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| 1 | Prognostic value of red blood cell distribution width for severe acute pancreatitis显示文摘BACKGROUND Severe acute pancreatitis(SAP)is a common condition in the intensive care unit(ICU)and has a high mortality.Early evaluation of the severity and prognosis is very important for SAP therapy.Recently,red blood cell distribution(RDW)was associated with mortality of sepsis patients and could be used as a predictor of prognosis.Similarly,RDW may be associated with the prognosis of SAP patients and be used as a prognostic indicator for SAP patients.AIM To investigate the prognostic value of RDW for SAP patients.METHODS We retrospectively enrolled SAP patients admitted to the ICU of the First Affiliated Hospital of China Medical University from June 2015 to June 2017.According to the prognosis at 90 d,SAP patients were divided into a survival group and a non-survival group.RDW was extracted from a routine blood test.Demographic parameters and RDW were recorded and compared between the two groups.The receiver operator characteristic(ROC)curve was constructed and Cox regression analysis was performed to investigate the prognostic value of RDW for SAP patients.RESULTS In this retrospective cohort study,42 SAP patients were enrolled,of whom 22 survived(survival group)and 20 died(non-survival group).The baseline parameters were comparable between the two groups.The coefficient of variation of RDW(RDW-CV),standard deviation of RDW(RDW-SD),Acute Physiology and Chronic Health Evaluation II(APACHE II)score,and Sequential Organ Failure Assessment(SOFA)score were significantly higher in the non-survival group than in the survival group(P<0.05).The RDW-CV and RDW-SD were significantly correlated with the APACHE II score and SOFA score,respectively.The areas under the ROC curves(AUCs)of RDW-CV and RDW-SD were all greater than those of the APACHE II score and SOFA score,among which,the AUC of RDW-SD was the greatest.The results demonstrated that RDW had better prognostic value for predicting the mortality of SAP patients.When the RDW-SD was greater than 45.5,the sensitivity for predicting prognosis was 77.8%and the specificity was 70.8%.Both RDW-CV and RDW-SD could be used as independent risk factors to predict the mortality of SAP patients in multivariate logistic regression analysis and univariate Cox proportional hazards regression analysis,similar to the APACHE II and SOFA scores.CONCLUSION The RDW is greater in the non-surviving SAP patients than in the surviving patients.RDW is significantly correlated with the APACHE II and SOFA scores.RDW has better prognostic value for SAP patients than the APACHE II and SOFA scores and could easily be used by clinicians for the treatment of SAP patients. | Fang-Xiao Zhang Zhi-Liang Li Zhi-Dan Zhang Xiao-Chun Ma | 2019 | World Journal of Gastroenterology2019,25,32: | 50 |
| 2 | Recovery of Iron From High-Iron Red Mud by Reduction Roasting With Adding Sodium Salt显示文摘Red mud is the waste generated during aluminum production from bauxite, containing lots of iron and other valuable metals. In order to recover iron from red mud, the technology of adding sodium carbonate-reduction roasting-magnetic separation to treat high-iron red mud was developed. The effects of sodium carbonate dosage, reduction temperature and reduction time on the qualities of final product and the phase transformations in reduction process were discussed in detail. The results showed that the final product (mass percent), assaying Fe of 90.87% and Al2O3 of 0.95% and metallization degree of 94.28% was obtained at an overall iron recovery of 95.76% under the following conditions of adding 8% sodium carbonate, reduction roasting at 1 050 ℃ for 80 min and finally magnetic separation of the reduced pellets by grinding up to 90% passing 0.074 mm at magnetic field intensity of 0.08 T. The XRD (X-ray diffraction) results indicated that the iron oxides were transformed into metallic iron. Most of aluminum mineral and silica mineral reacted with sodium carbonate during the reduction roasting and formed nonmagnetic materials. | ZHU De-qing, CHUN Tie-jun, PAN Jian, HE Zhen (School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, Hunan, China) | 2012 | Journal of Iron and Steel Research(International)2012,19,8: | 38 |
