|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Electrospun Nanofibrous Materials for Wound Healing显示文摘Wound dressing materials which are capable of meeting the demands of accelerating wound closure and promoting wound healing process have being highly desired.Electrospun nanofibrous materials show great application potentials for wound healing owing to relatively large surface area,better mimicry of native extracellular matrix,adjustable waterproofness and breathability,and programmable drug delivery process.In this review article,we begin with a discussion of wound healing process and current commercial wound dressing materials.Then,we emphasize on electrospun nanofibrous materials for wound dressing,covering the efforts for controlling fiber alignment and morphology,constructing 3D scaffolds,developing waterproof-breathable membrane,governing drug delivery performance,and regulating stem cell behavior.Finally,we finish with challenges and future prospects of electrospun nanofibrous materials for wound dressings. | Yuping Dong Yuqi Zheng Keyan Zhang Yueming Yao Lihuan Wang Xiaoran Li Jianyong Yu Bin Ding | 2020 | Advanced Fiber Materials2020，2，4： | 10 |
| 2 | CONTROL OF DIMENSIONAL STABILITY AND DEGRADATION RATE IN ELECTROSPUN COMPOSITE SCAFFOLDS COMPOSED OF POLY(D,L-LACTIDE-co-GLYCOLIDE) AND POLY(ε-CAPROLACTONE)显示文摘The purpose of this study is to investigate the effect of composition poly(D,L-lactide-co-glycolide)/poly(ε- caprolactone)(PLGA/PCL)blending on the morphology,shrinkage and degradation behaviors of the electrospun fibers. With the increase of PLGA content in the composite fibers,the average diameter of the electrospun fibers increased from 1.35μm to 1.95μm.The serious shrinking of the electrospun PLGA meshes could be circumvented by adding 20% PCL in the fibers,resulting from the semi-crystalline nature ... | Yi-jie Liu Hong-liang Jiang~(**) Yan Li Kang-jie Zhu Department of Polymer Science and Engineering,Zhejiang University,Hangzhou 310027,China | 2008 | Chinese Journal of Polymer Science2008，26，1： | 3 |
| 3 | PLLA-PCys co-electrospun fibers for capture and elution of glutathione S-transferase显示文摘The copolymer poly(L-lactic acid)-b-poly(L-cysteine) (PLA-b-PCys) was co-electrospun with PLGA into ultrafine fibers. The reduced glutathione (GSH) was conjugated to the fiber surfaces via disulfide bonds. The glutathione S-transferase (GST) was captured onto the GSH fibers via specific substrate-enzyme interaction between the bound GSH and GST. The captured GST was eluted with free GSH aqueous solution and lyophilized to get pure GST powders. The results show that the GSH moieties on the fiber surface retain the bioactivity of the free GSH and thus they can bind specifically with GST and the GST in solution is captured onto the fiber surface. In addition, the bound GSH is not as active as free GSH so that the captured GST can be eluted off from the fiber by free GSH aqueous solution. Based on this principle, GST itself or its fused proteins can be separated and purified very easily. The preliminary purification efficiency is 6.5 mg·(gPCys)-1. Further improvements are undertaken. | LU TianCheng SUN Jing DONG XiaoQing CHEN XueSi WANG Yu JING XiaBin | 2009 | Science China Chemistry2009，52，12： | 3 |
| 4 | Surface structure change properties:Auto-soft bionic fibrous membrane in reducing postoperative adhesion显示文摘Peritoneal adhesion is the most common adverse effect following abdominal surgery or inflammation.The occurrence in clinical trials has been successfully reduced using barriers.However,the shortcomings of frequently used adhesion barriers,such as rapid degradation rate of gel barrier and inadequate operation ability of solid barrier,cannot be ignored.In this study,a fibrous membrane with an ECM-like structure was prepared.The adhesion properties were reduced significantly by changing the surface structure.The fibrous membrane caused less inflammatory response and much less peripheral adhesion and intestinal obstruction compared to the casting film and the commercial film with smooth surface,though with the same