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Effects of glycyrrhetinic acid on collagen metabolism of hepatic stellate cells at different stages of liver fibrosis in rats

查看全文 作  者:Ji Yao Wang;Qi Sheng Zhang;Ji Sheng Guo;Mei Yu Hu Department of Gastroenterology, Zhongshan Hospital, Medical Center, Fu Dan University Shanghai Medical University), Shanghai 200032, China 高影响力作者 出  处:《World Journal of Gastroenterology》索引2001年第7卷第1期,共5页高影响力期刊 基  金:Project supported by the National Natural Science Foundation of China, No. 39500138 摘  要:INTRODUCTIONLiver fibrosis is a dynamic course leading tocirrhosis from a various chronic liver diseases. Thepathological basis of fibrosis is the disturbance ofproduction and degradation of the extracellularmatrix (ECM), which causes accumulation of ECMin the liver[1,2]. 关 键 词:liver CIRRHOSIS glycyrrhetinic acid PROCOLLAGEN CLOSTRIDIUM histolyticum COLLAGENASE EXTRACELLULAR matrix gene expression IMMUNOHISTOCHEMISTRY
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