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| 1 | Rare Earths and Magnetic Refrigeration显示文摘Magnetic refrigeration is a revolutionary, efficient, environmentally friendly cooling technology, which is on the threshold of commercialization. The magnetic rare earth materials are utilized as the magnetic refrigerants in most cooling devices, and for many cooling application the Nd2Fe 14 B permanent magnets are employed as the source of the magnetic field. The status of the near room temperature magnetic cooling was reviewed. | Karl A Gschneidner Vitalij K Pecharsky | 2006 | Journal of Rare Earths2006，24，6： | 20 |
| 2 | Current position of ALPPS in the surgical landscape of CRLM treatment proposals显示文摘The Authors summarize problems,criticisms but also advantages and indications regarding the recent surgical proposal of associating liver partition and portal vein ligation(PVL)for staged hepatectomy(ALPPS)for the surgical management of colorectal liver metastases.Looking at published data,the technique,when compared with other traditional and well established methods such as PVL/portal vein embolisation(PVE),seems to give real advantages in terms of volumetric gain of future liver remnant.However,major concerns are raised in the literature and some questions remain unanswered,preliminary experiences seem to be promising.The method has been adopted all over the world over the last 2 years,even if oncological long-term results remain unknown,and benefit for patients is questionable.No prospective studies comparing traditional methods(PVE,PVL or classical 2 staged hepatectomy)with ALPPS are available to date.Technical reinterpretations of the original method were also proposed in order to enhance feasability and increase safety of the technique.More data about morbidity and mortality are also expected.The real role of ALPPS is,to date,still to be established.Large clinical studies,even if,for ethical reasons,in well selected cohorts of patients,are expected to better define the indications for this new surgical strategy. | Marcello Donati Gregor A Stavrou Karl J Oldhafer | 2013 | World Journal of Gastroenterology2013，19，39： | 16 |
| 3 | Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial显示文摘 | Roger Stupp Monika E Hegi Warren P Mason Martin J van den Bent Martin JB Taphoorn Robert C Janzer Samuel K Ludwin Anouk Allgeier Barbara Fisher Karl Belanger Peter Hau Alba A Brandes Johanna Gijtenbeek Christine Marosi Charles J Vecht Karima Mokhtari Piet | 2009 | Lancet Oncology2009，，5： | 4 |
| 4 | Post-cholecystectomy symptoms were caused by persistence of a functional gastrointestinal disorder显示文摘AIM:To classify gallstone disease as a basis for assessment of post-cholecystectomy symptoms.METHODS:One hundred and fifty three patients with a clinical and ultrasonographic diagnosis of gallstones filled out a structured questionnaire on abdominal pain symptoms and functional gastrointestinal disorder (FGID) before and at six months after cholecystectomy.Symptom frequency groups (SFG) were categorized according to frequency of pain attacks.According to certain pain characteristics in gallstone patients,a gallstone symptom score was accorded on a scale from one to ten.A visual analogue scale was used to quantify pain.Operative specimens were examined for size and magnitude of stone contents as well as presence of bacteria.Follow-up took place after six months with either a consultation or via a mailed questionnaire.Results were compared with those obtained pre-operatively to describe and analyze symptomatic outcome.RESULTS:SFG groups were categorized as severe (24.2%),moderate (38.6%) and mild (22.2%) attack frequency,and a chronic pain condition (15%).Pain was cured or improved in about 90% of patients and two-thirds of patients obtained complete symptom relief.Patients with the most frequent pain episodes were less likely to obtain symptom relief.FGID was present in 88% of patients pre-operatively and in 57% postoperatively (P=0.244).Those that became asymptomatic or improved with regard to pain also had most relief from FGID (P=0.001).No pre-operative FGID meant almost complete cure.CONCLUSION:Only one third of patients with FGID experienced postoperative relief,indicating that FGID was a dominant cause of post-cholecystectomy symptoms. | Malte Schmidt Karl Sφndenaa John A Dumot Steven Rosenblatt Trygve Hausken Maria Ramnefjell Gro Njφlstad Geir Egil Eide | 2012 | World Journal of Gastroenterology2012，18，12： | 4 |
| 5 | AN OVERVIEW OF CMIP5 AND THE EXPERIMENT DESIGN显示文摘 | Taylor Karl E Stouffer Ronald J Meehl Gerald A | 2012 | EN2012，，4： | 3 |