components.Because of the auto-soft bionic structure and similarity in the mechanical modulus of the tissues,the fibrous membrane was more flexible when it adhered to the tissues,showed excellent effectiveness and biocompatibility.In addition to the rat and miniature pig models,a randomized,placebo-controlled,and multicenter clinical pilot study with 150 patients confirmed that because of its flexibility,biodegradability,and similarity to mechanical modulus and structure with tissues involved,the fibrous membrane served as a favorable implant for preventing post-operation adhesion. | Shanshan Xu Chenhong Wang Ruoqing Mao Xiaoyu Liang Heran Wang Zhenyu Lin Jiangxue Li Shilin Li Jipeng Jiang Tongshuo Zhang Yongfu Ma Yang Liu Charles C.Han Ying Liu | 2022 | Bioactive Materials2022，7，6： | 1 |
| 5 | Electrospun Textile Strategies in Tendon to Bone Junction Reconstruction显示文摘The repair of tendon to bone junction(TBJ)remains a tremendous challenge in tissue engineering due to the complicated structure,components,mechanical properties,and cell types.In order to reconstruct the tissue and restore its functionality,biomedical scaffolds with hierarchical and gradient structures have been fabricated by various strategies.In recent decades,electrospinning has become one of the most popular methods in fabricating TBJ scaffolds due to easy fabrication,high porosity,and ECM-like nano-scale structure.However,mechanical properties are the pain point of electrospun biomedical scaffolds.Traditional textile technology can be exploited to compensate for this weakness,which will be deeply discussed here.This review will start with a brief introduction to the structure and function of the native TBJ tissue and a short overview of electrospinning technology.Then,different electrospun biomedical scaffolds for TBJ repair will be summarized and compared.Furthermore,some advanced technologies and modification methods in fabricating functionalized electrospun TBJ scaffolds are discussed.In the end,current challenges and solutions are being proposed,which would provide instruction for the research of electrospun textile TBJ scaffolds. | Xiaoyun Xu Yifan Si Yi Zhao Qinfei Ke Jinlian Hu | 2023 | Advanced Fiber Materials2023，5，3： | 0 |
| 6 | Living Electrospun Short Fibrous Sponge via Engineered Nanofat for Wound Healing显示文摘Living cells and active factors are the two core elements of tissue repair,directly affecting the healing efficiency of damaged tissue.Nanofat(NF)can release living cells,such as adipose-derived stem cells(ADSCs),as well as active growth factors to promote angiogenesis,thus realizing cell-based wound healing.Herein,a novel living electrospun short fibrous sponge is constructed by modifying three-dimensional(3D)bionic short fibers with engineered NF.The uniform distribution of the polydopamine(PDA)modification endows the living sponges with stable mechanical properties,reversible water absorption and excellent adhesion even after repeated compression by an external force and long-term aqueous immersion.Meanwhile,the living electrospun short fibrous sponges with uniform NF modification contain living cells such as ADSCs and active growth factors such as vascular endothelial growth factor(VEGF),which can effectively promote the tube formation of human umbilical vein endothelial cells(HUVECs).In vivo,the living sponges can effectively and continuously act on wounds and act as a bionic living skin to prevent the loss of internal nutrients,creating a comfortable and favorable microenvironment for tissue regeneration and promoting the healing of diabetic wounds.Therefore,living electrospun short fibrous sponges via engineered NF are expected to achieve continuous wound healing with in situ living cells and active factors in injured tissues. | Xiaohan Fu Juan Wang Dejian Qian Zhaowen Chen Liang Chen Wenguo Cui Yan Wang | 2023 | Advanced Fiber Materials2023，5，3： | 0 |
