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10篇 您的检索式:作者名="Annat"
    题名 作者 年代 出处 被引量
1Effect of PEEP ventilation on re- nal function, plasma renin, aldosterone, neurophysins and urinary ADH, and prostaglandins显示文摘Annat G Viale JP Bui Xuan B 1983Anesthesiology1983,58,2:1
2Measuring the breathing workload in mechanically ventilated patients显示文摘Annat G Viale JP 1990Intensive Care Med1990,16,7:1
3: effect of clonidine显示文摘Quintin L Viale JP Annat G : Oxygen uptake after major abdominal surgery 1991Anesthesiology1991,74,:1
4The alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement显示文摘Shasta L Annat F Joseph DB 2001J Cell Biology2001,153,:1
5Anti-submarine weapons-the state of the art显示文摘Massimo Annat 2008Milliary Technology2008,,8:1
6Peptide-binding GRP78 protects neurons from hypoxia-induced apoptosis显示文摘Nitza Goldenberg-Cohen Annat Raiter Vera Gaydar Olga Dratviman-Storobinsky Tamar Goldstein Abraham Weizman Britta Hardy 2012Apoptosis2012,,3:1
7Oxygen uptake after major abdominal surgery:Effect of clonidine显示文摘Quintin L Viale JP Annat G 1991Anesthesiology1991,74,2:1
8Reversible self-polymerizing high Ts lyoprotectants 显示文摘MacFarlane D Pringle J Annat G 2002Cryobiology2002,45,2:1
9Oxygen uptake after major abdominal surgery: effect of clonidine 显示文摘Quintin L Viale JP Annat G 1991Anesthesiology1991,74,2:1
10GRP78 expression beyond cellular stress:A biomarker for tumor manipulation显示文摘Physiological stress takes place in the endoplasmic reticulum(ER) of cells where activation and up-regulation of genes and proteins are primarily induced to enhance pro-survival mechanisms such as the unfolded protein response(UPR).A dominant protein in the UPR response is the heat shock GRP78 protein.Although GRP78 is primarily located in the ER,under certain conditions it is transported to the cell surface,where it acts as a receptor inducing pathways of cell signaling such as proliferation or apoptosis.In the prolonged chronic stress transportation of the GRP78 from the ER to the cell membrane is a major event where in addition to the presentation of the GRP78 as a receptor to various ligands,it also marks the cells that will proceed to apoptotic pathways.In the normal cell that under stress acquires cell surface GRP78 and in the tumor cell that already presents cell surface GRP78,cell surface GRP78 is an apoptotic flag.The internalization of GRP78 from the cell surface in normal cells by ligands such as peptides will enhance cell survival and alleviate cardiovascular ischemic diseases.The absence of cell surface GRP78 in the tumor cells portends proliferative and metastatic tumors.Pharmacological induction of cell surface GRP78 will induce the process of apoptosis and might be used as a therapeutic modality for cancer treatment.Britta Hardy Annat Raiter 2015World Journal of Immunology2015,5,2:0
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