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| 1 | 中亚-蒙古造山带东段的锡林郭勒杂岩:早华力西期造山作用的产物而非古老陆块?——锆石SHRIMP U-Pb年代学证据显示文摘锡林郭勒杂岩是华北板块北缘古生代褶皱带内出露面积最大的变质岩系,以前多被当着前寒武纪的古老地块。本文通过对该杂岩中副片麻岩和正片麻岩的锆石SHRIMP U-Pb年代学研究发现,副片麻岩中的锆石多为岩浆锆石,其^(206)Pb/^(238)U加权平均年龄为406±7Ma,指示它们的原岩主要是由近同期(略早些)的岩浆岩风化后就近沉积的产物,该年龄应代表源区(岛弧型?)花岗岩的形成时间,同时也是副片麻岩原岩沉积的下限年龄。正片麻岩中岩浆锆石的^(206)Pb/^(238)U加权平均年龄为382±2Ma,代表花岗片麻岩原岩的侵位年龄。岩石中锆石的变质增生边的形成年龄为337±6Ma,代表锡林郭勒杂岩发生变质和变形的时间,该变质事件可能与贺根山缝合带内所发生的一次主要的碰撞造山作用有关。这些年龄资料充分说明,锡林郭勒杂岩并非古老地块,而是华力西早期岩浆作用、沉积作用和变质作用事件的产物.整个事件是在较短的时间范围内(~70Ma)完成的,推测该杂岩发育在碰撞造山带的弧前环境。中亚-蒙古造山带东南部(内蒙古的中、东部)碰撞前的构造格局可能不是典型的多岛洋体制,由于缺少古老的陆块,造山过程更多的表现为大洋的大陆化过程,即洋内俯冲形成岛弧,岛弧在被动大陆边缘拼贴聚合转化为新的大陆。 | 薛怀民 郭利军 侯增谦 周喜文 童英 潘晓菲 | 2009 | 岩石学报2009，25，8： | 63 |
| 2 | 在心血管的疾病的先进 glycation 结束产品的角色显示文摘 Advanced glycation end products(AGEs) are produced through the non enzymatic glycation and oxidation of proteins,lipids and nucleic acids.Enhanced formation of AGEs occurs particularly in conditions associated with hyperglycaemia such as diabetes mellitus(DM).AGEs are believed to have a key role in the development and progression of cardiovascular disease in patients with DM through the modif ication of the structure,function and mechanical properties of tissues through crosslinking intracellular as well as extracellular matrix proteins and through modulating cellular processes through binding to cell surface receptors [receptor for AGEs(RAGE)].A number of studies have shown a correlation between serum AGE levels and the development and severity of heart failure(HF).Moreover,some studies have suggested that therapies targeted against AGEs may have therapeutic potential in patients with HF.The purpose of this review is to discuss the role of AGEs in cardiovascular disease and in particular in heart failure,focussing on both cellular mechanisms of action as well as highlighting how targeting AGEs may represent a novel therapeutic strategy in the treatment of HF. | Zeinab Hegab Stephen Gibbons Ludwig Neyses Mamas A Mamas | 2012 | World Journal of Cardiology2012，4，4： | 58 |
| 3 | Nature brings new avenues to the therapy of central nervous system diseases——an overview of possible treatments derived from natural products显示文摘Natural products(NPs), including traditional Chinese medicine(TCM), have been long and widely used in the prevention and treatment of central nervous system(CNS) diseases by virtue of their abundant sources, diverse structures, and novel activities.In this review article, we intend to summarize and discuss the situation or status of the clinical employments or trials of the NPs and their derivatives with CNS activities. NPs that have been extensively studied in preclinical research in recent years are also included. The compounds presented in this review are classified according to their indications and followed by details such as natural sources, possible biological mechanisms, and development status, while a considerable proportion of them are found in TCM. In addition, some drug combinations with synergistic effects are also mentioned. According to their impressive therapeutic effects and novel chemical structures, NPs are not only effective therapeutic remedies in clinic, but also lead compounds for structural modification, which indicate that nature brings new avenues to the therapy of CNS diseases. | Junchi Zhang Yang He Xiangrui Jiang Hualiang Jiang Jingshan Shen | 2019 | Science China(Life Sciences)2019，62，10： | 30 |
