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199篇 您的检索式:作者名="Alptekin"
    题名 作者 年代 出处 被引量
1非英语国家的英语教学中的文化问题显示文摘在国外就英语作为外语教学来说,人们特有两种截然不同的观点。其一,以英语为母语的教师认为,英语教学应当溶入英语国家的社会文化准则和价值观念,旨在培养双语和双重文化的人才。其二,进行英语教学的非英语国家坚持认为,英语教学应当脱离其民族文化背景,使需培养学习者的双语能力,并无必要强调双重文化教育。本文拟从认知、情感和文化数据方面探讨这两种观点,Margaret Alptekin 杨平 1995外语教学理论与实践1995,,1:130
2Constitutive STAT3 phosphorylation and IL-6/IL-10 co-expression are associated with impaired T-cell function in tuberculosis patients显示文摘T-cells critically contribute to protection against Mycobacterium tuberculosis infection,and impaired T-cell responses can lead to disease progression.Pro-inflammatory and immunosuppressive cytokines affect T-cells,and fine-tuned regulation of cytokine signaling via the Jak/STAT signaling pathways is crucial for appropriate T-cell function.Constitutive STAT3 phosphorylation as a consequence of aberrant cytokine signaling has been described to occur in pathognomonic T-cell responses in inflammatory and autoimmune diseases.We characterized blood samples from tuberculosis patients(n=28)and healthy contacts(n=28)from Ghana for M.tuberculosis-specific T-cell responses,constitutive cytokine production,and SOCS3 and pSTAT3 expression.Lentiviral modulation of primary CD4+T-cells was performed to determine the effects of SOCS3 on T-cell functions.T-cells from tuberculosis patients expressed higher levels of IL-10 and IL-6 and lower levels of T helper type(TH)17 cytokines after M.tuberculosis-specific stimulation compared to healthy contacts.In addition,tuberculosis patients had higher IL-10 and IL-6 levels in the supernatants of non-stimulated immune cells and plasma samples compared to healthy contacts.Notably,aberrant cytokine expression was accompanied by high constitutive pSTAT3 levels and SOCS3 expression in T-cells.Multivariate analysis identified an IL-6/IL-10 co-expression-based principal component in tuberculosis patients that correlated with high pSTAT3 levels.SOCS3 contributed to a regulatory component,and tuberculosis patients with high SOCS3 expression showed decreased TH1 cytokine expression and impaired IL-2-induced STAT5 phosphorylation.SOCS3 over-expression in primary CD4+T-cells confirmed the SOCS3 inhibitory function on IL-2-induced STAT5 phosphorylation.We conclude that constitutive pSTAT3 and high SOCS3 expression are influential factors that indicate impaired T-cell functions in tuberculosis patients.Kirstin Harling Ernest Adankwah Alptekin Güler Anthony Afum-Adjei Awuah Louis Adu-Amoah Ertan Mayatepek Ellis Owusu-Dabo Norman Nausch Marc Jacobsen 2019Cellular & Molecular Immunology2019,16,3:15
3真空辅助熔模铸造制备A6063/SiC-B_4C混杂复合材料(英文)显示文摘采用真空辅助熔模铸造技术制备A6063/SiC-B4C混杂复合材料。首先,采用平均粒径分别为60μm和55μm、质量比为85%和15%的SiC和B4C粉末制备圆柱形的SiC-B4C预制块。然后,将预制块放入圆柱形石膏粘结块熔模中,在真空辅助铸造机中将A6063铝熔体浸渗到预制块中。采用阿基米德方法测定预制块中的孔隙度。对制备的复合材料进行硬度测试、图像分析、SEM观察和EDX成分分析。结果表明,采用真空辅助熔模铸造技术,铝熔体能将够成功地浸渗到预制块中。Alptekin KISASOZ Kerem Altug GULER Ahmet KARAASLAN 2012Transactions of Nonferrous Metals Society of China2012,22,7:2
4Investigation of carbon contamination in lost foam castings of low carbon steel显示文摘Lost foam casting(LFC) process is a special casting method in which polymeric foam patterns with refractory coatings are utilized as a mould component. In this work, four types of foam: expandable polyethylene(EPE), expandable polypropylene(EPP) and expandable polystyrene(EPS) foams with two different densities were employed as pattern materials. LFC and conventional green sand mould casting methods were used to cast a low carbon steel, A216 Grade WCB. Both casting processes were carried out at 1,580 °C. Chemical analysis results showed that the carbon contamination level was high and was influenced by pattern type. Metallographic investigations revealed a significant increase in the percentage of pearlite phase in all LFC samples. Densities of manufactured samples were calculated in order to evaluate porosity of the products. It was determined that the densities of the LFC samples were lower than the green sand mould cast reference sample(RS). Vickers hardness tests were also carried out and increments in hardness values with increased carbon content was observed.Oznur Kilic Serhat Acar Alptekin Kisasoz Kerem Altug Guler 2018China Foundry2018,15,5:2