| 7 | Gallic Acid/2-Hydroxypropyl-β-cyclodextrin Inclusion Complexes Electrospun Nanofibrous Webs:Fast Dissolution,Improved Aqueous Solubility and Antioxidant Property of Gallic Acid显示文摘Gallic acid(GA)is a kind of natural polyphenolic compound,but its low aqueous solubility restricts its application in the fields of food and medicine.Cyclodextrin can form inclusion complexes with guest molecules(e.g.,essential oils,food supplements)through cavities with special properties to improve aqueous solubility,thermal stability,and bioavailability of guest molecules.In this research,gallic acid/2-hydroxypropyl-β-cyclodextrin inclusion complexes(GA/2-HP-β-CD/ICs)were formed in a highly concentrated solution of 2-HP-β-CD.Bead-free and uniform nanofibrous webs(GA/2-HP-β-CD/IC-NWs)were produced successfully by electrospun GA/HP-β-CD/IC aqueous solution.The initial molar ratio(GA:2-HP-β-CD=1:1)of GA/2-HP-β-CD/IC in the solutions was largely maintained in GA/2-HP-β-CD/IC-NW.The aqueous solubility of GA was enhanced and GA/2-HP-β-CD/IC-NW has displayed fast dissolution property.Furthermore,in comparison with GA powder,GA/2-HP-β-CD/IC-NW demonstrated improved antioxidant capacity.The results suggested that GA/2-HP-β-CD/IC-NW have broad application prospects as orally fast dissolution systems for food supplements. | SONG Yudong HUANG Hui HE Dayong YANG Mei WANG Hao ZHANG Hao LI Jiali LI Yongxin WANG Ce | 2021 | Chemical Research in Chinese Universities2021，37，3： | 0 |
| 8 | Preparation and Properties of Electrospun Sheath-core Modified-PMMA Nanofibers with Photoluminescence and Photochromic Functions显示文摘Multi-functional nanofibers are playing an important role in the optical field,and are widely used in fluorescence indication,product anti-counterfeit identification and smart clothing.Nanofibers with photoluminescence and photochromic functions are already attracting more interest from researchers.In this work,based on electrospun technology,the modified-PMMA nanofibers[PMMA=poly(methyl methacrylate)]with photoluminescence and photochromic functions were prepared through the design of the sheath-core structure(SCNFs 1-4).Compared with other samples,SCNF-4 shows outstanding photoluminescence and photochromic functions.SCNF-4 can produce green light and its fluorescence intensity and fluorescence lifetime can reach 7144 a.u.and 1031.32µs,respectively.In photochromic functions,SCNF-4 can show purple in 1 min under the 365 nm ultraviolet light,and the color can be preserved for more than 4 h under the sunlight.When SCNF-4 is irradiated by far infrared light,the color of the samples can fade quickly in 40 s.Under the irradiation of ultraviolet light of different wavelengths,SCNF-4 can display multi-color fluorescence and achieve a reversible transition between white and purple.The design of the sheath-core structure realizes the complementarity of photoluminescence and photochromic functions of the electrospun modified-PMMA nanofibers,which is important to promote the wide application of multi-functional nanofibers in the optical field. | WANG Yan XI Peng SHU Dengkun MENG Shuang LIU Kai WANG Xiaoqing CHENG Bowen | 2021 | Chemical Research in Chinese Universities2021，37，3： | 0 |
| 9 | Preparation of Electrospun CdSe-Quantum-Dots-Doped Porous Films显示文摘Electrospun porous films doped with the green-synthesized CdSe quantum dots were synthesized. Glycerol was chosen to prepare the quantum dots ( QDs), with the highest quantum yield of 78.28%. Polycaprolactone (PCL) was electrospun with CdSe QDs to avoid the QDs' toxicity and improve the QDs' cytocompatibility. The electrospun QDs-doped films preserve the original QDs' fluorescence. Pores can be detected from the SEM of the films, predicting the possibility of loading drugs in the cancer therapy. The cell proliferation assay shows excellent cytocompatibility of the eletrospun CdSe-QDs-doped films. The present eletrospun CdSe- QDs-doped porous films are cytocompatibale, highly-fluorescent and ootential to load drugs in cancer therapy. | GAO Bing SHEN Chao YUAN Shuang-long ZHANG Jian-guang YANG Yun-xia MO Xiu-mei LI Hai-yan CHEN Guo-rong | 2014 | Journal of Donghua University(English Edition)2014，31，5： | 0 |
