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| 1 | 卒中或短暂性脑缺血发作患者的卒中预防指南 美国心脏协会/美国卒中协会为医疗卫生专业人员制定的指南显示文摘本指南旨在为缺血性卒中或短暂性脑缺血发作存活患者的卒中预防提供全面和及时的循证推荐,包括危险因素的控制、动脉粥样硬化性疾病的于预、心源性栓塞的抗栓治疗以及非心源性栓塞性卒中的抗血小板治疗。另外,还对其他许多特殊情况下的复发性卒中预防提供了推荐意见,包括动脉夹层分离、卯圆孔未闭、高同型半胱氨酸血症、高凝状态、镰状细胞病、脑静脉窦血栓形成、女性卒中(尤其是与妊娠和绝经后雌激素替代治疗相关性卒中)、脑出血后抗凝药的使用等,以及实施本指南及其在高危人群中应用的特定方法。 | Karen L. Furie Scott E. Kasner Robert J. Adams Gregory W. Albers Ruth L. Bush Susan C. Fagan Jonathan L. Halperin S. Claiborne Johnston Irene Katzan Walter N. Kernan Pamela H. Mitchell Bruce Ovbiagele Yuko Y. Palesch Ralph L. Sacco Lee H. Schwamm Sylvia Wassertheil-Smoller Tanya N. Turan Deidre Wentworth 李海峰(译) 刘涛(译) 杨潘(译) 王鹏(译) | 2011 | 国际脑血管病杂志2011，19，1： | 391 |
| 2 | Retrospective study on mixed neuroendocrine non-neuroendocrine neoplasms from five European centres显示文摘BACKGROUND Mixed neuroendocrine non-neuroendocrine neoplasm(MiNEN)is a rare diagnosis,mainly encountered in the gastro-entero-pancreatic tract.There is limited knowledge of its epidemiology,prognosis and biology,and the best management for affected patients is still to be defined.AIM To investigate clinical-pathological characteristics,treatment modalities and survival outcomes of a retrospective cohort of patients with a diagnosis of MiNEN.METHODS Consecutive patients with a histologically proven diagnosis of MiNEN were identified at 5 European centres.Patient data were retrospectively collected from medical records.Pathological samples were reviewed to ascertain compliance with the 2017 World Health Organisation definition of MiNEN.Tumour responses to systemic treatment were assessed according to the Response Evaluation Criteria in Solid Tumours 1.1.Kaplan-Meier analysis was applied to estimate survival outcomes.Associations between clinical-pathological characteristics and survival outcomes were explored using Log-rank test for equality of survivors functions(univariate)and Cox-regression analysis(multivariable).RESULTS Sixty-nine consecutive patients identified;Median age at diagnosis:64 years.Males:63.8%.Localised disease(curable):53.6%.Commonest sites of origin:colon-rectum(43.5%)and oesophagus/oesophagogastric junction(15.9%).The neuroendocrine component was;predominant in 58.6%,poorly differentiated in 86.3%,and large cell in 81.25%,of cases analysed.Most distant metastases analysed(73.4%)were occupied only by a poorly differentiated neuroendocrine component.Ninety-four percent of patients with localised disease underwent curative surgery;53%also received perioperative treatment,most often in line with protocols for adenocarcinomas from the same sites of origin.Chemotherapy was offered to most patients(68.1%)with advanced disease,and followed protocols for pure neuroendocrine carcinomas or adenocarcinomas in equal proportion.In localised cases,median recurrence free survival(RFS);14.0 months(95%CI:9.2-24.4),and median overall survival(OS):28.6 months(95%CI:18.3-41.1).On univariate analysis,receipt of perioperative treatment(vs surgery alone)did not improve RFS(P=0.375),or OS(P=0.240).In advanced cases,median progression free survival(PFS);5.6 months(95%CI:4.4-7.4),and median OS;9.0 months(95%CI:5.2-13.4).On univariate analysis,receipt of palliative active treatment(vs best supportive care)prolonged PFS and OS(both,P<0.001).CONCLUSION MiNEN is most commonly driven by a poorly differentiated neuroendocrine component,and has poor prognosis.Advances in its biological understanding are needed to identify effective treatments and improve patient outcomes. | Melissa Frizziero Xin Wang Bipasha Chakrabarty Alexa Childs Tu V Luong Thomas Walter Mohid S Khan Meleri Morgan Adam Christian Mona Elshafie Tahir Shah Annamaria Minicozzi Wasat Mansoor Tim Meyer Angela Lamarca Richard A Hubner Juan W Valle Mairéad G McNamara | 2019 | World Journal of Gastroenterology2019，25，39： | 13 |
