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| 1 | Stamen specification and anther development in rice显示文摘Male reproductive development is a complex biological process which includes the formation of the stamen with differentiated anther tissues, in which microspores/pollens are generated, then anther dehiscence and subsequently pollination. Stamen specification and anther development involve a number of extraordinary events such as meristem transition, cell division and differentiation, cell to cell communication, etc., which need the cooperative interaction of sporophytic and gametophytic genes. The advent of various tools for rice functional gene identification, such as complete genome sequence, genome-wide microarrays, collections of mutants, has greatly facilitated our understanding of mechanisms of rice stamen specification and anther development. Male sterile lines are critical for hybrid rice breeding, therefore understanding these processes will not only contribute greatly to the basic knowledge of crop developmental biology, but also to the development of new varieties for hybrid rice breeding in the future. | ZHANG DaBing WILSON Zoe A | 2009 | Chinese Science Bulletin2009，54，14： | 40 |
| 2 | Anther and pollen development:A conserved developmental pathway显示文摘Pollen development is a critical step in plant development that is needed for successful breeding and seed formation.Manipulation of male fertility has proved a useful trait for hybrid breeding and increased crop yield.However,although there is a good understanding developing of the molecular mechanisms of anther and pollen anther development in model species,such as Arabidopsis and rice,little is known about the equivalent processes in important crops.Nevertheless the onset of increased genomic information and genetic tools is facilitating translation of information from the models to crops,such as barley and wheat;this will enable increased understanding and manipulation of these pathways for agricultural improvement. | José Fernndez Gmez Behzad Talle Zoe A Wilson | 2015 | Journal of Integrative Plant Biology2015，57，11： | 33 |
| 3 | Aplastic anemia and severe pancytopenia during treatment with peg-interferon,ribavirin and telaprevir for chronic hepatitis C显示文摘Telaprevir and Boceprevir are the first direct acting antivirals approved for chronic hepatitis C in combination with peg-interferon alfa and ribavirin.Pancytopenia due to myelotoxicity caused by these drugs may occur,but severe hematological abnormalities or aplastic anemia(AA) have not been described.We collected all cases of severe pancytopenia observed during triple therapy with telaprevir in four Spanish centers since approval of the drug in 2011.Among 142 cirrhotic patients receiving treatment,7 cases of severe pancytopenia(5%) were identified and three were consistent with the diagnosis of AA.Mean age was 59 years,five patients had compensated cirrhosis and two patients had severe hepatitis C recurrence after liver transplantation.Severe pancytopenia was diagnosed a median of 10 wk after the initiation of therapy.Three patients had pre-treatment hematological abnormalities related to splenomegaly.In six patients,antiviral treatment was interrupted at the onset of hematological abnormalities.Two patients died due to septic complications and one patient due to acute alveolar hemorrhage.The remaining patients recovered.Severe pancytopenia and especially AA,are not rare during triple therapy with telaprevir in patients with advanced liver disease.Close monitoring is imperative in this setting to promptly detect serious hematological disorders and to prevent further complications. | Sabela Lens Jose L Calleja Ana Campillo Jose A Carrion Teresa Broquetas Christie Perello Juan de la Revilla Zoe Marino Maria-Carlota Londono Jose M Sanchez-Tapias Alvaro Urbano-Ispizua Xavier Forns | 2015 | World Journal of Gastroenterology2015，21，17： | 4 |
| 4 | Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function 显示文摘 | Zoe A Robert SW | 2004 | Arch Neurol2004，61，5： | 1 |
| 5 | From D to T - Determiner incorporation and the creation of Tense 显示文摘 | Simpson A Wu Zoe | 2002 | Journal of East Asian Linguistics2002，，： | 1 |
| 6 | Studies on amidated pectins as potential carriers in colonic drug delivery 显示文摘 | Zoe W John F David A | 1997 | J Pharm Pharmacol1997，49，： | 1 |
| 7 | A position/force control for a robot finger with soft tip and uncertain kinematics显示文摘 | ZOE D SUGURU A | 2002 | Journal of Robotic Systems2002，44，4： | 1 |
