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| 1 | Seven microcystins from Microcystis waterbloom in Lake Dalai,China显示文摘Seven types of microcystins,isolated from Microcystis waterbloom in Lake Dalai,were characterized.The major toxins:MCYST-LR,MCYST-RR,[D-Asp3]MCYST-LR and[Dha7]MCYST-LR were identified by high performance liquid chromatography(HPLC),as com-pared with the authentic microcystins.The minor toxins:MCYST FR,[L-Mser7]MCYST-LRand an unknown MCYST which was most likely to be MCYST-(H4)YR were identified with frit-fast atom bombardment liquid chromatography/mass spectrometry(Frit-FAB LC/MS)and aminoacid analysis.The toxigenic diversity in blue-green algae(cyanobacteria)was discussed. | He Zhenrong He Jiawan Yu Minjuan Institute of Hydrobiology,Chinese Academy of Sciences,Wuhan 430072,ChinaQiao Mingye Shen Zhi Wu Liandi Inner Mongolia Environmental Science Research Instìtute,Huhehote 010010,ChinaWu Suozhu Guo Yunfeng Hulunbeer League Environmental Monitoring Station,Inner Mogolia 021008,ChinaFumio Kondo Aichi Prefectural Institute of Public Health,Tsuji-machi,Kita-ku,Nagoya 462,JapanKen-ichi Harada Faculty of Pharmacy,Meijo University,Tempaku,Nagoya 468,Japan | 1997 | Journal of Environmental Sciences1997，9，1： | 6 |
| 2 | Surface Activities of Calix [4]resorcinarenes Bearing Four Hydrophobic Chains and Its Solubilization for Organic Compounds显示文摘Calix resorcinarenes bearing four hydrophobic side chains ( Ar-Rn, Ar-Ph, and Ar-N) orient stably on water oil interface and show high solubilization capacities for organic compounds, such as long chain alcohols, benzene, toluene and dyes. The capacities are high even near the cmc of polyalkylated calix resorcinarenes, but the solubilities of organic compounds(solubilizates) decrease with the increase of the size of the solubilizates. Ar-R 6, with a chain length of six carbons, is the most effective among Ar-R n , Ar-Ph, and Ar-N; 11 fold mol of hexanol is dissolved in 2×10 -3 mol/L Ar-R 6. Moreover, Ar-R n bearing four alkyl side chains solubilizes the chain alcohols of the same chain length mostly. The solubilization capacities are presumably brought by inclusion in a large cavity of the polyalkylated calix resorcinarenes and by an efficient orientation of the solubilizates. | LI Bo *1 , Yoshifumi KOIDE 1 and Kunio ESUMI 21. Toyota Central R & D Labs., Inc., 41 1, Yokomichi, Nagakute, Aichi 480 1192, Japan 2. Departemnt of Applied Chemistry and Institute of Colloid and Interface Science, Science University of Tokyo | 2002 | Chemical Research in Chinese Universities2002，18，2： | 3 |
| 3 | Chemotherapy of cerebral gliomas directed by the chemosensitivity test in vitro: a clinical study显示文摘Objective: To evaluate correlation between chemosensitivity of tumor cells in vitro and their clinical responsive- ness in vivo by comparing the difference of curative effect between chemotherapy of cerebral gliomas directed by chemo- sensitivity test in vitro and its routine chemotherapy. Methods: Sixty-two patients with cerebral gliomas were recruited as the experiment group, who had received total resection or subtotal resection of the tumor. The resected tumor cells were cultured in vitro, followed by chemosensitivity test using colorimetric MTT assay. Finally, chemotherapeutic protocol was made based on the results of the chemosensitivity test. Fifty patients with cerebral gliomas subjected to the routine chemotherapeutic protocol were simultaneously recruited as the control group, whose age, gender, survival functional status and operational fashion were matched with the experiment group. The two groups were equally followed up for the survival functional status, recurrence and death. All data