| 4 | Update on type 2 diabetes-related osteoporosis显示文摘It was previously understood that body weight gain and obesity observed in type 2 diabetes mellitus(T2DM) could be beneficial since body weight increase elevated bone mineral density and thus helped maintain the skeletal framework.However,a number of recent findings in humans and rodents have revealed that T2 DM is not only associated with trabecular defects but also increases cortical porosity,and compromised bone cell function and bone mechanical properties.Hyperglycemia and insulin resistance in T2 DM may further induce osteoblast apoptosis and uncoupling bone turnover.Prolonged accumulation of advanced glycation end products and diminished activity of lysyl oxidase,an essential enzyme for collagen cross-link,can lead to structural abnormalities of bone collagen fibrils,brittle matrix,and fragility fractures.Our studies in T2 DM rats showed that dyslipidemia,which often occurs in T2 DM,could obscure the T2DM-associated changes in bone microstructure and osteopenia.Longitudinal bone growth regulated by the growth plate chondrocytes is also impaired by T2 DM since differentiation of growth plate chondrocytes is arrested and retained in the resting state while only a small number of cells undergo hypertrophic differentiation.Such a delayed chondrocyte differentiation may have also resulted from premature apoptosis of the growth plate chondrocytes.Nevertheless,the underlying cellular and molecular mechanisms of insulin resistance in osteoblasts,osteoclasts,osteocytes,and growth plate chondrocytes remain to be investigated. | Kannikar Wongdee Narattaphol Charoenphandhu | 2015 | World Journal of Diabetes2015，6，5： | 26 |
| 5 | Management of diabolical diabetes mellitus and periodontitis nexus: Are we doing enough?显示文摘Periodontitis is the commonest oral disease affecting population worldwide.This disease is notorious for the devastation of tooth supporting structures,ensuing in the loss of dentition.The etiology for this disease is bacterial biofilm,which accumulates on the teeth as dental plaque.In addition to the biofilm microorganisms,other factors such as environmental,systemic and genetic are also responsible in progression of periodontitis.Diabetes mellitus(DM) is metabolic disorder which has an impact on the global health.DM plays a crucial role in the pathogenesis of periodontitis.Periodontitis is declared as the 'sixth' major complication of DM.Evidence based literature has depicted an enhanced incidence and severity of periodontitis in subjects with DM.A 'two way' relationship has been purported between periodontitis and DM.Mutual management of both conditions is necessary.Periodontal therapy(PT) may assist to diminish the progression of DM and improve glycemic control.Various advanced technological facilities may be utilized for the purpose of patient education and disease management.The present paper clarifies the etio-pathogenesis of periodontitis,establishing it as a complication of DM and elaborating the various mechanisms involved in the pathogenesis.The role of PT in amelioration of DM and application of digital communication will be discussed.Overall,it is judicious to create an increased patient cognizance of the periodontitis-DM relationship.Conjunctive efforts must be undertaken by the medical and oral health care professionals for the management of periodontitis affected DM patients. | Abhijit N Gurav | 2016 | World Journal of Diabetes2016，7，4： | 22 |
| 6 | Fish sauce and gastric cancer:an ecological study in Fujian Province,China显示文摘AIM To explore the relationship betweenconsumption of fish sauce and the risk of gastriccancer in Fujian Province.METHODS An ecological study was carriedout.A total of 11000 subjects from 55 townshipswere randomly selected from 10 counties withinFujian Province.All subjects were localresidents who had been living in Fujian Provincefor more than 20 years,within the age group of45-74 years.Trained interviewers conductedface-to-face interviews with a standardizedquestionnaire,which covered the frequency andamount of food intake,dietary habit,tobaccoand alcohol consumption and history of chronicgastric diseases.Univariate and multivariateanalyses were performed using Epi-info and SASstatistical packages,respectively.RESULTS A significant correlation betweenmonthly consumption of fish sauce