|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 2 | Stereotactic body radiation therapy for management of spinal metastases in patients without spinal cord compression: a phase 1–2 trial显示文摘 | Xin Shelley Wang Laurence D Rhines Almon S Shiu James N Yang Ugur Selek Ibrahima Gning Ping Liu Pamela K Allen Syed S Azeem Paul D Brown Hadley J Sharp David C Weksberg Charles S Cleeland Eric L Chang | 2012 | Lancet Oncology2012，，4： | 2 |
| 3 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 4 | Red imported fire ant impacts on northern bobwhite populations显示文摘 | Allen C R Lutz R S Demarais S | 1995 | Ecol Appl1995，，3： | 1 |
| 5 | Adaptation of HIV-1to human leukocyte antigen class I显示文摘 | Kawashima Y Pfafferott K Frater J Matthews P Payne R Addo M Gatanaga H Fujiwara M Hachiya A Koizumi H Kuse N Oka S Duda A Prendergast A Crawford H Leslie A Brumme Z Brumme C Allen T Brander C Kaslow R Tang J Hunter E Allen S Mulenga J Branch S Roach T John M Mallal S Ogwu A Shapiro R Prado J G Fidler S Weber J Pybus O G Klenerman P Ndung'u T Phillips R Heckerman D Harrigan P R Walker B D Takiguchi M Goulder P | 2009 | Nature2009，458，7238： | 1 |
| 6 | Zonal distribution of glomerular collapse in renal allografts: possible role of vascular changes显示文摘 | Nadasdy T Allen C Zand M S | 2002 | Hum Pathol2002，33，： | 1 |
| 7 | Degradation of carboxylated styrene butadiene rubber based water born paints:Part 2 e Models to predict UV stability and water absorption through central composite design 显示文摘 | Jubete E Liauw C M Allen N S | 2007 | Polym Degrad Stab2007，92，： | 1 |
| 8 | Tetraploid eastem oysters:An arduous effort显示文摘 | Supan J E Allen S K Wilson C A | 2000 | J Shellfish Res2000，19，1： | 1 |
| 9 | Nonste- ruidal anti in flammatory drugs for pain in women with endometriosis 显示文摘 | Allen C Hopewell S Prentice A | 2009 | Co - chrane Database SystRev2009，2，： | 1 |
| 10 | TEMORA 1 :A New Zircon Standard for Phanerozoic U-Pb Geochronology 显示文摘 | Black L P Kamo S L Allen C M | 2003 | Chemical Geology2003，200，12： | 1 |
| 11 | The influence of epitope availability on atomic-force microscope studies of antigen-antibody interactions显示文摘 | ALLEN S DAVIES J DAVIES M C | 1999 | Biochem1999，341，1： | 1 |
| 12 | p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson′s diseases显示文摘 | BRETAUD S ALLEN C INGHAM P W | 2007 | J Neurochem2007，100，6： | 1 |
| 13 | High-level transgene expression in plant cell: effects of a strong scaffold attachment region from tobacco显示文摘 | Allen G C Spiker S | 1996 | Plant Cell1996，8，： | 1 |
| 14 | Use of an immunoassay as a means to detect polychlorinated biphenyls in animal fat显示文摘 | Jaborek H S Host C V Allen R | 2001 | Food Additives and Contaminants2001，18，2： | 1 |
| 15 | VM determining the role of W in suppressing crystallization ofelectroless Ni-W-P films 显示文摘 | ANTONELLI S B ALLEN T L JOHNSON D C | 2006 | J Electrochem Soc2006，153，： | 1 |
| 16 | Rise in carbon dioxide changes soil structure显示文摘 | RILLIG M C WRIGHT S F ALLEN M F | 1999 | Nature1999，400，： | 1 |
| 17 | Potentially active faults in dam foundations显示文摘 | SHERARD J L CLUFF L S ALLEN C R | 1974 | Géotechnique1974，，03： | 1 |
| 18 | Olive oil volatilecompounds,flavour development and quality : A critical review显示文摘 | Kalua C M Allen M S Bedgood D R | 2007 | Food Chem2007，100，： | 1 |
| 19 | Model for discontinuous actuation of ferromagnetic shape memory alloy under stress显示文摘 | Murray S J O'Handley R C Allen S M | 2001 | J Appl Phy2001，89，2： | 1 |
| 20 | Therapeutic peptidomimetic strategies for autoimmune diseases:costimulation blockade显示文摘 | Allen S D Rawale S V Whitacre C C | 2005 | J Pept Res2005，65，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员