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| 1 | Accuracy of transnasal endoscopy with a disposable esophagoscope compared to conventional endoscopy显示文摘AIM: To assess feasibility of unsedated esophagoscopy using a small-caliber disposable transnasal esophagosco-py and to compare its accuracy with standard endoscopy.METHODS: We prospectively included subjects who were referred for upper endoscopy. All subjects un-derwent transnasal endoscopy with E.G. Scan^(TM). The disposable probe has a 3.6 mm gauge and at its distal end there is a 6 mm optical capsule, with a viewing angle of 125°. Patients underwent conventional endos-copy after the completion of E.G. Scan^(TM). We describe the findings detected by the E.G. Scan^(TM) and calculate the diagnostic accuracy, sensitivity, specificity, positive predictive value, negative predictive value and Kappa index for esophageal diagnosis.RESULTS: A total of 96 patients(54 women), mean age of 50.12 years(14 to 79), were evaluated. In all cases we were able to perform esophagoscopy with E.G.Scan^(TM). The average realization time was 5 min. A total of 58 alterations were detected in the esophagus, 49 gastric abnormalities and 13 duodenal abnormalities. We found that for esophageal varices, E.G. Scan^(TM) has sensitivity, specificity and diagnostic accuracy of 95%, 97% and 97%, respectively. Kappa coefficients were 0.32 for hiatal hernia, 0.409 for erosive gastroesopha-geal reflux disease, 0.617 for Barrett's esophagus, and 0.909 for esophageal varices.CONCLUSION: Esophagoscopy with E.G. Scan? is a well-tolerated, fast and safe procedure. It has an ap-propriate diagnostic accuracy for esophageal varices when compared with conventional endoscopy. | María R Aedo Miguel Zavala-González Arturo Meixueiro-Daza José María Remes-Troche | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，4： | 3 |
| 2 | Bacterial lipopolysaccharide induces rainbow trout myotube atrophy via Akt/FoxO1/Atrogin-1 signaling pathway显示文摘Lipopolysaccharide (LPS ) 由于内毒素的骨胳的肌肉房间识别和分解代谢的发信号的小径的作为结果的激活在更高的脊椎动物被看作肌肉萎缩的强大的 inducer。相反,没有直接在更低的脊椎动物导致骨胳的肌肉萎缩的 LPS 的证据,例如鱼。多年,鱼对 LPS 抵抗,这被假定,主要由于在表明小径的像使用费的受体(TLR ) 的特色的差别什么时候与哺乳动物相比。在这研究,我们报导有教养的彩虹鳟鱼(Oncorhynchus mykiss ) 的刺激有 LPS (100 ng/ml ) 的 myotubes 在 pAkt/Akt 比率,在 pFoxO1/FoxO1 比率的随后的减小,和 atrogin-1 的重要增加导致了短暂减少抄本表示。有多粘菌素 B,一个抵销 LPS 代理人,和 740 Y-P 的 Preincubation, p85-PI3K 的收缩筋,堵住了 LPS 的效果。另外, LPS 处理在 myotube 直径在蛋白质 ubiquitination 和减小导致了增加,哪个与没在多粘菌素 B 和 740 个 Y-P 预告的处理下面被观察的肌肉发达的萎缩被联系。最后,彩虹鳟鱼 myotubes 表示了基因 tlr1, tlr3, tlr5m, tlr8a1, tlr8a2, tlr9,和 tlr22,与在 LPS 刺激下面的 tlr5m 和 tlr9 的显著地增加的表情。这些结果显示 LPS 是 inducer 捞骨胳的肌肉萎缩并且建议 TLR5M 和 TLR9 可以在检测 LPS 起重要作用,它第一次支持 LPS 是在 teleost 的骨胳的肌肉萎缩的直接 inducer 的假设种类。 | J.E. Aedo A.E. Reyes R. Avendano-Herrera A. Molina J.A. Valdesl | 2015 | Acta Biochimica et Biophysica Sinica2015，47，11： | 2 |
| 3 | Detection and typification of human papilloma virus in pre cancerous cervical lesions 显示文摘 | Aedo AS Melo AA Garcia P | 2007 | Rev Med Chil2007，135，： | 1 |
| 4 | Group recruitment and early survival of Mazzaella Laminarioides 显示文摘 | Santelices B Aedo D | 2006 | J Appl Phycol2006，18，： | 1 |
