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| 1 | Hepatocellular carcinoma in central Sydney :a 10yearreview of patients seen in a medical oncology department显示文摘AIM To report a single Australian oncology unit′s experience with the management of patients with hepatocellular carcinoma (HCC), in the context of a literature review of the current management issues. METHODS Retrospective case record review of 76 patients with diagnosis of HCC referred to the unit between 1984 and 1995. RESULTS Sixty three patients had adequate records for analysis. Thirty six (56%) were migrants with half from Southeast Asia. Twenty four patients had a documented viral aetiology. Nine (14%) of 51 patients with pathological confirmation of HCC had normal alpha fetoprotein levels. Median survival of the 20 patients managed palliatively was 5 weeks compared to 16 weeks for the cohort overall. Surgery in 16 patients rendered all initially disease free with a median survival of 88 weeks. Chemoembolisation induced tumor responses in 5 of the 11 patients so treated. Systemic chemotherapy and tamoxifen treatment caused tumor response in two of 12 and one of 25 respectively. CONCLUSION Prolonged survival of patients with HCC depends on early detection of small tumors suitable for surgical resection. Other active treatments are palliative in intent and have limited success. In addition to tumor response and survival duration, the toxicities of therapies and the overall quality of life of patients need to be considered as important outcomes. Viral hepatitis prevention and screening of individuals at risk are strategies that are important for HCC management in communities where the disease is endemic. | Desmond Yip 1, Michael Findlay 2, Michael Boyer 1 and Martin H. Tattersall 3 | 1999 | World Journal of Gastroenterology1999，5，6： | 17 |
| 2 | LINEAR AND HYPERBRANCHED POLYMERS WITH HIGH THERMAL STABILITY AND LUMINESCENCE EFFICIENCY显示文摘New acetylene monomers, 6-{[(1-naphthylethynyl-4-phenyl)carbonyl]oxy}-l-phenyl-l-hexyne (1), 2,5-diethynylthiophene (3), and 4,4′-diethynylbiphenyl (6) were synthesized. Homopolymerization of 1 and copolycyclotrimerizations of 3and 6 with 1-heptyne and l-octyne have been achieved with WCI6- and TaC15-Ph4Sn catalysts, respectively, giving soluble linear disubstituted polyacetylene (2) and hyperbranched polyarylenes (5 and 8) with high molecular weights (up to 1.2 ×105) in high yields (upto 98%). The structures and properties of the polymers are characterized and evaluated by IR, NMR,TGA, UV, photoluminescence (PL), and electroluminescence (EL) analyses. All the polymers possess high thermal stability and emit strong blue light upon photoexcitation. The intensity of the emitted light is greater than that of poly(1-phenyl-1-octyne), a well-known highly luminescent disubstituted polyacetylene. Little aggregation-induced red shift in the PL was observed in the thin films of the polymers. By constructing a multi-layer EL device, high EL quantum yield (0.18%) has been achieved in 2, which are the best results for substituted polyacetylenes attainable so far. | Jacky Wing Yip Lam Jing-dong Luo Han Peng Zhi-liang Xie Kai-tian Xue Yu-ping Dong Lin Cheng Cheng-feng Qiu Hoi Sing Kwok Ben-zhong Tang Departments of Chemistry and Electrical & Electronic Engineering Hong Kong University of Science & Technology Clear Water Bay, Kowloon, Hong Kong China | 2001 | Chinese Journal of Polymer Science2001，19，6： | 2 |
| 3 | Global account management:The new frontier in relationship management显示文摘 | Yip G S and Madsen T L | 1996 | International Marketing Review1996，13，3： | 1 |
| 4 | On modeling claim frequency data in general insurance with extra zeros 显示文摘 | Karen C H Yip Kelvin K W and Yau | 2005 | Insurance: Mathematics and Economics2005，，36： | 1 |
| 5 | Statistical evidence on global account management programs显示文摘 | Montgomery D B and Yip G S | 1999 | Thexis1999，，4： | 1 |
| 6 | Non-Evidence-Based Policy:How Effective is China’s New Cooperative Medical Scheme in Reducing Medical Impoverishment?显示文摘 | Yip W and W C Hsiao | 2009 | Social Science and Medicine2009，2，： | 1 |
| 7 | Dynamic surface control for a class of nonlinear systems显示文摘 | Swaroop D Hedrick J K Yip P P and Gerdes J C | 2000 | IEEE Transactions on Automatic Control2000，45，10： | 1 |
| 8 | Experiences and challenges in industrialized countries显示文摘 | Usha Ramakrishnan and Rap Yip | 2002 | J Nutr2002，132，： | 1 |
| 9 | Dynamic surface control for a class of nonlinear systems显示文摘 | D Swaroop J K Hedrick P P Yip and J C Gerdes | 2000 | IEEE Transactions on Automatic Control2000，45，10： | 1 |
| 10 | The relative influence ofcountry conditions, industry structure, and business strategyon MNC subsidiary performance 显示文摘 | Christmann P Day D and Yip GS | 1999 | Journal of InternationalManagement1999，5，： | 1 |
| 11 | Perforated wall breakwater with internal horizontal plate显示文摘 | YIP T L and CHWANG A T | 2000 | Journal of Engineering Mechanics ASCE2000，126，5： | 1 |
| 12 | Global account management:The new frontier in relationship marketing显示文摘 | Yip G S and Madsen T L | 1996 | International Marketing Re-view1996，13，8： | 1 |
| 13 | An Empirical Evaluation of Government Scholarship Policy in Malaysia 显示文摘 | Ozay Mehmet and Yip Yat Hoong | 1985 | Higher Education1985，14，2： | 1 |
| 14 | Heparanase,hyaluronan,and CD44 in cancers:a breast carcinoma perspective显示文摘 | C(o)tte M and Yip GW | 2006 | Cancer Res2006，66，10： | 1 |
| 15 | Modification of Hough Transform for Circles and Ellipses Detection Using a 2-Dimensional Array显示文摘 | Yip R K K Tam P K S and Leung D N K | 1992 | Pattern Recog1992，25，： | 1 |
| 16 | A fast optimization transfer algorithm for image inpainting in wavelet domains显示文摘 | Chan R Wen Y and Yip A | 2009 | [EEE Transactions on Image Processing2009，18，7： | 1 |
| 17 | A primal-dual method for total variation based wavelet domain inpainting显示文摘 | Wen Y Chan R and Yip A | 2012 | IEEE Transactions on Image Processing2012，21，1： | 1 |
| 18 | Statistical evidence on global account management programs显示文摘 | Montgomery D B and Yip G S | 1999 | Thexis1999，16，4： | 1 |
| 19 | The challenge of global customer management: Companies need to respond to rising customer demands for global relationships显示文摘 | Montgomery D B and Yip G S | 2000 | Marketing Management2000，9，4： | 1 |
| 20 | Modification of Hough transform for circles and ellipses detection using a 2-dimensional array显示文摘 | YIP R K K TIM P K S and LEU NG D N K | 1992 | Pattern Recognit1992，25，9： | 1 |
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