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| 1 | Pulmonary vein stenosis:Etiology,diagnosis and management显示文摘Pulmonary vein stenosis(PVS) is rare condition characterized by a challenging diagnosis and unfavorable prognosis at advance stages. At present, injury from radiofrequency ablation for atrial fibrillation has become the main cause of the disease. PVS is characterized by a progressive lumen size reduction of one or more pulmonary veins that, when hemodynamically significant, may raise lobar capillary pressure leading to signs and symptoms such as shortness of breath, cough, and hemoptysis. Image techniques(transesophageal echocardiography, computed tomography, magnetic resonance and perfusion imaging) are essential to reach a final diagnosis and decide an appropriate therapy. In this regard, series from referral centers have shown that surgical and transcatheter interventions may improve prognosis. The purpose of this article is to review the etiology, assessment and management of PVS. | Pablo Pazos-López Cristina García-Rodríguez Alba Guitián-González Emilio Paredes-Galán María ángel De La Guarda álvarez-Moure Marta Rodríguez-álvarez José Antonio Baz-Alonso Elvis Teijeira-Fernández Francisco Eugenio Calvo-Iglesias Andrés íniguez-Romo | 2016 | World Journal of Cardiology2016，8，1： | 6 |
| 2 | Diffuse intestinal ganglioneuromatosis an uncommon manifestation of Cowden syndrome显示文摘Diffuse intestinal ganglioneuromatosis is a hamartomatous polyposis characterized by a disseminated, intramural or transmural proliferation of neural elements involving the enteric plexuses. It has been associated with MEN Ⅱ, neurofibromatosis type 1 and hamartomatous polyposis associated with phosphatase and tensin homolog mutation. We report the case of a female patient with a history of a breast and endometrial tumor who presented in a colonoscopy performed for rectal bleeding diffuse ganglioneuromatosis, which oriented the search for other characteristic findings of Cowden syndrome given the personal history of the patient. The presence of an esophagogastric polyposis was also noted. Cowden syndrome is characterized by skin lesions, but it is rarely diagnosed by these lesions, because they are usually overlooked. Intestinal polyposis is not a major diagnostic criterion but it is very useful for early diagnosis. The combination of colonic polyposis and glucogenic acanthosis should orient the diagnosis to Cowden syndrome. | Maria Teresa Herranz Bachiller Jesus Barrio Andrés Fernando Pons Noelia Alcaide Suárez Rafael Ruiz-Zorrilla Lorena Sancho del Val Sara Lorenzo Pelayo Carlos De La Serna Higuera Ramon Atienza Sánchez Manuel Perez Miranda | 2013 | World Journal of Gastrointestinal Oncology2013，5，2： | 5 |
| 3 | Endosonography-guided drainage of pancreatic fluid collections with a novel lumen-apposing stent显示文摘 | Joan B. Gornals Carlos la Serna-Higuera Andrés Sánchez-Yague Carme Loras Andrés M. Sánchez-Cantos Manolo Pérez-Miranda | 2013 | Surgical Endoscopy2013，，4： | 4 |
| 4 | Risk factors for suicidal behaviour in late-life depression:A systematic review显示文摘BACKGROUND Suicide is a leading cause of preventable death worldwide,with its peak of maximum incidence in later life.Depression often puts an individual at higher risk for suicidal behaviour.In turn,depression deserves particular interest in old age due to its high prevalence and dramatic impact on health and wellbeing.AIM To gather integrated evidence on the potential risk factors for suicide behaviour development in depressive older adults,and to examine the effects of depression treatment to tackle suicide behaviour in this population.METHODS A systematic review of empirical studies,published from 2000 onwards,was conducted.Suicidal behaviour was addressed considering its varying forms(i.e.,wish to die,ideation,attempt,and completed suicide).RESULTS Thirty-five papers were selected for review,comprising both clinical and epidemiological studies.Most of studies focused on suicidal ideation(60%).The studies consistently pointed out that the risk was related to depressive episode severity,psychiatric comorbidity(anxiety or substance use disorders),poorer health status,and loss of functionality.Reduced social support and loneliness were also