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| 1 | Comparison of inhaled milrinone, nitric oxide and prostacyclin in acute respiratory distress syndrome显示文摘AIM To evaluate the safety and efficacy of inhaled milrinone in acute respiratory distress syndrome(ARDS).METHODS Open-label prospective cross-over pilot study where fifteen adult patients with hypoxemic failure meeting standard ARDS criteria and monitored with a pulmonary artery catheter were recruited in an academic 24-bed medico-surgical intensive care unit. Random sequential administration of i NO(20 ppm) or nebulized epoprostenol(10 μg/mL) was done in all patients. Thereafter, inhaled milrinone(1 mg/mL) alone followed by inhaled milrinone in association with inhaled nitric oxide(iN O) was administered. A jet nebulization device synchronized with the mechanical ventilation was use to administrate the epoprostenol and the milrinone. Hemodynamic measurements and partial pressure of arterial oxygen(PaO_2) were recorded before and after each inhaled therapyadministration.RESULTS The majority of ARDS were of pulmonary cause(n = 13) and pneumonia(n = 7) was the leading underlying initial disease. Other pulmonary causes of ARDS were: Post cardiopulmonary bypass(n = 2), smoke inhalation injury(n = 1), thoracic trauma and pulmonary contusions(n = 2) and aspiration(n = 1). Two patients had an extra pulmonary cause of ARDS: A polytrauma patient and an intra-abdominal abscess Inhaled nitric oxide, epoprostenol, inhaled milrinone and the combination of inhaled milrinone and i NO had no impact on systemic hemodynamics. No significant adverse events related to study medications were observed. The median increase of PaO 2 from baseline was 8.8 mmH g [interquartile range(IQR) = 16.3], 6.0 mm Hg(IQR = 18.4), 6 mm Hg(IQR = 15.8) and 9.2 mm Hg(IQR = 20.2) respectively with i NO, epoprostenol, inhaled milrinone, and i NO added to milrinone. Only i NO and the combination of inhaled milrinone and i NO had a statistically significant effect on PaO 2. CONCLUSION When comparing the effects of inhaled NO, milrinone and epoprostenol, only NO significantly improved oxygenation. Inhaled milrinone appeared safe but failed to improve oxygenation in ARDS. | Martin Albert Daniel Corsilli David R Williamson Marc Brosseau Patrick Bellemare Stéphane Delisle Anne QN Nguyen France Varin | 2017 | World Journal of Critical Care Medicine2017，6，1： | 4 |
| 2 | The diagnosis of mild cognitive impairment due to Alzheimer's disease:Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease显示文摘 | Albert MS DeKosky ST Dickson D | | 0，，03： | 1 |
| 3 | The diagnosis of mildcognitive impairment due to Alzheimer's disease: Recommenda-tions from the National Institute on Aging-Alzheimer * s Association* workgroups on diagnostic guidelines for Alzheimer's disease 显示文摘 | Albert MS DeKosky ST Dickson D | 2011 | Al-zheimers Dement2011，7，3： | 1 |
| 4 | The diagnosis of mild cognitive impairment due to Alzheimer's disease:recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer′s disease显示文摘 | Albert MS DeKosky ST Dickson D | 2011 | Alzheimers Dement2011，7，3： | 1 |
| 5 | The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging and Alzheimer's Association workgroup显示文摘 | Albert MS DeKosky ST Dickson D | 2011 | Alzheimers Dement2011，7，： | 1 |
| 6 | The diagnosis of mild cognitive impairment due to Alzheimer's disease:recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidehnes for Alzheimer' s disease 显示文摘 | Albert MS DeKosky ST Diekson D | 2011 | Alzheimers Dement2011，7，3： | 1 |
| 7 | The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-A1- zheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease显示文摘 | Albert MS DeKosky ST Dickson D | 2011 | Alzheimers Dement2011，7，3： | 1 |
| 8 | Causes of deaths in children under-five years old at a tertiary hospital in Limpopo province of South Africa显示文摘 | Ntuli ST Malangu N Alberts M | | 0，，03： | 1 |
