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| 1 | High preoperative neutrophil-lymphocyte ratio predicts poor survival in patients with gastric cancer显示文摘 | Hideaki Shimada Nobuhiro Takiguchi Osamu Kainuma Hiroaki Soda Atsushi Ikeda Akihiro Cho Akinari Miyazaki Hisashi Gunji Hiroshi Yamamoto Matsuo Nagata | 2010 | Gastric Cancer2010，，3： | 4 |
| 2 | Protective effects of silybin and analogues against X-ray radiation-induced damage显示文摘Silybin (SLB ) 和类似的类似物,也就是 hesperetin (HESP ) , naringenin (NAN ) 和 naringin (NAR ) ,被相信是为某些癌症作为 chemopreventive 代理人被报导了的自然 flavonoids 的活跃成分。而且, SLB 和类似物被决定了快由脉搏 radiolysis 技术从氧化损坏修理 DNA 底。现在的学习被设计评估 SLB 的保护的效果,软 X-ray-induced 上的类似物在 vitro 损坏 DNA 到 plasmid。DNA 损坏被 agarose 胶化电气泳动决定。SLB 和类似物被发现在 micromolar 集中保护 DNA 免受放射损坏的伤害。在测试的混合物之中, HESP 和 SLB 在阻止 DNA 单个海滨的裂缝(SSB ) 的 X-ray-induced 形成是最有效的。有另外的实验的这些结果的比较证明 SLB 和类似物的能力与混合物的能力相关在 vitro 禁止 DNA 损坏清除自由激进分子。我们的工作表明自然 flavonoids, SLB 和类似物可以对放射损坏被用作有势力辐射防护药物。 | Haiying Fu Mingzhang Lin Yosuke Katsumura Akinari Yokoya Kuniki Hata Yusa Muroya Kentaro Fujii Naoya Shikazono | 2010 | Acta Biochimica et Biophysica Sinica2010，42，7： | 4 |
| 3 | Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia显示文摘BACKGROUND Biliary atresia(BA)is a rare pediatric disease.AIM To compare the outcomes of laparoscopic portoenterostomy(Lap-PE)with those of laparotomy(Open-PE)at a single institution.METHODS The surgical outcomes of PE were retrospectively analyzed for patients with a non-correctable type of BA from 2003 to 2020.RESULTS Throughout the assessment period,119 patients received PE for BA treatment,including 66 Open-PE and 53 Lap-PE cases.Although the operation duration was longer(medians:for Open-PE,242 min;for Lap-PE,341 min;P<0.001),blood loss was considerably less(medians:for Open-PE,52 mL;for Lap-PE,24 mL;P<0.001)in the Lap-PE group than in the Open-PE group.The postoperative recovery of the Lap-PE group was more favorable;specifically,both times to resume oral intake and drain removal were significantly shorter in the Lap-PE group.Complete resolution of jaundice was observed in 45 Open-PE cases and 42 Lap-PE cases,with no statistically significant difference(P=0.176).Native liver survival rates were>80%for both groups for the first half year post surgery,followed by a gradual decrease with time;there were no statistically significant differences in the native liver survival rates for any durations assessed.CONCLUSION Lap-PE could be a standard therapy for BA. | Chiyoe Shirota Akinari Hinoki Takahisa Tainaka Wataru Sumida Fumie Kinoshita Kazuki Yokota Satoshi Makita Hizuru Amano Yoichi Nakagawa Hiroo Uchida | 2022 | World Journal of Gastrointestinal Surgery2022，14，1： | 2 |
| 4 | Intracorporeal esophagojejunal anastomosis after laparoscopic total gastrectomy for patients with gastric cancer显示文摘 | Hiroshi Okabe Kazutaka Obama Eiji Tanaka Akinari Nomura Jun-ichiro Kawamura Satoshi Nagayama Atsushi Itami Go Watanabe Seiichiro Kanaya Yoshiharu Sakai | 2009 | Surgical Endoscopy2009，，9： | 2 |
