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| 1 | Fracture Union in Closed Interlocking Nail in Humera Shaft Fractures显示文摘 | Ramji Lal Sahu Raini Ranjan Ajay Lal | 2015 | Chinese Medical Journal2015，，11： | 5 |
| 2 | Heart failure in COVID-19 patients:Critical care experience显示文摘Patients with heart failure(HF)may be at a higher risk of coronavirus disease 2019(COVID-19)infection and may have a worse outcome due to their comorbid conditions and advanced age.In this narrative review,we aim to study the interaction between COVID-19 and HF from a critical care perspective.We performed a systematic search for studies that reported HF and critical carerelated outcomes in COVID-19 patients in the PubMed and Medline databases.From a total of 1050 papers,we identified 26 that satisfied the eligibility criteria for our review.Data such as patient demographics,HF,intensive care unit(ICU)admission,management,and outcome were extracted from these studies and analyzed.We reported outcomes in heart-transplant patients with COVID-19 separately.In hospitalized patients with COVID-19,the prevalence of HF varied between 4%and 21%.The requirement for ICU admission was between 8%and 33%.HF patients with COVID-19 had an overall mortality rate between 20%and 40%.We identified that HF is an independent predictor of mortality in hospitalized COVID-19 patients,and patients with HF were more likely to require ventilation,ICU admission and develop complications.Patients with HF with reduced ejection fraction did worse than those with HF with midrange ejection fraction,and HF with preserved ejection fraction.COVID-19 patients with HF should be identified early and managed aggressively in an attempt to improve outcomes in this cohort of patients. | Kevin John John Ajay K Mishra Chidambaram Ramasamy Anu A George Vijairam Selvaraj Amos Lal | 2022 | World Journal of Virology2022，11，1： | 1 |
| 3 | Update on retroperitoneal hematoma in children显示文摘Dear editor,We read with great interest the recent article by Badheka et al[1]published in your esteemed journal.Hereby we would like to address few additional points related to childhood retroperitoneal hematoma(RPH).RPH can be broadly divided into two categories,trauma/procedure related or spontaneous bleeding.Similarly,there may be one or more predisposing factors contributing for RPH:chronic liver disease,chronic kidney disease,bleeding disorders,blood thinner,interventions and so on. | Kamal Kant Sahu Ajay Kumar Mishra Amos Lal | 2020 | World Journal of Emergency Medicine2020，11，1： | 1 |
| 4 | Real time fabric defect detection system on an embedded DSP platform显示文摘 | Jagdish Lal Raheja Bandla Ajay Ankit Chaudhary | 2013 | Optik-International Journal for Light and Electron Optics2013，124，21： | 1 |
| 5 | Fungal elicitor-mediated enhancement in growth and asiaticoside content of Centella asiatica L. shoot cultures显示文摘 | Archana Prasad Archana Mathur Alok Kalra Madan M. Gupta Raj K. Lal Ajay K. Mathur | 2013 | Plant Growth Regulation2013，，3： | 1 |
| 6 | Real time fabric defect detection system on an embedded DSP platform 显示文摘 | Raheja J Lal Ajay B Chaudhary A | 2013 | Optik2013，124，： | 1 |
| 7 | Utility of cardiac bioenzymes in predicting cardiovascular outcomes in SARS-CoV-2显示文摘BACKGROUND Cardiovascular complications have been increasingly recognized in the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)associated coronavirus disease 2019(COVID-19).Cardiac biomarkers are released because of this ongoing cardiovascular injury and can act as surrogate markers to assess the disease severity.AIM To review the variation and utility of these biomarkers in COVID-19 to ascertain their role in diagnosis,prognosis and clinical outcomes of the disease.METHODS We performed a literature search in PubMed,Medline and the Reference Citation Analysis(RCA),using the search terms“COVID-19”and“cardiac bioenzymes”or“cardiac biomarkers”.Additionally,we also used the latest reference citation analysis tool to identify more articles.RESULTS Cardiac troponin has been consistently elevated in patients with COVID-19 associated myocarditis,and strongly correlated with adverse prognosis.Natriuretic peptides including brain natriuretic peptide(BNP)and pro-BNP is elevated in patients with COVID-19 associated cardiac injury,irrespective of their prior heart failure status,and independently correlated with worst outcomes.Alongside these traditional biomarkers,novel cardiac bioenzymes including presepsin,soluble ST2 and copeptin,are also increasingly recognized as markers of cardiovascular injury in COVID-19 and can be associated with poor outcomes.CONCLUSION Assessment of cardiac bioenzymes at admission and their serial monitoring can help assess the severity of disease and predict mortality in patients with SARS-CoV-2 infection.Future studies are needed to elude the critical importance of novel biomarkers. | Anjani Muthyala Sandeep Sasidharan Kevin John John Amos Lal Ajay K Mishra | 2022 | World Journal of Virology2022，11，5： | 1 |
