceability. | Ziyao ZHANG Zhenmin YUAN Guodong NI Han LIN Yujie LU | 2020 | Frontiers of Engineering Management2020，7，4： | 5 |
| 7 | Screening of phenolic compounds in australian grown grapes and their potential antioxidant activities显示文摘Grapes(Vitis Vinifera)are one of the world's most utilised and prized fruit.Grapes are a great source of antioxidants due to the abundance of phenolic compounds.Grape pulp is the main part of the grape being consumed.The pulp of five Australian grown grapes–Dawn Seedless(DS),Calmeria(CG),Golden Globe(GG),Menindee Seedless(MS),and Thompson Seedless(TS)will be qualitatively and quantitatively analysed for its phenolic composition and antioxidant capacity.The general trend followed:GG>TS>MS>DS>CG,and the phenolic content of the pulp also presented a significant positive correlation with the antioxidant capacity.GG revealing the highest levels of TPC(4.31±0.11 mg GAE/g)and TFC(0.48±0.09 mg QE/g)while TS were highest in TTC(0.94±0.12 mg CE/g).Similarly,GG exhibited higher antioxidant capacity in DPPH(5.84±0.17 mg AAE/g),FRAP(4.91±0.14 mg AAE/g),and TAC(6.78±0.12 mg AAE/g),while TS revealed highest radical scavenging ability for ABTS(4.56±0.19 mg AAE/g).The LC-ESI-QTOF-MS/MS tentatively identified 78 phenolic compounds consisting of flavonoids(36),phenolic acids(31),lignans(3),stilbenes(1),and other polyphenols(7)in five grapes samples.Ten most abundant fruit-based targeted polyphenols were quantified.GG had a higher phenolic concentration in HPLC-PDA quantification,particularly for phenolic acids(gallic acid and chlorogenic acid)and flavonoids(kaempferol).Our study provides relatively adequate information on grape pulp's phenolic content and antioxidant capacity,providing confidence and research prospects to promote grape pulp use in different food,pharmaceutical and supplement industries,and even influencing grape cultivation. | Gia Toan Vo Ziyao Liu Osbert Chou Biming Zhong Colin J.Barrow Frank R.Dunshea Hafiz A.R.Suleria | 2022 | Food Bioscience2022，47，3： | 2 |
| 8 | Distinct effects of Cu^2+-binding on oligomerization of human and rabbit prion proteins显示文摘 | Kejiang Lin Ziyao Yu Yuanhui Yu Xinli Liao Pei Huang Chenyun Guo Donghai Lin | 2015 | Acta Biochimica et Biophysica Sinica2015，47，10： | 2 |
| 9 | Laser mass spectrometry for high sensitive and multi-component analysis of exhaust gas from vehicles显示文摘Laser mass spectrometry is a newly developed method for pollutant detection. It combines resonance-enhanced multiphoton ionization (REMPI) and time-of-flight mass spectro- metry (TOF-MS). It may detect pollutants with high sensitivity, high selectivity and in a multi-component way. In this note, laser mass spectrometry was used to detect the pollutants in exhaust gases from vehicles. With one-color REMPI (at 266 nm), several aromatic hydrocarbons, including benzene, toluene, xylene, C3-benzene, etc., were detected. These substances were selectively ionized by (1+1) REMPI and their mass resolution was detected by a TOF mass spectrometer. And a quantitative analysis was achieved. | Liandi Zhang Jie Wei Haiyang Zheng Ziyao Li Zhuhong Xia Xuejun Gu Bin Zhang | 2001 | Chinese Science Bulletin2001，46，1： | 2 |
| 10 | Absence of hexavalent chromium in marine carbonates:implications for chromium isotopes as paleoenvironment proxy显示文摘The oxygenation of Earth’s atmosphere is widely regarded to have played an important role in early-life evolution.Chromium(Cr)isotopes recorded in sedimentary rocks have been used to constrain the atmospheric oxygen level(AOL)over geological times based on the fact that a positive Cr isotopic signature is linked to the presence of Cr(Ⅵ)as a result of oxidative continental weathering.However,there is no direct evidence of the presence of Cr(Ⅵ)in sedimentary rocks yet.Carbonates are most widely distributed over geological times and were thought to have incorporated Cr(Ⅵ)directly from seawater.Here,we present results of Cr valence states in carbonates which show Cr(Ⅲ)is the dominant species in all samples spanning a wide range of geological times.These findings indicate that Cr(Ⅵ)in seawater was reduced either before or after carbonate precipitation,which might have caused Cr isotopic fractionation between seawater and carbonates,or marine carbonates preferentially uptake Cr(Ⅲ)from seawater.As Cr(Ⅲ)can come from non-redox Cr cycling,which also can cause isotopic fractionation,we suggest that positively fractionated Cr isotopic values do not necessarily correspond to the rise in AOL. | Ziyao Fang Liping Qin Wei Liu Tao Yao Xiaoyan Chen Shiqiang Wei | 2021 | National Science Review2021，8，3： | 2 |