| 3 | Red blood cell distribution width in heart failure: A narrative review显示文摘The red blood cell distribution width(RDW) is a simple, rapid, inexpensive and straightforward hematological parameter, reflecting the degree of anisocytosis in vivo. The currently available scientific evidence suggests that RDW assessment not only predicts the risk of adverse outcomes(cardiovascular and all-cause mortality, hospitalization for acute decompensation or worsened left ventricular function) in patients with acute and chronic heart failure(HF), but is also a significant and independent predictor of developing HF in patients free of this condition. Regarding the biological interplay between impaired hematopoiesis and cardiac dysfunction, many of the different conditions associated with increased heterogeneity of erythrocyte volume(i.e., ageing, inflammation, oxidative stress, nutritional deficiencies and impaired renal function), may be concomitantly present in patients with HF, whilst anisocytosis may also directly contribute to the development and worsening of HF. In conclusion, the longitudinal assessment of RDW changes over time may be considered an efficient measure to help predicting the risk of both development and progression of HF. | Giuseppe Lippi Gianni Turcato Gianfranco Cervellin Fabian Sanchis-Gomar | 2018 | World Journal of Cardiology2018,10,2: | 37 |
| 4 | Red cell distribution width to platelet ratio: New and promising prognostic marker in acute pancreatitis显示文摘AIM: To evaluate the accuracy of red cell distribution width(RDW) to platelet ratio(RPR) to predict in-hospital mortality in acute pancreatitis(AP).METHODS: Between January 2010 and June 2012, 102 patients with AP were recruited to the study. In this retrospective cohort study, for all subjects, demographic data on hospital admission, AP etiology, comorbid diseases, organ failure assessment, laboratory parameters and length of hospital stay were examined. Additionally, we used a non-invasive prediction method in addition to the RPR to evaluate the disease severity. Multivariate logistic regression analyses were used to evaluate the impact of RPR on hospital admission to predict mortality.RESULTS:The male-female ratio(59/43)was 1.37with a median age of 56.5 years(17-89 years).In both univariate and multivariate analyses,RDW and RPR were presented as independent and significant variables on admission to predict mortality.The RPR obtained on hospital admission was persistently higher amongnon-survivors than among survivors(P<0.0001).The median RPR was 0.000087 in the non-survivor group and 0.000058 in the survivor group.RPR with a cutoff value of 0.000067 presented an area under the curve of 0.783(95%CI:0.688-0.878)in receiver operating characteristic curves and could predict the mortality of approximately 80%of the patients. | Erdin etinkaya Kazim Senol Baris Saylam Mesut Tez | 2014 | World Journal of Gastroenterology2014,20,39: | 38 |
| 5 | Magnetostratigraphy and palaeoclimate of Red Clay sequences from Chinese Loess Plateau显示文摘Two Red Clay profiles near Xi’ an and Xifeng were investigated in an attempt to determine magne-tostratigraphic and palaeoclimatic records. The results show that aeolian dust accumulation and the related East Asia palaeomonsoon system had begun by 6.5 Ma, and it is deduced that the Tibetan Plateau had reached a significant elevation at that time. The late Tertiary palaeoclimatic history of the Red Clay as reflected by magnetic susceptibility is reconstructed during the period of 6.5-2.5 Ma. Stepwise increase in susceptibility of aeolian dust accumulation appears to have a close correlation to the uplift processes of the Tibetan Plateau. The remarkable increase of aeolian dust accumulation at 3.2 Ma appears to be due to the influence of global ice volume on the East Asia monsoon. Palaeomonsoon variation during the late Tertiary as recorded in the Red Clay sequences from the Chinese Loess Plateau can be regarded as the product of a number of interacting factors, such as uplift of the Tibetan Plateau, | 孙东怀 刘东生 陈明扬 安芷生 John Shaw | 1997 | Science China Earth Sciences1997,40,4: | 27 |
| 6 | 紫色土和红壤坡面径流分离速度与水动力学参数关系研究显示文摘土壤剥蚀是土壤侵蚀、搬运和沉积过程中的一个重要子过程,对其定量研究是建立具有明确物理意义侵蚀模型的理论基础。采用放水冲刷法,在3.0m长、1.0m宽的土槽上,通过4个不同坡度(5°、10°、15°、20°)、5个不同放水流量(1.3l/min、3.0l/min、5.5l/min、6.5l/min、8.5l/min)的组合实验,对红壤和紫色土坡面径流分离速度与径流剪切力、单位水流功率、水流功率、过水断面单位能量之间的关系进行了研究。结果表明:在一定的坡度条件下,分离速度随放水流量的增大而增大,而对于相同的放水流量,分离速度呈现出先增大后减小,然后趋于稳定的趋势,且有随放水流量的增大达到峰值的时间有提前趋势。径流剪切力、单位水流功率、过水断面单位能量及水流功率四个参数与分离速度均存在着明显的线性关系,但相对而言,水流功率更能准确反应坡面分离速度的变化情况。实验条件下,红壤坡面土壤剥蚀的临界水流功率值为0.0083N/(m.s),紫色土坡面土壤剥蚀的临界水流功率值为0.062N/(m.s)。 | 丁文峰 | 2010 | 泥沙研究2010,35,6: | 25 |
