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| 1 | Use of genotype-environment interactions to elucidate the pattern of maize root plasticity to nitrogen deficiency显示文摘Maize(Zea mays L.) root morphology exhibits a high degree of phenotypic plasticity to nitrogen(N) de ficiency,but the underlying genetic architecture remains to be investigated Using an advanced BC_4F_3 population,we investigated the root growth plasticity under two contrasted N levels and identi fied the quantitative trait loci(QTLs) with QTL-environment(Q×E)interaction effects. Principal components analysis(PCA) on changes of root traits to N de ficiency(D LN-HN) showed that root length and biomass contributed for 45.8% in the same magnitude and direction on the first PC,while root traits scattered highly on PC_2 and PC_3. Hierarchical cluster analysis on traits for D LN-HN further assigned the BC_4F_3 lines into six groups,in which the special phenotypic responses to N de ficiency was presented These results revealed the complicated root plasticity of maize in response to N de ficiency that can be caused by genotype environment(G×E) interactions. Furthermore,QTL mapping using a multi-environment analysis identi fied 35 QTLs for root traits. Nine of these QTLs exhibited signi ficant Q×E interaction effects. Taken together,our findings contribute to understanding the phenotypic and genotypic pattern of root plasticity to N de ficiency,which will be useful for developing maize tolerance cultivars to N de ficiency. | Pengcheng Li Zhongjuan Zhuang Hongguang Cai Shuai Cheng Ayaz Ali Soomro Zhigang Liu Riliang Gu Guohua Mi Lixing Yuan Fanjun Chen | 2016 | Journal of Integrative Plant Biology2016，58，3： | 8 |
| 2 | An alternative,zeaxanthin epoxidase-independent abscisic acid biosynthetic pathway in plants显示文摘Abscisic acid(ABA)is an important carotenoid-derived phytohormone that plays essential roles in plant response to biotic and abiotic stresses as well as in various physiological and developmental processes.In Arabidopsis,ABA biosynthesis starts with the epoxidation of zeaxanthin by the ABA DEFICIENT 1(ABA1)enzyme,leading to epoxycarotenoids;e.g.,violaxanthin.The oxidative cleavage of 9-cis-epoxycaro-tenoids,a key regulatory step catalyzed by 9-C/S-EPOXYCAROTENOID DIOXYGENASE,forms xanthoxin,which is converted in further rea.ctions mediated by ABA DEFICIENT 2(ABA2),ABA DEFICIENT 3(ABA3),and ABSCISIC ALDEHYDE OXIDASE 3(AAO3)into ABA.By combining genetic and biochemical approaches,we unravel here an ABA1-independent ABA biosynthetic pathway starting upstream of zeaxanthin.We iden-tified the carotenoid cleavage products(i.e.,apocarotenoids,β-apo-11-carotenal,9-cis-β-apo-11-carotenal,3-OH-β-apo-11-carotenal,and 9-cis-3-OH-β-apo-11-carotenal)as intermediates of this ABA1-independent ABA biosynthetic pathway.Using labeled compounds,we showed thatβ-apo-11-carotenal,9-cis-β-apo-11-carotenal,and 3-OH-β-apo-11-carotenal are successively converted into 9-cis-3-OH-β-apo-11-carotenal,xanthoxin,and finally into ABA in both Arabidopsis and rice.When applied to Arabidopsis,theseβ-apo-11-carotenoids exert ABA biological functions,such as maintaining seed dormancy and inducing the expression of ABA-responsive genes.Moreover,the transcdptomic analysis revealed a high overlap of differentially expressed genes regulated byβ-apo-11-carotenoids and ABA,suggesting thatβ-apo-11-carot-enoids exert ABA-independent regulatory activities.Taken together,our study identifies a biological function for the common plant metabolites,β-apo-11-carotenoids,extends our knowledge about ABA biosynthesis,and provides new insights into plant apocarotenoid metabolic networks. | Kun-Peng Jia Jianing Mi Shawkat Ali Hajime Ohyanagi Juan C.Moreno Abdugaffor Ablazov Aparna Balakrishna Lamis Berqdar Alessia Fiore Gianfranco Diretto Claudio Martínez Angel R.de Lera Takashi Gojobori Salim Al-Babili | 2022 | Molecular Plant2022，15，1： | 2 |