| 8 | Enhancing AMPK activationduring ischemia protects the diabetic heart against reperfusion injury 显示文摘 | Marta A Paiva Zoe Rutter-Locher | 2011 | Am J Physiol Heart Circ Physiol2011，300，6： | 1 |
| 9 | Cell-cycle dysregulation and anticancer therapy显示文摘 | ZOE A S MATTHEW D W JENNIFER A P | 2003 | Trends Pharmacol Sci2003，24，： | 1 |
| 10 | Combinations of simple baseline variables accurately predict sustained virological response in patients with recurrent hepatitis C after liver transplantation显示文摘 | Gonzalo Crespo José A. Carrión Mairene Coto-Llerena Zoe Mari?o Sabela Lens Sofía Pérez-del-Pulgar Montserrat García-Retortillo Rosa Miquel Jaime Bosch Miquel Navasa Xavier Forns | 2013 | Journal of Gastroenterology2013，，6： | 1 |
| 11 | Cellcycle dysregulation and anticancer therapy 显示文摘 | Zoe A Stewart Matthew D Westfall Jennifer A Pietenpol | 2003 | Trends in Pharmacological Sciences2003，24，2： | 1 |
| 12 | Cell-cycle dysregulation and anticancer therapy 显示文摘 | Zoe A Stewart Matthew D | 2004 | Trends in pharmacological Sciences2004，24，2： | 1 |
| 13 | Cell cycle checkpoints as therapeutic targets显示文摘 | Zoe A Stewart L Jennifer A | 1999 | J Mammary Gland Biol Neoplasia1999，4，4： | 1 |
| 14 | Hyperdense artery sign, symptomatic infarct swelling and effect of alteplase in acute ischaemic stroke显示文摘Background Alteplase improves functional outcomes of patients with acute ischaemic stroke,but its effects on symptomatic infarct swelling,an adverse complication of stroke and the influence of CT hyperdense artery sign(HAS)are unclear.This substudy of the Third International Stroke Trial aimed to investigate the association between HAS and symptomatic infarct swelling and effect of intravenous alteplase on this association.Methods We included stroke patients whose prerandomisation scan was non-contrast CT.Raters,masked to clinical information,assessed baseline(prerandomisation)and follow-up(24-48 hours postrandomisation)CT scans for HAS,defined as an intracranial artery appearing denser than contralateral arteries.Symptomatic infarct swelling was defined as clinically significant neurological deterioration≤7 days after stroke with radiological evidence of midline shift,effacement of basal cisterns or uncal herniation.Results Among 2961 patients,HAS presence at baseline was associated with higher risk of symptomatic infarct swelling(OR 2.21;95% CI 1.42 to 3.44).Alteplase increased the risk of swelling(OR 1.69;95% CI 1.11 to 2.57),with no difference between patients with and those without baseline HAS(p=0.49).In patients with baseline HAS,alteplase reduced the proportion with HAS at follow-up(OR 0.67;95% CI 0.50 to 0.91),where HAS disappearance was associated with reduced risk of swelling(OR 0.25,95% CI 0.14 to 0.47).Conclusion Although alteplase was associated with increased risk of symptomatic infarct swelling in patients with or without baseline HAS,it was also associated with accelerated clearance of HAS,which in return reduced swelling,providing further mechanistic insights to underpin the benefits of alteplase. | Simiao Wu Grant Mair Geoff Cohen Zoe Morris Anders von Heijne Nick Bradey Lesley Cala Andre Peeters Andrew J Farrall Alessandro Adami Gillian Potter Ming Liu Richard I Lindley Peter A G Sandercock Joanna M Wardlaw the IST-3 Collaborative Group | 2021 | Stroke & Vascular Neurology2021，6，2： | 1 |
| 15 | Duloxetin, a serotonin and noradrenaline reuptake inhibitor(SNRI) for the treatment ofstress urinary incontinence : A systematic review 显示文摘 | Paramananthan M Ammar A Zoe B | 2007 | Eur Urolocy2007，51，1： | 1 |
| 16 | 显示文摘 | Zoe W John F David A | 1997 | J Pharm Pharmacol1997，49，： | 1 |
| 17 | Characterisation of the selective 5-HTB receptor antagonist SB-616234-A(1 -- 1 -methanone hydrochloride): in vivo neurochemical and behaviouralevidence of anxiolytic/antidepressant activity显示文摘 | Lee A Dawson Zoe A Hughes Kathryn R Starr | 2006 | Neuropharmacology2006，50，8： | 1 |
| 18 | 4-n-nonylphenol and 17-βestradiol may induce common DNA effects in developing barnacle larvae显示文摘 | FRANCK A A ZOE B MICHAEL H D | 2002 | Environmental Pollution2002，120，： | 1 |
| 19 | The Arabidopsis MALE STERILITY1(MS1) gene is a transcriptional regulator of male gametogenesis,with homology to the PHD-finger family of transcription factors显示文摘 | Wilson S M Morroll J D | 2001 | Plant J2001，28，： | 1 |
| 20 | The Contraceptive Potential of ZP3 and ZP3 Peptides in a Primate model 显示文摘 | Margaret Paterson Zoe A Jennings Martin R Wilson | 2002 | Journal of Reproductive Immunology2002，53，： | 1 |
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