5T6热处理对触变锻造加低过热铸造制备的A356和A380铝合金的影响(英文)显示文摘研究T6热处理对触变锻造A356和A380铝合金的影响。采用低过热铸造(LSC)技术制备用于触变锻造的样品。为了获得等轴晶粒并防止枝晶生长,将样品在高于液相温度20°C时进行浇铸,将浇铸坯料再加热不同时间(20~80 min)后进行触变锻造,变形量为50%,再将触变锻造后的A356和A380铝合金样品进行T6热处理。用光学显微镜、能量弥散X射线谱仪、扫描电镜和布氏硬度仪对经触变锻造、固溶处理和时效处理后样品的显微组织和硬度变化进行检测。结果表明,T6热处理后合金的显微组织更均匀,并分别在A356和A380坯料中形成了新的析出相Mg_2Si和Al_2Cu。相应地,经过人工时效后,样品的硬度大幅度提高,A356铝合金的硬度达到HB 93,A380铝合金的硬度达到HB 120。Ridvan GECU Serhat ACAR Alptekin KISASOZ Kerem ALTUG GULER Ahmet KARAASLAN 2018Transactions of Nonferrous Metals Society of China2018,28,3:2
6Influence of solution treatment on microstructure, corrosion resistance, and oxidation behavior of cast G-NiCr28W alloy显示文摘G-NiCr28W is a nickel-based cast alloy. Its microstructure consists of nickel-rich matrix phase and chromium-rich eutectic carbides. The solution treatment process can provide homogenous microstructure and desired mechanical/thermal properties for G-NiCr28W alloy. However, the solution treatment process affects the corrosion resistance of the alloy and it causes metal loss due to the occurrence of oxidation at atmospheric conditions. Therefore, determining the changes in the properties of the G-NiCr28W is important. For this purpose, G-NiCr28W specimens were solution treated at 1,040 ℃, 1,100 ℃ and 1,160 ℃ for 1 h and 8 h, respectively. The microstructures of the solution-treated samples were characterized by optical microscopy, scanning electron microscopy, energy dispersive spectroscopy and X-ray diffraction analysis. Moreover, hardness, corrosion resistance and oxidation behaviors of the solution-treated samples were examined. The solution treatment process applied at 1,160 ℃ led to the formation of Fe_2W_2C blocky carbides, and hardness of the sample increased with the existence of blocky carbides, while corrosion resistance decreased. Furthermore, excessive metal loss occurred depending on oxidation due to the high process temperature at 1,160 ℃.Alptekin Kisasoz 2019China Foundry2019,16,1:2
7Interleukin- lbeta,tumor necrosis factor-alpha levels and neutrophil elastase activity in peri-implant crevicular fluid显示文摘Ataogtu H Alptekin N O Haliloglu S 2002Clin- ical Oral Implants Research2002,13,:1
8Energy Efficiency in Pumps显示文摘Kaya D Alptekin Yagmur E Suleyman Yigit K 2008Energy Conversion and Managerment2008,49,:1
9Effects of pattern coating and vacuum assistance on porosity of aluminium lost foam castings显示文摘Kerem Altug Guler Alptekin Kisasoz Ahmet Karaaslan 2014Russ J Non-Ferrous Met2014,55,5:1
10The question of culture: EFL teaching in non-English-speaking countries 显示文摘Alptekin C 1984ELTJournal1984,38,1:1
11AE response of 316L SS during SSR test under potentiostatic control 显示文摘Cakir A Tuncell S Alptekin A 1999Corrosion Science1999,41,:1
12Redefining multicompetence for bilingualism and ELF 显示文摘Alptekin C 2010International Journal of Applied Linguistics2010,20,1:1
13Is quali- ty of life associated with cognitive impairment in Schizo- phrenia? 显示文摘Alptekin K Akvardar Y Kivircik Akdede BB 2005Prog Neuropsychopharmacol Biol Psychiatry2005,29,2:1
14Target-language culture in EFL materials显示文摘 1993ELT Journal1993,47,2:1
15Target-language culture in EFL materials显示文摘Alptekin C 1993ELT Journal1993,,2:1
16Tc -99m HMPAO brain perfusion SPECT in drug- free obsessive -compulsive patients without depression 显示文摘ALPTEKIN K DEGIRMENCI B KIVIRCIK B 2001Psychiatry Res2001,107,1:1
17Current options inlocal anesthesia for groin hernia repairs显示文摘Kulacoglu H Alptekin A 2011Acta Chir lugosl2011,58,3:1
18Psychiatrists' awareness of adherence to antipsychotic medication in patients with schizophrenia: results from a survey conducted across Europe, the Middle East, and Africa显示文摘Olivares JM Alptekin K Azorin JM 2013Patient Prefer Adherence2013,7,:1
19Product planning in quality function deployment using a combined analytic network process and goal programming approach显示文摘KARSAK E E SOVER S ALPTEKIN S E 2002Computer & Industrial Engineering2002,47,1:1
20Efficacy of treal- ment with a kinesthetic ability training device on balance and mobility after stroke: a randomized controlled study显示文摘Alptekin N Gok H Geler-Kulcu D el al 2008Clinical Rehabilitation2008,22,101:1
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