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| 1 | Intrahepatic biliary cystic neoplasms:Surgical results of 9 patients and literature review显示文摘AIM: To investigate the eligible management of the cystic neplasms of the liver. METHODS: The charts of 9 patients who underwent surgery for intrahepatic biliary cystic liver neoplasms between 2003 and 2008 were reviewed retrospectively. Informed consent was obtained from the patients and approval was obtained from the designated review board of the institution. RESULTS: All patients were female with a median (range) age of 49 (27-60 years). The most frequent symptom was abdominal pain in 6 of the patients. Four patients had undergone previous laparotomy (with other diagnoses) which resulted in incomplete surgery or recurrences. Liver resection (n = 6) or enucleation (n = 3) was performed. The final diagnosis was intrahepaticbiliary cystadenoma in 8 patients and cystadenocarcinoma in 1 patient. All symptoms resolved after surgery. There has been no recurrence during a median (range) 31 (7-72) mo of follow up. CONCLUSION: In spite of the improvement in imaging modalities and increasing recognition of biliary cystadenoma and cystadenocarcinoma, accurate preoperative diagnosis may be difficult. Complete surgical removal (liver resection or enucleation) of these lesions yields satisfying long-term results. | Ali Emre Kür■at Rahmi Serin Ilgin zden Yaman Tekant Orhan Bilge Ayd■n Alper Mine Güllüoglu Koray Güven | 2011 | World Journal of Gastroenterology2011，17，3： | 15 |
| 2 | SLC26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct显示文摘Pendred syndrome(PS) is characterized by autosomal recessive inheritance of goiter associated with a defect of iodide organification, hearing loss, enlargement of the vestibular aqueduct(EVA), and mutations of the SLC26A4 gene. However, not all EVA patients have PSor SLC26A4 mutations. Two mutant alleles of SLC26A4 are detected in 1/4 of North American or European EVA populations, one mutant allele is detected in another 1/4 of patient populations, and no mutations are detected in the other 1/2. The presence of two mutant alleles of SLC26A4 is associated with abnormal iodide organification, increased thyroid gland volume, increased severity of hearing loss, and bilateral EVA. The presence of a single mutant allele of SLC26A4 is associated with normal iodide organification, normal thyroid gland volume, less severe hearing loss and either bilateral or unilateral EVA. When other underlying correlations are accounted for, the presence of a cochlear malformation or the size of EVA does not have an effect on hearing thresholds. This is consistent with observations of an Slc26a4 mutant mouse model of EVA in which hearing loss is independent of endolymphatic hydrops or inner ear malformations. Segregation analyses of EVA in families suggest that the patients carrying one mutant allele of SLC26A4 have a second, undetected mutant allele of SLC26A4, and the probability of a sibling having EVA is consistent with its segregation as an autosomal recessive trait. Patients without any mutations are an etiologically heterogeneous group in which siblings have a lower probability of having EVA. SLC26A4 mutation testing can provide prognostic information to guide clinical surveillance and management, as well as the probability of EVA affecting a sibling. | Taku Ito Julie Muskett Parna Chattaraj Byung Yoon Choi Kyu Yup Lee Christopher K Zalewski Kelly A King Xiangming Li Philine Wangemann Thomas Shawker Carmen C Brewer Seth L Alper Andrew J Griffith | 2013 | World Journal of Otorhinolaryngology2013，3，2： | 2 |