and mortalityof gastric cancer was found.Pearson’scoefficient of correlation was statisticallysignificant with r=0.7356 for males,r=0.5246for females(P<0.01).In the multivariateanalysis,consumption of fish sauce still showedan association with the risk of gastric cancer.No significant positive correlation betweenesophagus cancer,liver cancer,colon cancerand consumption of fish sauce were observed.CONCLUSION Long-term intake of fish saucemay be related to high mortality of gastriccancer.Consumption of fish sauce might be oneof important and unique etiologic factors ofgastric cancer in Fujian Province.Furtherstudies are needed to confirm this ecologicalstudy. | Lin Cai Shun Zhang Yu Wei Min Ye Ying Nan Yi | 2000 | World Journal of Gastroenterology2000，6，5： | 18 |
| 7 | Puerarin enhances superoxide dismutase activity and inhibits RAGE and VEGF expression in retinas of STZ-induced early diabetic rats显示文摘Objective:To investigate the effects of puerarin on the activity of superoxide dismutase(SOD), and expressions of advanced glycation end-product(AGE) receptor(RAGE) and vascular endothelial growth factor(VEGF) in retinas of streptozotocin(STZ)-induced early diabetic rats. Methods:Diabetic rat models were established by inducing diabetes via intra-peritoneal injection of STZ.Rats were randomly divided into normal(control),diabetic(DM),and DM+ puerarin groups.After intra-gastric administration of puerarin(500 mg/kg/day for 4 weeks),levels of SOD and malondialdehyde(MDA) were determined in serum and retina.mRNA and protein expression levels of RAGE and VEGF in retinas were determined by real-lime polymerase chain reaction(RT-PCR)(mRNA) and Western blot analysis(protein levels).Results:There was significantly lower SOD activity and significantly higher MDA in serum and retinas of the DM group compared with the two other groups(P<0.05).After treatment with puerarin,SOD activity increased and MDA content decreased in this group(P<0.05).mRNA and protein expression levels of RACE and VECF in the DM group were significantly higher than those of the other groups (P<0.05),and decreased after puerarin treatment(P<0.05).Conclusions:Puerarin is able to enhance SOD activity,and inhibit RAGE and VEGF expressions in retinas of STZ-induced early diabetic ruts. | Fang Chen Hong-Quan Zhang Jun Zhu Kai-Yang Liu Hong Cheng Guo-Li Li Shan Xu Wei-Hong Lv Zheng-Gao Xie | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，11： | 16 |
| 8 | Clinical Utility of the Ratio Between Circulating Fibrinogen and Fibrin (ogen) Degradation Products for Evaluating Coronary Artery Disease in Type 2 Diabetic Patients显示文摘Background: We investigated whether and to what extent the ratio between circulating fibrinogen (Fg) and its degradation products (FDP) reflects the severity of coronary artery disease (CAD) in type 2 diabetic patients. Methods: Plasma levels of Fg and FDP were determined, and Fg/FDP ratio was calculated in 344 consecutive patients with type 2 diabetes and chest pain on exertion undergoing coronary angiography. The severity of CAD was evaluated by the number of significant CAD (〉50% luminal diameter narrowing) and Gensini score. Results: Plasma Fg was higher, but Fg/FDP ratio was lower in patients with significant CAD (n = 255) compared with those without (n = 89), due to a disproportionate increase in FDP. Fg and FDP correlated positively, while Fg/FDP ratio negatively, with the number of diseased coronary arteries and the tertile of Gensini score (all P values for trend 〈 0.01). After adjusting for age, sex, risk factors for CAD, lipid profiles, glycosylated hemoglobin A1 c, creatinine, leukocyte count, and high-sensitivity C-reactive protein, Fg/FDP ratio remained an independent determinant for multivessel coronary disease (MVD) (odds ratio [OR], 0.869; 95% confidence interval [C/], 0.788~).958, P = 0.005) and high tertile of Gensini score (OR, 0.797, 95% CI, 0.682-0.930, P = 0.004). The area under the curve of Fg/FDP ratio was larger than that of Fg for predicting the presence of MVD (0.647 vs. 0.563, P = 0.048) and Gensini score 〉 30 (0.656 vs. 0.538, P = 0.026). Conclusions: Elevated plasma Fg and FDP level and reduced Fg/FDP ratio are associated with presence of CAD, and Fg/FDP ratio is superior to Fg in reflecting severe coronary atherosclerosis for patients with type 2 diabetes. | Wei-Xin Xiong Ying Shen Dao-Peng Dai Lin Lu Qi Zhang Rui-Yan Zhang Wei-Feng Shen Rong Tao | 2015 | Chinese Medical Journal2015，，6： | 16 |