| 3 | LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells显示文摘We recently demonstrated that leukocyte Ig-like receptor 4(LILRB4)expressed by monocytic acute myeloid leukemia(AML)cells mediates T-cell inhibition and leukemia cell infiltration via its intracellular domain.The cytoplasmic domain of LILRB4 contains three immunoreceptor tyrosine-based inhibitory motifs(ITIMs);the tyrosines at positions 360,412,and 442 are phosphorylation sites.Here,we analyzed how the ITIMs of LILRB4 in AML cells mediate its function.Our in vitro and in vivo data show that Y412 and Y442,but not Y360,of LILRB4 are required for T-cell inhibition,and all three ITIMs are needed for leukemia cell infiltration.We constructed chimeric proteins containing the extracellular domain of LILRB4 and the intracellular domain of LILRB1 and vice versa.The intracellular domain of LILRB4,but not that of LILRB1,mediates T-cell suppression and AML cell migration.Our studies thus defined the unique signaling roles of LILRB4 ITIMs in AML cells. | Zunling Li Mi Deng Fangfang Huang Changzhu Jin Shuang Sun Heyu Chen Xiaoye Liu Licai He Ali HSadek Cheng Cheng Zhang | 2020 | Cellular & Molecular Immunology2020，17，3： | 1 |
| 4 | Evolution of electroencephalogram signal analysis techniques during anesthesia显示文摘 | Al-Kadi MI Reaz MB Ali MA | 2013 | Sensors(Basel)2013，13，5： | 1 |
| 5 | Real-time signal processing for fetal heart rate monitoring显示文摘 | Ibrahimy MI Ahmed F Ali MAM | 2003 | IEEE Trans Biomedical Engineering2003，50，2： | 1 |
| 6 | Hamas and the Two -State Solution: Villain, Victim or Missing Ingredient? 显示文摘 | Sherifa Zuhur Ali Abunimah Haim Malka Shibley Telha- mi | 2008 | Middle East Policy2008，15，2： | 1 |
| 7 | Fenton's peroxidation and coagulation processes for the treatment of combined industrial and domestic wastewater显示文摘 | BADAWY MI ALI MEM | 2006 | Joumal of hazardous materials2006，136，： | 1 |
| 8 | Cdc42: Role in cancer manage- ment显示文摘 | Qadir MI Parveen A Ali M | 2015 | Chem Biol Drug Des2015，86，4： | 1 |
| 9 | bis-Sigmodiol: a new prenylflavanone dimer from Erythrina sigmoidea Hua (Fabaceae) of Nigeria 显示文摘 | All MS Ali MI Onocha PA | 2011 | J Asian Nat Prod Res2011，13，2： | 1 |
| 10 | Cortisol and uncomplicated Plasmodium falciparum malaria in an area of unstable malaria transmission in eastern Sudan显示文摘Objective:To investigate the levels of serum Cortisol in patients with uncomplicated Plasmodium falciparum(P.falciparum) malaria in an area of unstable malaria transmission in eastern Sudan. Methods:The concentrations of Cortisol were measured in sera of 25 patients with uncomplicated P.fylciparum malaria(at presentation,24 h and 7 d later) and 25 healthy volunteers using radioimmunoassay gamma counter.Results:There was no significant difference in mean(SD) of total Cortisol levels in patients with malaria in comparison with the control group;602.2(369.6) vs. 449.2(311.7) ng/mL,P=0.12.In patients with uncomplicated P.falciparum malaria,the mean(SD) presenting Cortisol levels were significantly higher in comparison to the levels on day 7;602.2 (369.6) vs.373.6(139.1) ng/mL,P=0.009.In the patients with uncomplicated P.falciparum malaria (on presentation) Cortisol levels were not correlated with initial temperature or the presenting parasitaemia.Conclusions:Thus,Cortisol levels were not significantly different between the patients and the controls. | Ibrahim EA Kheir MM Elhardello OA Almahi WA Ali NI Elbashir MI Ishag Adam | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，2： | 1 |