| 7 | APPLICATION OF CLAYS TO REMOVAL OF RED TIDE ORGANISMS Ⅱ.COAGULATION OF DIFFERENT SPECIES OF RED TIDE ORGANISMS WITH MONTMORILLONITE AND EFFECT OF CLAY PRETREATMENT显示文摘Study on the coagulation of four species of red tide organisms(Nitzschia pungens,Skeletonema costatum,Prorocentrum minimum and Noctiluca scintillans)with montmorillonite,and the effect ofmontmorillonite pretreatment on the coagulation shows that the capability for montmorillonite to coagu-late with them is in the order:N.pungens>S.costatum>P.minimum>N.scintillans.Thecoagulation is discussed from the aspects of the structure,shape,size,movement,habit,etc.of differ-ent species and the results are explained theoretically.The experimental results also indicate that the treat-ment of montmorillonite with acid can enhance its coagulating capability.This is due to the fact that Al(OH2)6+3,exchanged from the clay lattice by hydrogen ion H+,forms hydroxy-aluminum polymers on thesurface of the montmorillonite.The hydroxy-aluminum polymers positively charge and increase the positivecharacteristic of the clay surface,and also serves as a bridge between adjacent surfaces of particles.Thesetwo functions | 俞志明 邹景忠 马锡年 | 1994 | Chinese Journal of Oceanology and Limnology1994,12,4: | 25 |
| 8 | APPLICATION OF CLAYS TO REMOVAL OF RED TIDE ORGANISMS Ⅰ.COAGULATION OF RED TIDE ORGANISMS WITH CLAYS显示文摘Coagulation of red tide organism cells with clays is discussed in theory and the effects of some fac-tors on it are studied.A quantitative model is presented which describes how the coagulation varies withpH in solution.According to the model,within the pH-range between pHzpcaand pHzpcb,VR is negativeand the coagulation is strong and strongest at pH=(pHzpca+pHzpcb)/2.It is also demonstrated that whenthe diameter of clay particles is close to that of cells,the collision probability is low,resulting in weakercoagulation.The model results have been corroborated by experiments and so are scientific and theoreticalbases for application. | 俞志明 邹景忠 马锡年 | 1994 | Chinese Journal of Oceanology and Limnology1994,12,3: | 26 |
| 9 | Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application显示文摘Erythrocytes(red blood cells, RBCs) are the most abundant circulating cells in the blood and have been widely used in drug delivery systems(DDS) because of their features of biocompatibility,biodegradability, and long circulating half-life. Accordingly, a 'camouflage' comprised of erythrocyte membranes renders nanoparticles as a platform that combines the advantages of native erythrocyte membranes with those of nanomaterials. Following injection into the blood of animal models, the coated nanoparticles imitate RBCs and interact with the surroundings to achieve long-term circulation. In this review, the biomimetic platform of erythrocyte membrane-coated nano-cores is described with regard to various aspects, with particular focus placed on the coating mechanism, preparation methods, verification methods, and the latest anti-tumor applications. Finally, further functional modifications of the erythrocyte membranes and attempts to fuse the surface properties of multiple cell membranes are discussed,providing a foundation to stimulate extensive research into multifunctional nano-biomimetic systems. | Qing Xia Yongtai Zhang Zhe Li Xuefeng Hou Nianping Feng | 2019 | Acta Pharmaceutica Sinica B2019,9,4: | 26 |
| 10 | Application of P507 and isooctanol extraction system in recovery of scandium from simulated red mud leach solution显示文摘The current recovery technique of Sc was complicated and the chemical consumption was high,This was due to the low content of Sc in resources and the difficulty of stripping.In this research,the isooctanol was added into the 2-ethylhexyl phosphonic acid mono-2-ethylhexyl ester(P507)extraction system to reduce the extraction and improve the stripping of Sc.The maximum stripping ratio of Sc from loaded organic phase by sulfuric acid can increase from 10%(without isooctanol)to 99%(with 15 vol%isooctanol).In the extraction test of the simulated red mud leaching liquor,the separation factors between Sc and Zr,Sc and Ti are 36 and 350,separately.At the same time,other metals are almost not extracted.The high selectivity and stripping of Sc suggest that the P507 with isooctanol extraction system can be applied in the practical Sc recovery process. | Chuanying Liu Li Chen Ji Chen Dan Zou Yuefeng Deng Deqian Li | 2019 | Journal of Rare Earths2019,37,9: | 22 |
