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您的检索式：作者名="Alberto Ferri"
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| 1 | Mitochondria and ALS: implications from novel genes and pathways 显示文摘 | Mauro Cozzolino Alberto Ferri Cristiana Valle | 2013 | Molecular and Cellular Neurosciences2013，55，： | 1 |
| 2 | Lipid catabolism and mitochondrial uncoupling are stimulated in brown adipose tissue of amyotrophic lateral sclerosis mouse models显示文摘Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease typically leading to death within 5 years from symptom onset. ALS familial forms are associated with mutations in several genes, including Superoxide Dismutase 1 (SOD1) and Fused in Sarcoma (FUS). Although genes linked to ALS participate in disparate biological processes, ALS genetic variants largely trigger shared pathogenic events such as oxidative stress, protein aggregation and defects in RNA processing. Moreover, ALS patients show systemic hypermetabolism that leads to increased energy expenditure at rest and thus weight loss during the disease course.1 ALS hypermetabolic phenotype and weight loss have been extensively characterized in mice bearing the G93A substitution in SOD1 protein (SOD1-G93A), which exhibit skeletal-muscle metabolic reprogramming before disease onset. | Fabio Ciccarone Serena Castelli Giacomo Lazzarino Silvia Scaricamazza Renata Mangione Sergio Bernardini Savina Apolloni Nadia D'Ambrosi Alberto Ferri Maria Rosa Ciriolo | 2023 | Genes & Diseases2023，10，2： | 0 |
| 3 | Impact of COVID-19 pandemic on the neuropsychiatric status of Wilson’s disease显示文摘We have read with interest the Letter to the Editor by Drs.Zhuang and Zhong,who presented the clinical data of 68 patients with Wilson’s disease(WD)who were admitted to the hospital before and during the coronavirus disease 2019(COVID-19)pandemic,and appreciated their findings on hepatic and some extrahepatic manifestations.Nevertheless,given the strong impact of the pandemic on patients with neurological and psychiatric disorders,we would have expected a worsening of the psychiatric and/or neurological impairments in these patients.In contrast,according to the authors,these manifestations remained,somewhat unexpectedly,unchanged.This finding is in contrast with most of the current literature that highlights not only an increased incidence of mental health disorders in the general population but also an exacerbation of neurological and psychiatric symptoms in patients with chronic diseases,especially in those with pre-existing neuropsychiatric disorders,such as WD.Although the study was mainly focused on the hepatic features of WD patients taking anti-copper treatment,a generic and cumulative definition of neurological and psychiatric manifestations,as in this study,does not allow for further considerations.Future studies during and after the pandemic are necessary to clarify the real impact,either direct or indirect,of the COVID-19 pandemic on the neurological and psychiatric symptoms of WD patients. | Giuseppe Lanza Massimiliano Godani Raffaele Ferri Alberto Raggi | 2021 | World Journal of Gastroenterology2021，27，39： | 0 |
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