| 5 | Novel zinc alloys for biodegradable surgical staples显示文摘BACKGROUND The development of biodegradable surgical staples is desirable as non-biodegradable Ti alloy staples reside in the human body long after wound healing, which can cause allergic/foreign-body reactions, adhesion, or other adverse effects. In order to develop a biodegradable alloy suitable for the fabrication of surgical staples, we hypothesized that Zn, a known biodegradable metal, could be alloyed with various elements to improve the mechanical properties while retaining biodegradability and biocompatibility. Considering their biocompatibility, Mg, Ca, Mn, and Cu were selected as candidate alloying elements, alongside Ti, the main material of clinically available surgical staples.AIM To investigate the in vitro mechanical properties and degradation behavior and in vivo safety and feasibility of biodegradable Zn alloy staples.METHODS Tensile and bending tests were conducted to evaluate the mechanical properties of binary Zn alloys with 0.1–6 wt.% Mg, Ca, Mn, Cu, or Ti. Based on the results,three promising Zn alloy compositions were devised for staple applications(wt.%): Zn-1.0Cu-0.2Mn-0.1Ti(Zn alloy 1), Zn-1.0Mn-0.1Ti(Zn alloy 2), and Zn-1.0Cu-0.1Ti(Zn alloy 3). Immersion tests were performed at 37℃ for 4 wk using fed-state simulated intestinal fluid(Fe SSIF) and Hank’s balanced salt solution(HBSS). The corrosion rate was estimated from the weight loss of staples during immersion. Nine rabbits were subjected to gastric resection using each Zn alloy staple, and a clinically available Ti staple was used for another group of nine rabbits. Three in each group were sacrificed at 1, 4, and 12 wk post-operation.RESULTS Additions of ≤1 wt.% Mn or Cu and 0.1 wt.% Ti improved the yield strength without excessive deterioration of elongation or bendability. Immersion tests revealed no gas evolution or staple fracture in any of the Zn alloy staples. The corrosion rates of Zn alloy staples 1, 2, and 3 were 0.02 mm/year in HBSS and 0.12, 0.11, and 0.13 mm/year, respectively, in Fe SSIF. These degradation times are sufficient for wound healing. The degradation rate is notably increased under low pH conditions. Scanning electron microscopy and energy dispersive spectrometry surface analyses of the staples after immersion indicated that the component elements eluted as ions in Fe SSIF, whereas corrosion products were produced in HBSS, inhibiting Zn dissolution. In the animal study, none of the Zn alloy staples caused technical failure, and all rabbits survived without complications. Histopathological analysis revealed no severe inflammatory reaction around the Zn alloy staples.CONCLUSION Staples made of Zn-1.0Cu-0.2Mn-0.1Ti, Zn-1.0Mn-0.1Ti, and Zn-1.0Cu-0.1Ti exhibit acceptable in vitro mechanical properties, proper degradation behavior,and in vivo safety and feasibility. They are promising candidates for biodegradable staples. | Hizuru Amano Koichi Miyake Akinari Hinoki Kazuki Yokota Fumie Kinoshita Atsuko Nakazawa Yujiro Tanaka Yasuhiro Seto Hiroo Uchida | 2020 | World Journal of Clinical Cases2020，8，3： | 2 |
| 6 | B‐cell surface marker analysis for improvement of rituximab prophylaxis in ABO‐incompatible adult living donor liver transplantation显示文摘 | Hiroto Egawa Katsuyuki Ohmori Hironori Haga Hiroaki Tsuji Kimiko Yurugi Aya Miyagawa‐Hayashino Fumitaka Oike Akinari Fukuda Jun Yoshizawa Yasutsugu Takada Koichi Tanaka Taira Maekawa Kazue Ozawa Shinji Uemoto | 2007 | Liver Transpl2007，，4： | 1 |
| 7 | Safe and effective treatment of diabetes mellitus associated with chronic liver diseases with an alpha-glucosidase inhibitor, acarbose显示文摘 | Yasuyuki Kihara Yoshimitsu Ogami Akinari Tabaru Hideaki Unoki Makoto Otsuki | 1997 | Journal of Gastroenterology1997，，6： | 1 |
| 8 | Intracorporeal esophagojejunal anastomosis after laparoscopic total gastrectomy for patients with gastric cancer显示文摘 | Hiroshi Okabe Kazutaka Obama Eiji Tanaka Akinari Nomura Jun-ichiro Kawamura Satoshi Nagayama Atsushi Itami Go Watanabe Seiichiro Kanaya Yoshiharu Sakai | 2009 | Surgical Endoscopy2009，，9： | 1 |