| 11 | Steady increase in water clarity in Jiaozhou Bay in the Yellow Sea from 2000 to 2018:Observations from MODIS显示文摘The Moderate Resolution Imaging Spectroradiometer(MODIS)surface reflectance data were used to analyze the temporal and spatial distribution characteristics of water clarity(Z_(sd))in the Jiaozhou Bay,Qingdao,China,in the Yellow Sea from 2000 to 2018.Z_(sd)retrieval models were regionally optimized using in-situ data with coincident MODIS images,and then were used to retrieve the Z_(sd) products in Jiaozhou Bay from 2000-2018.The analysis of the Z_(sd) results suggests that the spatial distribution of relative Z_(sd) spatial characteristics in Jiaozhou Bay was stable,being higher Z_(sd) in the southeast and a lower Z_(sd) in the northwest.The annual mean Z_(sd) in Jiaozhou Bay showed a significant upward trend,with an annual increase of approximately 0.02 m.Water depth and wind speed were important factors affecting the spatial distribution and annual variation of Z_(sd) in Jiaozhou Bay,respectively. | Ziyao YIN Junsheng LI Jue HUANG Shenglei WANG Fangfang ZHANG Bing ZHANG | 2021 | Journal of Oceanology and Limnology2021，39，3： | 2 |
| 12 | An overview of multi-antenna technologies for space-ground integrated networks显示文摘Multi-antenna technologies have already achieved a series of great successes in the development of information networks. For future space-ground integrated networks(SGINs), the traditional various kinds of separated information networks will converge to a whole fully connected information network to provide more flexible and reliable services on a world scale. Regarding their great successes in existing systems, multiantenna technologies will be of critical importance for the realization of SGINs and multi-antenna technologies are definitely one of the most important enabling technologies for future converged SGINs. In this article, a comprehensive overview on multi-antenna technologies is given. We first investigate multi-antenna technologies from a theoretical viewpoint. It is shown that we can understand multi-antenna technologies in a general and unified point of view. This fact has two-fold meanings. First, the research on multi-antennas can help us understand the relationships between different technologies e.g., OFDMA, CDMA, etc. On the other hand,multi-antenna technologies are easy to integrate into various information systems. Following that, we discuss in depth the potentials and challenges of the multi-antenna technologies on different platforms and in different applications case by case. More specifically, we investigate spaceborne multi-antenna technologies, airborne multi-antenna technologies, shipborne multi-antenna technologies, etc. Moreover, the combinations of multiantenna technologies with other advanced wireless technologies e.g., physical layer network coding, cooperative communication, etc., are also elaborated. | Lei GAO Shuo ZHANG Ziyao LIU Jinyong LIN Shuai WANG Chengwen XING | 2016 | Science China Earth Sciences2016，59，12： | 2 |
| 13 | Formation of a new intermediate phase and its evolution toward θ’ during aging of pre-deformed Al-Cu alloys显示文摘The frequent occurrence of hitherto unknown phase Pre-θ′-2 and unusual 1.5 cθ′thick θ′precipitate was observed by atomic-resolution scanning transmission electron microscopy in the well-studied Al-Cu alloys. This phenomenon is associated with heterogeneous precipitate nucleation and growth on preexisting dislocations introduced by slight deformation prior to aging. In this study, the precise structure details of Pre-θ′-2 was determined by atomic scale imaging, image simulation based on image forming theories and first principle calculations. Pre-θ′-2 has a well-defined ordered structure sandwiched between two 2 aAl(~1.5 cθ′) spaced Cu layers on {200}Alplanes. The strong structural similarities between Pre-θ′-2 and 1.5 cθ′ thick θ′ in terms of interfacial structure and thickness, coupled with energetic calculations and preliminary in-situ observations, lead us to propose a new precipitation path toward key strengthening phase θ′ | Peipei Ma Chunhui Liu Ziyao Ma Lihua Zhan Minghui Huang | 2019 | Journal of Materials Science & Technology2019，35，5： | 2 |
| 14 | Three dammarane-type saponins fromGynostemmapentaphyllum显示文摘 | LIU Xin YE Wencai MO Ziyao | 2005 | Planta Medica2005，71，9： | 1 |