| 10 | Electrospun Nanofibers of Hydroxyapatite / Collagen / Chitosan Promote Osteogenic Differentiation of BMSCs显示文摘Bone tissue engineering, aiming at developing bone substitutes for repair and regeneration of bone defects instead of using autologous bone grafts,has attracted wide attention in the field of tissue engineering and regenerative medicine.Developing biomimetic biomaterial scaffolds able to regulate osteogenic differentiation of stem cells could be a promising strategy to improve the therapeutic efficacy.In this study, electrospun composite nanofibers of hydroxyapatite / collagen / chitosan( HAp / Col / CTS)resembling the fibrous nanostructure and constituents of the hierarchically organized natural bone,were prepared to investigate their capacity for promoting bone mesenchymal stem cells( BMSCs)to differentiate into the osteogenic lineage in the absence and presence of the osteogenic supplementation, respectively.Cell morphology,proliferation and quantified specific osteogenic protein expression on the electrospun HAp / Col / CTS scaffolds were evaluated in comparison with different controls including electrospun nanofibrous CTS,HAp / CTS and tissue culture plate.Our results showed that the nanofibrous HAp / Col / CTS scaffolds supported better spreading and proliferation of the BMSCs than other substrates( P < 0.01).Expressions of osteogenesis protein markers,alkaline phosphatase( ALP) and Col,were significantly upregulated on the HAp / Col / CTS than those on the CTS( P < 0.01) and HAp /CTS( P < 0.05) scaffolds in the absence of the osteogenic supplementation.Moreover,presence of osteogenic supplementation also proved to enhance osteogenic differentiation of BMSCs on HAp /Col / CTS scaffolds, indicative of a synergistic effect.This study highlights the potential of BMSCs / HAp / Col / CTS cell-scaffold system for functional bone repair and regeneration applications. | 谢静 娄向新 王先流 杨亮亮 张彦中 | 2014 | Journal of Donghua University(English Edition)2014，31，5： | 0 |
| 11 | Dual-bionic regenerative microenvironment for peripheral nerve repair显示文摘Autologous nerve grafting serves is considered the gold standard treatment for peripheral nerve defects;however,limited availability and donor area destruction restrict its widespread clinical application.Although the performance of allogeneic decellularized nerve implants has been explored,challenges such as insufficient human donors have been a major drawback to its clinical use.Tissue-engineered neural regeneration materials have been developed over the years,and researchers have explored strategies to mimic the peripheral neural microenvironment during the design of nerve catheter grafts,namely the extracellular matrix(ECM),which includes mechanical,physical,and biochemical signals that support nerve regeneration.In this study,polycaprolactone/silk fibroin(PCL/SF)-aligned electrospun material was modified with ECM derived from human umbilical cord mesenchymal stem cells(hUMSCs),and a dual-bionic nerve regeneration material was successfully fabricated.The results indicated that the developed biomimetic material had excellent biological properties,providing sufficient anchorage for Schwann cells and subsequent axon regeneration and angiogenesis processes.Moreover,the dual-bionic material exerted a similar effect to that of autologous nerve transplantation in bridging peripheral nerve defects in rats.In conclusion,this study provides a new concept for designing neural regeneration materials,and the prepared dual-bionic repair materials have excellent auxiliary regenerative ability and further preclinical testing is warranted to evaluate its clinical application potential. | Yanjun Guan Zhiqi Ren Boyao Yang Wenjing Xu Wenjun Wu Xiangling Li Tieyuan Zhang Dongdong Li Shengfeng Chen Jun Bai Xiangyu Song Zhibo Jia Xing Xiong Songlin He Chaochao Li Fanqi Meng Tong Wu Jian Zhang Xiuzhi Liu Haoye Meng Jiang Peng Yu Wang | 2023 | Bioactive Materials2023，，8： | 0 |