| 3 | Guidelines for the Prevention of Stroke in Patients With Stroke or Transient Ischemic Attack: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | Karen L. Furie Scott E. Kasner Robert J. Adams Gregory W. Albers Ruth L. Bush Susan C. Fagan Jonathan L. Halperin S. Claiborne Johnston Irene Katzan Walter N. Kernan Pamela H. Mitchell Bruce Ovbiagele Yuko Y. Palesch Ralph L. Sacco Lee H. Schwamm Sylvia W | 2011 | Stroke2011，，1： | 8 |
| 4 | Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial显示文摘 | David W Andrews Charles B Scott Paul W Sperduto Adam E Flanders Laurie E Gaspar Michael C Schell Maria Werner-Wasik William Demas Janice Ryu Jean-Paul Bahary Luis Souhami Marvin Rotman Minesh P Mehta Walter J Curran | 2004 | The Lancet . 2004 (9422)2004，，9422： | 2 |
| 5 | Guidelines for the Prevention of Stroke in Patients With Stroke or Transient Ischemic Attack: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | Karen L. Furie Scott E. Kasner Robert J. Adams Gregory W. Albers Ruth L. Bush Susan C. Fagan Jonathan L. Halperin S. Claiborne Johnston Irene Katzan Walter N. Kernan Pamela H. Mitchell Bruce Ovbiagele Yuko Y. Palesch Ralph L. Sacco Lee H. Schwamm Sylvia W | 2011 | Stroke2011，，1： | 2 |
| 6 | Long‐term fire history in northern Quebec: implications for the northern limit of commercial forests显示文摘 | France Oris Hugo Asselin Walter Finsinger Christelle Hély Olivier Blarquez Marie‐Eve Ferland Yves Bergeron Adam A. Ali | 2014 | J Appl Ecol2014，，3： | 1 |
| 7 | Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans显示文摘 | Mark J. Graham Richard G. Lee Thomas A. Bell Wuxia Fu Adam E. Mullick Veronica J. Alexander Walter Singleton Nick Viney Richard Geary John Su Brenda F. Baker Jennifer Burkey Stanley T. Crooke Rosanne M. Crooke | 2013 | Circulation Research2013，，11： | 1 |
| 8 | Teaching Communication Skills: Using Action Methods to Enhance Role-Play in Problem-Based Learning 显示文摘 | Walter F Baile Adam Blatner | 2014 | Journal of the Society for Simulation in Heahhcare2014，9，4： | 1 |
| 9 | Additional genetic abnormalities significantly worsen poor prognosis associated with 1q21 amplification in multiple myeloma patients显示文摘 | Norbert Grzasko Marek Hus Andrzej Pluta Artur Jurczyszyn Adam Walter‐Croneck Marta Morawska Sylwia Chocholska Roman Hajek Anna Dmoszynska | 2012 | Hematol Oncol2012，，1： | 1 |
| 10 | Guidelines for the Prevention of Stroke in Patients With Stroke or Transient Ischemic Attack: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | Karen L. Furie Scott E. Kasner Robert J. Adams Gregory W. Albers Ruth L. Bush Susan C. Fagan Jonathan L. Halperin S. Claiborne Johnston Irene Katzan Walter N. Kernan Pamela H. Mitchell Bruce Ovbiagele Yuko Y. Palesch Ralph L. Sacco Lee H. Schwamm Sylvia W | 2011 | Stroke2011，，1： | 1 |
| 11 | Refugees in Europe 显示文摘 | Walter Adams | 1939 | Annals of the American Academy of Political and Social Science1939，，： | 1 |