| 9 | The Role of Liver Transplantation for Congenital Extrahepatic Portosystemic Shunt显示文摘 | Seisuke Sakamoto Takanobu Shigeta Akinari Fukuda Hideaki Tanaka Atsuko Nakazawa Shunsuke Nosaka Shinji Uemoto Mureo Kasahara | 2012 | Transplantation Journal2012，，12： | 1 |
| 10 | Biliary reconstruction in pediatric live donor liver transplantation: duct-to-duct or Roux-en-Y hepaticojejunostomy显示文摘 | Hideaki Tanaka Akinari Fukuda Takanobu Shigeta Tatsuo Kuroda Takuya Kimura Seisuke Sakamoto Mureo Kasahara | 2010 | Journal of Pediatric Surgery2010，，8： | 1 |
| 11 | High preoperative neutrophil-lymphocyte ratio predicts poor survival in patients with gastric cancer显示文摘 | Hideaki Shimada Nobuhiro Takiguchi Osamu Kainuma Hiroaki Soda Atsushi Ikeda Akihiro Cho Akinari Miyazaki Hisashi Gunji Hiroshi Yamamoto Matsuo Nagata | 2010 | Gastric Cancer2010，，3： | 1 |
| 12 | Portal vein reconstruction in pediatric living donor liver transplantation for patients younger than 1 year with biliary atresia显示文摘 | Hiroyuki Kanazawa Seisuke Sakamoto Akinari Fukuda Takanobu Shigeta Dale L. Loh Toshihiko Kakiuchi Chiaki Karaki Osamu Miyazaki Syunsuke Nosaka Atsuko Nakazawa Mureo Kasahara | 2012 | Journal of Pediatric Surgery2012，，3： | 1 |
| 13 | Pericardiac metastasis from advanced gastric cancer显示文摘 | Atsushi Moriyama Ikuo Murata Tomohiro Kuroda Ichiro Yoshikawa Akinari Tabaru Yoshimitsu Ogami Makoto Otsuki | 1995 | Journal of Gastroenterology1995，，4： | 1 |
| 14 | Efficient algorithms for a mixed - partition problem of graphs without specifying bases 显示文摘 | Akinari Takaki Kimio Kawaguchi | 1998 | Theoretical Computer Science1998，，201： | 1 |
| 15 | Laparoscopic major hepato-biliary-pancreatic surgery: formidable challenge to standardization显示文摘 | Akihiro Cho Hiroshi Yamamoto Matsuo Nagata Nobuhiro Takiguchi Hideaki Shimada Osamu Kainuma Hiroaki Souda Hisashi Gunji Akinari Miyazaki Atsushi Ikeda Tomoko Tohma Ikuko Matsumoto | 2009 | Journal of Hepato - Biliary - Pancreatic Surgery2009，，6： | 1 |
| 16 | Varioliform gastritis and duodenitis associated with protein-losing gastroenteropathy, treated with omeprazole显示文摘 | Ikuo Murata Ichiro Yoshikawa Tomohiro Kuroda Akinari Tabaru Tsutomu Miura Makoto Otsuki | 1996 | Journal of Gastroenterology1996，，1： | 1 |
| 17 | Living donor liver transplantation with hyperreduced left lateral segments显示文摘 | Mureo Kasahara Akinari Fukuda Satoshi Yokoyama Shuichi Sato Hideaki Tanaka Tatsuo Kuroda Toshiro Honna | 2008 | Journal of Pediatric Surgery2008，，8： | 1 |
| 18 | Impact of the current organ allocation system for deceased donor liver transplantation on the outcomes of pediatric recipients: a single center experience in Japan显示文摘 | Seisuke Sakamoto Hajime Uchida Ikumi Hamano Takanobu Shigeta Kengo Sasaki Hiroyuki Kanazawa Akinari Fukuda Mureo Kasahara | 2013 | Pediatric Surgery International2013，，11： | 1 |
| 19 | Efficacy of transanal drainage for anastomotic leakage after laparoscopic low anterior resection of the rectum显示文摘 | Kae Okoshi Yuuki Masano Suguru Hasegawa Koya Hida Kenji Kawada Akinari Nomura Junichiro Kawamura Satoshi Nagayama Tsunehiro Yoshimura Yoshiharu Sakai | 2012 | Asian J Endosc Surg2012，，2： | 1 |
| 20 | Adsorption of trace levels of bromate from aqueous solution by organo-montmorillonite显示文摘 | Ramesh C Yoji M Akinari S | | 0，，51： | 1 |
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