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| 1 | Correlation analysis of dual-energy CT iodine maps with quantitative pulmonary perfusion MRI显示文摘AIM:To correlate dual-energy computed tomography(DECT) pulmonary angiography derived iodine maps with parameter maps of quantitative pulmonary perfusion magnetic resonance imaging(MRI).METHODS:Eighteen patients with pulmonary perfusion defects detected on DECT derived iodine maps were included in this prospective study and additionally underwent time-resolved contrast-enhanced pulmonary MRI [dynamic contrast enhanced(DCE)-MRI].DCE-MRI data were quantitatively analyzed using a pixel-by-pixel deconvolution analysis calculating regional pulmonary blood flow(PBF),pulmonary blood volume(PBV) and mean transit time(MTT) in visually normal lung parenchyma and perfusion defects.Perfusion parameterswere correlated to mean attenuation values of normal lung and perfusion defects on DECT iodine maps.Two readers rated the concordance of perfusion defects in a visual analysis using a 5-point Likert-scale(1 = no correlation,5 = excellent correlation).RESULTS:In visually normal pulmonary tissue mean DECT and MRI values were:22.6 ± 8.3 Hounsfield units(HU);PBF:58.8 ± 36.0 mL/100 mL per minute;PBV:16.6 ± 8.5 mL;MTT:17.1 ± 10.3 s.In areas with restricted perfusion mean DECT and MRI values were:4.0 ± 3.9 HU;PBF:10.3 ± 5.5 mL/100 mL per minute,PBV:5 ± 4 mL,MTT:21.6 ± 14.0 s.The differences between visually normal parenchyma and areas of restricted perfusion were statistically significant for PBF,PBV and DECT(P < 0.0001).No linear correlation was found between MRI perfusion parameters and attenuation values of DECT iodine maps(PBF:r = 0.35,P = 0.15;PBV:r = 0.34,P = 0.16;MTT:r = 0.41,P = 0.08).Visual analysis revealed a moderate correlation between perfusion defects on DECT iodine maps and the parameter maps of DCE-MRI(mean score 3.6,k 0.45).CONCLUSION:There is a moderate visual but not statistically significant correlation between DECT iodine maps and perfusion parameter maps of DCE-MRI. | Jan Hansmann Paul Apfaltrer Frank G Zoellner Thomas Henzler Mathias Meyer Gerald Weisser Stefan O Schoenberg Ulrike I Attenberger | 2013 | World Journal of Radiology2013，5，5： | 6 |
| 2 | 质子泵抑制剂增高伏立康唑血药浓度显示文摘伏立康唑治疗药物监测与侵袭性真菌病的疗效密切相关。在侵袭性曲霉病的治疗中临床上普遍接受的伏立康唑目标治疗浓度为谷浓度1~2 mg/L,谷浓度≤5.5 mg/L可预防不良反应发生。由于不同患者伏立康唑的生物利用度有较大差异,故目标血药浓度较难达到,尤其是谷浓度。
Boyd等报道1例额叶曲霉病患者联合应用质子泵抑制剂奥美拉唑,使伏立康唑达到目标治疗浓度。 | Boyd NK Zoellner CL Swancutt MA 吴真 徐晓刚 | 2015 | 中国感染与化疗杂志2015，15，1： | 2 |
| 3 | 显示文摘 | Gilman H Zoellner E A | | J A Chem Soc0，53，： | 1 |
| 4 | Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt- versus calcium-dependent mechanisms for nitric oxide release 显示文摘 | Fulton D Babbitt B Zoellner S | 2004 | J Biol Chem2004，279，30： | 1 |
| 5 | Aktl/protein kinase Bal-pha is critical for ischemic and VEGF-mediated angiogen-esis显示文摘 | Ackah E Yu J Zoellner S | 2005 | J Clin Invest2005，115，： | 1 |
| 6 | Post-traumatic growth as outcome of a cognitive-behavioural therapy trial for motor vehicle accident survivors with PTSD显示文摘 | Zoellner T Rabe S Karl A | 2011 | Psychol Psychother2011，84，2： | 1 |
| 7 | Serum albumin is a specific inhibitor of apoptosis in human endothelial cells 显示文摘 | Zoellner H Hofler M Beckmann R | 1996 | J Cell Sci1996，109，10： | 1 |
| 8 | A role forapolipoprotein E,apolipoprotein A-I,and low densitylipoprotein receptors in cholesterol transport during re-generation and remyelination of the rat sciatic nerve显示文摘 | Boyles JK Zoellner CD Anderson LJ | | Clin Investa9890，83，3： | 1 |
| 9 | Maternal and child expressed emotion as predictors of treatment response in pediatric ob- sessive - compulsive disorder 显示文摘 | Przeworski A Zoellner LA Franklin ME | 2012 | Child Psychiatry Hum Dev2012，43，： | 1 |
| 10 | Edible film reduce surface drying of peeled carrots显示文摘 | Sagent S A Brecht J K Zoellner J J | 1995 | Proc Fla State Hort Sci1995，112，： | 1 |
| 11 | Aktl/protein kinase Balpha is critical for isehemie and VEGF-mediated angiogenesis显示文摘 | ACKAH E YU J ZOELLNER S | 2005 | J Clin Invest2005，115，： | 1 |
| 12 | Fetal morbidity and mortality after acute human parvovirus B19 infection in pregnancy:prospective evaluation of 1 018 cases显示文摘 | Enders M Weidner A Zoellner I | 2004 | Prenat Diagn2004，24，7： | 1 |
| 13 | Posttraumatic growth in clinical psychology-a critical review and introduction of a two component model 显示文摘 | Zoellner T Maercker A | 2006 | Clin Psychol Rev2006，26，11： | 1 |
| 14 | Serum albumin is a specific inhibitor of apoptosis in human endothelial cells显示文摘 | Zoellner H H6fler M Beckmann R | 1996 | J Cell Sci1996，109，10： | 1 |
| 15 | Inhibition of monoamine oxidase B by selected benzimidazole and caffeine analogues 显示文摘 | Berg D V Zoellner K R Ogunrombi M O | 2007 | Bio Org Med Chem2007，15，11： | 1 |
| 16 | Shock wave therapy versus convention- al surgery, in the treatment of calcifying tendinitis of the shouhler 显示文摘 | Rompe JD Zoellner J Nafe B | 2001 | Clin Orthop2001，387，： | 1 |
| 17 | Role of extracellu- lar phospholipases and n'lononuclear phagocytes in dissemi- nation of cryptococeosis in a murine model显示文摘 | Santangelo R Zoellner H Sorrell T | 2004 | Infeet Im- mun2004，72，4： | 1 |
| 18 | Biomonitoring of persistent organochlorine pesticides, PCDD/PCDFs and dioxin-like PCBs in blood of children from South West Germany (Baden-Wuerttemberg) from 1993 to 2003显示文摘 | Link B Gabrio T Zoellner I | 2005 | Chemosphere2005，58，9： | 1 |
| 19 | The Researcher' s Journey: Scholarly Navigation of an Academic Library Web Site 显示文摘 | McCann S Ravas T Zoellner K | 2010 | Journal of Web Librarianship2010，4，4： | 1 |
| 20 | The syphi-lis-HIV interdependency 显示文摘 | Ditzen A K Braker K Zoellner K H Teichmann D | 2005 | Int J STD AIDS2005，16，9： | 1 |
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