| 12 | Mobile stroke care expedites intravenous thrombolysis and endovascular thrombectomy显示文摘Background The number of mobile stroke programmes has increased with evidence,showing they expedite intravenous thrombolysis.Outstanding questions include whether time savings extend to patients eligible for endovascular therapy and impact clinical outcomes.Objective Our mobile stroke unit(MSU),based at an academic medical centre in upstate New York,launched in October 2018.We reviewed prospective observational data sets over 26 months to identify MSU and non-MSU emergency medical service(EMS)patients who underwent intravenous thrombolysis or endovascular thrombectomy for comparison of angiographic and clinical outcomes.Results Over 568 days in service,the MSU was dispatched 1489 times(2.6/day)and transported 300 patients(20%of dispatches).Intravenous tissue plasminogen activator(tPA)was administered to 57 MSU patients and the average time from 911 call-to tPA was 42.5 min(±9.2),while EMS transported 73 patients who received tPA at 99.4 min(±35.7)(p<0.001).Seven MSU patients(12%)received tPA from 3.5 hours to 4.5 hours since last known well and would likely have been outside the window with EMS care.Endovascular thrombectomy was performed on 21 MSU patients with an average 911 call-to groin puncture time of 99.9 min(±18.1),while EMS transported 54 patients who underwent endovascular thrombectomy(ET)at 133.0 min(±37.0)(p=0.0002).There was no difference between MSU and traditional EMS in modified Rankin score at 90-day clinic follow-up for patients undergoing intravenous thrombolysis or endovascular thrombectomy,whether assessed as a dichotomous or ordinal variable.Conclusions Mobile stroke care expedited both intravenous thrombolysis and endovascular thrombectomy.There is an ongoing need to show improved functional outcomes with MSU care. | Matthew T Bender Thomas K Mattingly Redi Rahmani Diana Proper Walter A Burnett Jason L Burgett Joshua LEsperance Jeremy T Cushman Webster H Pilcher Curtis G Benesch Adam G Kelly Tarun Bhalla | 2022 | Stroke & Vascular Neurology2022，7，3： | 1 |
| 13 | Effect of olanzapine on cognition during treatment of behavioral and psychiatric symptoms in patients with dementia: a post‐hoc analysis显示文摘 | Walter G.Deberdt AlanSiegal JonnaAhl Adam L.Meyers RonaldLandbloom | 2008 | Int. J. Geriat. Psychiatry2008，，4： | 1 |
| 14 | Guidelines on the Diagnosis and Management of Acute Pulmonary Embolism显示文摘 | Adam Torbicki Arnaud Perrier Stavros Konstantinides Giancarlo Agnelli Nazzareno Galiè Piotr Pruszczyk Frank Bengel Adrian J.B. Brady Daniel Ferreira Uwe Janssens Walter Klepetko Eckhard Mayer Martine Remy-Jardin Jean-Pierre Bassand | 2008 | 2008，，12： | 1 |
| 15 | Steel imports and vertical oligopoly power显示文摘 | DIRLAM JOEL B | 1964 | American Economic Review1964，54，5： | 1 |
| 16 | Use of a falciformligament pedicle flap to decrease pancreatic fistula after distal pan-createctomy 显示文摘 | Walters DM Stokes JB Adams RB | 2011 | Pancreas2011，40，4： | 1 |
| 17 | Disease management projects and the Chronic Care Model in action: baseline qualitative research显示文摘 | Walters BH Adams SA Nieboer AP | 2012 | BMC Health Serv Res2012，12，： | 1 |
| 18 | Major Dietary Protein Sources and Risk of Coronary Heart Disease in Women显示文摘 | Adam M. Bernstein Qi Sun Frank B. Hu Meir J. Stampfer JoAnn E. Manson Walter C. Willett | 2010 | Circulation2010，，9： | 1 |
| 19 | Use of a falciform ligament pedicle flap to decrease pancreatic fistula after distal pancreatectomy 显示文摘 | Walters DM Stoke JB Adams RB | 2011 | Pancreas2011，40，4： | 1 |
| 20 | Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial显示文摘 | David W Andrews Charles B Scott Paul W Sperduto Adam E Flanders Laurie E Gaspar Michael C Schell Maria Werner-Wasik William Demas Janice Ryu Jean-Paul Bahary Luis Souhami Marvin Rotman Minesh P Mehta Walter J Curran | 2004 | The Lancet2004，，9422： | 1 |
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