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8篇 您的检索式:作者名="Anne Caron"
    题名 作者 年代 出处 被引量
1Transcriptional Activation of Apolipoprotein CIII Expression by Glucose May Contribute to Diabetic Dyslipidemia显示文摘Sandrine Caron An Verrijken Ilse Mertens Carolina Huaman Samanez Gisèle Mautino Joel T. Haas Daniel Duran-Sandoval Janne Prawitt Sven Francque Emmanuelle Vallez Anne Muhr-Tailleux Isabelle Berard Folkert Kuipers Jan A. Kuivenhoven Sudha B. Biddinger Marja 2011Arteriosclerosis Thrombosis and Vascular Biology2011,,3:1
2Peroxisome Proliferator–Activated Receptor-α Gene Level Differently Affects Lipid Metabolism and Inflammation in Apolipoprotein E2 Knock-In Mice显示文摘Fanny Lalloyer Kristiaan Wouters Morgane Baron Sandrine Caron Emmanuelle Vallez Jonathan Vanhoutte Eric Baugé Ronit Shiri-Sverdlov Marten Hofker Bart Staels Anne Tailleux 2011Arteriosclerosis, Thrombosis, and Vascular Biology2011,,7:1
3Peroxisome Proliferator–Activated Receptor-α Gene Level Differently Affects Lipid Metabolism and Inflammation in Apolipoprotein E2 Knock-In Mice显示文摘Fanny Lalloyer Kristiaan Wouters Morgane Baron Sandrine Caron Emmanuelle Vallez Jonathan Vanhoutte Eric Baugé Ronit Shiri-Sverdlov Marten Hofker Bart Staels Anne Tailleux 2011Arteriosclerosis Thrombosis and Vascular Biology2011,,7:1
4Modification of nitrogen remobilization, grain fill and leaf senescence in maize (Zea mays) by transposon insertional mutagenesis in a protease gene显示文摘Iain S.Donnison Alan P.Gay HowardThomas Keith J.Edwards DavidEdwards Caron L.James Ann M.Thomas Helen J.Ougham 2006New Phytologist2006,,3:1
5Environmental perspectives of Blacks:Acceptance of the New Environmental Paradigm显示文摘CARON ANNE JUDI 1989Journal of Environmental Education1989,20,:1
6Selenium and the thyroid gland: more good news for clinicians显示文摘Anne Drutel Fran?oise Archambeaud Philippe Caron 2013Clin Endocrinol2013,,2:1
7An integrative approach of digital image analysis and transcriptome profiling to explore potential predictive biomarkers for TGFβblockade therapy显示文摘Increasing evidence suggests that the presence and spatial localization and distribution pattern of tumor infiltrating lymphocytes(TILs)is associate with response to immunotherapies.Recent studies have identified TGFβactivity and signaling as a determinant of T cell exclusion in the tumor microenvironment and poor response to PD-1/PD-L1 blockade.Here we coupled the artificial intelligence(AI)-powered digital image analysis and gene expression profiling as an integrative approach to quantify distribution of TILs and characterize the associated TGFβpathway activity.Analysis of T cell spatial distribution in the solid tumor biopsies revealed substantial differences in the distribution patterns.The digital image analysis approach achieves 74%concordance with the pathologist assessment for tumor-immune phenotypes.The transcriptomic profiling suggests that the TIL score was negatively correlated with TGFβpathway activation,together with elevated TGFβsignaling activity observed in excluded and desert tumor phenotypes.The present results demonstrate that the automated digital pathology algorithm for quantitative analysis of CD8 immunohistochemistry image can successfully assign the tumor into one of three infiltration phenotypes:immune desert,immune excluded or immune inflamed.The association between“cold”tumor-immune phenotypes and TGFβsignature further demonstrates their potential as predictive biomarkers to identify appropriate patients that may benefit from TGFβblockade.Robert Pomponio Qi Tang Anthony Mei Anne Caron Bema Coulibaly Joachim Theilhaber Maximilian Rogers-Grazado Michele Sanicola-Nadel Souad Naimi Reza Olfati-Saber Cecile Combeau Jack Pollard Tun Tun Lin Rui Wang 2022Acta Pharmaceutica Sinica B2022,12,9:0
8Moving beyond the opposition of diverse knowledge systems for food security and nutrition显示文摘Food Security and Nutrition(FSN) is influenced by diverse and complex factors, and therefore requires a holistic approach to agriculture and food systems plus integration of knowledge from diverse sources in science and society. Using the results of a colloquium held at the University of Hohenheim(Germany) in September 2016 leading up to the recent High Level Panel of Experts(HLPE) Note on Critical and Emerging Issues for Food Security and Nutrition, this article underlines the role of research and innovation as a social and political process and draws attention to neglected types of knowledge. It illustrates the potential of knowledge co-production and co-innovation to transform food systems in order to achieve the Sustainable Development Goals.Nathanaël PINGAULT Patrick CARON Alicia KOLMANS Stefanie LEMKE Carol KALAFATIC Sabine ZIKELI Ann WATERS-BAYER Carolin CALLENIUS QIN Yong-jun 2020Journal of Integrative Agriculture2020,19,1:0
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