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| 1 | Late biliary complications in human alveolar echinococcosis are associated with high mortality显示文摘AIM:To evaluate the incidence of late biliary complications in non-resectable alveolar echinococcosis(AE)under long-term chemotherapy with benzimidazoles.METHODS:Retrospective analysis of AE patients with biliary complications occurring more than three years after the diagnosis of AE.We compared characteristics of patients with and without biliary complications,analyzed potential risk factor for biliary complications and performed survival analyses.RESULTS:Ninety four of 148 patients with AE in Zurich had non-resectable AE requiring long-term benzimidazole chemotherapy,of which 26(28%)patients developed late biliary complications.These patients had a median age of 55.5(35.5-65)years at diagnosis of AE and developed biliary complications after 15(8.25-19)years of chemotherapy.The most common biliary complications during long-term chemotherapy were late-onset cholangitis(n=14),sclerosing cholangitis-like lesions(n=8),hepatolithiasis(n=5),affection of the common bile duct(n=7)and secondary biliary cirrhosis(n=7).Thirteen of the 26 patients had undergone surgery(including 12 resections)before chemotherapy.Previous surgery was a risk factor for late biliary complications in linear regression analysis(P=0.012).CONCLUSION:Late biliary complications can be observed in nearly one third of patients with non-resectable AE,with previous surgery being a potential risk factor.After the occurrence of late biliary complications,the median survival is only 3 years,suggesting that late biliary complications indicate a poor prognostic outcome. | Pascal Frei Benjamin Misselwitz Meher K Prakash Alain M Schoepfer Bettina M Prinz Vavricka Beat Müllhaupt Michael Fried Kuno Lehmann Rudolf W Ammann Stephan R Vavricka | 2014 | World Journal of Gastroenterology2014，20，19： | 5 |
| 2 | Phylogenetic identification and in situ detection of individual microbial cells without cultivation显示文摘 | Ammann R R Ludwig W Schleifer K H | 1995 | M icrobiol Rev1995，59，1： | 1 |
| 3 | Phylogenet- ic identification and in situ detection of individual microbial cells without cultivation 显示文摘 | AMMANN R R LUDWIG W SCHLEIFER K H | 1995 | Microbiological Reviews1995，59，1： | 1 |
| 4 | Time course of serial cystatin C levels in comparison with serum creatinine after application of radio- contrast media显示文摘 | Rickli H Benou K Ammann P | 2004 | Clin Nephrol2004，61，2： | 1 |
| 5 | Time course of serial cystatin C levels in comparison with serum creatinine after application of radiocontrast media显示文摘 | Rickli H Benou K Ammann P | 2004 | Clin Nephrol2004，62，3： | 1 |
| 6 | Updated results on intestinal neuronal dysplasia显示文摘 | Meier - Ruge WA Ammann K Bruder E | 2004 | Eur J Pediatr Surg2004，14，6： | 1 |
| 7 | Mutations of the cystic fibrosis gene in patients with chronic pancreatitis显示文摘 | Malik N Ammann RW | 2001 | Am J Gastroenterol2001，96，9： | 1 |
| 8 | Mutations of the cystic fibrosis gene in patients with chronic pancreatitis显示文摘 | Truninger K Malik N Ammann RW | 2001 | Am J Gastroenterol2001，96，9： | 1 |
| 9 | 显示文摘 | Truninger K Ammann RW Blum HE | 2001 | Swiss Med Weekly2001，131，： | 1 |
| 10 | Time course of serial cystatin C levels in comparison with serum creatinine after application of ra- diocontrast media显示文摘 | Rickli H Benou K Ammann P | 2004 | Clin Nephrol2004，62，3： | 1 |
| 11 | Effects of transgenic Pit - 1 overexpression on Calcium phosphate and bone metabolism 显示文摘 | SUZUKI A AMMANN P NISHIWAKI -YASUDA K | 2010 | J Bone Miner Metab2010，28，2： | 1 |
| 12 | Time course of serial cystatin C levels in comparison with serum creatinine after application of radioeontrast media显示文摘 | RICKLI H BENOU K AMMANN P | 2004 | Clin Nephrol2004，62，： | 1 |
| 13 | Quantification of pleural effusion : sonography versus radiography 显示文摘 | Eibenberger K L Dock W I Ammann M E | 1994 | Radiology1994，191，： | 1 |
| 14 | Updated results on intestinal neuronal dysplasia (INDB)显示文摘 | Meier-Ruge WA Ammann K Bruder E | 2004 | EurJ Pediatr Surg2004，14，6： | 1 |
| 15 | 人为强迫和自然强迫对近年来对流层顶高度变化的贡献显示文摘观测表明,自1979年以来对流层顶(平流层与对流层之间的界限)高度增加了数百米。在气候模式实验中,等量的增加也是显而易见的。气候模式实验表明,人为因素导致臭氧和均匀混合温室气体的变化,对1979-1999年对流层顶高度增加的影响占所有因素的80%。臭氧对平流层的冷却作用和均匀混合的温室气体对对流层的加热作用,使对流层顶高度增加。 | Santer B D Wehner M F Wigley T M L Sausen R Meehl G A Taylor K E Ammann C Arblaster J Washington W M Boyle J S Bru'ggemann W 杨双艳 | 2009 | 沙漠与绿洲气象2009，3，5： | 1 |
| 16 | Collective cell migration of smooth muscle and endothelial cells: impact of injury versus non-injury stimuli显示文摘 | Ammann KR DeCook K J Tran PL | 2015 | J Biol Eng2015，9，： | 1 |
| 17 | Embolism of a metallic clip:an unusual complication following laparoscopic cholecystectomy显示文摘 | Ammann K Kiesenebner J Gadenst?tter M | 2000 | Dig Surg2000，17，5： | 1 |
| 18 | Impact of neoadjuvant chemoradiation on anal sphincter function in patients with carcinoma of the mid rectum and low rectum显示文摘 | Ammann K Kirehmayr W Klaus A | 2003 | Arch Surg2003，138，： | 1 |
| 19 | Updated results on intestinal neuronal dysplasia (IND B)显示文摘 | Ammann K Bruder E | 2004 | Eur J Pediatr Surg2004，14，6： | 1 |
| 20 | Updated results of intestinal neuronal dysplasia (IND B)显示文摘 | Meier-Ruge W Ammann K Bruder E | 2004 | Eur J Pediatr Surg2004，14，6： | 1 |
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