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| 1 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 2 | Influence of fungal decay and moisture absorption on mechanical properties of extruded wood-plastic composites显示文摘 | Anke Schirp Michael P Wolcott | 2005 | Wood and Fiber Science2005，37，4： | 1 |
| 3 | Development of a rapid chromatographic strip test for the pen-side detection of foot-and-mouth disease virus antigen显示文摘 | Scott M Reid Nigel P Ferris Anke Bruning | 2001 | J Virol Methods2001，96，2： | 1 |
| 4 | Qccurrence of triiodinated X-ray contrast agents in the aquatic environment 显示文摘 | Anke P Wischnack S Jekel M | 2000 | Sci Total Environ2000，255，： | 1 |
| 5 | Development of a highly efficient gene targeting system for Fusarium graminearum using the disruption of a polyketide synthase gene as a visible marker显示文摘 | Frank J M Sascha M Anke P L | 2005 | FEMS Yeast Research2005，6，5： | 1 |
| 6 | Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: a comparison between hypoxia and inhibitors of cell显示文摘 | Anke H Torsten G Ulrich P | 2001 | J Cell Physiol2001，188，2： | 1 |
| 7 | Fungal degradation of wood-plastic composites and evaluation using dynamic mechanical analysis显示文摘 | Schirp Anke Wolcott Michael P | 2006 | Journal of Applied Polymer Science2006，99，6： | 1 |
| 8 | SISCOM in children with tuberous sclerosis complex-related epilepsy显示文摘 | Aboian MS Wong-Kisiel LC P ank M et a/ | 2011 | Pediatric Neurul2011，45，2： | 1 |
| 9 | An important role for type Ⅲ interferon (IFN-lambdaJ IL-28) in TLR-induced antiviral activity 显示文摘 | Ank N Iversen M B Bartholdy C P | 2008 | Journal of Immunology2008，180，4： | 1 |
| 10 | Simple method for the extraction and reversed-phase high-performance liquid chromatographic analysis of carotenoid pigments from red yeasts (Basidiomycota,Fungi)显示文摘 | R W S Weber H Anke P Davoli | | 0，，： | 1 |
| 11 | Effect of drying methods on volatiles of Chinese ginger (Zingiber offici- nale Roscoe)显示文摘 | DingSH AnK J Zhao C P | 2012 | Food and bioproducts processing2012，90，3： | 1 |
| 12 | CCR6 is required for IL-23-induced psoriasis-like inflammation in mice显示文摘 | Hedrick Michael N Lonsdorf Anke S Shirakawa Aiko-Konno Lee Chyi-Chia Richard Liao Fang Singh Satya P Zhang Hongwei H Grinberg Alexander Love Paul E Hwang Sam T Farber Joshua M | 2009 | Journal of Clinical Investigation2009，，8： | 1 |
| 13 | Exergetic evaluation of biomass gasification显示文摘 | Krzysztof J Mark J Anke P | 2007 | Energy2007，32，： | 1 |
| 14 | Isolation of expressed sequences that include a gene for familial breast cancer (BRCA2) and other transcripts from a five megabase region on chromosome 13q12显示文摘 | Geeta K Rajendra P K | 1996 | Oncogene1996，13，： | 1 |
| 15 | Adaptations of an orchid seed to water uptake and -storage 显示文摘 | Joachim P Anke S Rainer S 2000 | 2000 | Plant Systematics and Evolu- tion2000，220，12： | 1 |
| 16 | Influence of fungal decay and moisture absorption on mechanical properties of extruded wood-plastic composites显示文摘 | Anke Schirp Michael P Wolcott | 2005 | Wood and fiber science2005，37，4： | 1 |
| 17 | What can bacterial genome research teach us about bacteria–plant interactions?显示文摘 | Alfred Pühler Matthieu Arlat Anke Becker Michael G?ttfert John P Morrissey Fergal O’Gara | 2004 | Current Opinion in Plant Biology2004，，2： | 1 |
| 18 | A gene encoding a protein elicitor of Phytophthora infestans is down-regulated during infection of potato显示文摘 | Kamoun S Van West P De J ong Anke J | 1997 | Molecular Plant Microbe Interactions1997，10，1： | 1 |
| 19 | Neurological gait disorders in elderly people: clinical approach and classification显示文摘 | Anke H Snijders Bart P van de Warrenburg Nir Giladi Bastiaan R Bloem | 2006 | Lancet Neurology2006，，1： | 1 |
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