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Electrospun Nanofibrous Materials for Wound Healing

查看全文 作  者:Yuping [1]Dong;Yuqi [2]Zheng;Keyan [1]Zhang;Yueming [1]Yao;Lihuan [1]Wang;Xiaoran [3]Li;Jianyong [3]Yu;Bin [1,3]Ding 高影响力作者 机构地区:[1]State Key Laboratory for Modification of Chemical Fibers and Polymer Materials,College of Textiles,Donghua University,Shanghai 201620,China;[2]College of Materials Science and Engineering,Donghua University,Shanghai 201620,China;[3]Innovation Center for Textile Science and Technology,Donghua University,Shanghai 200051,China高影响力机构 出  处:《Advanced Fiber Materials》索引2020年第2卷第4期,共16页高影响力期刊 基  金:This work was supported by the National Natural Science Foundation of China(81771338);Natural Science Foundation of Shanghai(19ZR1470500);the Science and Technology Commission of Shanghai Municipality(18511109500);the Fundamental Research Funds for the Central Universities(223201900081). 摘  要:Wound dressing materials which are capable of meeting the demands of accelerating wound closure and promoting wound healing process have being highly desired.Electrospun nanofibrous materials show great application potentials for wound healing owing to relatively large surface area,better mimicry of native extracellular matrix,adjustable waterproofness and breathability,and programmable drug delivery process.In this review article,we begin with a discussion of wound healing process and current commercial wound dressing materials.Then,we emphasize on electrospun nanofibrous materials for wound dressing,covering the efforts for controlling fiber alignment and morphology,constructing 3D scaffolds,developing waterproof-breathable membrane,governing drug delivery performance,and regulating stem cell behavior.Finally,we finish with challenges and future prospects of electrospun nanofibrous materials for wound dressings. 关 键 词:ELECTROSPUN Wound dressings Waterproofness Breathability Drug delivery Stem cell therapy
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