were analyzed using SPSS 10.0 software. Results: At the time of evaluation, KPS values of 64.52 ± 35.84 were seen in the experiment group, and 33.60 ± 36.24 in the control group, showing statistical difference between the two groups (t = 4.5163, P = 0.000). During 2–4 years of follow up, a recurrence rate of 32.26% was seen in the experimental group, and 60.00% in the control group, showing a statistical difference between the two groups (χ2 = 8.620, P = 0.003). The fatality was 22.58% in the experiment group, and 48.00% in the control group, showing a statistical difference between the two groups (χ2 = 7.978, P = 0.005). The survival rate of the experimental group was higher than that of the control group, showing a statistical differences between the two groups (χ2 = 7.29, P = 0.0069). Conclusion: Chemotherapy of glio- mas under the guidance of chemosensitivity test in vitro contributes to obvious improvement on the current survival functional status, a clear decline of the recurrence rates and fatality rate, and raised survival rates of the patients. A close correlation between the chemosensitivity in vitro and clinical responsiveness in vivo is observed. | Chaochun Yu Fanmin Zhou Yuqian Wang Ping Zhong Guanfu Jiang Aichi Miao Hao Lu | 2007 | The Chinese-German Journal of Clinical Oncology2007，6，3： | 2 |
| 4 | Database for catalysis design显示文摘 | Ito T Hamata H Kint aichi Y | 1991 | Catal Today1991，10，2： | 1 |
| 5 | A protocol for Agrobacterum-mediated transformation in rice显示文摘 | Nishimura A Aichi I Matsuoka M | 2006 | Nature protocols2006，1，6： | 1 |
| 6 | Central Japan显示文摘 | Noro H C Komaki City Aichi Prefecture | 1986 | Miner1986，，21： | 1 |
| 7 | Effects of human activities and urbanization on groundwater environments: An example from the aquifer system of Tokyo and the surrounding area显示文摘 | Takeshi Hayashi Tomochika Tokunaga Masaatsu Aichi Jun Shimada Makoto Taniguchi | 2008 | Science of the Total Environment2008，，9： | 1 |
| 8 | Effects of human activities and urbanization on groundwater environments: An example from the aquifer system of Tokyo and the surrounding area 显示文摘 | HAYASHIH T TKUNAGA T AICHI M | 2008 | Science of the Total Environment2008，7，12： | 1 |
| 9 | Fluid shear stress-induced cyclooxygenase-2 expression is mediated by C/EBP b, cAMP-response element-binding protein, and AP-1 in osteoblastic MC3T3-E1 cells显示文摘 | Aichi O Toshiya A Toshio K | 2001 | J Biol Chem2001，276，： | 1 |
| 10 | Estimation of threshold stress in accelerated life-testing显示文摘 | AICHI | 1993 | IEEE Transactions on Reliability1993，42，4： | 1 |
| 11 | Profile of vitiligo in the south of Tunisia显示文摘 | Akrem J Baroudi A Aichi T | 2008 | Inter J Dermatol2008，47，： | 1 |
| 12 | Characteristics of Pb-based alloy prepared by powder rolling method as an insoluble anode for zinc electrowinning 显示文摘 | Taguchi Masami Takahashi Hiroki Nagai Masaya Aichi Taro Sato Rie | 2013 | Hydrometallurgy2013，136，： | 1 |
| 13 | Synthesis of Highly ordered Large Size Mesoporous Silica and Effect of Stabilization as Enzyme Supports in Organic Solvent显示文摘FSM 16, MCM 41 and SBA 15 types of hexagonal mesoporous silica with a highly ordered 2 dimensional structure were synthesized by using different silicon sources and surfactants. In the 2 dimensional silicate framework, pore size can be uniformly controlled by the combined use of the surfactants having different alkyl chain lengths and the swelling agents(triisopropyl benzene). The pore diameter of FSM 16 and MCM 41 can be expanded to be 10 nm, SBA 15 to be 15 nm. The crystal regularity was decreased with the increase of the pore diameter. In FSM 16 derived from kanemite(silicon source) and MCM 41 from water glass, their anionic