| 12 | Sulfurization accelerator coupled Fe_(1-x)S electrocatalyst boosting SPAN cathode performance显示文摘Sulfurized polyacrylonitrile(SPAN)cathode exhibits improved cycling stability in carbonate electrolytes due to the existent of-S_(x)^(2-)-(2≤n≤4)units.However,it is still challenging for SPAN to achieve higher sulfur content,superior conductivity,and faster polysulfide conversion kinetics in ether electrolytes.Herein,polyacrylonitrile(PAN),2-morpholinothiobenzothiazole(MBS),and FeCl_(3)coated reduced graphene oxide(rGO)were used to fabricate advanced sulfur cathode through electrospinning technology to address these problems.During PAN sulfuration reactions,the MBS with abundant unsaturated bonds served as the vulcanization accelerator to facilitate the formation of longer chain sulfur species(-S_(3)-/-S_(4)-)and increase the sulfur content in the SPAN electrode system.Meanwhile,Fe_(1-x)S is in situ converted from FeCl_(3),which acts as the electrocatalyst to promote Li_(2)S nucleation and decomposition reactions.As a result,the Fe_(1-x)S/SPAN/rGO electrode with high sulfur loading of 2.0 mg·cm^(-2)delivers a reversible capacity of 1122 mAh·g^(-1)at 0.1 A·g^(-1).Notably,at a large current density of 5.0 A·g^(-1),the Fe_(1-x)S/SPAN/rGO electrode still displays a high specific capacity of 924 mAh·g^(-1)with an ultra-stable cycling life over 2000 cycles.The present work provides new insights into designing of high-performance electrode materials for long-lasting Li-S batteries. | Jinlei Qin Yun Lu Rui Wang Zhizhan Li Tao Shen Deli Wang | 2023 | Nano Research2023，16，7： | 0 |
| 13 | Preparation and Properties of Poly (ethylene terephthalate) Luminescence Fibers with Multi-branched Benzoic Acid Rare Earth Complex显示文摘A new multi-branched benzoic acid rare earth complex( MBBAL-Eu( III) complex) was prepared. The advanced tested technologies were employed to characterize the composition and structure of as-prepared complex. Scanning electron microscopy( SEM) image shows that as-prepared complex has a layer structure. Transmission electron microscopy( TEM) image presents that the shape of MBBAL-Eu( III) complex is similar to oval; the size is in the range of 20-50 nm. The thermogravimetric analysis( TGA) curves of MBBAL-Eu( III) complex reveal that as-prepared complex has good thermal stability. The PET luminescence fibers with MBBAL-Eu( III) complex were prepared through meltspinning and electrospun methods. The results prove that asprepared fibers with MBBAL-Eu( III) complex have good luminescent properties and show bright red light. | 高星草 马梦姣 李葱葱 丁留山 闫旭焕 西鹏 | 2018 | Journal of Donghua University(English Edition)2018，35，4： | 0 |
| 14 | Recent Advancements on Three‑Dimensional Electrospun Nanofiber Scaffolds for Tissue Engineering显示文摘Electrospinning is widely accepted as a technique for the fabrication of nanofibrous three-dimensional(3D)scaffolds which mimic extracellular matrix(ECM)microenvironment for tissue engineering(TE).Unlike normal densely-packed two-dimensional(2D)nanofibrous membranes,3D electrospun nanofiber scaffolds are dedicated to more precise spatial control,endowing the scaffolds with a sufficient porosity and 3D environment similar to the in vivo settings as well as optimizing the properties,including injectability,compressibility,and bioactivity.Moreover,the 3D morphology regulates cellular interaction and mediates growth,migration,and differentiation of cell for matrix remodeling.The variation among scaffold structures,functions and applications depends on the selection of electrospinning materials and methods as well as on the post-processing of electrospun scaffolds.This review summarizes the recent new forms for building electrospun 3D nanofiber scaffolds for TE applications.A variety of approaches aimed at the fabrication of 3D electrospun scaffolds,such as multilay-ering electrospinning,sacrificial agent electrospinning,wet electrospinning,ultrasound-enhanced electrospinning as well as post-processing techniques,including gas foaming,ultrasonication,short fiber assembly,3D printing,electrospraying,and so on are discussed,along with their advantages,limitations and applications.Meanwhile,the current challenges and prospects of 3D electrospun scaffolds are rationally discussed,providing an insight into developing the vibrant fields of biomedicine. | Yujie Chen Xutao Dong Muhammad Shafiq Gregory Myles Norbert Radacsi Xiumei Mo | 2022 | Advanced Fiber Materials2022，4，5： | 0 |