| 5 | Obesity and its re- lation to depressive symptoms and sedentary lifestyle in middle-aged women 显示文摘 | Bliarnel JE Chedraui P Aedo S | 2015 | Maturitas2015，80，1： | 1 |
| 6 | A bank of microscopic forms on disturbed boulders and stones in tide pools显示文摘 | SANTELICES B HOFFMANN A J AEDO D | 1995 | Marine Ecology Progress Series1995，129，： | 1 |
| 7 | Gastric evacuation of the redspotted catshark under laboratory conditions 显示文摘 | AEDO G ARANCIBIA H | 2001 | Journal of Fish Biology2001，58，5： | 1 |
| 8 | End - user oriented strategies to facilitate multi - organizational adoption of e- mergency management information systems 显示文摘 | Aedo I Paloma D P John M C | 2010 | Informa- tion Processing dr Management2010，46，1： | 1 |
| 9 | Relative banding affinity of various progestins and antiprogestins to a rabbit myometrium receptor显示文摘 | Boonkasemsanti W Aedo AR Cekan SZ | 1989 | Arzneimittelforschung1989，39，2： | 1 |
| 10 | Fieldtesting of inter-and intraspecific coalescence among midintertidalred algae显示文摘 | SANTELICES B AEDO D HORMAZáBAL M 2003 | 2003 | Mar Ecol Prog Ser2003，250，： | 1 |
| 11 | Induction of labor with mifepristone--a randomized,double-blind study versus placebo显示文摘 | Stenlund PM Ekman G Aedo AR | 1999 | Acta Obstet Gynecol Scand1999，78，： | 1 |
| 12 | Patulous eustachian tube in bariatric surgery patients显示文摘 | Muiioz Df Aedo C Der C | 2010 | Otolaryngol Head Neck Surg2010，143，4： | 1 |
| 13 | End-User Oriented Strategies To Facilitate Multi-Organizational Adoption Of Emergency Management Information Sys- tems 显示文摘 | Aedo Ignacio Diaz Paloma Carroll John M | 2011 | Information Processing & Management2011，46，1： | 1 |
| 14 | The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance显示文摘 | Oscar Tapia Ismael Riquelme Pamela Leal Alejandra Sandoval Susana Aedo Helga Weber Pablo Letelier Enrique Bellolio Miguel Villaseca Patricia Garcia Juan Carlos Roa | 2014 | Virchows Archiv2014，，1： | 1 |
| 15 | Assays of antibodies to a C-terminal peptide or the entire β -subunit of human chorionic gonadotropin 显示文摘 | Cekan SZ Aedo AR | 1998 | J Clin Lab Anal1998，12，1： | 1 |
| 16 | Solvent inhalation (tolu- ene and n-hexane) during the brain growth spurt impairs the maturation of frontal, parietal and occipital cerebrocortical neu- rons in rats显示文摘 | Pascual R Aedo L Meneses J C | 2010 | Int J Dev Neurosci2010，28，6： | 1 |
| 17 | Studies on a vaginal ring releasing levonorgestrel at an initial rate of 27 micrograms/24 h when used alone or in combination with transdermal systems releasing estradiol显示文摘 | LANDGREN B M AEDO A R JOHANNISSON E | 1994 | Contraception1994，50，1： | 1 |
| 18 | Advanced hepatocellular carcinoma: importance of clinical tr/als显示文摘 | Aedo V Cristina V Raymond E | 2015 | Rev Med Suisse2015，11，475： | 1 |
| 19 | Knots detection in wood using microwaves显示文摘 | E Baradit R Aedo J Correa | 2006 | Wood Sci Technol2006，40，2： | 1 |
| 20 | Knots detection in wood using microwaves显示文摘 | E. Baradit R. Aedo J. Correa | 2006 | Wood Science and Technology2006，，2： | 1 |
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