| 9 | Exploring alternative treatments for Helicobacter pylori infection显示文摘Helicobacter pylori(H. pylori) is a successful pathogen that can persist in the stomach of an infected person for their entire life. It provokes chronic gastric inflammation that leads to the development of serious gastric diseases such as peptic ulcers, gastric cancer and Mucosa associated lymphoid tissue lymphoma. It is known that these ailments can be avoided if the infection by the bacteria can be prevented or eradicated. Currently, numerous antibiotic-based therapies are available. However, these therapies have several inherent problems, including the appearance of resistance to the antibiotics used and associated adverse effects, the risk of re-infection and the high cost of antibiotic therapy. The delay in developing a vaccine to prevent or eradicate the infection has furthered research into new therapeutic approaches. This review summarises the most relevant recent studies on vaccine development and new treatments using natural resources such as plants, probiotics and nutraceuticals. In addition, novel alternatives based on microorganisms, peptides, polysaccharides, and intragastric violet light irradiation are presented. Alternative therapies have not been effective in eradicating the bacteria but have been shown to maintain low bacterial levels. Nevertheless, some of them are useful in preventing the adverse effects of antibiotics, modulating the immune response, gastroprotection, and the general promotion of health. Therefore, those agents can be used as adjuvants of allopathic anti-H. pylori eradication therapy. | Guadalupe Ayala Wendy Itzel Escobedo-Hinojosa Carlos Felipe de la Cruz-Herrera Irma Romero | 2014 | World Journal of Gastroenterology2014，20，6： | 16 |
| 10 | Advanced oxidation protein products decrease expression of nephrin and podocin in podocytes via ROS-dependent activation of p38 MAPK显示文摘Accumulation of plasma advanced oxidation protein products(AOPPs) promotes progression of proteinuria and glomerulo-sclerosis.To investigate the molecular basis of AOPPs-induced proteinuria,normal Sprague-Dawley rats were treated with AOPPs-modified rat serum albumin.The expression of glomerular podocyte slit diaphragm(PSD)-associated proteins,nephrin and podocin,was significantly decreased coincident with the onset of albuminuria in rats treated with AOPPs.Chronic inhibi-tion of NADPH oxidase by apocynin prevented down-regulation of nephrin and podocin and decreased albuminuria in AOPPs-challenged rats.This suggested that accumulation of AOPPs promotes proteinuria,possibly via down-regulating the expression of PSD-associated proteins. | YANG Li,LIANG Min,ZHOU QiuGen,XIE Di,LOU AiJu,ZHANG Xun & HOU FanFan Key Laboratory for Organ Failure Research,Division of Nephrology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China. | 2010 | Science China(Life Sciences)2010，53，1： | 14 |
