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| 1 | Apoptosis,antimicrobial and antioxidant activities of phytochemicals from Garcinia malaccensis Hk.f显示文摘Objective:To study the chemical constituents of stembark of Garcinia malaccenm(G.malaccenm) together with apoptotic.antimicrobial and antioxidant activities.Methods:Purification and structure elucidation were carried out by chromatographic and spectroscopic techniques, respectively.MTT and trypan blue exclusion methods were performed to study the cytotoxic activity.Antibacterial activity was conducted by dise diffusion and microdilulion methods, whereas antioxidant activities were done by ferric thiocyanate method and DPPH radical scavenging.Results:The phylochemical study led lo the isolation ofα,β-mangostin and cycloarl-24-en-3β-ol.α-Mangostin exhibited cytotoxic activity against HSC-3 cells with an IC50 of 0.33μM.β- andα-mangostin showed activity against K562 cells with IC50 of 0.40μM and 0.48μM,respectively,α-Mangostin was active against Gram-positive bacteria, Staphylococcus aureus(S.aureus) and Bacilus anthracis(B.anthmcis) with inhibition zone and MIC value of(19 mm;0.02S mg/mL) and(20 mm;0.013 mg/mL),respectively.In antioxidant assay,α-mangostin exhibited activity as an inhibitor of lipid peroxidation.Conclusions:G.malaccenm presenceα- andβ-mangostin and cycloart-24-en-3β-ol.β-Mangostin was found very active against H.SC-3 cells and KS62.The results suggest that mangoslins derivatives have the potential to inhibit the growth of cancer cells by inducing apoptosis.In addition,α-andβ-mangostin was found inhibit the growth of Cram-positive pathogenic bacteria and also showed the activity as an inhibitor of lipid peroxidation. | Muhammad Taher Deny Susanti Mohamad Fazlin Rezali Farah Syahidah Ahmad Zohri Solachuddin Jauhari Arief Ichwan Suhaib Ibrahim Alkhamaiseh Farediah Ahmad | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，2： | 5 |
| 2 | Weyl type theorem and the approximate point apectrum显示文摘 | Lahrouz M Zohry M | 2005 | Irish Math Soc Bulletin2005，55，： | 1 |
| 3 | Mycotoxin producing potential of some isolates of Aspergillus flavus and Eurotium groups from meat products显示文摘 | EI-Kady I EI-Maraghy S Zohri A N | 1994 | Microbiology Research1994，149，3： | 1 |
| 4 | Weyl type theorem and the approximate point apectrum显示文摘 | Lahrouz M Zohry M | 2005 | Irish Math Soc Bulletin2005，55，： | 1 |
| 5 | Polymeric nano particles:production,applicationsand advantage显示文摘 | Zohri M Gazori T Mirdamadi S | 2009 | The Internet Journal of Nanotechnology2009，3，1： | 1 |
| 6 | Characterization of Chitosan/Alginate Self-Assembled Nanoparticles as a Protein Carrier显示文摘 | Maryam Zohri Alireza Nomani Tarane Gazori Ismaeil Haririan SeyedSaeed Mirdamadi SeyedKazem Sadjadi MohammadReza Ehsani | 2011 | Journal of Dispersion Science and Technology2011，，4： | 1 |
| 7 | Indoor Surveillance of Airborne Fungi Contaminating Intensive Care Units and Operation Rooms in Assiut University Hospitals, Egypt显示文摘 | M. Bassam Aboul-Nasr Abdel-Naser A. Zohri Enas Mahmoud Amer | 2014 | Journal of Health Science2014，2，1： | 0 |
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