characteristics on the pore wall may be stronger than those of SBA 15 derived from oligomeric tetramethoxysilane(TMOS). We have successfully used FSM 16 and MCM 41 to immobilize the enzyme having cationic residues below isoelectric point. The level of adsorption of enzymes in FSM 16 and MCM 41 was relatively high, but was low in SBA 15 support. The mechanism of enzyme to be adsorbed in mesoporous silica was suggested to be the ionic interactions. In aqueous solutions, horseradish peroxidase(HTP) was immobilized in FSM 16 with 8.9 nm mesopores and the highest loading amount(183 mg/mg FSM) was obtained, but for the FSM 16 of pore diameter 30 nm only an amount of 28 mg/mg FSM was obtained. The catalytic activity in the organic solvent was high when HRP was immobilized in FSM 16 and MCM 41, but it was low in case of SBA 15. | LI Bo * , Inagaki S., Miyazaki C. and Takahashi H.Toyota Central R & D Labs., Inc., 41 1, Yokomichi, Nagakute cho, Aichi 480 1192, Japan | 2002 | Chemical Research in Chinese Universities2002，18，2： | 1 |
| 14 | Serum alpha-fetoprotein-positive gastric carcinoid with liver metastasis显示文摘 | Hiroshi Mori Morikazu Onji Aichi Yoshida Ryo Fukunishi | 1980 | Virchows Archiv A Pathological Anatomy and Histology1980，，1： | 1 |
| 15 | A protocol for Agrobacterium-mediated transformation in rice显示文摘 | Nishimura A Aichi I Matsuoka M | 2006 | Nature Protocols2006，1，6： | 1 |
| 16 | Profile of vitiligo in the south of Tunisia显示文摘 | Akrem J Baroudi A Aichi T | 2008 | Int J Dermatol2008，47，7： | 1 |
| 17 | A protocol for Agrobacterium-mediated transformation in rice显示文摘 | Nishimura A Aichi I Matsuoka M | 2006 | Nat Protoc2006，1，6： | 1 |
| 18 | Effects of human activities and urbanization on groundwater environments: example from the aquifer system of Tokyo and the surrounding area 显示文摘 | HAYASHI T TOKUNAGA T AICHI M | 2009 | Science of the Total Environment2009，407，9： | 1 |
| 19 | Apatite phosphate doped by cobalt as hight efficient catalyst of multi-component synthesis of therapeutic spiropyrimidine compound显示文摘Spiropyrimidines vanquish a significant situation in the field of heterocyclic chemistry, they are broadly utilized as an antibacterial, an inhibitor of multidrug opposition, or an antiplatelet and antithrombotic drug. Phosphate, the principal Moroccan mineral wealth occupies a vital spot in the economic sector and its valuation is a goal continually looked for. Among the conceivable outcomes of valorization, its utilization in heterogeneous catalysis which thought about an exceptionally encouraging new way. In this context, the focus on the reaction of the synthesis of spiropy-rimidine, catalyzed by natural phosphate (NP) and by fluoroapatite (Fap), are used alone or doped by cobalt. These phosphate catalysts were characterized by XRD, IR and SEM, while the synthesized spiropyrimidine was identified by IR, GC-MS and NMR. The obtained yield with fluorapatite doped by cobalt (Co/Fap), at room temperature in ethanol is very high and shows a high impact performance induced by a synergistic effect compared to that of NP alone. | Abdallah Rhihil Youness Aichi Mohamed Zahouily Saïd Sebti Mohamed El Guendouzi | 2022 | Natural Products and Bioprospecting2022，12，1： | 0 |
| 20 | 镍钛形状记忆合金的变形性能与马氏体及R相转换的相关性显示文摘为描述TiNi形状记忆合金马氏体式转换和R相转换引起的形状记忆效应和伪弹性,在综合考虑与上述两个变化相关的诱导相体积变化的基础上,推导了一个热力学本构方程。该方程能很好地表达形状记忆效应,伪弹性和回复应力。 | Pinghua Lin Hisaaki Tobushi Akira Ikai Kikuaki Tanakan(Department of Mechanical Engineering,Southeast University,Nanjing)(Department of Mechaniical Engineering, Aichi Institute of Technology Yagusa-cho, Toyota,Japan)(Department of Aerospace Engineering, T | 1995 | 医用生物力学1995，10，2： | 0 |
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