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| 1 | Laparoscopic gastric surgery for cancer: Where do we stand?显示文摘Gastric cancer poses a significant public health problem, especially in the Far East, due to its high incidence in these areas. Surgical treatment and guidelines have been markedly different in the West, but nowadays this debate is apparently coming to an end. Laparoscopic surgery has been employed in the surgical treatment of gastric cancer for two decades now, but with controversies about the extent of resection and lymphadenectomy. Despite these difficulties, the apparent advantages of the laparoscopic approach helped its implementation in early stage and distal gastric cancer, with an increase on the uptake for distal gastrectomy for more advanced disease and total gastrectomy. Nevertheless, there is no conclusive evidence about the laparoscopic approach yet. In this review article we present and analyse the current status of laparoscopic surgery in the treatment of gastric cancer. | Pantelis T Antonakis Hutan Ashrafian Alberto Martinez Isla | 2014 | World Journal of Gastroenterology2014，20，39： | 16 |
| 2 | Gardner's syndrome: A case report and review of the literature显示文摘Gardner's syndrome is an autosomal dominant disease characterized by the presence of colonic polyposis,osteomas and a multitude of soft tissue tumors. The syndrome may present at any age from 2 mo to 70 years with a variety of symptoms, either colonic or extracolonic.We present a case of a 11-year-old female patient with Gardner's syndrome who presented with a lumbar area desmoid tumor and treated with resection of the desmoid,restorative proctocolectomy and ileal pouch anal anastomosis,A review of the current literature has been performed. | C Fotiadis DK Tsekouras P Antonakis J Sfiniadakis M Genetzakis GC Zografos | 2005 | World Journal of Gastroenterology2005，11，34： | 10 |
| 3 | Pancreatic insulinomas:laparoscopic management显示文摘Insulinomas are rare pancreatic neuroendocrine tumors that are most commonly benign,solitary,and intrapancreatic. Uncontrolled insulin overproduction from the tumor produces neurological and adrenergic symptoms of hypoglycemia. Biochemical diagnosis is confirmed by the presence of Whipple's triad,along with corroborating measurements of blood glucose,insulin,proinsulin,C-peptide,β-hydroxybutyrate,and negative tests for hypoglycemic agents during a supervised fasting period. This is accompanied by accurate preoperative localization using both invasive and non-invasive imaging modalities. Following this,careful preoperative planning is required,with the ensuing procedure being preferably carried out laparoscopically. An integral part of the laparoscopic approach is the application of laparoscopic intraoperative ultrasound,which is indispensable for accurate intraoperative localization of the lesion in the pancreatic region. The extent of laparoscopic resection is dependent on preoperative and intraoperative findings,but most commonly involves tumor enucleation or distal pancreatectomy. When performed in an experienced surgical unit,laparoscopic resection is associated with minimal mortality and excellent long-term cure rates. Furthermore,this approach confers equivalent safety and efficacy rates to open resection,while improving cosmesis and reducing hospital stay. As such,laparoscopic resection should be considered in all cases of benign insulinoma where adequate surgical expertise is available. | Pantelis T Antonakis Hutan Ashrafian Alberto Martinez-Isla | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，16： | 8 |
