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1GOECP/SEOR clinical guidelines on radiotherapy for malignant pleural mesothelioma显示文摘Malignant pleural mesothelioma(MPM)is a rare tumor with poor prognosis and rising incidence.Palliative care is common in MPM as radical treatment with curative intent is often not possible due to metastasis or extensive locoregional involvement.Numerous therapeutic advances have been made in recent years,including the use of less aggressive surgical techniques associated with lower morbidity and mortality(e.g.,pleurectomy/decortication),technological advancements in the field of radiotherapy(intensity-modulated radiotherapy,image-guided radiotherapy,stereotactic body radiotherapy,proton therapy),and developments in systemic therapies(chemotherapy and immunotherapy).These improvements have had as yet only a modest effect on local control and survival.Advances in the management of MPM and standardization of care are hampered by the evidence to date,limited by high heterogeneity among studies and small sample sizes.In this clinical guideline prepared by the oncological group for the study of lung cancer of the Spanish Society of Radiation Oncology,we review clinical,histologic,and therapeutic aspects of MPM,with a particular focus on all aspects relating to radiotherapy,including the current evidence base,associations with chemotherapy and surgery,treatment volumes and planning,technological advances,and reradiation.Javier Luna Andrea Bobo Joaquín José Cabrera-Rodriguez María Pagola Margarita Martín-Martín María Ángeles González Ruiz Miguel Montijano Aurora Rodríguez Lira Pelari-Mici Almudena Corbacho Marta Moreno Felipe Couñago 2021World Journal of Clinical Oncology2021,12,8:2
2Interactive effect of histamine and prostaglandin D2 on nasal allergic symptoms in rats 显示文摘RAHMAN A INOUE T AGO J 2007Eur J Pharmacol2007,554,23:1
3R andom ized,prospective,doub le-b lind com-parison of ahdominal and vaginal hysterectomy in wom en without uterovaginal prolapse 显示文摘M iskry T M agos A 2003A cta O bstet G ynecol Stand2003,82,4:1
4Selective reduction by isolation rearing of 5-HT1A receptor-mediated dopamine release in vivo in the frontal cortex of mice显示文摘Ago Y Sakaue M Baba A 2002Neurochem2002,83,2:1
5Postoperative radiotherapy in resected non-small cell lung cancer:The never-ending story显示文摘This manuscript collects in a joint and orderly manner the existing evidence at the present time about postoperative treatment with radiotherapy in non-small cell lung cancer.It also systematically reviews the current evidence,the international recommendations in the most relevant guidelines,the most controversial aspects in clinical and pathological staging,the specific technical aspects of radiotherapy treatment,and also collects all the potential risk factors that have been postulated as significant in the prognosis of these patients,evaluating the possibility of segmenting a particularly sensitive subpopulation with a high risk of relapse on which an adjuvant treatment with radiotherapy could have an impact on their clinical evolution.Finally,currently active trials that aspire to provide more evidence on this topic are reviewed.Javier Serrano Patricia Calvo Crespo Begoña Taboada Ana Alvarez Gonzalez Rafael Garcia García Antonio Gomez Caamaño Juan Carlos Trujillo Reyes Xabier Mielgo-Rubio Felipe Couñago 2021World Journal of Clinical Oncology2021,12,10:1
6Detection of the Presence of Refined Hazelnut Oil inRefined Olive Oil by Fluorescence Spectroscopy 显示文摘Say ago A Garcia-Gonzalez D L Morales M T 2007J Agric Food Chem2007,55,:1
7Recent advances and new insights in the management of early-stage epidermal growth factor receptor-mutated non-small-cell lung cancer显示文摘Patients with early-stage non-small-cell lung cancer(NSCLC)are candidates for curative surgery;however,despite multiple advances in lung cancer management,recurrence rates remain high.Adjuvant chemotherapy has been demonstrated to significantly prolong overall survival(OS),but this benefit is modest and there is an urgent need for effective new therapies to provide a cure for more patients.The high efficacy of tyrosine kinase inhibitors(TKIs)against epidermal growth factor receptor-mutated(EGFR)in patients with advanced EGFR-mutated NSCLC has led to the evaluation of these agents in early stages of the