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| 1 | Research progress in artificial upwelling and its potential environmental effects显示文摘Artificial upwelling, as a geoengineering tool, has received worldwide attention because it may actualize ocean fertilization in a sustainable way, which could potentially alleviate the pressures on the fish stocks and human-driven climate change in the ocean. We reviewed the current knowledge on the development of an artificial upwelling system and its potential environmental effects. Special attention was given to the research progress on the air-lift concept artificial upwelling by Zhejiang University. The research on artificial upwelling over the past few decades has generated a range of devices that have been successfully applied in the field for months. Based on field experiments and the associated modeling results, part of them reported positive effects on increasing primary production and enhancing CO2 sequestration. However, as a significant disturbance to the environment, especially for large-scale applications, the uncertainties related to the potential effects on ecosystem remain unsolved. Zhejiang University has overcome the technical challenges in designing and fabricating a robust and high efficiency artificial upwelling device which has been examined in two field experiments in Qiandao Lake and one sea trial in the East China Sea. It was investigated that cold and hypoxic deep ocean water(DOW) could be uplifted to the euphotic layer, which could potentially change the nutrient distribution and adjust the N/P ratio. Both simulation and field experiments results confirmed that utilizing self-powered energy to inject compressed air to uplift DOW was a valid and efficient method. Therefore, further field-based research on artificial upwelling, especially for long-term field research is required to test the scientific hypothesis. | PAN YiWen FAN Wei ZHANG DaHai CHEN JiaWang HUANG HaoCai LIU ShuXia JIANG ZongPei DI YaNan TONG MengMeng CHEN Ying | 2016 | Science China Earth Sciences2016，59，2： | 3 |
| 2 | Reactive oxygen species mediate high glucose-induced plasminogen activator inhibitor-1 up-regulation in mesangial cells and in diabetic kidney显示文摘 | Eun Ah Lee Ji Yeon Seo Zongpei Jiang | 2005 | Kidney Int2005，67，： | 1 |
| 3 | Reactive oxygen species mediate TGF-β1-induced plasminogen activator inhibitor-1 upregulation in mesangial cells显示文摘 | Zongpei Jiang Ji Yeon Seo Hunjoo Ha Eun Ah Lee Yu Seun Kim Dong Cheol Han Soo Tack Uh Choon Sik Park Hi Bahl Lee | 2003 | Biochemical and Biophysical Research Communications2003，，4： | 1 |
| 4 | Current Situation and development of Small- and Special-motor industry in China显示文摘1. Introduction Small- and special-motors are those electrical motors havingsmall power ratings and special characteristics. As for 'small powerrating', in some countries it is defined as 70 watts and below. InChina, there is no explicit definition yet, but usually the A.C. andD.C. motors with power ratings up to a hundred watts and also thefractional horse power motors are included in the category of 'smallmotors'. These motors are extensively applied in the fields of mili- | Ding Shunnian Wang Zongpei CSEE Harbin Industrial University Jiang Huacheng | 1992 | Electricity1992，，2： | 0 |
| 5 | In Vivo Efficacy of Neuropeptide S on the Expression of Cytokines Indeced by Influenza A Virurs in Ducks显示文摘Neuropeptide S(NPS)is involved in severe pathological processes.Direct evidence showed NPS regulates the secretion of proinflammatory cytokines in pigs.This study investigated the effect of NPS on the secretion of inflammatory cytokines in ducks with H9N2 infection via intramuscular injection with NPS or NPS receptor(NPSR)antagonist.The ducks received 15 nM NPS or 10 nM NPSR antagonist in saline.Samples were collected to analyze the expression levels of IL-1β,IL-6,TNF-α,IFN-α,NPS,and the H9N2 gene NP by RT-PCR and real time RT-PCR;samples were fixed to observe the histopathological changes by hematoxylin-eosin staining.Serial blood samples were collected(every 30 min,starting 1 h before injections and lasting until 2 h after injections)to measure the serum levels of IL-1β,IL-6,TNF-α,and IFN-αby ELISA.Semiquantitative RT-PCR confirmed that the expression of NPS mRNA was increased in H9N2 infection group.Morphological data showed NPS treatment could reverse the pathological changes in the duck bursa induced by H9N2 infection.Both the results of real time quantitative RT-PCR and ELISA methods showed NPS and NPSR antagonist treatments could significantly regulate the expression of IFN-α,but not of IL-1β,IL-6 and TNF-α;meanwhile,the levels of increased IFN-α and decreased NP were further prompted by NPS,and NPSR antagonist revered.Conclusion,NPS is involved in the innate immunity response to H9N2 infection via the IFN-αpathway in ducks in vivo.These results indicate NPS affects the immune homeostasis and provides an alternative for anti-H9N2 drugs. | Ma Yijie Jiang Zongpei Zhang Tianhua Huang Cuiqin Yang Guihong | 2019 | Animal Husbandry and Feed Science2019，11，3： | 0 |
| 6 | Genome-wide identification of DNA-PKcs-associated RNAs by RIP-Seq显示文摘Dear Editor,The DNA-dependent protein kinase catalytic subunit(DNA-PKcs)forms a serine/threonine protein kinase complex with the Ku heterodimer(Ku70/Ku80)and plays an important role in the DNA damage response(DDR)and maintenance of genomic stability through nonhomologous end joining(NHEJ),wherein the Ku heterodimer recognizes and binds broken DNA ends,facilitating the recruitment and activation of DNA-PKcs.1 Activated DNA-PKcs phosphorylates and alters the function of factors that mediate NHEJ,including DNA-PKcs itself.2 In addition,DDR-independent roles of DNA-PKcs have been demonstrated.3 Studies further identified DNA-PKcs as a modulator of cancer-associated pathways distinct from DNA repair,including hypoxia,metabolism,the inflammatory response,and transcriptional regulation. | Zhiquan Song Ying Xie Zongpei Guo Yang Han Hua Guan Xiaodan Liu Teng Ma Ping-kun Zhou | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 0 |
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