| 3 | Manifestation of internal solitary waves on ERS SAR and SPOT images:Similarities and differences显示文摘 | Mitnik L Alpers W Chen K S | 2000 | Ieee 2000 International Geoscience and Remote Sensing Symposium2000，，： | 1 |
| 4 | Differential expression of cyclin-dependent kinase inhibitors in human glomerular disease: role in podocyte proliferation and maturation显示文摘 | Shankland S J Eimer F Hudkins K L Goodpaster T D' Agati V Alpers C E | 2000 | Kidney Int2000，58，： | 1 |
| 5 | Epidemiological studies of Epstein-Barr herpesvirus infection in Western Australia显示文摘 | Lai P K Mackay-Scollay E M Alpers M P | 1975 | J Hyg1975，74，3： | 1 |
| 6 | Myo- cardial infarction rardefined: a consensus doncument of the re - dryintition krmyocardial infovrction 显示文摘 | Alper JS Thygesen K Antman E et a| | 2011 | J AM Coll Caidiol2011，36，： | 1 |
| 7 | Primary adrenal non-Hodgkin's lymphoma:Report of two cases 显示文摘 | Ali E Alper P Emrah K | 2011 | Turk J Gastroenterol2011，22，6： | 1 |
| 8 | Intrapleural hyperthermic perfusion chemotherapy in subjects with metastatic pleural malignancies显示文摘 | Ahmet Feridun I??k Maruf ?anl? Miray Y?lmaz Fatih Metero?lu ?ner Dikensoy Alper Sevin? Celaletdin Camc? Bülent Tun??zgür Levent Elbeyli | 2013 | Respiratory Medicine2013，，： | 1 |
| 9 | Pirani Vacuum Gauges Using Silicon on Glass and Dissolved-Wafer Processes for the Char- acterization of MEMS Vacuum Packaging 显示文摘 | Topalli E S Topalli K Alper S M | 2009 | IEEE Sensors Journal2009，9，3： | 1 |
| 10 | A high-throughput screen for hyaluronic acid accumulation in recombinant Escherichia coli transformed by libraries of engineered sigma factors显示文摘 | Yu H M Tyo K Alper H etal | 2008 | Biotechnol Bioeng2008，101，4： | 1 |
| 11 | Membranes of poly(ether imide) and nanodispersed silica显示文摘 | S.P Nunes K.V Peinemann K Ohlrogge A Alpers M Keller A.T.N Pires | 1999 | Journal of Membrane Science1999，，2： | 1 |
| 12 | Removal of unilateral endometri- omas isassociated with immediate and sustained reduction in o- varian reserve显示文摘 | Urman B Alper E Yakin K | 2013 | Reprod Biomed Online2013，27，： | 1 |
| 13 | A wide-bandwidth and high-sensitivity robust microgyroscope显示文摘 | Sahin K Sahin E Alper S E | 2009 | Journal of Microme- chanics and Microengineering2009，19，07： | 1 |
| 14 | Modulation of experimental mesangial proliferative nephritis by interferon-gamma显示文摘 | Johnson RJ Lombardi D Eng E Gordon K Alpers CE Priozl P | 1995 | Kidney Int1995，4，1： | 1 |
| 15 | Negative pH, efflorescent mineralogy, and consequences for environmental restoration at the Iron Mountain Superfund site, California 显示文摘 | Nordstrom D K Alpers C N | 1999 | Proc Natl Acad Sci1999，96，： | 1 |
| 16 | Digital computation of the fractional fourier transform显示文摘 | Haldun M O Orhan A M Alper K | 1996 | IEEE Transaction on Signal Processing1996，44，9： | 1 |
| 17 | Patient oriented and rubust automatic liver segmentation for pre-evaluation of liver transplantation显示文摘 | Alper S M Aykut K Guleser K D | 2008 | Computers in Biology and Medicine2008，38，7： | 1 |
| 18 | Anti-sense suppression of epidermal growthfactor receptor expression alters cellular proliferation, cell-adhesion and tumorignicity in ovarian cancer cells 显示文摘 | Alper O De Santis ML Stromberg K | 2000 | Int J Cancer2000，88，4： | 1 |
| 19 | Anti-sense suppression of epidermal growth factor expression alters cellular proliferation,cell-adhesion and tumorigenicity in ovarian cancer cells显示文摘 | Alper O De Santis ML Stromberg K | 2000 | Int J Cancer2000，88，4： | 1 |
| 20 | The impact responses and the finite element modeling of layered trapezoidal corrugated aluminum core and aluminum sheet interlayer sandwich structures显示文摘 | Cenk K?l??aslan Mustafa Güden ?smet Kutlay Odac? Alper Ta?demirci | 2013 | Materials and Design2013，，： | 1 |
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