disease.Multiple clinical trials have evaluated the safety and efficacy of EGFR TKIs as an adjuvant treatment,in patients with resected EGFR-mutated NSCLC,and shown that they significantly prolong disease-free survival(DFS),but this benefit does not translate to OS.Recently,an interim analysis of the ADAURA trial demonstrated that,surprisingly,osimertinib improved DFS.This led to the study being stopped early,leaving many unanswered questions about its potential effect on OS and its incorporation as a standard adjuvant treatment in this patient subgroup.These targeted agents are also being evaluated in locally-advanced disease,with promising results,although prospective studies with larger sample sizes are needed to confirm these results.In this article,we review the most relevant studies on the role of EGFR TKIs in the management of early-stage EGFR-mutated NSCLC.Miguel J Sotelo Jose Luis García Cesar Torres-Mattos Héctor Milián Carlos Carracedo María Angeles González-Ruiz Xabier Mielgo-Rubio Juan Carlos Trujillo-Reyes Felipe Couñago 2021World Journal of Clinical Oncology2021,12,10:1
8Level of circulating endothelial cells and expression of nu- clear factor kappa beta of human's peripheral blood mononuclear cells in subjects with certain conditions 显示文摘Wihastuti TA Sargowo D Agoes A 2014Acta Med Indones2014,46,1:1
9The effects of low-level laser therapy on palatal mucoperiosteal wound healing and oxidative stress status in experimental diabetic rats 显示文摘Firat ET Dag AGO nay A 2013Photomed Laser Surg2013,31,7:1
10mGlu2/3 and mGlu5 receptors: potential targets for novel antidepressants 显示文摘Chaki S Ago Y Palueha-Paniewiera A etal 2013Neuropharmacology2013,66,:1
11Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus 显示文摘Ago H Adachi T Yoshida A 1999Structure with Folding and Design1999,7,11:1
12control of preview systems显示文摘Agoes A Moelja Gjerrit Meinsma 2006Automatica2006,42,6:1
13GOECP/SEOR radiotherapy guidelines for small-cell lung cancer显示文摘Small cell lung cancer(SCLC)accounts for approximately 20%of all lung cancers.The main treatment is chemotherapy(Ch).However,the addition of radiotherapy significantly improves overall survival(OS)in patients with non-metastatic SCLC and in those with metastatic SCLC who respond to Ch.Prophylactic cranial irradiation reduces the risk of brain metastases and improves OS in both metastatic and non-metastatic patients.The 5-year OS rate in patients with limited-stage disease(non-metastatic)is slightly higher than 30%,but less than 5%in patients with extensive-stage disease(metastatic).The present clinical guidelines were developed by Spanish radiation oncologists on behalf of the Oncologic Group for the Study of Lung Cancer/Spanish Society of Radiation Oncology to provide a current review of the diagnosis,planning,and treatment of SCLC.These guidelines emphasise treatment fields,radiation techniques,fractionation,concomitant treatment,and the optimal timing of Ch and radiotherapy.Finally,we discuss the main indications for reirradiation in local recurrence.Felipe Couñago Carolina de la Pinta Susana Gonzalo Castalia Fernández Piedad Almendros Patricia Calvo Begoña Taboada Antonio Gómez-Caamaño JoséLuis López Guerra Marisa Chust JoséAntonio GonzálezFerreira AnaÁlvarez González Francesc Casas 2021World Journal of Clinical Oncology2021,12,3:1
14Morning blood pres- sure is useful for detection of left ventrioular hyper- trophy in hemodialysis patients显示文摘Ago R Nakashima A Naito T 2012Clin Exp Nephrol2012,16,:1
15Identification of tissue specificmicroRNAs from mouse显示文摘I agos M Rauhut R Yalcin A 2002Curr Bioi2002,12,:1
16Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus显示文摘Ago H Adachi T Yoshida A 0,,11:1
17Effects of osemozotan,ritanserin and azasetron on cocaine-induced behavioral sensitization in mice显示文摘Ago Y Nakamura S Hayashi A 2006Pharmacol Biochem Behav2006,85,1:1
18Physical activity, screen time and obesity status in a nationally representative sample of Maltese youth with international comparisons 显示文摘DECELIS A ]AGO R FOX K R 2014BMC Public Health2014,14,14:1
19Preferences for paper bedding material of the laboratory mice显示文摘Ago A Gonda T Takechi M 2002Exp Anim2002,51,2:1
20Preferences for paper bedding material of the laboratory mice显示文摘Ago A Gonda T Takechi M 2002Exp Anim2002,51,2:1
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