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| 1 | In vivo radiometric analysis of glucose uptake and distribution in mouse bone显示文摘Bone formation and remodeling occurs throughout life and requires the sustained activity of osteoblasts and osteoclasts,particularly during periods of rapid bone growth.Despite increasing evidence linking bone cell activity to global energy homeostasis,little is known about the relative energy requirements or substrate utilization of bone cells.In these studies,we measured the uptake and distribution of glucose in the skeleton in vivo using positron-emitting^(18)F-fluorodeoxyglucose([^(18)F]-FDG) and non-invasive,high-resolution positron emission tomography/computed tomography(PET/CT) imaging and ex vivo autoradiography.Assessment of [^(18)F]-FDG uptake demonstrated that relative to other tissues bone accumulated a significant fraction of the total dose of the glucose analog.Skeletal accumulation was greatest in young mice undergoing the rapid bone formation that characterizes early development.PET/CT imaging revealed that [^(18)F]-FDG uptake was greatest in the epiphyseal and metaphyseal regions of long bones,which accords with the increased osteoblast numbers and activity at this skeletal site.Insulin administration significantly increased skeletal accumulation of [^(18)F]-FDG,while uptake was reduced in mice lacking the insulin receptor specifically in osteoblasts or fed a high-fat diet.Our results indicated that the skeleton is a site of significant glucose uptake and that its consumption by bone cells is subject to regulation by insulin and disturbances in whole-body metabolism. | Meredith L Zoch Diane S Abou Thomas L Clemens Daniel LJ Thorek Ryan C Riddle | 2016 | Bone Research2016，4，1： | 9 |
| 2 | Spray forming of hypereuteetic A1-Si alloys显示文摘 | CUI C SCHULZ A SCHIMANSKI K ZOCH H W | 2009 | Journal of Materials Processing Technology2009，209，3： | 1 |
| 3 | Thermoregulation and rheological properties of blood in primary Raynaud' s phenomenonand the vibration-induced white-finger syndrome显示文摘 | Ziegler S Zoch C Gschwandtner M | 2005 | Int Arch Occup Envion Heaith2005，78，3： | 1 |
| 4 | Predisposing factors and clinical features of eczema herpeticum:a retrospective analysis of 100 cases显示文摘 | Wollenberg A Zoch C Wetzel S | 2003 | J Am Acad Dermatol2003，49，2： | 1 |
| 5 | Phase diagram of degenerate exciton systems显示文摘 | LAI C W ZOCH J GOSSARD A C | 2004 | Science2004，303，5657： | 1 |
| 6 | Phase diagram of degenerate exciton systems 显示文摘 | Lai C W Zoch J Gossaxd A C | 2004 | Science2004，303，： | 1 |
| 7 | Predisposing factors and clinical features of eczema herpeticum: a retrospective analysis of 100 cases显示文摘 | Wollenberg A Zoch C Wetzel S | 2003 | J Am Acad Dermatol2003，49，2： | 1 |
| 8 | In vitro kinematics of fixedversus mobile bearing in unicondylar knee arthroplasty 显示文摘 | Ettinger M Zoch JM Becher C | 2015 | Arch Orthop Trauma Surg2015，135，6： | 1 |
| 9 | Spray forming of hypereutectic A1-Si alloys显示文摘 | CUI C SCHULZ A SCH1MANSKI K ZOCH H W | 2009 | Journal of Materials Processing Technology2009，209，11： | 1 |
| 10 | Spray forming of hypereutectic A1-Si alloys 显示文摘 | Cui C Schulz A Schimanski K Zoch H W | 2009 | Journal of Materials Processing Technology2009，209，11： | 1 |
| 11 | Predisposing factors and clinical features of eczema herpeticum:a retrospective analysis of 100 cases显示文摘 | Wollenberg A Zoch C Wetzel S | 2003 | J Am Acad Dermatol2003，49，2： | 1 |
| 12 | Spray forming of hypereutectic A1-Si alloys 显示文摘 | CUI C SCHULZ A SCHIMANSKI K ZOCH H W | 2009 | Journal of Materials Processing and Technology2009，209，52： | 1 |
| 13 | Thermoregulation and rheological properties of blood in primary Raynaud's phenomenon and the vibration-induced white-finger syndrome显示文摘 | Ziegler S Zoch C Gschwandtner M Eckhardt G Windberger U Minar E Rudiger H Osterode W | 2005 | Int Arch Occup Environ Health2005，78，3： | 1 |
| 14 | Phase diagram of degenerate exciton systems显示文摘 | Lai C W Zoch J Gossard A C | 2004 | Science2004，303，： | 1 |
| 15 | Predisposing factors and clinical features of eczema herpeticum-a retrospective analysis of 100cases显示文摘 | Wollenberg A Zoch C Wetzel S | 2003 | Amer Acad Dermatol2003，49，2： | 1 |
| 16 | Predisposing factors and clinical features of eczema herpeticum : a retrospective analysis of 100 cases显示文摘 | WOLLENBERG A ZOCH C WETZEL S | 2003 | J Am Acad Demlatol2003，49，2： | 1 |
| 17 | 改进零件几何形状减小热处理畸变显示文摘因热处理时发生畸变,加之精度要求较高,零件热处理后通常都要进行机加工。由于通过机加工修正变形的成本太高,所以应尽可能减小零件的热处理畸变。本文研究结果证明,零件的热处理畸变与其几何形状有关。首先概述使零件几何形状成为畸变倾向重要载体的物理效应。其次,以复杂的汽车零件为例说明零件几何形状影响畸变的程度。最后介绍一种能更有效控制系统畸变的新途径。 | C Andersch J Schwarzer F Hoffmann H-W Zoch 顾剑锋 | 2012 | 热处理2012，27，3： | 0 |
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