| 15 | Electrospun Metal–Organic Framework Nanofiber Membranes for Energy Storage and Environmental Protection显示文摘Metal–organic frameworks(MOFs)are attractive in many fields due to their unique advantages.However,the practical applications of single MOF materials are limited.In recent years,a large number of MOF-based composites have been investigated to overcome the defects of single MOF materials to broaden the avenues for the practical applications of MOFs.Among them,MOF-based hybrid nanofiber membranes fabricated by electrospinning combine the advantages of polymer nanofibers and inorganic porous materials,receiving extensive attention and development in energy storage and environmental protection.This review systematically summarizes the recent progress of MOF-based hybrid nanofiber membranes prepared by electrospinning from the perspectives of preparation and application.Firstly,two main methods for preparing MOF/polymer nanofibrous membranes are discussed.Next,the applications of MOF/polymer nanofibrous membranes in energy storage and environmental protection are summarized at length.Finally,to fully tap the potential of MOF-based nanofiber membranes in more fields,the current challenges are proposed,and future research directions are discussed. | Xiaoge Liu Yi Zhang Xiaotian Guo Huan Pang | 2022 | Advanced Fiber Materials2022，4，6： | 0 |
| 16 | Adsorption properties of the double-imprinted electrospun crosslinked chitosan nanofibers显示文摘The adsorption properties of the Pb(Ⅱ)-Cd(Ⅱ) double-imprinted electrospun crosslinked chitosan nanofibers(Pd/Cd-DIECCNs) prepared by electropspinning and imprinting process for the removal of Pb(Ⅱ) and Cd(Ⅱ) from aqueous solutions were investigated. The prepared nanofibers were characterized by scanning electron microscope(SEM) analysis. Under the optimum experimental conditions, the minimum fiber average diameter was obtained 110 nm. Then the adsorption experiments were carried out to study the effect of different adsorption parameters, such as pH, the ratio between Pb(Ⅱ) and Cd(Ⅱ)in the mixed solutions, contact time, the Pd/Cd-DIECCNs dose and temperature in a batch system. The Extended Langmuir model was applied to describe the equilibrium data of Pb(Ⅱ) and Cd(Ⅱ). The maximum adsorption capacities of the Pd/Cd-DIECCNs arrived at 567 mg/g for Pb(Ⅱ) and 341 mg/g for Cd(Ⅱ), respectively. | Yan Li Mengqi Li Jie Zhang Xiaoyan Xu | 2019 | Chinese Chemical Letters2019，30，3： | 0 |
| 17 | Hippocampal Neuron-Derived Extracellular Matrix Coated Nanofibrous Scaffold for Neural Tissue Engineering显示文摘The aim of this study is to prepare poly-L-lactide(PLLA)electrospun nanofibrous scaffolds coated with hippocampal neuron-derived extracellular matrix(N-ECM)and construct a novel neural tissue engineering scaffold.Neonatal rat hippocampal neurons were seeded on PLLA nanofibers,and then decellularized to derive a cell-free extracellular matrix loaded N-ECM/PLLA modified scaffolds.The morphology and ingredients of N-ECM/PLLA were observed by scanning electron microscopy(SEM)and immunofluorescence staining respectively,and the cytocompatibility of the composite scaffolds was characterized by cell count kit-8(CCK-8)assay.The N-ECM was clearly identified loading on scaffolds when being imaged via SEM and immunofluorescence staining results showed that the N-ECM was made up of fibronectin and laminin.Most importantly,compared with tissue culture polystyrene and pure scaffolds,N-ECM/PLLA scaffolds could effectively facilitate the proliferation of rat adrenal neuroma cells(PC12 cells),indicating their better cell compatibilities.Based on the combination of N-ECM and PLLA biomaterials,the present study has fabricated a unique and versatile neural tissue engineering scaffold,offering a new thought for future neural tissue engineering. | 郜增 刘月 王冲 李月霞 施剑敏 汤赋匀 娄向新 | 2019 | Journal of Donghua University(English Edition)2019，36，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员