| 4 | Effects of mycophenolate mofetil vs cyclosporine administration on graft survival and function after islet allotransplantation in diabetic rats显示文摘AIM: To develop an experimental model of islet allotransplantation in diabetic rats and to determine the positive or adverse effects of MMF as a single agent. METHODS: Thirty-six male Wistar rats and 18 male Lewis rats were used as recipients and donors respectively. Diabetes was induced by the use of streptozotocin (60 mg/kg) intraperitoneally. Unpurified islets were isolated using the collagenase digestion technique and transplanted into the splenic parenchyma. The recipients were randomly assigned to one of the following three groups: group A (control group) had no immunosuppression; group B received cyclosporine (CsA) (5 mg/kg); group C receivedmycophenolate mofetil (MMF) (20 mg/kg). The animalswere killed on the 12th d. Blood and grafted tissues were obtained for laboratory and histological assessment. RESULTS: Median allograft survival was significantly higher in the two therapy groups than that in the controls (10 and 12 d for CsA and MMF respectively vs 0 d for the control group, P<0.01). No difference in allograft survival between the CsA and MMF groups was found. However,MMF had less renal and hepatic toxicity and allowed weight gain.CONCLUSION: Monotherapy with MMF for immunosu ppression was safe in an experimental model of islet allotransplantation and was equally effective with cyclosporine, with less toxicity. | Constantin Fotiadis Paraskevi Xekouki Apostolos E Papalois PantelisT Antonakis Ioannis Sfiniadakis Dimitrios Flogeras Eleutheria Karampela George Zografos | 2005 | World Journal of Gastroenterology2005，11，18： | 7 |
| 5 | The dynamics of technological innovation:the case of the pharmaceutical industry显示文摘 | Basit Achilladelis Nichotas Antonakis | 2001 | Research Policy2001，，： | 1 |
| 6 | Repeated intraperitoneal instillation of levobupivacaine for the management of pain after laparoscopic cholecystectomy显示文摘 | Papadima A Lagoudianakis EE Antonakis P | 2009 | Surgery2009，146，3： | 1 |
| 7 | The dynamics of technological innovation: The case of the pharmaceutical industry显示文摘 | Basil Achilladelis Nicholas Antonakis | 2001 | Research Policy2001，30，： | 1 |
| 8 | The dynamics of technolo-gical innovation:the case of the pharmaceutical industry显示文摘 | Basil Achilladelis Nicholas Antonakis | 2001 | Research Policy2001，30，4： | 1 |
| 9 | Synthesis of glucose-chlorambucil derivatives and their recognition by the human GLUT1 glucose transporter显示文摘 | Halmos T Santarromana M Antonakis K | | 0，，： | 1 |
| 10 | Incidental finding of gallbladder carcinoma detected during or after laparoscopic cholecystectomy显示文摘 | Antonakis P Alexakis N Mylonaki D | 2003 | Eur J Surg Oncol2003，29，4： | 1 |
| 11 | In vitro differential effects of the antiglucocorticoid RU486 on the release of lymphokines from mitogen-activated normal human lymphocytes显示文摘 | Antonakis N Georgoulias V Margioris AN | 1994 | J Steroid Biochem Mol Biol1994，51，12： | 1 |
| 12 | Leadership and individual differences: At the cusp of a renaissance显示文摘 | Antonakis J Day D V and Schyns B | 2012 | Leadership Quarterly2012，23，4： | 1 |
| 13 | Leader distance: a review and a proposed theory 显示文摘 | Antonakis J Atwater L | 2002 | Leadership Quarterly2002，13，4： | 1 |
| 14 | Incidental finding of gallbladder carcinoma detected during or after laparoscopic cholecyst ectomy显示文摘 | Antonakis P Alexakis N Mylonaki D | 2003 | Eur J Surg Oncol2003，29，4： | 1 |
| 15 | What makes articles highly cited? 显示文摘 | ANTONAKIS J BASTARDOZ N LIU Y | 2014 | The Leadership Quarterly2014，25，1： | 1 |
| 16 | Incidental finding of gallbladder carcinoma detected during or after laparoscopic cholecystectomy显示文摘 | Antonakis P Aiexakis N Mylonaki D | 2003 | Eur J Surg Oncol2003，29，4： | 1 |
| 17 | Towards a polymeric binding mimic for cytochrome显示文摘 | Rathbone D L Ali A Antonaki P | 2005 | Biosensors and Bioelectronics2005，20，11： | 1 |
| 18 | Could lean production job design be intrinsically motivating? Contextual, configurational, and levels-of-analysis issues显示文摘 | Suzanne de Treville John Antonakis | 2005 | Journal of Operations Management2005，，2： | 1 |
| 19 | Does leadership need emotional intelligence?显示文摘 | John Antonakis Neal M. Ashkanasy Marie T. Dasborough | 2008 | The Leadership Quarterly2008，，2： | 1 |
| 20 | Incidental finding of gallbladder carcinoma detected during or after laparoscopic cholecystectom显示文摘 | ANTONAKIS P ALEXAKIS N MYLONAKI D | 2003 | European Journal of Surgical Oncology2003，29，： | 1 |
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