| 8 | Food poisoning associated methemoglobinemia: Time to wake up显示文摘Dear editor,With interest we read the recent article on methemoglobinemia by Chan et al.[1]Through this letter,we would like to add few additional comments regarding methemoglobinemia and its relevance in medicine practice with regards to food poisoning.While Chan et al[1]successfully managed their patient of methemoglobinemia and could pinpoint choy sum as the responsible agent,we wonder if there were any more cases of choy sum related to methemoglobinemia detected at the same time in the community? | Kamal Kant Sahu Amos Lal Ajay Mishra Susan George | 2020 | World Journal of Emergency Medicine2020，11，2： | 1 |
| 9 | Presentation and outcome of myocardial infarction with nonobstructive coronary arteries in coronavirus disease 2019显示文摘Among the cardiac complications of coronavirus disease 2019(COVID-19),one increasingly reported in the literature is myocardial infarction with nonobstructive coronaries(MINOCA).We reviewed all reported cases of MINOCA in COVID-19 patients to summarize its clinical features,evaluation,and treatment.We performed a literature search in Pubmed using the search terms‘COVID-19’and‘MINOCA’or‘non-obstructive coronaries’.Among the reported cases,the mean age was 61.5 years(SD±13.4),and 50%were men.Chest pain was the presenting symptom in five patients(62.5%),and hypertension was the most common comorbidity(62.5%).ST-elevation was seen in most patients(87.5%),and the overall mortality rate was 37.5%.MINOCA in COVID-19 is an entity with a broad differential diagnosis.Therefore,a uniform algorithm is needed in its evaluation to ensure timely diagnosis and management. | Kevin John Amos Lal Nitish Sharma Amr ElMeligy Ajay K Mishra | 2022 | World Journal of Critical Care Medicine2022，11，3： | 0 |
| 10 | Outcome of repair of chronic tear of the pectoralis major using corkscrew suture anchors by box suture sliding technique显示文摘AIM To assess the functional and clinical results of repair of chronic tears of pectoralis major using corkscrew and sliding suture technique. METHODS In this retrospective study, we reviewed the results of pectoralis major repair in 11 chronic cases(> 6 wk) done between September 2011 and December 2014 at our institute. In all cases repair was done by same surgeon using corkscrew suture anchors and box suture sliding technique. At 6 mo, after surgery magnetic resonance imaging was done to see the integrity of the repair. Functional evaluation was done using Penn and ASES scores. Pre and postoperative Isokinetic strength was measured.RESULTS Average follow-up was 48.27 ± 21.0 mo. The Wilcoxon signed rank test was used to evaluate the outcome scores. The average ASES score increased from an average of 54.63 ± 13.0 preoperatively to 95.09 ± 2.60 after surgery at their last follow-up. The average Penn score also increased from 5.72 ± 0.78, 2.81 ± 1.32 and 45.81 ± 1.72 to 9.36 ± 0.80, 8.27 ± 0.90 and 59 ± 1.34 for pain, satisfaction and function respectively. Follow up magnetic resonance imaging(MRI)(at 6 mo) showed continuity and the bulk of pectoralis major muscle in all cases. Average isokinetic strength deficiency in horizontal adduction at 60° was 13.63% ± 6.93% and at 120° was 10.18% ± 4.93% and in flexion at 60° was 10.72% ± 5.08% and at 120° was 6.63% + 3.74%. Results showed that both ASES and Penn score improved significantly(2 tailed P value = 0.0036).CONCLUSION We could conclude from this series that pectoralis major repair even in chronic cases using 5.5 mm corkscrew anchors give excellent functional and cosmetic results. In chronic cases the repairable length of the tendon is not available and sliding suture technique allows for fixation of worn out tendomuscular junction to bone without letting cutting through the muscle. | Deepak Joshi Jitesh Kumar Jain Deepak Chaudhary Utkarsh Singh Vineet Jain Ajay Lal | 2016 | World Journal of Orthopedics2016，7，10： | 0 |
| 11 | The voyage of stem cell toward terminal differentiation: a brief overview显示文摘一会儿,世界范围的尝试正在被使使用干细胞和茎导出房间产品到大量临床的应用并且为基于房间的治疗的发展。以便利用干细胞并且为治疗学的申请利用他们,理解干细胞的基本生物学并且识别在身体管理这些房间的动力学的因素是很重要的。几个发信号小径作为干细胞的关键管理者出现了。一些这些发信号的小径调整干细胞的 proliferative 能力因此充当干细胞的直接管理者,而其它涉及塑造并且维持干细胞壁龛因此充当干细胞的间接管理者。识别发信号的小径哪个极其影响干细胞的行为并且哪个为维持静止人口是重要的是困难的。一个干细胞与体积人口相比收到不同外来的信号并且不同地对他们作出回应。以便为治疗学的途径操作这些成年房间识别发信号的小径也怎么由影响壁龛由调整 proliferative 地位或间接地直接调整干细胞是关键的。主要挑战是识别不同因素是否提供多样的外来的信号给干细胞和它的女儿房间人口,或是否在干细胞和在他们的行为被反映的女儿房间人口有内在的差别。在这研究,我们将集中于干细胞生物学和区别的各种各样的方面,以及探索潜在的策略干涉区别过程以便获得在再生药适用的房间的需要的收益。 | Shalmoli Bhattacharyya* Ajay Kumar Kishan Lal Khanduja | 2012 | Acta Biochimica et Biophysica Sinica2012，44，6： | 0 |