| 11 | Effects of long-term green manure application on the content and structure of dissolved organic matter in red paddy soil显示文摘Dissolved organic matter(DOM) plays important roles in soil biogeochemistry activity and nutrients transportation in soils, but studies regarding the long-term effects of green manures on the content and structure of DOM in red paddy soil have not been reported yet. A long-term green manure experiment established in 1982 was utilized to test the DOM contents in different treatments, and the spectral characteristics of DOM were investigated by using ultraviolet-visible(UV-Vis) spectrometry and Fourier transform infrared(FTIR) spectrometry. The experiment included four cropping systems: ricerice-milk vetch(RRV), rice-rice-rape(RRP), rice-rice-ryegrass(RRG) and rice-rice-winter fallow(RRF), among them, milk vetch, rape, and ryegrass are popular winter green manure species in southern China. The results showed that the content of dissolved organic carbon(DOC), which is widely used to estimate the concentration of DOM, was significantly promoted after the incorporation of green manures compared with the other sampling stages. The contents of aromatic groups and the degree of humification of DOM increased in RRV and RRP, suggesting more complex compositions of the soil DOM after long-term application of milk vetch and rape. The contents of phenol, alcohol and carboxylic acid group at the mature stage of early rice were significantly higher than those at the stage of after green manures turned over, especially for the RRV treatment. The absorption ratio of FTIR indicated that winter plantation of rape increased the aromatic-C/aliphatic-C ratio, and ryegrass increased the aromatic-C/carboxyl-C ratio. In conclusion, long-term planting of milk vetch and rape as green manures increased the degree of aromaticity, humification and average molecular weight of DOM, and made the DOM more stable in red paddy soil. | GAO Song-juan GAO Ju-sheng CAO Wei-dong ZOU Chun-qin HUANG Jing BAI Jinshun DOU Fu-gen | 2018 | Journal of Integrative Agriculture2018,17,8: | 21 |
| 12 | Southeastern extension of the Red River fault zone (RRFZ) and its tectonic evolution significance in western South China Sea显示文摘Recent geophysical surveys and basin modeling suggest that the No.1 fault in the Ying- gehai basin (YGHB) is the seaward elongation of the Red River fault zone (RRFZ) in the South China Sea (SCS). The RRFZ, which separates the South China and Indochina block, extends first along the Yuedong fault, offshore of Vietnam, and then continues southward and breaks off into two branches: the Lupar fault and the Tinjia fault. The southern extension of the Lupar fault dies out beneath the NW Borneo while the Tinjia fault extends southeast and reaches the Brunei-Sabah area. According to the gravity and geomagnetic data, and the tectonic evolution of the basins, there are different evolution histories between the Wan’an basin (WAB) and the basins in the Nansha block. The Tinjia fault may be the boundary between the Balingian block and the Nansha block. Hence, the line linking the Yue- dong fault and the Tinjia fault, which both are continental margin faults and strike-slip ones in the geological evolution histories, constitute the boundary between the Indochina and Nansha block. The Lupar fault, in contrast, is an intraplate fault within the Indochina block. The results provide new hints for reconstructing the tectonic evolution history of the RRFZ and the opening of the SCS, and also a framework for hydrocarbon prospecting in the region. | LIU Baoming1,2,3, XIA Bin1, LI Xuxuan1,3, ZHANG Minqiang1,3, NIU Binhua2, ZHONG Lifeng1, JIN Qinghuan1,4 & JI Shaocheng1,5 1. Key Laboratory of Marginal Sea Geology and Resources, Chinese Academy of Sciences,Guangzhou 510640, China 2. China University of Geosciences (Beijing), Beijing 100083, China 3. Research Center of Science & Technology Department, CNOOC, Beijing 100027, China 4. Guangzhou Marine Geological Survey, Ministry of Land & Resources, Guangzhou 510075, China 5. Ecole Polytechnique Montreal, H3C3A7, Canada | 2006 | Science China Earth Sciences2006,49,8: | 20 |
| 13 | 几种主动式队列管理算法的比较研究显示文摘主动式队列管理 (ActiveQueueManagement,AQM)技术是IETF为了解决Internet拥塞控制问题而提出的一种路由器缓存管理技术 .本文对几种主要AQM算法RED、BLUE、ARED和SRED的性能在基于ns 2仿真实验的基础上进行了比较研究 .研究的性能包括队列长度、丢包概率、丢包率、连接数对吞吐量的影响及缓冲区大小对链路利用率的影响等 .仿真结果表明BLUE。 | 吴春明 姜明 朱淼良 | 2004 | 电子学报2004,32,3: | 20 |