| 9 | The diagnosis of mild cognitive impairment due to Alzheimer’s disease:Recommendations from the National Institute on Aging-Alzheimer,s Association workgroups on diagnostic guidelines for Alzheimer’s disease显示文摘 | Albert MS De Kosky ST Dickson D | 2011 | Alzheimers Dement2011，7，3： | 1 |
| 10 | The diagnosis of mild cognitive impairment due to Alzheimer ' s disease : recommendations from the National Institute on Aging-Alzheimer' s Association workgroups on diagnostic guidelines for Alzheimer' s disease 显示文摘 | Albert MS DeKosky ST Diekson D | 2011 | Alzheimers Dement2011，7，3： | 1 |
| 11 | M2 Kupffer cells promote M1 Kupffer cell apoptosis: A protective mechanism against alcoholic and nonalcoholic fatty liver disease显示文摘 | Jinghong Wan Merieme Benkdane Fatima Teixeira‐Clerc Stéphanie Bonnafous Alexandre Louvet Fouad Lafdil Fran?oise Pecker Albert Tran Philippe Gual Ariane Mallat Sophie Lotersztajn Catherine Pavoine | 2014 | Hepatology2014，，1： | 1 |
| 12 | Effects of sleeve gastrectomy in high fat diet-induced obese mice: respective role of reduced caloric intake, white adipose tissue inflammation and changes in adipose tissue and ectopic fat depots显示文摘 | Anne-Sophie Schneck Antonio Iannelli Stéphanie Patouraux Déborah Rousseau Stéphanie Bonnafous Beatrice Bailly-Maitre Ophélia Thuc Carole Rovere Patricia Panaia-Ferrari Rodolphe Anty Albert Tran Philippe Gual Jean Gugenheim | 2014 | Surgical Endoscopy2014，，2： | 1 |
| 13 | Identification of Adipose Tissue Dendritic Cells Correlated With Obesity-Associated Insulin-Resistance and Inducing Th17 Responses in Mice and Patients显示文摘 | Adeline Bertola Thomas Ciucci Déborah Rousseau Virginie Bourlier Carine Duffaut Stéphanie Bonnafous Claudine Blin-Wakkach Rodolphe Anty Antonio Iannelli Jean Gugenheim Albert Tran Anne Bouloumié Philippe Gual Abdelilah Wakkach | 2012 | Diabetes2012，，9： | 1 |
| 14 | The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease显示文摘 | Albert MS DeKosky ST Dickson D | 2011 | Alzheimers Dement2011，7，： | 1 |
| 15 | The diagnosis of mild cognitive impairment due to Alzheimer's disease: recom- mendations from the national institute on aging-Alzheimer as- sociation workgroups on diagnostic guidelines for Alzheimer's disease 显示文摘 | Albert MS Dekosky ST Dickson D | 2011 | Alzheimer''s Dement2011，7，： | 1 |
| 16 | The diagnosis of mild cog-nitive impairment due to Alzheimer's disease:Recommendations fromthe National Institute on Aging-Alzheimer's Association workgroupson diagnostic guidelines for Alzheimer's disease显示文摘 | Albert MS DeKosky ST Dickson D | 2011 | Alzheimer-s De-ment2011，7，3： | 1 |
| 17 | Association of the IL28B genotype with insulin resistance in patients with chronic hepatitis C显示文摘 | Albert Friedrich St?ttermayer Karoline Rutter Sandra Beinhardt Thomas-Matthias Scherzer Andreas Stadlmayr Harald Hofer Fritz Wrba Petra Steindl-Munda Michael Krebs Christian Datz Michael Trauner Peter Ferenci | 2012 | Journal of Hepatology2012，，3： | 1 |
| 18 | The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging- Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease显示文摘 | Albert MS DeKosky ST Dickson D | 2011 | Alzheimers Dement2011，7，3： | 1 |
| 19 | Hepatic steatosis in Wilson disease – Role of copper and PNPLA3 mutations显示文摘 | Albert Friedrich St?ttermayer Stefan Traussnigg Hans-Peter Dienes Elmar Aigner Rudolf Stauber Karoline Lackner Harald Hofer Judith Stift Friedrich Wrba Andreas Stadlmayr Christian Datz Michael Strasser Andreas Maieron Michael Trauner Peter Ferenci | 2015 | Journal of Hepatology2015，，1： | 1 |
| 20 | The diagnosis of mild cog- nitive impairment due to Alzheimer's disease:recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease显示文摘 | Albert MS DeKosky ST Dickson D | 2011 | Alzheimers Dement2011，7，3： | 1 |
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