| 11 | The sheep as an animal model for heart valve research显示文摘 | Ali MI Kumar SP Bjornstad K | 1996 | Cadiovasc Surg1996，4，4： | 1 |
| 12 | Mechanical ventilation in patients with G,,illaln- Barre syndrome显示文摘 | Ali MI Fernandez - Perez ER Pendem S Brown DR Wi- jdicks EF Gajic O | 2006 | Respir Care2006，51，12： | 1 |
| 13 | 显示文摘 | Ali L Khan AK Mamun MI etal | 1993 | Planta Medicine1993，，59： | 1 |
| 14 | Microbial transformation of antifertility agents, norethisterone and 17α-ethynylestradiol显示文摘 | Choudhary MI Musharraf SG Ali RA | 2004 | Zeitschrift fur Naturforschung2004，59，： | 1 |
| 15 | Studies on hypoglycemic effects of fruit pulp,seed,whole plant of momordica charantia on normal and diabetic model rats显示文摘 | Ali L Khan AK Mamun MI | 1993 | Plabta Med1993，59，： | 1 |
| 16 | Inhibition of ct-glucosi- dase by oleanolic acid and its synthetic derivatives显示文摘 | Ali MS Jahangir M Choudhary MI | 2002 | Phy- tochemistry2002，60，2： | 1 |
| 17 | Anomaly Based Camera Prioritization in Large Scale Surveillance Networks显示文摘Digital surveillance systems are ubiquitous and continuously generate massive amounts of data,and manual monitoring is required in order to recognise human activities in public areas.Intelligent surveillance systems that can automatically identify normal and abnormal activities are highly desirable,as these would allow for efficient monitoring by selecting only those camera feeds in which abnormal activities are occurring.This paper proposes an energy-efficient camera prioritisation framework that intelligently adjusts the priority of cameras in a vast surveillance network using feedback from the activity recognition system.The proposed system addresses the limitations of existing manual monitoring surveillance systems using a three-step framework.In the first step,the salient frames are selected from the online video stream using a frame differencing method.A lightweight 3D convolutional neural network(3DCNN)architecture is applied to extract spatio-temporal features from the salient frames in the second step.Finally,the probabilities predicted by the 3DCNN network and the metadata of the cameras are processed using a linear threshold gate sigmoid mechanism to control the priority of the camera.The proposed system performs well compared to state-of-theart violent activity recognition methods in terms of efficient camera prioritisation in large-scale surveillance networks.Comprehensive experiments and an evaluation of activity recognition and camera prioritisation showed that our approach achieved an accuracy of 98%with an F1-score of 0.97 on the Hockey Fight dataset,and an accuracy of 99%with an F1-score of 0.98 on the Violent Crowd dataset. | Altaf Hussain Khan Muhammad Hayat Ullah Amin Ullah Ali Shariq Imran Mi Young Lee Seungmin Rho Muhammad Sajjad | 2022 | Computers, Materials & Continua2022，，2： | 1 |
| 18 | Cardiac troponin I lev- els and alveolararterial oxygen gradient in patients with community-ac- quired pneumonia显示文摘 | Moammar MQ Ali MI Mahmood MA | 2010 | Heaet Lung Circ2010，19，2： | 1 |
| 19 | Studies on hypoglycemic effects of fruit pulp,seed,and whole plant of Momordica charantia on normal and diabetic model rats显示文摘 | Ali L Kham AK Mamun MI | 1993 | Planta Medica1993，59，5： | 1 |
| 20 | Cardiac troponin I levels and alveolar - arterial oxygen gradient in patients with community - acquired pneumonia显示文摘 | Moammar MQ Ali MI Mahmood NA | 2010 | Heart Lung Circ2010，19，2： | 1 |
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