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8篇 您的检索式:作者名="Anthony Mei"
    题名 作者 年代 出处 被引量
1Declines in the tuber‐feeding waterbird guild at Shengjin Lake National Nature Reserve, China – a barometer of submerged macrophyte collapse显示文摘Anthony D.Fox LeiCao YongZhang MarkBarter Mei JuanZhao Fan JuanMeng Si LongWang 2011Aquatic Conserv: Mar. Freshw. Ecosyst2011,,:3
2Increased Immune Reactivity Predicts Aggressive Complicating Crohn’s Disease in Children显示文摘Marla C. Dubinsky Subra Kugathasan Ling Mei Yoana Picornell Justin Nebel Iwona Wrobel Antonio Quiros Gary Silber Ghassan Wahbeh Lirona Katzir Eric Vasiliauskas Ron Bahar Anthony Otley David Mack Jonathan Evans Joel Rosh Maria Oliva Hemker Neal Leleiko Wal 2008Clinical Gastroenterology and Hepatology2008,,10:2
3Rapid Expansion of Human Hematopoietic Stem Cells by Automated Control of Inhibitory Feedback Signaling显示文摘Elizabeth Csaszar Daniel C. Kirouac Mei Yu WeiJia Wang Wenlian Qiao Michael P. Cooke Anthony E. Boitano Caryn Ito Peter W. Zandstra 2012Cell Stem Cell2012,,2:1
4Surrogate End Points and Long-Term Outcome in Patients With Chronic Hepatitis B显示文摘Vincent Wai–Sun Wong Grace Lai–Hung Wong Angel Mei–Ling Chim Paul Cheung–Lung Choi Anthony Wing–Hung Chan Steven Woon–Choy Tsang Alex Yui Hui Hoi–Yun Chan Joseph Jao–Yiu Sung Henry Lik–Yuen Chan 2009Clinical Gastroenterology and Hepatology2009,,10:1
5Assessment of Fibrosis by Transient Elastography Compared With Liver Biopsy and Morphometry in Chronic Liver Diseases显示文摘Grace Lai–Hung Wong Vincent Wai–Sun Wong Paul Cheung–Lung Choi Anthony Wing–Hung Chan Richard Hoi–Leong Chum Henry Kai–Wing Chan Kenneth Ka–Ki Lau Angel Mei–Ling Chim Karen Ka–Lam Yiu Francis Ka–Leung Chan Joseph Jao–Yao Sung Henry Lik–Yuen Chan 2008Clinical Gastroenterology and Hepatology2008,,9:1
6Vitamin D status: Multifactorial contribution of environment, genes and other factors in healthy Australian adults across a latitude gradient显示文摘Robyn M. Lucas Anne-Louise Ponsonby Keith Dear Patricia C. Valery Bruce Taylor Ingrid van der Mei Anthony J. McMichael Michael P. Pender Caron Chapman Alan Coulthard Trevor J. Kilpatrick Jim Stankovich David Williams Terence Dwyer 2013Journal of Steroid Biochemistry and Molecular Biology2013,,:1
7Role of histone deacetylase inhibitor in the treatment of cancer显示文摘Shaoping Mei Anthony D Ulrich 2004J Int Onco2004,25,:1
8An integrative approach of digital image analysis and transcriptome profiling to explore potential predictive biomarkers for TGFβblockade therapy显示文摘Increasing evidence suggests that the presence and spatial localization and distribution pattern of tumor infiltrating lymphocytes(TILs)is associate with response to immunotherapies.Recent studies have identified TGFβactivity and signaling as a determinant of T cell exclusion in the tumor microenvironment and poor response to PD-1/PD-L1 blockade.Here we coupled the artificial intelligence(AI)-powered digital image analysis and gene expression profiling as an integrative approach to quantify distribution of TILs and characterize the associated TGFβpathway activity.Analysis of T cell spatial distribution in the solid tumor biopsies revealed substantial differences in the distribution patterns.The digital image analysis approach achieves 74%concordance with the pathologist assessment for tumor-immune phenotypes.The transcriptomic profiling suggests that the TIL score was negatively correlated with TGFβpathway activation,together with elevated TGFβsignaling activity observed in excluded and desert tumor phenotypes.The present results demonstrate that the automated digital pathology algorithm for quantitative analysis of CD8 immunohistochemistry image can successfully assign the tumor into one of three infiltration phenotypes:immune desert,immune excluded or immune inflamed.The association between“cold”tumor-immune phenotypes and TGFβsignature further demonstrates their potential as predictive biomarkers to identify appropriate patients that may benefit from TGFβblockade.Robert Pomponio Qi Tang Anthony Mei Anne Caron Bema Coulibaly Joachim Theilhaber Maximilian Rogers-Grazado Michele Sanicola-Nadel Souad Naimi Reza Olfati-Saber Cecile Combeau Jack Pollard Tun Tun Lin Rui Wang 2022Acta Pharmaceutica Sinica B2022,12,9:0
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