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| 1 | Acute-on-chronic liver failure:recent update显示文摘Acute on chronic liver failure(ACLF) was first described in 1995 as a clinical syndrome distinct to classic acute decompensation.Characterized by complications of decompensation,ACLF occurs on a background of chronic liver dysfunction and is associated with high rates of organ failure and significant short-term mortality estimated between45%and 90%.Despite the clinical relevance of the condition,it still remains largely undefined with continued disagreement regarding its precise etiological factors,clinical course,prognostic criteria and management pathways.It is concerning that,despite our relative lack of understanding of the condition,the burden of ACLF among cirrhotic patients remains significant with an estimated prevalence of 30.9%.This paper highlights our current understanding of ACLF,including its etiology,diagnostic and prognostic criteria and pathophysiology.It is evident that further refinement of the ACLF classification system is required in order to detect high-risk patients and improve short-term mortality rates.The field of metabolomics certainly warrants investigation to enhance diagnostic and prognostic parameters,while the use of granulocyte-colony stimulating factor is a promising future therapeutic intervention for patients with ACLF. | Azeem Alam Ka Chun Suen Daqing Ma | 2017 | The Journal of Biomedical Research2017，31，4： | 16 |
| 2 | Current technology development for CO2 utilization into solar fuels and chemicals:A review显示文摘The continuous consumption of fossil fuels causes two important impediments including emission of large concentrations of CO2 resulting in global warming and alarming utilization of energy assets.The conversion of greenhouse gas CO2 into solar fuels can be an expedient accomplishment for the solution of both problems,all together.CO2 reutilization into valuable fuels and chemicals is a great challenge of the current century.Owing to limitations in traditional approaches,there have been developed many novel technologies such as photochemical,biochemical,electrochemical,plasma-chemical and solar thermochemical.They are currently being used for CO2 capture,sequestration,and utilization to transform CO2 into valuable products such as syngas,methane,methanol,formic acid,as well as fossil fuel consumption reduction.This review summarizes different traditional and novel thermal technologies used in CO2 conversion with detailed information about their working principle,types,currently adopted methods,developments,conversion rates,products formed,catalysts and operating conditions.Moreover,a comparison of these novel technologies in terms of distinctive key features such as conversion rate,yield,use of earth metals,renewable energy,investment,and operating cost has been provided in order to have a useful review for future research direction. | Azeem Mustafa Bachirou Guene Lougou Yong Shuai Zhijiang Wang Heping Tan | 2020 | Journal of Energy Chemistry2020，29，10： | 16 |
| 3 | 解脲支原体、沙眼衣原体与精液白细胞及精子形态的关系显示文摘目的探讨解脲支原体、沙眼衣原体、精液白细胞与精子形态的关系。方法对1023例男性不育患者精液样本进行检测,解脲支原体采用培养法,沙眼衣原体采用生化酶法进行检测,白细胞采用联苯胺染色方法进行检测,精子形态检测采用计算机辅助系统下人工修正的方法进行分析。结果 UU阳性率为27.57%,CT 阳性率为30.11%。UU阳性组、CT阳性组及UU+CT阳性组正常形态精子百分率均显著低于对照组(P<0.01),亦均显著低于阴性组(P<0.05,P<0.01)。UU阳性组、CT阳性组及UU+CT阳性组白细胞异常率均显著高于对照组(P<0.001),亦均显著高于阴性组(P<0.001)。白细胞异常组正常形态精子百分率显著低于对照组和白细胞正常组(P<0.001)。结论UU、CT感染、白细胞、精子形态关系密切,UU、CT感染可能直接影响精子形态,亦可能通过激发白细胞异常,通过白细胞机制影响精子形态。 | 陈鑫 许宗革 郑贤红 白立晶 Shaik Abdul Azeem 刘睿智 | 2008 | 中国男科学杂志2008，22，10： | 15 |
