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Transcriptomic analysis identifies the S100 calcium-binding protein β subunit(S100B)and intercellular adhesion molecule-1(ICAM-1)as potential diagnostic biomarkers for acute cerebral infarction

查看全文 作　　者：Dan [1]Cheng;Yushuo [2]Wang;Jingna [1]Li;Yulan [1]Yao;Simiao [1]Zhang;Yunliang [1,3]Wang 高影响力作者 机构地区：[1]Department of Neurology,Second Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan 450014,China;[2]School of Medicine,Medical Sciences and Nutrition University of Aberdeen,Aberdeen AB252ZD,UK;[3]Department of Neurology,The 960th Hospital of PLA,Zibo,Shandong 255300,China高影响力机构 出　　处：《Genes & Diseases》索引2024年第11卷第1期,共3页高影响力期刊 摘　　要：Due to its high mortality,disability,and recurrence rates,cerebral infarction has a serious impact on the economy and is a physical and psychological burden on patients.1 There is a huge unmet medical need for biomarkers to predict acute cerebral infarction.Studies have shown that the ischemic damage to neurons,myelin,and glia caused by a stroke leads to the release of the S100 calcium-binding protein beta subunit(S100B)through the blood-brain barrier into the systemic circulation,resulting in an increase in the level of S100B in the peripheral blood. 关 键 词：S100B CEREBRAL INFARCTION
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