| 11 | Quality of healing of gastric ulcers: Natural products beyond acid suppression显示文摘Gastric ulcer is a chronic disease featured with unexpected complications, including bleeding, stenosis and perforation, as well as a high incidence of recurrence. Clinical treatments for gastric ulcer have allowed the rapid development of potent anti-ulcer drugs during the last several decades. Gastric ulcer healing is successful with conventional treatments including H2-receptor antagonists, and proton pump inhibitors(PPIs) have been essential for ulcer healing and prevention of complications. Additionally, Helicobacter pylori eradication therapy is effective in reducing ulcer recurrence and leads to physiological changes in the gastric mucosa which affect the ulcer healing process. However, in spite of these advancements, some patients have suf-fered from recurrence or intractability in spite of continuous anti-ulcer therapy. A new concept of the quality of ulcer healing(QOUH) was initiated that considers the reconstruction of the mucosal structure and its function for preventing ulcer recurrence. Although several gastroprotection provided these achievements of the QOUH, which PPI or other acid suppressants did not accomplish, we found that gastroprotection that originated from natural products, such as a newer formulation from either Artemisia or S-allyl cysteine from garlic, were very effective in the QOUH, as well as improving clinical symptoms with fewer side effects. In this review, we will introduce the importance of the QOUH in ulcer healing and the achievements from natural products. | Napapan Kangwan Jong-Min Park Eun-Hee Kim Ki Baik Hahm | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，1： | 14 |
| 12 | Review on Volatile Flavor Components of Roasted Oilseeds and Their Products显示文摘Volatile flavor components in foods are the key quality parameters. The researchers conducted in-depth research on sesame oil, peanut oil, rapeseed oil, sunflower oil, sesame paste and peanut butter, etc. However, there is no comprehensive summary about the flavor of roasted oilseeds and their products. The occurrence and the formation mechanisms of the main volatile flavor substances,and the impacts of processing factors are discussed in this review, which may provide references for further research on volatile flavor compounds, identification and evaluation of specific products and development of new products. | LI Cuicui HOU Lixia | 2018 | Grain & Oil Science and Technology2018，1，4： | 12 |
| 13 | RESEARCH ON THE WATER-RESISTANCE OF MAGNESIUM OXYCHLORIDE CEMENT——I:THE STABILITY OF THE REACTION PRODUCTS OF MAGNESIUM OXYCHLORIDE CEMENT IN WATER显示文摘In this paper.the change of the crystalline phasesin hardened magnesium oxychloride cement(MOC)paste inwater was analyzed by XRD.It was developed that the reactionproducts 5 phase or 3 phase of MOC are instable in water andcan be changed into Mg(OH)2 by the action of water,whichcauses the content of 5 phase or 3 phase to be less and less,thecontent of Mg(OH)2 to be more and more and the strength to bethe lower the lower,after hardended MOC paste was immersedin water.The change of 5 phase and 3 phase into Mg(OH)2 isnot a dissolve process,but a hydrolysis process.The hydrolysisproducts of 5 phase and 3 phase are Mg(OH)2 precipitationand soluble Cl-,Mg+ ions and H2O.The hydrolysis is sponta-neous thermodlynamically and its chemical kinatic equation is C=Coe-kt Thus,it is suggested that only by enhancing the stabilityof 5 phase or 3 phase in water and preventing 5 phase or 3phase from the hydrolyzing can the water resistance of MOC beimproved well. | 张传镁 邓德华 | 1994 | Journal of Wuhan University of Technology(Materials Science)1994，9，3： | 9 |
| 14 | 一株产紫杉醇的曼地亚红豆杉内生真菌的分离及鉴定(摘要)(英文)显示文摘[目的]分离并鉴定1株产紫杉醇的曼地亚红豆杉内的内生真菌。[方法]从曼地亚红豆杉树皮内表皮中分离得到32株内生真菌,并通过高效液相色谱法检测其发酵产物。[结果]筛选获得1株可以产紫杉醇的内生真菌M57,其紫杉醇产量为45~50μg/L,并通过对M57菌落的形态学观察以及18S rDNA序列分析初步将其鉴定为根霉属(Rhizopus)真菌。[结论]该菌株的发现为微生物发酵法生产紫杉醇提供了具有潜在应用价值新的菌种。 | 李佟清 张志建 张鹏 王春兰 刘博 刘婷婷 付春华 余龙江 | 2010 | Agricultural Science & Technology2010，11，5： | 8 |