| 4 | 沼液与化肥配施对耕层土壤化学性状及玉米产量品质的影响显示文摘以玉米品种登海605为试材,研究沼液与化肥配施对耕层土壤化学性状及玉米产量、品质的影响。基于等氮原则,共设6个处理,即处理1:CK(空白);处理2:CF(常规施肥,基肥为有机肥与化肥配施,追肥为化肥);处理3:40%ZF+60%HF(40%沼液+60%化肥);处理4:60%ZF+40%HF(60%沼液+40%化肥);处理5:80%ZF+20%HF(80%沼液+20%化肥);处理6:100%ZF(全沼液)。结果表明,施用沼液能提高土壤有机质含量,且提高幅度与沼液用量呈正相关关系。苗期CF处理土壤速效养分含量明显高于沼液处理,但至成熟期60%ZF+40%HF处理土壤速效养分含量最高。与CF相比,施用沼液提高土壤盐分含量和pH值,玉米成熟期40%ZF+60%HF、60%ZF+40%HF、80%ZF+20%HF、100%ZF处理的土壤盐分含量和pH值分别增加22.48%、47.50%、59.78%、71.25%和1.19%、2.25%、3.00%、3.84%。成熟期玉米秸秆养分含量、籽粒产量与品质均以60%ZF+40%HF处理最高,方差分析表明,该处理与80%ZF+20%HF处理产量无显著差异。综合分析认为,60%沼液与40%化肥配施适合玉米生长对养分的需求,产量最高,品质最优。 | 崔宇星 Muhammad Azeem 孙吉翠 张忠兰 杨守军 | 2020 | 山东农业科学2020，52，5： | 15 |
| 5 | Therapeutic options for the management of pancreatic cancer显示文摘Since its initial characterization, pancreatic ductal adenocarcinoma has remained one of the most devastating and difficult cancers to treat. Pancreatic cancer is the fourth leading cause of death in the United States, resulting in an estimated 38460 deaths annually. With few screening tools available to detect this disease at an early stage, 94% of patients will die within five years of diagnosis. Despite decades of research that have led to a better understanding of the molecular and cellular signaling pathways in pancreatic cancer cells, few effective therapies have been developed to target these pathways. Other treatment options have included more sophisticated pancreatic cancer surgeries and combination therapies. While outcomes have improved modestly for these patients, more effective treatmentsare desperately needed. One of the greatest challenges in the future of treating this malignancy will be to develop therapies that target the tumor microenvironment and surrounding pancreatic cancer stem cells in addition to pancreatic cancer cells. Recent advances in targeting pancreatic stellate cells and the stroma have encouraged researchers to shift their focus to the role of desmoplasia in pancreatic cancer pathobiology in the hopes of developing newer-generation therapies. By combining novel agents with current cytotoxic chemotherapies and radiation therapy and personalizing them to each patient based on specific biomarkers, the goal of prolonging a patient's life could be achieved. Here we review the most effective therapies that have been used for the treatment of pancreatic cancer and discuss the future potential of therapeutic options. | Maria L Rossi Azeem A Rehman Christopher S Gondi | 2014 | World Journal of Gastroenterology2014，20，32： | 13 |
| 6 | Computed tomography overestimation of esophageal tumor length: Implications for radiotherapy planning显示文摘AIM:To assess the relationship between preoperative computed tomography(CT)and postoperative pathological measurements of esophageal tumor length and the prognostic significance of CT tumor length data.METHODS:A retrospective study was carried out in 56 patients who underwent curative esophagogastrectomy.Tumor lengths were measured on the immediate preoperative CT and on the post-operative resection specimens.Inter-and intra-observer variations in CT measurements were assessed.Survival data were collected.RESULTS:There was a weak correlation between CT and pathological tumor length(r=0.30,P=0.025).CT lengths were