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Summary of the Detection Kits for SARS-CoV-2 Approved by the National Medical Products Administration of China and Their Application for Diagnosis of COVID-19

查看全文 作  者:Ruhan [1]A;Huijuan [1]Wang;Wenling [1]Wang;Wenjie [1]Tan 高影响力作者 机构地区:[1]NHC Key Laboratory of Biosafety,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China高影响力机构 出  处:《Virologica Sinica》索引2020年第35卷第6期,共14页高影响力期刊 基  金:supported by the National Key Program for Infectious Disease of China(2018ZX10101002);the National Key Research and Development Program of China(2016YFD0500301,2020YFC0840900)。 摘  要:The on-going global pandemic of coronavirus disease 2019(COVID-19)caused by a novel coronavirus called severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has been underway for about 11 months.Through November 20,2020,51 detection kits for SARS-CoV-2 nucleic acids(24 kits),antibodies(25 kits),or antigens(2 kits)have been approved by the National Medical Products Administration of China(NMPA).Convenient and reliable SARS-CoV-2 detection assays are urgently needed worldwide for strategic control of the pandemic.In this review,the detection kits approved in China are summarised and the three types of tests,namely nucleic acid,serological and antigen detection,which are available for the detection of COVID-19 are discussed in detail.The development of novel detection kits will lay the foundation for the control and prevention of the COVID-19 pandemic globally. 关 键 词:Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) Detection kits Real-time RT-PCR Lateral flow immunoassay(LFIA) Chemiluminescence immunoassay(CLIA)
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