| 15 | Degradation mechanisms of oxytetracycline in the environment显示文摘Over the past few decades,the usage of oxytetracycline(OTC),a kind of antibiotic,has increased with the development of aquaculture and livestock breeding.However,about 30–90%of the applied antibiotics are excreted as the parent compounds into the environment,especially with the application of animal manure to agricultural fields.This large influx of antibiotics may lead to the destruction of the natural microbial ecological community and pose great threats to human beings through the food chain.Therefore,the fate and toxicity of OTC in the environment are issues of great concern.Degradation of OTC,including the non-biodegradation and biodegradation,and the biological toxicity of its degradation products or metabolites,are reviewed in this paper.The non-biodegradation pathways include hydroxylation,quinonization,demethylation,decarbonylation,dehydration and secondary alcohol oxidation.Light(particularly UV light),pH and oxidizing substances play important roles in non-biodegradation.Biodegradation products include 4-epi-OTC(EOTC),2-acetyl-2-decarboxy-amido-OTC(ADOTC),α-apo-OTC andβ-apo-OTC.EOTC is an epimer and identied except for the configuration of the C4 dimethylamino group of OTC.Temperature and pH are the main factors affecting biodegradation pathways of OTC.In addition,this review discusses concerns over the biological toxicity of OTC degradation products. | LI Zhao-jun QI Wei-ning FENG Yao LIU Yuan-wang Ebrahim Shehata LONG Jian | 2019 | Journal of Integrative Agriculture2019，18，9： | 8 |
| 16 | Application of Rare Earth Phosphate Fertilizer in Western Area of China显示文摘Rare earth phosphate fertilizer (REPF) as base fertilizer (750 kg per hm2) was applied in the western area of China during the 'Tenth Five-Year Plan', and the results show as follows: compared with calcium superphosphate (CK), REPF increases crops yields for maize by 17.0%, for rice by 10.5%, for wheat by 24.2%, for potato by 18.5%, for cabbage by 16.3%, for Chinese cabbage by 16.4%, for beet by 6.5%; decreases the diseased plant rate for common smut of maize by 1.0%, for maize stalk rot by 1.2%, for wheat take-all disease by 7.8%, for wheat root rot by 3.2%, for potato blackleg disease by 1.4%, for potato late blight by 6.6%; increases the sugar content of beet by 0.9°S. | 刘向生 王甲辰 杨军 樊玉斌 伍艳平 张赫 | 2006 | Journal of Rare Earths2006，24，z2： | 8 |
| 17 | Empirical Research on Influencing Factors of Trade Competitiveness of China's Agricultural Products显示文摘Based on the analysis of the indices of RCA and TSC of agricultural products in China,according to China Statistical Yearbook,China Rural Statistical Yearbook and data from database of The Food and Agriculture Organization of the United Nations from 1996 to 2009,We select direct influencing factors and indirect influencing factors as reference as series of numbers,regard indices of RCA and TSC as index series of numbers of evaluation,and use grey correlation analysis method to conduct analysis and evaluation on influencing factors of trade competitiveness of China's agricultural products.The results show that due to different index calculation methods,the sequencing results of all factors are not wholly the same.But on the whole,in terms of transformation from cost advantage and price advantage into competition advantage,the ability of direct factors is strong,impacting significantly trade competitiveness of China's agricultural products,while the influencing effect of indirect factors is relatively weak.On the basis of this,we put forward the suggestions in order to improve trade competitiveness of China's agricultural products as follows:firstly,we should strengthen and perfect agricultural agriculture-support policy;secondly,we should promote foreign merchants’ direct investment level in agriculture;thirdly,we should deepen the processing ability of agricultural products and promote quality of agricultural products;fourthly,we should create good trade environment. | MIAO Qiang1,LIU Yong-sheng1,WANG Xiao-yuan2 1.Department of Economics and Management,Tianjin Agricultural University,Tianjin 300384,China 2.The School of Economics,Nankai University,Tianjin 300071,China | 2011 | Asian Agricultural Research2011，3，4： | 7 |
