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| 1 | 生理过度觉醒相关失眠增加高血压风险显示文摘先前的研究显示,失眠和客观睡眠时间过短与高血压风险增加相关,并推测其潜在的机制是生理过度觉醒。在该研究中,研究者通过多次睡眠潜伏期试验(multiplesleeplatencytest,MSLT)——一种睡眠/觉醒的标准测试,探讨与生理过度觉醒相关的失眠是否与高血压风险增加相关。 | Li Y Vgontzas AN Fernandez-Mendoza J Bixler EO Sun Y Zhou J Ren R Li T Tang X 戴伦 练桂丽 | 2015 | 中华高血压杂志2015，23，2： | 2 |
| 2 | Insensitivity of NMRI mice to selective serotonin reuptake inhibitors in the tail suspension test can be reversed by co-treatment with 5- hydroxytryptophan 显示文摘 | Jacobsen JP Nielsen EO Hummel R | 2008 | Psychopharmacology (Berl)2008，199，2： | 1 |
| 3 | Development of a rapid and specific assay for detection of busulfan in human plasma by high-performance liquid chromatography/elect rospray ionization tandem mass spectrometry显示文摘 | Dos Reis EO Vianna-Jorge R Suarez-Kurtz G | | 0，，12： | 1 |
| 4 | Perioperative complications and risk factors of percutaneous nephrolithotomy 显示文摘 | VORRAKITPOKATORN P PERMTONGCHUCHAI K R - AKSAMANI EO | 2006 | J Med Assoc Thai2006，89，6： | 1 |
| 5 | S-parameter based IC interconnect transmission line characterization显示文摘 | EISENSTADT W R Eo Y | 1992 | IEEE Transactions on Components Hybrid Manufacturing Technology1992，15，： | 1 |
| 6 | IL-6 and IL-8 levels in GCF of the teeth supporting fixed partial denture显示文摘 | Erdemir EO Baran I Nalcaci R | 2010 | Oral Dis?2010，16，1： | 1 |
| 7 | Effects of tai chi exercise on pain, balance, muscle strength, and perceived difficulties in physical functioning in older women with osteoarthritis: a randomized clinical trial显示文摘 | Song R Lee EO Lam P | 2003 | The Journal of Rheumatolo- gy2003，30，9： | 1 |
| 8 | Blockade of lymphocyte chemotaxis in visceral graft-versus-host disease显示文摘 | Reshef R Luger SM Hexner EO | 2012 | N Engl J Med2012，367，2： | 1 |
| 9 | Effects of a Sun-style Tai Chi exercise on arthritic symptoms, motivation and the per- formance of health behaviors in women with osteoarthritis 显示文摘 | Song R Lee EO Lam P | 2007 | Taehan Kanho Hakhoe Chi2007，37，2： | 1 |
| 10 | Operative versus non-opera-tive management following Rockwood gradeⅢacromioclavicularseparation:A meta-analysis of the current evidence base显示文摘 | Smith TO Chester R Pearse EO | 2011 | Journalof Orthopaedics and Traumatology2011，12，1： | 1 |
| 11 | Effects of tai chi exercise on pain,balance,muscle strength,and perceived difficulties in physical functioning in older women with osteoarthritis:a randomized clinical trial显示文摘 | Song R Lee EO Lam P Bae SC | | 0，，： | 1 |
| 12 | Adhesives bonded to erbium:yttrium-aluminum-garnet laser-irradiated dentin:transmission electron microscopy,scanning electron microscopy and tensile bond strength analyses显示文摘 | Andreia C Bastos R Marcella EO | 2010 | Lasers Med Sci2010，25，： | 1 |
| 13 | Aggression and seclusion on acute psychiatric wards:effect of short-term risk assessment显示文摘 | van de Sande R Nijman HLI Noorthoorn EO | 2011 | Br J Psychiatry2011，199，6： | 1 |
| 14 | Operative versus non- operative management following Rockwood grade III acro- mioclavicular separation: a meta-analysis of the current ev- idence base 显示文摘 | Smith TO Chester R Pearse EO | 2011 | J Orthop Traumatol2011，12，1： | 1 |
| 15 | A new on-chip interconnect crosstalk model and experimental verification for CMOS VLSI circuit design显示文摘 | Yungseon Eo Eisenstadt Wiliam R Ju Young Jeong | 2000 | IEEE Transactions on Electron Devices2000，47，1： | 1 |