longer than pathological lengths in 68%(38/56)of patients with a mean difference of 1.67 cm(95%CI:1.18-2.97).The mean difference in measurements by two radiologists was 0.39 cm(95% CI:-0.59-1.44).The mean difference between repeat CT measured tumor length(intra-observer variation) were 0.04 cm(95%CI:-0.59-0.66)and 0.47 cm (95%CI:-0.53-1.47).When stratified,patients not receiving neoadjuvant chemotherapy showed a strong correlation between CT and pathological tumor length(r =0.69,P=0.0014,n=37)than patients that did(r= 0.13,P=0.43,n=19).Median survival with CT tumor length>5.6 cm was poorer than with smaller tumors,but the difference was not statistically significant.CONCLUSION:Esophageal tumor length assessed using CT does not reflect pathological tumor extent and should not be the only modality used for management decisions,particularly for planning radiotherapy. | Karim Sillah Luke R Williams Hans-Ulrich Laasch Azeem Saleem Gillian Watkins Susan A Pritchard Patricia M Price Catharine M West Ian M Welch | 2010 | World Journal of Gastrointestinal Oncology2010，2，4： | 10 |
| 7 | Early repolarization syndrome: A cause of sudden cardiac death显示文摘Early repolarization syndrome(ERS), demonstrated as J-point elevation on an electrocardiograph, was formerly thought to be a benign entity, but the recent studies have demonstrated that it can be linked to a considerable risk of life- threatening arrhythmias and sudden cardiac death(SCD). Early repolarization characteristics associated with SCD include high-amplitude J-point elevation, horizontal and/or downslopping ST segments, and inferior and/or lateral leads location. The prevalence of ERS varies between 3% and 24%, depending on age, sex and J-point elevation(0.05 m V vs 0.1 m V) being the main determinants.ERS patients are sporadic and they are at a higher risk of having recurrent cardiac events. Implantable cardioverter-defibrillator implantation and isoproterenol are the suggested therapies in this set of patients. On the other hand, asymptomatic patients with ERS are common and have a better prognosis. The risk stratification in asymptomatic patients with ERS still remains a grey area. This review provides an outline of the up-to-date evidence associated with ERS and the risk of life- threatening arrhythmias. Further prospective studies are required to elucidate the mechanisms of ventricular arrhythmogenesis in patients with ERS. | Abdi Ali Nida Butt Azeem S Sheikh | 2015 | World Journal of Cardiology2015，7，8： | 9 |
| 8 | Postoperative sleep disorders and their potential impacts on surgical outcomes显示文摘Postoperative sleep disturbance is a common occurrence with significant adverse effects on patients including delayed recovery,impairment of cognitive function,pain sensitivity and cardiovascular events.The development of postoperative sleep disturbance is multifactorial and involves the surgical inflammatory response,the severity of surgical trauma,pain,anxiety,the use of anesthetics and environmental factors such as nocturnal noise and light levels.Many of these factors can be managed perioperatively to minimize the deleterious impact on sleep.Pharmacological and non-pharmacological treatment strategies for postoperative sleep disturbance include dexmedetomidine,zolpidem,melatonin,enhanced recovery after surgery(ERAS) protocol and controlling of environmental noise and light levels.It is likely that a combination of pharmacological and non-pharmacological therapies will have the greatest impact;however,further research is required before their use can be routinely recommended. | Sanketh Rampes Katie Ma Yasmin Amy Divecha Azeem Alam Daqing Ma | 2020 | The Journal of Biomedical Research2020，34，4： | 9 |