| 12 | Cocaine-induced methemoglobinemia显示文摘Dear editor,We congratulate Chowdhury et al[1] for their excellentreport and successful management of a young ladysuffering from cocaine-induced methemoglobinemia.Through this letter, we aim to address some additionalconcerns, which would certainly be helpful for acomplete understanding of this topic. | Kamal Kant Sahu Ajay Kumar Mishra Amos Lal Ahmad Daniyal Siddiqui Susan VGeorge | 2021 | World Journal of Emergency Medicine2021，12，1： | 0 |
| 13 | Clinical considerations for critically ill COVID-19 cancer patients:A systematic review显示文摘BACKGROUND The World Health Organization(WHO)on March 11,2020,had declared the novel coronavirus disease 2019(COVID-19)outbreak a global pandemic.The COVID-19 infection continues to be a pandemic and is currently causing overwhelming challenges to healthcare across the nations.Cancer patients represent a unique population vulnerable to COVID-19 infection due to their advanced age,intrinsic frailty,medical comorbidities,immunosuppression,and frequent health care visits for their underlying disease.Robust analysis of COVID-19 infection among cancer patients is crucial to aid in the optimal management of these patients.AIM To identify contributors of worse outcomes in patients with malignancy and COVID-19 and to describe the role of critical care.METHODS In this review,we summarized the information from seminal articles on the presentation and management of patients with COVID-19 and malignancy that were published before December 10,2020.We searched the Pub Med and Medline database for“COVID-19”and“Cancer”,“Malignancy”.Studies published in English,including adults with malignancy and COVID-19 infection,were eligible to be included in this review.Studies on patients that provided details on malignancy,clinical presentation,management,and outcome were included.Various details of malignancy that were included are the site of cancer,histopathological type,stage,chemotherapy,and immunotherapy.Details of COVID-19 infection that were obtained are clinical presentation,the modality of testing,imaging,management,and outcome.Critical care details that were obtained were the type of the organ dysfunction and the requirement of organ support measures,requirement of noninvasive,invasive ventilation,management of vasopressor support,and outcome.Articles that did not have patient details,opinions,letters,and articles not published in English were excluded.All articles were reviewed by 2 independent clinicians.Articles were screened for the above terminologies by independent clinicians.RESULTS We identified two thousand one hundred eighty-six articles,among which fiftyfive were studies that had included patient details pertaining to COVID-19 and cancer(Figure 1).Among these,eighteen studies were eligible and were included in this review as shown in Table 1.A total of 5199 cancer patients were reported.The mean age of patients across all the studies was 64.3 years with male predominance was noted in 12 studies.The clinical presentation and diagnosis of these patients were similar to the general population.Most commonly reported malignancies with COVID-19 infection were hematological in 44%of patients,followed by thoracic malignancy in 11%of patients.The mean number of cancer patients with COVID-19 requiring critical care was 16%.The mean mortality reported was 27.4%.Among the studies that reported the presence of organ dysfunction,respiratory failure was reported in 52%of patients,of which 11.7%required mechanical ventilation.72%of COVID-19 cancer patients required hospitalization across all the studies.The factors which are associated with the worse outcome from COVID-19 infections among the cancer patients were male gender,age≥65 years,presence of higher comorbidity burden based on Charlson comorbidity index and cumulative illness reporting scale>6,and smoking history.CONCLUSION The majority of the cancer patients required intensive care due to respiratory failure and the need for mechanical ventilation.Appropriate contingency planning for these patients in terms of goals of care and judicious resource allocation in the resource-poor regions is the key.The factors associated with worse outcomes from COVID-19 infections were independent of oncological features such as tumor stage,disease status,or current provision of active anticancer therapy and it could be continued with caution. | Chidambaram Ramasamy Ajay Kumar Mishra Kevin John John Amos Lal | 2021 | World Journal of Clinical Cases2021，9，28： | 0 |
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