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| 1 | Laparoscopic vs open approach to resection of hepatocellular carcinoma in patients with known cirrhosis:Systematic review and meta-analysis显示文摘AIM: To review the currently available literature comparing laparoscopic to open resection of hepatocellular carcinoma(HCC) in patients with known liver cirrhosis.METHODS: A literature search of MEDLINE, EMBASE, and Cochrane databases was conducted. The search terms used included(laparoscopic OR laparoscopy) AND(hepatic or liver) AND(surgery or resection) AND 'hepatocellular carcinoma' AND(cirrhosis or cirrhotic). Furthermore, to widen the search, we also used the 'related articles' section. Studies reporting a comparison of outcomes and methods of open vs laparoscopic hepatic resection for HCC in patients with liver cirrhosis were included. Meta-analysis of results was performed using a random effects model to compute relative risk(RR) and for dichotomous variablesand standard mean differences(SMD) for continuous variables.RESULTS: A total of 420 patients from 4 cohort studies were included in final analysis. Patients undergoing laparoscopic procedures had statistically less blood loss compared to the open cohort, SMD of-1.01(95%CI:-1.23-0.79), P < 0.001, with a reduced risk of transfusion, RR = 0.19(95%CI: 0.09-0.38), P < 0.001. A wider clearance at tumour resection margins was achieved following a laparoscopic approach, SMD of 0.34(95%CI: 0.08-0.60), P = 0.011. No significant difference was noted between laparoscopic and open resection operative times, SMD of-0.15(95%CI: 0.35-0.05), P = 0.142. The overall RR of suffering from postoperative morbidity is 0.25 in favour of the open surgery cohort(95%CI: 0.17-0.37), P < 0.001. Patients under-going laparoscopic surgery had significantly shorter length of stays in hospital compared to the open cohort, SMD of-0.53(95%CI:-0.73 to-0.32), P < 0.001.CONCLUSION: This review suggests that laparoscopic resection of hepatocellular carcinoma in patients with cirrhosis is safe and may provide improved patient outcomes when compared to the open technique. | Ahmed Twaij Philip H Pucher Mikael H Sodergren Tamara Gall Ara Darzi Long R Jiao | 2014 | World Journal of Gastroenterology2014，20，25： | 16 |
| 2 | 左心房结构和功能改变可早期预测无症状高血压患者左心室功能不全显示文摘该研究旨在探索无症状高血压患者左心房结构和功能改变与左心室功能不全之间的关系。入选左心室射血分数(1eft ventricular ejection fraction,LVEF)≥60%的无症状高血压患者126例。应用常规脉冲组织多普勒及二维斑点追踪超声心动图(two-dimensional speckle—tracking echocardiography,2DSTE)检测和分析左心房结构与功能改变的独立影响因素。 | Miyoshi H Oishi Y Mizuguchi Y Iuchi A Nagase N Ara N Oki T 刘莉 叶鹏 | 2013 | 中华高血压杂志2013，21，5： | 2 |
| 3 | Pentoxifylline improves blood flow to both testes in testicular torsion 显示文摘 | Savas C Dindar H Aras T | 2002 | Int Urol Nephrol2002，33，1： | 1 |
| 4 | Immunoglobulin G4-related lung disease accompanied by organizing pneumonia 显示文摘 | Suzuki H Wstanabe M Ara T | 2013 | Intern Med2013，52，18： | 1 |
| 5 | Immunoglobulin G4-related lung disease accompanied by organizing pneumonia显示文摘 | Suzuki H Watanabe M Ara T | 2013 | Intern Med2013，52，18： | 1 |
| 6 | Status of engineering design of liquid lithium target in IFMIFEVEDA显示文摘 | Nakamura H Agostini P Ara K | 2009 | Fusion Engineering and Design2009，84，25： | 1 |
| 7 | Plasma homocysteine levels in living kidney donors before and after uninephrectomy显示文摘 | Tsai MY Aras O Sozen H | 2004 | J Lab Clin Med2004，143，： | 1 |
| 8 | Immunoglobulin G4-related lung disease accompanied by organizing pneumonia显示文摘 | Suzuki H Watanabe M Ara T | 2013 | Intern Med2013，52，： | 1 |
| 9 | Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment显示文摘 | Santos L H M L M Araújo A N Fachini A Pena A Delerue-Matos C Montenegro M C B S M | | 0，，： | 1 |
| 10 | Latest design of liquid lithium target in IFMIF显示文摘 | Nakamura H Agostini P Ara K | 2008 | Fusion Engineering and Design2008，83，10： | 1 |
| 11 | Ecotoxicological aspectsrelated to the presence of pharmaceuticals in the aquatic environment显示文摘 | SANTOS L H ARAJO A N FACHINI A | 2010 | J Hazard Mater2010，175，13： | 1 |
| 12 | Competitive fa- cility location problem with attractiveness adjustment of the follower: a bilevel programming model and its so- lution 显示文摘 | Kucuikaydin H Aras N Altlnel I K | 2011 | European Journal of Operational Research2011，208，3： | 1 |
| 13 | Turkey and Eurasia:Frontiers of a New Geographic Imagination显示文摘 | Aras B Fidan H | | 0，，01： | 1 |
| 14 | Prostate cancer: canmultiparametric MR imaging help identify patients who arecandidates for active surveillance-显示文摘 | Turkbey B Mani H Aras O | 2013 | Radiology2013，268，1： | 1 |
| 15 | Optical coherence tomography for evaluation of anatomical changes in the cornea after laser in situ keratomileusis显示文摘 | Usttmdag C Bahcecioglu H Ozdamar A Aras C Yildirim R Ozkan S | 2000 | J Cataract Refract Surg2000，26，10： | 1 |
| 16 | Phase II study of a combination of irinotecan and S-1 in patien ts with advanced gastric cancer(OGSG0002)显示文摘 | U edo N Narah ara H Ishihara R | 2007 | Oncology2007，73，12： | 1 |
| 17 | Asian dust:seasonal transport to the Hawaiian Islands显示文摘 | Parrington J R Zoller W H Aras N K | 1983 | Science (Washington DC)1983，246，： | 1 |
| 18 | A hybrid tabu search heuristic for a bilevel competitive facility location model显示文摘 | Kü?ükaydin H Aras N Altinel I K | 2010 | Hybrid Metaheuristics2010，6373，： | 1 |
| 19 | Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors显示文摘 | Dong Wook Han Natalia Tapia Andreas Hermann Kathrin Hemmer Susanne H?ing Marcos J. Araúzo-Bravo Holm Zaehres Guangming Wu Stefan Frank S?ren Moritz Boris Greber Ji Hun Yang Hoon Taek Lee Jens C. Schwamborn Alexander Storch Hans R. Sch?ler | 2012 | Cell Stem Cell2012，，4： | 1 |
| 20 | Potassium-modified Mg(NH2)2/2Li H system for hydrogen storage显示文摘 | Wang J H Liu T Wu G T Li W Liu Y F Moysés Araújo C Scheicher R H Blomqvist A Ahuja R Xiong Z T Yang P Gao M X Pan H G Chen P | 2009 | Angewandte Chemie International Edition2009，48，： | 1 |
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