| 9 | 热处理改善齿科用钛合金的体外腐蚀、磨损和力学性能显示文摘研究热处理对新型Ti20Nb13Zr (TNZ)合金组织、力学性能、耐磨性和人工唾液(AS)体外腐蚀防护性能的影响。采用X射线衍射(XRD)、扫描电镜(SEM)等进行结构和显微组织分析。采用电化学阻抗谱和线性极化电阻技术研究样品在AS中浸泡168 h后的体外耐腐蚀性能。采用线性往复摩擦计对其摩擦特性进行研究。SEM分析结果表明,固溶处理和时效影响α相的尺寸和分布。空冷和时效处理后样品具有最高的显微硬度和宏观硬度,其耐磨性分别比未处理样品高25%和30%。冷却速率对TNZ合金的耐腐蚀性有显著影响。经过处理的样品在AS中浸泡168 h后,腐蚀速率降低50%。经炉冷和时效处理的样品在AS中浸泡168 h后具有最好的耐腐蚀性。在经过处理的样品中,时效样品表现出更优异的力学性能、耐磨性能和体外耐腐蚀性能。 | Mohamed HUSSEIN Akeem YADESINA Madhan KUMAR Mohamed AZEEM Ahmad SOROUR Nasser AL-AQEELI | 2021 | Transactions of Nonferrous Metals Society of China2021，31，4： | 9 |
| 10 | 沼液过量还田对土壤环境容量及玉米生长的影响显示文摘以沼液过量还田为前提,探讨沼液不同还田量对土壤环境质量和玉米生长发育的影响,提出沼液还田的安全容量。根据目标需氮量确定沼液施用量,共设5个处理:未施加任何肥料(N0 t/hm^(2),CK);1倍氮当量沼液(N 0.885 t/hm^(2),1N);2倍氮当量沼液(N 1.770 t/hm^(2),2N);3倍氮当量沼液(N 2.655 t/hm^(2),3N);4倍氮当量沼液(N 3.540 t/hm^(2),4N)。结果表明,沼液还田可显著增加玉米田土壤中Cu、Zn含量,1N处理为最佳安全容量,2N、3N、4N处理土壤存在Cu、Zn污染风险,其中,玉米完熟时4N处理Cu、Zn含量分别超出风险筛选值10.96%和10.36%,风险最大。与对照相比,沼液还田显著增加玉米苗期土壤中可溶性盐含量,提高土壤的pH值,但随着生育期的延长,可溶性盐含量和pH值呈下降趋势;至玉米的完熟期,1N、2N、3N、4N处理土壤可溶性盐含量比对照分别高出30.59%、52.16%、72.35%、108.63%,土壤pH值比对照分别高出3.95%、6.41%、9.05%、13.65%。所有处理的蛔虫卵死亡率均为100%,故沼液还田不存在蛔虫卵存活的安全风险,但3N与4N处理土壤存在大肠杆菌污染的风险,完熟期这2个处理土壤的大肠杆菌菌群含量分别为20、30个/g。沼液还田可增加玉米产量和改善玉米品质,以3N处理产量最高和品质最优,与对照相比,粗蛋白、粗脂肪、粗淀粉含量分别提高了19.82%、89.01%、11.31%,产量是对照的2.08倍。综合分析认为,以玉米产量最大和品质最优为优先目标时,3N处理为最优,以土壤环境安全容量为优先目标时,1N处理为最优。 | 李金澄 孙吉翠 杨丽 MUHAMMAD Azeem 张忠兰 杨守军 | 2021 | 河南农业科学2021，50，5： | 8 |
| 11 | Nonlinear joint PP-PS AVO inversion based on improved Bayesian inference and LSSVM显示文摘Multiwave seismic technology promotes the application of joint PP–PS amplitude versus offset (AVO) inversion;however conventional joint PP–PS AVO inversioan is linear based on approximations of the Zoeppritz equations for multiple iterations. Therefore the inversion results of P-wave, S-wave velocity and density exhibit low precision in the faroffset;thus, the joint PP–PS AVO inversion is nonlinear. Herein, we propose a nonlinear joint inversion method based on exact Zoeppritz equations that combines improved Bayesian inference and a least squares support vector machine (LSSVM) to solve the nonlinear inversion problem. The initial parameters of Bayesian inference are optimized via particle swarm optimization (PSO). In improved Bayesian inference, the optimal parameter of the LSSVM is obtained by maximizing the posterior probability of the hyperparameters, thus improving the learning and generalization abilities of LSSVM. Then, an optimal nonlinear LSSVM model that defi nes the relationship between seismic refl ection amplitude and elastic parameters is established to improve the precision of the joint PP–PS AVO inversion. Further, the nonlinear problem of joint inversion can be solved through a single training of the nonlinear inversion model. The results of the synthetic data suggest that the precision of the estimated parameters is higher than that obtained via Bayesian linear inversion with PP-wave data and via approximations of the Zoeppritz equations. In addition, results using synthetic data with added noise show that the proposed method has superior anti-noising properties. Real-world application shows the feasibility and superiority of the proposed method, as compared with Bayesian linear inversion. | Xie Wei Wang Yan-Chun Liu Xue-Qing Bi Chen-Chen Zhang Feng-Qi Fang Yuan Tahir Azeem | 2019 | Applied Geophysics2019，16，1： | 7 |