| 18 | Glycated hemoglobin and its spinoffs: Cardiovascular disease markers or risk factors?显示文摘Atherosclerosis is a major complication of diabetes, increasing the risk of cardiovascular related morbidities and mortalities. The hallmark of diabetes is hyperglycemia which duration is best predicted by elevated glycated haemoglobin A1C(Hb A1C) levels. Diabetic complications are usually attributed to oxidative stress associated with glycation of major structural and functional proteins. This non-enzymatic glycation of long lived proteins such as collagen, albumin, fibrinogen, liver enzymes and globulins result in the formation of early and advanced glycation end products(AGEs) associated with the production of myriads of free radicles and oxidants that have detrimental effects leading to diabetic complications. AGEs have been extensively discussed in the literature as etiological factors in the advancement of atherogenic events. Mechanisms described include the effects of glycation on protein structure and function that lead to defective receptor binding, impairment of immune system and enzyme function and alteration of basement membrane structural integrity. Hemoglobin(Hb) is a major circulating protein susceptible to glycation. Glycated Hb, namely Hb A1 C is used as a useful tool in the diagnosis of diabetes progression. Many studies have shown strong positive associations between elevated Hb A1 C levels and existing cardiovascular disease and major risk factors. Also, several studies presented Hb A1 C as an independent predictor of cardiovascular risk. In spite of extensive reports on positive associations, limited evidence is available considering the role of glycated Hb in the etiology of atherosclerosis. This editorial highlights potential mechanisms by which glycated hemoglobin may contribute, as a causative factor, to the progression of atherosclerosis in diabetics. | Jumana Saleh | 2015 | World Journal of Cardiology2015，7，8： | 7 |
| 19 | 山东省蔬菜产地灌溉水重金属环境质量分析与评价(摘要)(英文)显示文摘[目的]评价山东省蔬菜基地灌溉水重金属环境质量。[方法]对山东省主要蔬菜产地的灌溉水进行了重金属Hg、Cd、As、六价Cr、Pb、Cu和Zn含量的抽样调查分析,并采用单项质量指数与综合质量指数相结合的方法对重金属的环境质量状况进行了评价。[结果]寿光、莱阳、金乡和章丘4个蔬菜产地灌溉水中各重金属的平均含量均远低于《食用农产品产地环境质量评价标准》(HJ332-2006)规定的限值,未发现重金属含量超标现象;4地灌溉水重金属的单项质量指数均小于0.5,综合质量指数分别为0.3178、0.3204、0.2326和0.2607,灌溉水环境质量均为1级。[结论]4个蔬菜产地的灌溉水环境质量属于清洁水平,适宜作为无公害蔬菜的灌溉用水。 | 刘苹 魏建林 于淑芳 杨力 Jian-lin Shu-fang | 2010 | Agricultural Science & Technology2010，11，5： | 7 |
| 20 | Fatty liver diseases, mechanisms, and potential therapeutic plant medicines显示文摘The liver is an important metabolic organ and controls lipid, glucose and energy metabolism. Dysruption of hepatic lipid metabolism is often associated with fatty liver diseases, including nonalcoholic fatty liver disease(NAFLD), alcoholic fatty liver diseases(AFLD) and hyperlipidemia. Recent studies have uncovered the contribution of hormones, transcription factors, and inflammatory cytokines to the pathogenesis of dyslipidemia and fatty liver diseases. Moreover, a significant amount of effort has been put to examine the mechanisms underlying the potential therapeutic effects of many natural plant products on fatty liver diseases and metabolic diseases. We review the current understanding of insulin, thyroid hormone and inflammatory cytokines in regulating hepatic lipid metabolism, focusing on several essential transcription regulators, such as Sirtuins(SIRTs), Forkhead box O(FoxO), Sterol-regulatory element-binding proteins(SREBPs). We also discuss a few representative natural products with promising thereapeutic effects on fatty liver disease and dyslipidemia. | ZHU Jia-Zhen YI Hong-Wei HUANG Wei PANG Tao ZHOU Hui-Ping WU Xu-Dong | 2020 | Chinese Journal of Natural Medicines2020，18，3： | 7 |
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