| 16 | Generalized coupled interconnect transfer function and high-speed signal simulation显示文摘 | Eo Y Eisenstadt W R | 1995 | IEEE Trans Microwave Theory Tech1995，43，5： | 1 |
| 17 | Probiotics in the critically ill : a systemtic review of therandomized trial evidence 显示文摘 | PETROF EO DHALIWAL R MANZANARES W | 2012 | Crit Care Med2012，40，12： | 1 |
| 18 | In vitro-in vivo studies on anti-trypanosomal potentials of Zapoteca portoricensis显示文摘Objective:Aqueous extracts of Zapoteca portoricensis are used traditionally as antidiarrhea agent and in the treatment of diverse gastrointestinal disorders here in Nigeria specifically,the southern part.Similarly,the aqueous extract of the plant is also used traditionally as anticonvulsant,antispasmodic and in the treatment of tonsillitis.Recently too,the anti-inflammatory and antimicrobial activities of the methanol extracts of the root of Zapoteca portoricensis was reported.In this research,we are set to investigate the trypanocidal activity of Zapoteca portoricensis.Methods:The methanol extract of the root of Zapoteca portoricensis was investigated for both in vitro and in vivo trypanocidal activity following established models.In summary,phytochemical analysis was carried out on both the crude powdered root and on the methanol extract following standard procedures. The oral acute toxicity test(LD50 ) of the crude methanol extract was determined according to the method described by Lorke(1983).Albino mice(17g-21g) of either sex were used.The methanol extract was suspended in 3%v/v tween 85 and administered orally at doses of 10 mg/kg,100 mg/kg and 1 000 mg/kg to three groups of mice(n = 3 ).The animals were observed for 24 hours.Based on the result obtained in this initial test,doses of 4 mg/kg,6 mg/kg,and 8 mg/kg were administered to three different mice.The LD50 was calculated as the geometric mean of the lowest dose killing a mouse and the highest dose showing no death.The invivo /in-vitro antitrypanosomal evaluations were carried out in experimental animals and tissue cell culture respectively. Results:The result of the in vitro studies shows the inhibitive concentration-50(IC-50) against Trypanosoma brucei rhodesiense(T.b.rhodesiense) to be 0.372 mg/kg,while the control drug melarsoprol was 0.006 mg/kg.On Trypanosoma brucei brucei(T.cruzi),the IC-50 is 6.42 mg/kg against 0.87 of the reference drug Benznidazole.The cytotoxicity on L-6 cells exhibited an IC-50 of 0.039 6 mg/kg against the reference drug,podophyllotoxin of 0.01 mg/kg.However,the in vivo study shows that the extract,at the administered doses,could not exhibit appreciable reduction of parasitemia and hence resulted to the death of test animals. Conclusion:The present data suggests that Zapoteca portoricensis could yield useful leads for the development of potentially potent antitrypanocides. | Nwodo NJ Omeje EO Bran R | 2009 | Asian Pacific Journal of Tropical Medicine2009，2，1： | 1 |
| 19 | Nickel zinc ferrites prepared by the citrate precursor method 显示文摘 | Sil eo E E Rotelo R Jacobo S E | 2002 | Physica B2002，320，： | 1 |
| 20 | A randomized study of the effects of t'ai chi on muscle strength, bone mineral density, and fear of falling in women with osteoarthritis显示文摘 | Song R Roberts BL Lee EO | 2010 | Journal of Alternative and Complementary Medicine2010，16，3： | 1 |
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