| 12 | 总固体浓度对猪粪水快速厌氧发酵的影响显示文摘为了探讨中温(30℃)条件下不同总固体(TS)浓度对猪粪水快速厌氧发酵的影响,以期获得猪粪水快速厌氧处理的最佳TS浓度和发酵时间,试验采用厌氧发酵方法共设3个TS浓度(4%,处理1;5%,处理2;6%,处理3)处理,发酵8 d,测定沼液TS浓度、pH值、产气量和全氮、全磷、全钾、甲烷含量。结果表明:在发酵的前4 d,处理1,2,3的产气量分别达到总产气量的87.5%、87.9%和83.3%,处理3的甲烷含量最高,但与处理2无显著差异(P>0.05);在发酵的前4 d,各处理沼液pH值下降幅度随粪水TS含量的增大而增大。在整个厌氧发酵期间,各处理粪水TS浓度的变化与有机质变化趋势相似,发酵对各处理沼液中的全氮、全磷、全钾含量无显著影响(P>0.05)。说明物料的TS浓度为5%时,发酵4 d适合猪粪水的快速厌氧发酵处理。 | 孙嘉洵 台子晗 Muhammad Azeem 孙吉翠 张忠兰 杨守军 | 2019 | 黑龙江畜牧兽医2019，0，20： | 6 |
| 13 | 沼液与化肥配施对苹果生长及土壤理化性状的影响——以烟台红富士苹果为例显示文摘以10年生苹果树品种烟台红富士为试验试材,探讨苹果的生长情况、土壤理化性质同沼液化肥搭配施用比例的关系,期望为沼液作肥料进行利用提供科学依据。各组所施肥料含氮量相等,设置7种处理:处理1,CK(空白);处理2,CF(基肥为牛粪有机肥,追肥为化肥);处理3,40%ZF+60%HF(40%沼液+60%化肥);处理4,60%ZF+40%HF(60%沼液+40%化肥);处理5,80%ZF+20%HF(80%沼液+20%化肥);处理6,100%ZF(全沼液);处理7,100%HF(全化肥)。结果表明,施用沼液能使土壤有机质含量、盐分含量和pH值提高。与100%HF处理比较,搭配施用的沼液与化肥在果树花期能够使土壤速效养分含量降低,至果实成熟期又升高,其中以40%ZF+60%HF处理最高。沼液与化肥配施不仅能提高苹果产量,而且能增加果实中糖度、维生素C含量和硬度,降低果实的酸度。综合果实品质和产量而言,40%ZF+60%HF处理最好,但与60%ZF+40%HF处理无显著差异。80%ZF+20%HF处理与100%ZF处理果实中检出Cu和Zn的残留,抗生素均未检出。综合统计分析认为,40%ZF+60%HF配施较适合苹果的生长。 | 高炜城 Muhammad Azeem 孙吉翠 张忠兰 李金澄 杨守军 | 2020 | 江苏农业科学2020，48，21： | 5 |
| 14 | 沼液与化肥不同比例配施对番茄产量和品质的影响显示文摘采用随机区组设计,共6个处理,分别为CK(空白对照)、CF(有机肥基施和化肥追施)、ZF 40%+HF 60%(40%沼液+60%化肥)、ZF 60%+HF 40%(60%沼液+40%化肥)、ZF 80%+HF 20%(80%沼液+20%化肥)、ZF 100%(纯沼液),研究了沼液与化肥不同比例配施对番茄产量和品质的影响。结果表明,沼液与化肥配施提高了番茄叶片叶绿素含量,其中以ZF 60%+HF 40%处理最高,且在番茄定植后的30、65和110 d分别比CF和ZF 100%处理提高了3.74%和7.52%、3.36%和21.38%、30.76%和37.22%。沼液与化肥配施提高了番茄果实中维生素C和可溶性糖含量,降低了可滴定酸含量,沼液施用量越多,对果实品质改善效果越明显。番茄产量以ZF 60%+HF 40%处理最高,分别是CK、CF、ZF 40%+HF 60%、ZF 80%+HF 20%、ZF处理的1.58倍、1.15倍、1.08倍、1.12倍和1.21倍。ZF80%+HF 20%和ZF100%处理果实中检测到铜、锌等重金属,所有处理均未检出抗生素。综合分析认为,ZF 60%+HF 40%处理能明显提高番茄产量和改善果实品质。 | 任寒硕 Muhammad Azeem 孙吉翠 张忠兰 杨守军 | 2020 | 中国瓜菜2020，33，9： | 4 |
| 15 | Viral respiratory infections among Hajj pilgrims in 2013显示文摘Middle East respiratory syndrome coronavirus(MERS-Co V) has emerged in the Arabian Gulf region, with its epicentre in Saudi Arabia, the host of the ‘Hajj' which is the world's the largest mass gathering. Transmission of MERS-Co V at such an event could lead to its rapid worldwide dissemination. Therefore, we studied the frequency of viruses causing influenza-like illnesses(ILI) among participants in a randomised controlled trial at the Hajj 2013. We recruited 1038 pilgrims from Saudi Arabia, Australia and Qatar during the first day of Hajj and followed them closely for four days. A nasal swab was collected from each pilgrim who developed ILI. Respiratory viruses were detected using multiplex RT-PCR. ILI occurred in 112/1038(11%) pilgrims. Their mean age was 35 years, 49(44%) were male and 35(31%) had received the influenza vaccine pre-Hajj. Forty two(38%) pilgrims had laboratory-confirmed viral infections; 28(25%) rhinovirus, 5(4%) influenza A, 2(2%) adenovirus, 2(2%) human coronavirus OC43/229 E, 2(2%) parainfluenza virus 3, 1(1%) parainfluenza virus 1, and 2(2%) dual infections. No MERS-Co V was detected in any sample. Rhinovirus was the commonest cause of ILI among Hajj pilgrims in 2013. Infection control and appropriate vaccination are necessary to prevent transmission of respiratory viruses at Hajj and other mass gatherings. | Osamah Barasheed Harunor Rashid Mohammad Alfelali Mohamed Tashani Mohammad Azeem Hamid Bokhary Nadeen Kalantan Jamil Samkari Leon Heron Jen Kok Janette Taylor Haitham El Bashir Ziad A.Memish Elizabeth Haworth Edward C.Holmes Dominic E Dwyer Atif Asghar Robert Booy | 2014 | Virologica Sinica2014，29，6： | 3 |