| 15 | The Solar Upper Transition Region Imager(SUTRI)Onboard the SATech-01 Satellite显示文摘The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the on-orbit performance of our newly developed Sc/Si multi-layer reflecting mirror and the 2k×2k EUV CMOS imaging camera and to take full-disk solar images at the Ne VII 46.5 nm spectral line with a filter width of~3 nm.SUTRI employs a Ritchey-Chrétien optical system with an aperture of 18 cm.The on-orbit observations show that SUTRI images have a field of view of~416×416 and a moderate spatial resolution of~8″without an image stabilization system.The normal cadence of SUTRI images is 30 s and the solar observation time is about16 hr each day because the earth eclipse time accounts for about 1/3 of SATech-01's orbit period.Approximately15 GB data is acquired each day and made available online after processing.SUTRI images are valuable as the Ne VII 46.5 nm line is formed at a temperature regime of~0.5 MK in the solar atmosphere,which has rarely been sampled by existing solar imagers.SUTRI observations will establish connections between structures in the lower solar atmosphere and corona,and advance our understanding of various types of solar activity such as flares,filament eruptions,coronal jets and coronal mass ejections. | Xianyong Bai Hui Tian Yuanyong Deng Zhanshan Wang Jianfeng Yang Xiaofeng Zhang Yonghe Zhang Runze Qi Nange Wang Yang Gao Jun Yu Chunling He Zhengxiang Shen Lun Shen Song Guo Zhenyong Hou Kaifan Ji Xingzi Bi Wei Duan Xiao Yang Jiaben Lin Ziyao Hu Qian Song Zihao Yang Yajie Chen Weidong Qiao Wei Ge Fu Li Lei Jin Jiawei He Xiaobo Chen Xiaocheng Zhu Junwang He Qi Shi Liu Liu Jinsong Li Dongxiao Xu Rui Liu Taijie Li Zhenggong Feng Yamin Wang Chengcheng Fan Shuo Liu Sifan Guo Zheng Sun Yuchuan Wu Haiyu Li Qi Yang Yuyang Ye Weichen Gu Jiali Wu Zhe Zhang Yue Yu Zeyi Ye Pengfeng Sheng Yifan Wang Wenbin Li Qiushi Huang Zhong Zhang | 2023 | Research in Astronomy and Astrophysics2023，23，6： | 1 |
| 16 | Growth behavior of CVD diamond films with enhanced electron field emission properties over a wide range of experimental parameters显示文摘In this study, diamond films were synthesized on silicon substrates by microwave plasma enhanced chemical vapor deposition(CVD) over a wide range of experimental parameters. The effects of the microwave power,CH_4/H_2 ratio and gas pressure on the morphology, growth rate, composition, and quality of diamond films were investigated by means of scanning electron microscope(SEM), X-ray diffraction(XRD), Raman spectroscopy and X-ray photoelectron spectroscopy(XPS). A rise of microwave power can lead to an increasing pyrolysis of hydrogen and methane, so that the microcrystalline diamond film could be synthesized at low CH_4/H_2 levels. Gas pressure has similar effect in changing the morphology of diamond films, and high gas pressure also results in dramatically increased grain size. However,diamond film is deteriorated at high CH_4/H_2 ratio due to the abundant graphite content including in the films. Under an extreme condition of high microwave power of 10 kW and high CH_4 concentration, a hybrid film composed of diamond/graphite was successfully formed in the absence of N_2 or Ar,which is different from other reports. This composite structure has an excellent measured sheet resistance of 10-100 Ω/Sqr. which allows it to be utilized as field electron emitter. The diamond/graphite hybrid nanostructure displays excellent electron field emission(EFE) properties with a low turn-on field of 2.17 V/μm and β= 3160, therefore it could be a promising alternative in field emission applications. | Xinyi Jia Nan Huang Yuning Guo Lusheng Liu Peng Li Zhaofeng Zhai Bing Yang Ziyao Yuan Dan Shi Xin Jiang | 2018 | Journal of Materials Science & Technology2018，34，12： | 1 |
| 17 | Crystalline InGaZnO quaternary nanowires with superlattice structure for high-performance thin-film transistors显示文摘Amorphous indium-gallium-zinc oxide (a-IGZO) materials have been widely explored for various thin-film transistor (TFT) applications;however, their device performance is still restricted by the intrinsic material issues especially due to their non-crystalline nature. In this study, highly crystalline superlattice-structured IGZO nanowires (NWs) with different Ga concentration are successfully fabricated by enhanced ambient-pressure chemical vapor deposition (CVD). The unique superlattice structure together with the optimal Ga concentration (i.e., 31 at.%) are found to effectively modulate the carrier concentration as well as efficiently suppress the oxygen vacancy formation for the superior NW device performance. In specific, the In1.8Ga1.8Zn2.4O7 NW field-effect transistor exhibit impressive device characteristics with the average electron mobility of ~ 110 cm^2-V^-1·s^-1 and on/off current ratio of ~ 10^6. Importantly, these NWs can also be integrated into NW parallel arrays for the construction of high-performance TFT devices, in which their performance is comparable to many state-of-the-art IGZO TFTs. All these results can evidently indicate the promising potential of these crystalline superlattice-structured IGZO NWs for the practical utilization in next-generation metal-oxide TFT device technologies. | Fangzhou Li SenPo Yip Ruoting Dong Ziyao Zhou Changyong Lan Xiaoguang Liang Dapan Li You Meng Xiaolin Kang Johnny C. Ho | 2019 | Nano Research2019，12，8： | 1 |
