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3篇 您的检索式:作者名="Anna Picca"
    题名 作者 年代 出处 被引量
1Nonhydrolytic Route to Boron‐Doped TiO2 Nanocrystals显示文摘Hua Xu Rosaria Anna Picca Luisa De Marco Claudia Carlucci Angela Scrascia Paride Papadia Barbara Federica Scremin Elvio Carlino Cinzia Giannini Cosimino Malitesta Marco Mazzeo Giuseppe Gigli Giuseppe Ciccarella 2012Chem2012,,3:1
2Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding显示文摘Anna Picca Flavio Fracasso Vito Pesce Palmiro Cantatore Anna-Maria Joseph Christiaan Leeuwenburgh Maria Nicola Gadaleta Angela Maria Serena Lezza 2013AGE2013,,5:1
3Circulating extracellular vesicles:friends and foes in neurodegeneration显示文摘Extracellular vesicles have been identified as pivotal mediators of intercellular communication with critical roles in physiological and pathological conditions.Via this route,several molecules(e.g.,nucleic acids,proteins,metabolites) can be transferred to proximal and distant targets to convey specific information.Extracellular vesicle-associated cargo molecules have been proposed as markers of several disease conditions for their potential of tracking down the generating cell.Indeed,circulating extracellular vesicles may represent biomarkers of dysfunctional cellular quality control systems especially in conditions characterized by the accrual of intracellular misfolded proteins.Furthermore,the identification of extracellular vesicles as tools for the delivery of nucleic acids or other cargo molecules to diseased tissues makes these circulating shuttles possible targets for therapeutic development.The increasing interest in the study of extracellular vesicles as biomarkers resides mainly in the fact that the identification of peripheral levels of extracellular vesicle-associated proteins might reflect molecular events occurring in hardly accessible tissues,such as the brain,thereby serving as a 'brain liquid biopsy'.The exploitation of extracellular vesicles for diagnostic and therapeutic purposed might offer unprecedented opportunities to develop personalized approaches.Here,we discuss the bright and dark sides of extracellular vesicles in the setting of two main neurodegenerative diseases(i.e.,Parkinson's and Alzheimer's diseases).A special focus will be placed on the possibility of using extracellular vesicles as biomarkers for the two conditions to enable disease tracking and treatment monitoring.Anna Picca Flora Guerra Riccardo Calvani Hélio JoséCoelho-Junior Cecilia Bucci Emanuele Marzetti 2022Neural Regeneration Research2022,17,3:0
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