associated with suicide behaviour in depressive older adults.Finally,the intervention studies showed that suicidal behaviour was a robust predictor of depression treatment response.Reductions in suicidal ideation were moderated by reductions in risk factors for suicide symptoms.CONCLUSION To sum up,common and age-specific risk factors seem to be involved in suicide development in depressive older adults.A major effort should be made to tackle this serious public health concern so as to promote older people to age healthily and well. | Veronica Fernandez-Rodrigues Yolanda Sanchez-Carro Luisa Natalia Lagunas Laura Alejandra Rico-Uribe Andres Pemau Patricia Diaz-Carracedo Marina Diaz-Marsa Gonzalo Hervas Alejandro de la Torre-Luque | 2022 | World Journal of Psychiatry2022，12，1： | 3 |
| 5 | Involvement of serum retinoids and Leiden mutation in patients with esophageal, gastric, liver, pancreatic, and colorectal cancers in Hungary显示文摘AIM: To analyze the serum levels of retinoids and Leiden mutation in patients with esophageal, gastric, liver,pancreatic, and colorectal cancers.METHODS: The changes in serum levels of retinoids (vitamin A, α- and β-carotene, α- and β-cryptoxanthin,zeaxanthin, lutein) and Leiden mutation were measured by high liquid performance chromatography (HPLC)and polymerase chain reaction (PCR) in 107 patients (70 males/37 females) with esophageal (0/8), gastric (16/5), liver (8/7), pancreatic (6/4), and colorectal (30/21including 9 patients suffering from in situ colon cancer)cancer. Fifty-seven healthy subjects (in matched groups)for controls of serum retinoids and 600 healthy blood donors for Leiden mutation were used.RESULTS: The serum levels of vitamin A and zeaxanthin were decreased significantly in all groups of patients with gastrointestinal (GI) tumors except for vitamin A in patients with pancreatic cancer. No changes were obtained in the serum levels of α- and β-carotene,α- and β-cryptoxanthin, zeaxanthin, lutein in patients with GI cancer. The prevalence of Leiden mutation significantly increased in all groups of patients with GI cancer.CONCLUSION: Retinoids (as environmental factors)are decreased significantly with increased prevalence of Leiden mutation (as a genetic factor) in patients before the clinical manifestation of histologically different (planocellular and hepatocellular carcinoma, and adenocarcinoma) GI cancer. | Gyula Mózsik Gy(o|¨)rgy Rumi András D(o|¨)m(o|¨)t(o|¨)r Mária Figler Beáta Gasztonyi El(?)d Papp Alajos Pár Gabriella Pár József Belágyi Zoltán Matus Béla Melegh | 2005 | World Journal of Gastroenterology2005，11，48： | 2 |
| 6 | T HELPER 1/2 LYMPHOCYTE URINARY CYTOKINE PROFILES IN RESPONDING AND NONRESPONDING PATIENTS AFTER 1 AND 2 COURSES OF BACILLUS CALMETTE-GUERIN FOR SUPERFICIAL BLADDER CANCER显示文摘 | FABIEN SAINT JEAN J. PATARD PASCALE MAILLE PASCALE SOYEUX ANDRé HOZNEK LAURENT SALOMON ALEXANDRE DE LA TAILLE CLAUDE C. ABBOU DOMINIQUE K. CHOPIN | 2001 | The Journal of Urology2001，，6： | 1 |
| 7 | 基于SR7265硬件的虚拟锁相放大器、频谱仪、阻抗计和半导体参数分析仪(英文)显示文摘锁相放大器是用来测量微弱信号的专用仪器。即使噪音上千倍于被测信号,通过锁相放大器,也能得到精确结果。随着数字信号处理技术在仪器中的应用,可编程仪器变得越来越灵活。结合虚拟仪器的技术,论文通过对SR7265的硬件重新编程,在同一个硬件上实现了虚拟锁相放大器、虚拟频谱仪、虚拟阻抗计和虚拟半导体参数分析仪等等功能。本虚拟仪器采用了4层的逻辑结构。同样的功能也在一个FPGA板上成功地部署。 | 白江华 Freeouf L John Andres La Rosa | 2018 | Journal of Measurement Science and Instrumentation2018，9，1： | 1 |
| 8 | Potentially fatal bleeding in acute pancreatitis: pathophysiology,prevention,and treatment显示文摘 | Flati G Andrén-Sandberg A La Pinta M | 2003 | Pancreas2003，26，1： | 1 |
| 9 | In situ measurement of trace metals in lake water using the dialysis and DGT techniques显示文摘 | Maria Catalina Alfaro-De la Torre Pierre-Yves Beaulieu André Tessier | 2000 | Analytica Chimica Acta2000，418，1： | 1 |
| 10 | Solvent-free preparation of tris-pyrazolyl-1,3,5-triazines显示文摘 | Antonio de la Hoz Angel D??az-Ortiz José Elguero Luis J Mart??nez Andrés Moreno Ana Sánchez-Migallón | 2001 | Tetrahedron2001，，20： | 1 |
| 11 | Microwaves in organic synthesis: Thermal and non - thermal microwave effect 显示文摘 | Antonio de la Hoz Angel D Andres M | 2005 | Chemical Society Review2005，34，： | 1 |