| 16 | Anti-inflammatory activity of the leaf extacts of Gendarussa vulgaris Nees显示文摘Objective:To evaluate the anti-inflammatory property of the leaf exacts of Gendarussa vulgaris(G.vulgarix) Nees.Methods:G.vulgarix Nees of the family Apocynaceae is a medium sized tree grown in semishade or no shade and is common in the Ernad and Nilambur taluks of Kerala. Various parts of this plant have been used in the treatment of ulcers,sores,inflammation, dyspepsia,healing of wounds,etc.The present study aimed at the evaluation of anti-inflammatory property of the aqueous and alcoholic extracts of the leaves by both in vitro and in vivo methods. In vitro method was estimated by human red blood cell membrane stabilisation(HRBC) method and in vivo method was estimated on the carrageenan induced paw oedima.Results:Both the methods showed significant anti-inflammatory property of the different extracts tested. Conclusions:The alcoholic extract at a concentration of 300 mg/mL showed potent activity on comparing with the standard drug diclofenac sodium. | TK Mohamed Saleem AK Azeem C Dilip C Sankar NV Prasanth R Duraisami | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，2： | 3 |
| 17 | Hepatocellular injury and the mortality risk among patients with COVID-19: A retrospective cohort study显示文摘BACKGROUND Clearly,infection with severe acute respiratory syndrome coronavirus 2 is not limited to the lung but also affects other organs.We need predictive models to determine patients’prognoses and to improve health care resource allocation during the coronavirus disease 2019(COVID-19)pandemic.While treating COVID-19,we observed differential outcome prediction weights for markers of hepatocellular injury among hospitalized patients.AIM To investigate the association between hepatocellular injury and all-cause inhospital mortality among patients with COVID-19.METHODS This multicentre study employed a retrospective cohort design.All adult patients admitted to Al-Azhar University Hospital,Assiut,Egypt and Abo Teeg General Hospital,Assiut,Egypt with confirmed COVID-19 from June 1,2020,to July 30,2020 were eligible.We categorized our cohort into three groups of(1)patients with COVID-19 presenting normal aminotransferase levels;(2)patients with COVID-19 presenting one-fold higher aminotransferase levels;and(3)patients with COVID-19 presenting two-fold higher aminotransferase levels.We analysed the association between elevated aminotransferase levels and all-cause in-hospital mortality.The survival analysis was performed using the Kaplan–Meier method and tested by log-rank analysis.RESULTS In total,376 of 419 patients met the inclusion criteria,while 29(8%)patients in our cohort died during the hospital stay.The median age was 40 years(range:28-56 years),and 51%were males(n=194).At admission,54%of the study cohort had liver injury.The pattern of liver injury was hepatocellular injury with an aspartate aminotransferase(AST)predominance.Admission AST levels were independently associated with all-cause in-hospital mortality in the logistic regression analysis.A one-fold increase in