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116篇 您的检索式:作者名="Angelo R M"
    题名 作者 年代 出处 被引量
1一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P 2014中华神经外科疾病研究杂志2014,13,5:6
2Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A recep- tom显示文摘MANIYKTA P K ANGELO O R MATHEUS M R 2004Nemvscience Letters2004,355,:1
3Proposed refinement to the superpave high temperature specification parameter for performance graded binder 显示文摘Bouldin M G Dongre R D'Angelo J 2001Transportation Research Record2001,,1766:1
4Hydrodynamical modeling of charge carrier transport in semiconductors显示文摘Angelo M A Vittorio R 2000Overviews and Tutorials2000,35,:1
5Anticoagulant and aspirin prophylaxis for preventing thromboembolism after major gynecological surgery显示文摘Oates-Whitehead R M DAngelo A Mol B 2004Br J Perioper Nurs2004,14,7:1
6Lipid oxi-dation in foods显示文摘Vercellotti J R Angelo A J S Spanier A M 1996Critical Reviews in Food Scienceand Nutrition1996,36,3:1
7Two-level quantum dynamics,integrability and unitary NOT gates显示文摘Angelo R M Wreszinski W E 2005Phys Rev A2005,72,03:1
8Biogeochemical indicators to evaluate pollutant removal efficiency in constructed wetlands 显示文摘Reddy K R D'Angelo E M 1997Water Science and Technology1997,35,:1
9Biogeochemical indicators to evalute pollutant removal efficiency in Constructed wetlands显示文摘REDDY K R D'ANGELO E M 1997Wat Sci Tech1997,35,5:1
10Management of trauma-induced coagulopathy: trends and practices 显示文摘D'Angelo M R Dutton R P 2010AANA J2010,78,1:1
11Spatial patterns of nitrogen mineralization, fertilizer distribution and roots explain nitrate leaching from mature Amazonian oil palm plantation显示文摘Schroth G Rodrigues M R L D'Angelo S A 2000Soil Use and Management2000,16,3:1
12Extracorporeal circulation as a new experimental pathway for myoblast implantation in mdx mice显示文摘 Del Bo R 1999Cell Transplant1999,8,3:1
13Chemical and instrumental analysis of warmed- over flovor in beel显示文摘ST Angelo AJ Vercellotti J R Legendre M G 1987J Food Sci1987,52,:1
14Dividend Policy and the Earned/Contributed Capital Mix: A Test of the Life-Cycle Theory显示文摘De Angelo H L De Angelo Stulz R M 2006Journal of Financial Economics2006,,81:1
15Biogeochemical indicators to evaluate pollutant removal efficiency in constructed wetlands显示文摘 D'Angelo E M 1997Water Science and Technology1997,35,5:1
16Highly expanded flashing liquid jets 显示文摘Simoes-Moreira J R Vieira M M Angelo E 2002J Thermophysics and Heat Transfer2002,16,:1
17Native human adipose stremal cells: localization, morphology and phenotype 显示文摘Manmus M Peyrafitte JA D' Angelo R 2011Int J Obes2011,35,9:1
18Biogeochemical indicators to evaluate pollutant removal efficiency in constructed wetlands 显示文摘Reddy K R D 'Angelo E M 1997Water Science and Technology1997,35,5:1
19Biogeochemical indicators to evaluate pollutant removal efficiency in constructed wetlands 显示文摘Reddy K R D Angelo E M 1997Wat Sci Tech1997,35,:1
20Ammonium Oxidation and Nitrate Reduction in Sediment of a Hypereutrophic Lake 显示文摘D' Angelo E M Reddy K R 1993Soil Science Society American Journal1993,57,:1
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