| 12 | Increased amygdala and parahippocampal gyrus activation in schizophrenic patients with auditory hallucinations: An fMRI study using independent component analysis显示文摘 | María Jose Escartí Maria de la Iglesia-Vayá Luis Martí-Bonmatí Montserrat Robles Jose Carbonell Juan Jose Lull Gracián García-Martí Jose Vicente Manjón Eduardo Jesús Aguilar André Aleman Julio Sanjuán | 2010 | Schizophrenia Research2010，，1： | 1 |
| 13 | Reconstruction of the Burned Hand显示文摘 | Kreymerman PA Andres LA Lucas HD | 2011 | Plast Reconstr Surg2011，127，2： | 1 |
| 14 | FOLFIRI3-aflibercept in previously treated patients with metastatic colorectal cancer显示文摘AIM To evaluate the efficacy and safety of the modified FOLFIRI3-aflibercept as second-line therapy in patients with metastatic colorectal cancer.METHODS This is a retrospective multicenter cohort, evaluating the efficacy and safety of the association of aflibercept with FOLFIRI3(day 1: aflibercept 4 mg/kg, folinic acid 400 mg/m^2, irinotecan 90 mg/m^2, 5-fluorouracil infusion 2400 mg/m^2 per 46 h; day 3: irinotecan 90 mg/m^2) in patients with previously treated metastatic colorectal cancer. The primary endpoint was overall response rate(ORR). Secondary endpoints were disease control rate(DCR), progression-free survival(PFS), overall survival(OS), and safety.RESULTS Among 74 patients treated in four French centers, nine were excluded due to prior use of aflibercept(n = 3), more than one prior treatment line in irinotecanna?ve patients(n = 3), and inadequate liver function(n = 3). In the 'irinotecan-na?ve' patients(n = 30), ORR was 43.3% and DCR was 76.7%. Median PFS and OS were 11.3 mo(95%CI: 6.1-29.0) and 17.0 mo(95%CI: 13.0-17.3), respectively. The most common(> 5%) grade 3-4 adverse events were diarrhea(37.9%), neutropenia(14.3%), stomatitis and anemia(10.4%), and hypertension(6.7%). In the 'pre-exposed irinotecan' patients(n = 35), 20(57.1%) received ≥ 2 prior lines of treatment. ORR was 34.3% and DCR was 60.0%. Median PFS and OS were 5.7 mo(95%CI: 3.9-10.4) and 14.3 mo(95%CI: 12.8-19.5), respectively.CONCLUSION Minimally modified FOLFIRI has improvement dramatically the FOLFIRI3-aflibercept efficacy, whatever prior use of irinotecan. A prospective randomized trial is warranted to compare FOLFIRI-aflibercept to FOLFIRI3-aflibercept. | CANDice Carola Fran?ois Ghiringhelli Stefano Kim Thierry ANDré Juliette Barlet Le?la Bengrine-Lefevre Hélène Marijon Marie-Line Garcia-Larnicol Christophe Borg Linda Dainese Nils Steuer Hubert Richa Magdalena Benetkiewicz Annette K Larsen Aimery de Gramont Benoist Chibaudel | 2018 | World Journal of Clinical Oncology2018，9，5： | 1 |
| 15 | Double-blind placebo-controlled evaluation of sublingual-swallow immunotherapy with standardized Parietaria judaica extract in children with allergic rhinoconjunctivitis显示文摘 | La Rosa M Ranno C Andr'e C | 1999 | J Allergy Clin Immunoi1999，104，： | 1 |
| 16 | Neutrophil Gelatinase-Associated Lipocalin Is a Novel Mineralocorticoid Target in the Cardiovascular System显示文摘 | Celine Latouche Soumaya El Moghrabi Smail Messaoudi Aurélie Nguyen Dinh Cat Ivan Hernandez-Diaz Diego Alvarez de la Rosa Claudine Perret Natalia López Andrés Patrick Rossignol Faiez Zannad Nicolette Farman Frederic Jaisser | 2012 | Hypertension2012，，： | 1 |
| 17 | The effect of the obstetrician group and epidural analgesia on the risk for cesarean delivery in nulliarous women 显示文摘 | Beilin Y Friedman Jr F Andres LA | 2000 | Acta Anaesthesiol Scand2000，44，： | 1 |
| 18 | Micro-pumping flow system for spectrophotometric determination of anionic surfactants in water 显示文摘 | Andre F Lavorante Angel Morales-Rubio Miguel de la Guardia | 2005 | Anal Bioanal Chem2005，381，： | 1 |
| 19 | High-performance liquid chromatography method using ultraviolet detection for the quantification of aripiprazole and dehydroaripiprazole in psychiatric patients显示文摘 | Pedro Dorado Fernando de Andrés María Eugenia G. Naranjo Eva M. Pe?as-Lledó Idilio González Antonio P. González Alfredo de la Rubia Adrián LLerena | 2012 | Drug Metabolism and Drug Interactions2012，，3： | 1 |
| 20 | Influence of Flap Prefabrication on Seeding of Subcutaneously Injected Mesenchymal Stem Cells in Microvascular Beds in Rats显示文摘 | Andrés Rodríguez-Lorenzo María C. Arufe Alexandre de la Fuente Fernando Fernandez Francisco Blanco | 2014 | Annals of Plastic Surgery2014，，2： | 1 |
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