| 18 | A Comparative Investigation of Single Crystal and Polycrystalline Ni-Rich NCMs as Cathodes for Lithium-Ion Batteries显示文摘Nickel-rich LiNi_(1-x-y)Co_(x)Mn_(y)O_(2)(NCM,1-x-y≥0.6)is known as a promising cathode material for lithium-ion batteries since its superiority of high voltage and large capacity.However,polycrystalline Ni-rich NCMs suffer from poor cycle stability,limiting its further application.Herein,single crystal and polycrystalline LiNi_(0.84)Co_(0.07)Mn_(0.09)O_(2)cathode materials are compared to figure out the relation of the morphology and the electrochemical storage performance.According to the Li^(+)diffusion coefficient,the lower capacity of single crystal samples is mainly ascribed to the limited Li+diffusion in the large bulk.In situ XRD illustrates that the polycrystalline and single crystal NCMs show a virtually identical manner and magnitude in lattice contraction and expansion during cycling.Also,the electrochemically active surface area(ECSA)measurement is employed in lithium-ion battery study for the first time,and these two cathodes show huge discrepancy in the ECSA after the initial cycle.These results suggest that the single crystal sample exhibits reduced cracking,surface side reaction,and Ni/Li mixing but suffers the lower Li^(+)diffusion kinetics.This work offers a view of how the morphology of Ni-rich NCM effects the electrochemical performance,which is instructive for developing a promising strategy to achieve good rate performance and excellent cycling stability. | Xianming Deng Rui Zhang Kai Zhou Ziyao Gao Wei He Lihan Zhang Cuiping Han Feiyu Kang Baohua Li | 2023 | Energy & Environmental Materials2023，6，3： | 1 |
| 19 | Electrostatic Interaction Tailored Anion-Rich Solvation Sheath Stabilizing High-Voltage Lithium Metal Batteries显示文摘Through tailoring interfacial chemistry,electrolyte engineering is a facile yet effective strategy for highperformance lithium(Li)metal batteries,where the solvation structure is critical for interfacial chemistry.Herein,the effect of electrostatic interaction on regulating an anion-rich solvation is firstly proposed.The moderate electrostatic interaction between anion and solvent promotes anion to enter the solvation sheath,inducing stable solid electrolyte interphase with fast Li+transport kinetics on the anode.This asdesigned electrolyte exhibits excellent compatibility with Li metal anode(a Li deposition/stripping Coulombic efficiency of 99.3%)and high-voltage LiCoO_(2) cathode.Consequently,the 50μm-thin Li||high-loading LiCoO_(2) cells achieve significantly improved cycling performance under stringent conditions of high voltage over 4.5 V,lean electrolyte,and wide temperature range(-20 to 60℃).This work inspires a groundbreaking strategy to manipulate the solvation structure through regulating the interactions of solvent and anion for highperformance Li metal batteries. | Junru Wu Ziyao Gao Yao Wang Xu Yang Qi Liu Dong Zhou Xianshu Wang Feiyu Kang Baohua Li | 2022 | Nano-Micro Letters2022，14，9： | 1 |
| 20 | Reflections on the system of evaluation of gene-edited livestock显示文摘The rapid development of biotechnology has provided a greater understanding of the biological functions of major candidate genes that have important functions regarding economic traits,and new materials for livestock breeding have been obtained through gene editing(GE)and embryo manipulation with the purpose of improving quality and output and reducing the costs and risk of disease.Public concerns,particularly over safety risks and production performance,must be addressed.Evaluation is the most important component of the regulation of gene-edited livestock and is a crucial guarantee of public safety before the marketing of geneedited animal products.Here,the system of evaluation of gene-edited livestock is discussed in terms of public safety and production performance.The search for safe and ethical applications in the GE of livestock,a case-by-case evaluation strategy,and classification and simplification are used in order to promote a more efficient,objective,comprehensive and operable evaluation system. | Ziyao FAN Tianwen WU Kui WU Yulian MU Kui LI | 2020 | Frontiers of Agricultural Science and Engineering2020，7，2： | 1 |
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