serum AST levels among patients with COVID-19 led to an eleven-fold increase in in-hospital mortality(P<0.001).Admission AST levels correlated with C-reactive protein(r=0.2;P<0.003)and serum ferritin(r=0.2;P<0.0002)levels.Admission alanine aminotransferase levels correlated with serum ferritin levels(r=0.1;P<0.04).Serum total bilirubin levels were independently associated with in-hospital mortality in the binary logistic regression analysis after adjusting for age and sex but lost its statistical significance in the fully adjusted model.Serum ferritin levels were significantly associated with in-hospital mortality(P<0.01).The probability of survival was significantly different between the AST groups and showed the following order:a two-fold increase in AST levels>a one-fold increase in in AST levels>normal AST levels(P<0.0001).CONCLUSION Liver injury with an AST-dominant pattern predicts the severity of COVID-19.Elevated serum ferritin levels are associated with fatal outcomes. | Ali Madian Ahmed Eliwa Hytham Abdalla Haitham A Azeem Aly | 2021 | World Journal of Hepatology2021，13，8： | 3 |
| 18 | QTL Mapping for Adult Plant Resistance to Powdery Mildew in Italian Wheat cv. Strampelli显示文摘The Italian wheat cv.Strampelli displays high resistance to powdery mildew caused by Blumeria graminis f.sp.tritici.The objective of this study was to map quantitative trait loci(QTLs) for resistance to powdery mildew in a population of 249 F 2:3 lines from Strampelli/Huixianhong.Adult plant powdery mildew tests were conducted over 2 yr in Beijing and 1 yr in Anyang and simple sequence repeat(SSR) markers were used for genotyping.QTLs Qpm.caas-3BS,Qpm.caas-5BL.1,and Qpm.caas-7DS were consistent across environments whereas,Qpm.caas-2BS.1 found in two environments,explained 0.4-1.6,5.5-6.9,27.1-34.5,and 1.0-3.5% of the phenotypic variation respectively.Qpm.caas-7DS corresponded to the genomic location of Pm38/Lr34/Yr18.Qpm.caas-4BL was identified in Anyang 2010 and Beijing 2011,accounting for 1.9-3.5% of phenotypic variation.Qpm.caas-2BS.1 and Qpm.caas-5BL.1 contributed by Strampelli and Qpm.caas-3BS by Huixianhong,seem to be new QTL for powdery mildew resistance.Qpm.caas-4BL,Qpm.caas-5BL.3,and Qpm.caas-7DS contributed by Strampelli appeared to be in the same genomic regions as those mapped previously for stripe rust resistance in the same population,indicating that these loci conferred resistance to both stripe rust and powdery mildew.Strampelli could be a valuable genetic resource for improving durable resistance to both powdery mildew and stripe rust in wheat. | Asad Muhammad Azeem BAI Bin LAN Cai-xia YAN Jun XIA Xian-chun ZHANG Yong HE Zhong-hu | 2013 | Journal of Integrative Agriculture2013，12，5： | 3 |
| 19 | 基于双变压器的复合式谐振三电平零电流开关变换器显示文摘针对分布式光伏发电接入中压直流配电网的应用场合,提出了一种基于双变压器的复合式谐振三电平变换器。新型变换器是在传统中性点钳位型三电平电路的基础上,通过添加一个辅助电路实现了基础三电平电路的固定占空比运行,变换器工作于电流断续模式。其中,基础三电平电路传输大部分功率,而辅助电路采用脉宽调制方式,可以实现基础三电平电路在全负载范围内的零电流开关,从而显著降低变换器的开关损耗。重点讨论了辅助变压器变比和谐振电容对开关管电流、谐振电压峰值、谐振电感值大小的影响,提出了相应的参数设计指导原则。最后,制作了一套300~1500V/2kW原理样机对所提变换器的性能进行了验证。 | 潘志新 宁光富 袁栋 付慧 随顺科 Waqar Azeem SYED | 2019 | 电力系统自动化2019，43，11： | 3 |
| 20 | Review on materials & methods to produce controlled release coated urea fertilizer显示文摘 | Babar Azeem KuZilati KuShaari Zakaria B. Man Abdul Basit Trinh H. Thanh | 2014 | Journal of Controlled Release2014，，： | 2 |
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