| 14 | Red ginseng and cancer treatment显示文摘The ginseng family,including Panax ginseng(Asian ginseng),Panax quinquefolius(American ginseng),and Panax notoginseng(notoginseng),is commonly used herbal medicine.White ginseng is prepared by air-drying after harvest,while red ginseng is prepared by a steaming or heating process.The anticancer activity of red ginseng is significantly increased,due to the production of active anticancer ginsenosides during the steaming treatment,compared with that of white ginseng.Thus far,anticancer studies have been mostly focused on Asian ginseng.In this article,we review the research progress made in the anticancer activities of red Asian ginseng,red American ginseng and red notoginseng.The major anticancer mechanisms of red ginseng compounds include cell cycle arrest,induction of apoptosis/paraptosis,and inhibition of angiogenesis.The structure-function relationship analysis has revealed that the protopanaxadiol group ginsenosides have more potent effects than the protopanaxatriol group.Sugar molecules in ginsenosides inversely impact the antiproliferative potential of these compounds.In addition,ginsenoside stereoselectivity and double bond position also influence the anticancer activity.Future studies should focus on characterizing active red ginseng derivatives as potential anticancer drugs. | WANG Chong-Zhi Samantha ANDERSON DU Wei HE Tong-Chuan YUAN Chun-Su | 2016 | Chinese Journal of Natural Medicines2016,14,1: | 17 |
| 15 | Clay surface modification and its coagulation of red tide organisms显示文摘Surface modification of montmorillonite by means of Mg2+ insertion reaction has been studied and a positively charged montmorillonite has been prepared. The effects of preparation temperature and Mg2+ concentration on the positive charge property of the clay and on the clay coagulating Heterosigma akashiwo have been studied. The results showed that the modified clay enhanced the coagulation and the used amount decreased to 1/5—1/10 of the original. The removal rates of Heterosigma akashiwo were correlated positively with positive charge on the clay in accordance with theoretical model. | Zhiming Yu Xiaoxia Sun Xiuxian Song Bo Zhang | 1999 | Chinese Science Bulletin1999,44,7: | 16 |
| 16 | An 8.1Ma calcite record of Asian summer monsoon evolution on the Chinese central Loess Plateau显示文摘Carbonates in loess-red clay sequences consist mainly of calcite and dolomite. The EDTA analysis of carbonates in different size fractions and magnetic susceptibility reveal that calcite is a sensitive index of summer monsoon. The chemical analysis of carbonates and calcite from an 8.1 Ma loess-red clay sequence at Chaona on the Chinese central Loess Plateau shows that the evolution of the Asian summer monsoon experienced four stages, namely 8.1―5.5 Ma, 5.5―2.8 Ma, 2.8―1.5 Ma and 1.5―0 Ma, with increasing intensification and fluctuation, suggesting a possible combining impacts of uplift of the Tibetan Plateau and global changes on the Asian summer monsoon. | CHEN XiuLing FANG XiaoMin AN ZhiSheng HAN WenXia WANG Xin BAI Yan HONG Ye | 2007 | Science China Earth Sciences2007,50,3: | 16 |
| 17 | The Red Edge Parameters of Different Wheat Varieties Under Different Fertilization and Irrigation Treatments显示文摘The dynamics of red edge parameters at different growth stages of wheat canopy was studied.The red edge position moved to the longer wavelength from erecting stage to heading stage, and returned to the original wavelength direction from grain-filling stage to maturity stage. The leaf total nitrogen content (LTN)is positively related to red edge amplitude (d λ red) and NIR platform amplitude (d λNIRP) and the correlation coefficient improved as growth stage extended. The chlorophyll content (TChl) is negatively related to d λ red from erecting stage to the elongation stage, and positively related to d λ red from heading stage to milky maturity stage. TChl is also positively related to d λNIRP. The leaf area index (LAI) is positively related to d λ red and d λNIRP, and the correlation coefficient improved as growth stage extended. It was concluded that d λ red and d λNIRP can be used as the indicators of winter wheat growth state, and guide the fertilization and irrigation decision making. The λNIRP is suitable for derivation of LTN, the d λ red for TChl, and the d λ red or d λNIRP for LAI. | ZHAO Chun-Jiang, HUANG Wen-Jiang, WANG Ji-hua, YANG Min-hua and XUE Xu-zhang( National Engineering Center for Information Technology in Agriculture , Beijing 100089 , P. R . China) | 2002 | Agricultural Sciences in China2002,1,7: | 15 |