| 6 | The oral commensal Streptococcus mitis activates the aryl hydrocarbon receptor in human oral epithelial cells显示文摘Streptococcus mitis(S. mitis) is a pioneer commensal bacterial species colonizing many of the surfaces of the oral cavity in healthy individuals. Yet, not much information is available regarding its interaction with the host. We used examination of its transcriptional regulation in oral keratinocytes to elucidate some of its potential roles in the oral cavity. Transcription factor analysis of oral keratinocytes predicted S. mitis-mediated activation of aryl hydrocarbon receptor(Ah R). Activation and functionality of Ah R was confirmed through nuclear translocation determined by immunofluorescence microscopy and real-time polymerase chain reaction with reverse transcription analysis of CYP1A1, the hallmark gene for Ah R activation. Addition of Streptococcus mutans or Streptococcus gordonii did not induce CYP1A1 transcription in the keratinocyte cultures. Introduction of an Ah R-specific inhibitor revealed that S. mitis-mediated transcription of CXCL2 and CXCL8 was regulated by Ah R. Elevated levels of prostaglandin E2(enzyme-linked immunosorbent assay) in supernatants from S. mitis-treated oral epithelial cells were also attenuated by inhibition of Ah R activity. The observed Ah R-regulated activities point to a contribution of S. mitis in the regulation of inflammatory responses and thereby to wound healing in the oral cavity. The concept that the oral commensal microbiota can induce Ah R activation is important, also in view of the role that Ah R has in modulation of T-cell differentiation and as an anti-inflammatory factor in macrophages. | stian a engen gro h rørvik olav schreurs inger js blix karl schenck | 2017 | International Journal of Oral Science2017，9，3： | 2 |
| 7 | The reliability of investment property fair value estimates显示文摘 | J Richard Dietrich Mary S Harris Karl A Muller | 2001 | Journal of Accounting and Economics2001，，2： | 2 |
| 8 | Identification, synthesis and characterization of process related impurities of benidipine hydrochloride, stress-testing/stability studies and HPLC/UPLC method validations显示文摘Benidipine hydrochloride, used as an antihypertensive agent and long-acting calcium antagonist, is synthesized for commercial use as a drug substance in highly pure form. During the synthetic process development studies of benidipine, process related impurities were detected. These impurities were identi fi ed, synthesized and characterized and mechanisms of their formation were discussed in detail.After all standardization procedures, they were used as reference standards for analytical studies. In addition, a separate HPLC method was developed and validated for detection of residual 1-benzylpiperidin-3-ol(Ben-2), which is used during benidipine synthesis and controlled as a potential process related impurity. As complementary of this work, stress-testing studies of benidipine were carried out under speci fi ed conditions and a stability-indicating UPLC assay method was developed, validated and used during stability studies of benidipine. | Esen Bellur Atici Bekir Karl??a | 2015 | Journal of Pharmaceutical Analysis2015，5，4： | 2 |
| 9 | End-stage renal failure reduces central clearance and prolongs the elimination hald life of remifentanil 显示文摘 | Ashraf A Karl Oettl Von Klobucar F | 2002 | Can J Anaesth2002，49，4： | 1 |
| 10 | An introduction to trends in extreme weather and climate events: observations, socio-economic impacts, terrestrial ecological impacts, and model projections显示文摘 | Meehl G A Karl T Easterling D R | 2000 | Bulletin of the American Mathematical Society2000，81，3： | 1 |
| 11 | Die Tierwelt Deutschlands Urtiere Oder Protozoa (Friedrich Dahl)显示文摘 | Karl A | 1932 | Verlag von Gustav Fisher Jena1932，，： | 1 |
| 12 | Efflux of dietary flavonoid quercetin 4'-β-glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistanceassociated protein2显示文摘 | Richard A W Karl J R George E L | 2000 | J Pharm Exp Ther2000，294，3： | 1 |
| 13 | Human resource management in the knowledge economy 显示文摘 | Lengnick-Hall Karl K A | 2003 | Academy of Management Executive2003，，5： | 1 |
| 14 | Development of a quantitative method for the analysis of tobacco-specific nitrosa- mines in mainstream cigarette smoke using isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry 显示文摘 | Karl A W Nancy H F Fossett J E | 2005 | Analytical Chemistry2005，77，： | 1 |
| 15 | The use of a vegetation index for assessment of the urban heat island effect 显示文摘 | Gallo K P L Mcnab A Karl T R | 1993 | Int J Remote Serving1993，14，11： | 1 |
| 16 | Improved pharmacokinetics of recombinant bispecific antibody molecules by fusion to human serum albumin显示文摘 | Muller D Karle A Meissburger B | 2007 | J Biol Chem2007，282，12： | 1 |
| 17 | Gentamicin negatively influenced osteogenic function in vitro显示文摘 | Ince A Schütze N Karl N | 2007 | Int Orthop2007，31，： | 1 |
| 18 | Excitation-emission matrix fluorescence based determination of carbamate pesticides and polycyclic aromatic hydrocarbons显示文摘 | Renee D J Gary A C Karl S B | 1999 | Analytica Chimica Acta1999，，397： | 1 |
| 19 | Global variations in droughts and wetspells:1900~1995显示文摘 | Dai A Treaberth KE Karl TR | 1998 | Geophysical Research Letters1998，25，17： | 1 |
| 20 | Patients with mutations in NPHS2 (podocin) do not respond to standard steroid treatment of nephrotic syndrome 显示文摘 | Ruf RG Lichtenberger A Karle SM | 2004 | J Am Soc Nephrol2004，15，3： | 1 |
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