| 18 | APPLICATION OF CLAYS TO REMOVAL OF RED TIDE ORGANISMS Ⅲ.THE COAGULATION OF KAOLIN ON RED TIDE ORGANISMS显示文摘This article reports studies on the coagulation of kaolin(from Wuxian,Jiangsu,China)on various red tide organisms,and the observation for the first time that the coagulation of kaolin is much greaterthan that of montmorillonite so that kaolin is a more effective clay for removing red tide organisms.The authors’theoretical explanation and analysis by a mathematical-physical model prove that comparedto montmorillonite,kaolin has greater attraction for organism cells and therefore greater coagulation capabil-ity.This project’s studies on the effects of pH and acid-treatment show that the acid-treatment does not have much influence on the kaolin system;whereas the effect of pH on the kaolin system is the same asthat on the montmonrillonite system. | 俞志明 邹景忠 马锡年 | 1995 | Chinese Journal of Oceanology and Limnology1995,13,1: | 15 |
| 19 | Late Devonian red tide and mass extinction显示文摘Molecular stratigraphical, carbonate carbon isotopic, stratigraphical and paleontological data show that algal booming, eutrophication, anoxia, hypersalinity, positive δ13C excursion and biomass decreasing occurred in the offshore carbonate environments of the Frasnian-Famennian (F-F) transition, which hints that red tide might frequently take place in the F-F transition of Guangxi, South China. We suggest that the mass extinction of the reef ecosystems and the shallow-water marine organisms in the F-F transition of the lower-middle latitudes may be related to the frequent occurrence of red tide in that time. | GONG Yiming LI Baohua SI Yuanlan WU Yi | 2002 | Chinese Science Bulletin2002,47,13: | 14 |
| 20 | Paleoenvironments indicated by the fossil mammalian assemblages from red clay-loess sequence in the Chinese Loess Plateau since 8.0 Ma B.P.显示文摘Information from eleven profiles of eolian earthy red silty clay and loess of the middle of the Late Miocene to Holocene age have been studied and correlated. A complete summary profile with projected isotopic ages and fossil-bearing beds has been assembled. The profile is subdivided into 12 stratigraphic units proceeding from the lower (older) to the upper (younger) one. The character of mammalian assemblages contained in each unit was analyzed and the corresponding pa- leo-climatic environments were deduced. The environmental character of each period and the change from the middle of the Late Miocene at about 8.0 Ma B.P. up to the Holocene progressed from the hot semiarid and semi-moist, warmer-moist, warm-moister of the Late Miocene. To slightly less warm moist, cool-dry, slight-warmer-moister of the Pliocene; later the cool to cold dry periods alternated frequently with the mild semiarid and semi-moist periods of the Quaternary. Vegetation progressed from the grasslands with sparse woods, wooded shrub-grasslands and subtropical forest-grasslands of the Late Miocene age to sparse grasslands and dry grasslands of the Pliocene; and to sparse grasslands, dry grasslands and tundras of the Quaternary. The climate changes in the Neogene were of low-amplitute in a generally warm-humid background. Those of the Quaternary were of higher am- plitude with a longer phase. Cool or cold dry and slightly warm semiarid and semi-moist climates al- ternated on a generally cool-dry background. The tendency since the start of the Quaternary was the change to more northern and western shift in the Loess Plateau, with progressively cooler and dryer conditions. The dramatic uplift of the Qinghai-Xizang (Tibet) Plateau and the forming and expansion of the Arctic ice sheet might be the main reasons of the more pronounced changes in the Quaternary. | XUE Xiangxu1,2, ZHANG Yunxiang1,2 & YUE Leping1,2 1. State Key Laboratory of Continent Dynamics (Northwest University), Institute of Cenozoic Geology and Environment, De- partment of Geology, Northwest University, Xi’an 710069, China 2. Institute of Earth Environment, State Key Laboratory of Loess and Quaternary Geology, Chinese Academy of Sciences, Xi’an 710075, China | 2006 | Science China Earth Sciences2006,49,5: | 13 |