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| 1 | Gastric food retention at endoscopy is associated with severity of liver cirrhosis显示文摘BACKGROUND Gastrointestinal symptoms are prevalent in patients with cirrhosis.Cirrhotic patients have a known predilection to delayed gastric emptying compared to those without cirrhosis.However,the contributing factors have not been fully elucidated.Retained gastric food on esophagogastroduodenoscopy(EGD)has been used as a surrogate marker for delayed gastric emptying with reasonably high specificity.Therefore,we hypothesize that the frequency of retained gastric food contents at EGD will be higher in a cirrhotic population compared to a control population without liver disease.Additionally,we hypothesize that increased frequency of gastric food contents will be associated with increased severity of cirrhosis.AIM To determine the relative frequency of delayed gastric emptying among cirrhotics as compared to non-cirrhotics and to identify associated factors.METHODSWe performed a retrospective case-control study of cirrhotic subjects whounderwent EGD at an academic medical center between 2000 and 2015. Threehundred sixty-four patients with confirmed cirrhosis, who underwent a total of1044 EGDs for the indication of esophageal variceal screening or surveillance,were identified. During the same period, 519 control patients without liverdisease, who underwent a total of 881 EGDs for the indication of anemia, wereidentified. The presence of retained food on EGD was used as a surrogate fordelayed gastric emptying. The relative frequency of delayed gastric emptyingamong cirrhotics was compared to non-cirrhotics. Characteristics of patients withand without retained food on EGD were compared using univariable andmultivariable logistic regression analysis to identify associated factors.RESULTSOverall, 40 (4.5%) patients had evidence of retained food on EGD. Cirrhotics weremore likely to have retained food on EGD than non-cirrhotics (9.1% vs 1.4%, P <0.001). Characteristics associated with retained food on univariable analysisincluded age less than 60 years (12.6% vs 5.2%, P = 0.015), opioid use (P = 0.004),Child-Pugh class C (24.1% Child-Pugh class C vs 6.4% Child-Pugh class A, P =0.007), and lower platelet count (P = 0.027). On multivariate logistic regressionanalysis, in addition to the presence of cirrhosis (adjusted OR = 5.83;95%CI: 2.32-14.7, P < 0.001), diabetes mellitus (types 1 and 2 combined) (OR = 2.34;95%CI:1.08-5.06, P = 0.031), opioid use (OR = 3.08;95%CI: 1.29-7.34, P = 0.011), andChild-Pugh class C (OR = 4.29;95%CI: 1.43-12.9, P = 0.01) were also associatedwith a higher likelihood of food retention on EGD.CONCLUSIONCirrhotics have a higher frequency of retained food at EGD than non-cirrhotics.Decompensated cirrhosis, defined by Child-Pugh class C, is associated with ahigher likelihood of delayed gastric emptying. | David B Snell Shirley Cohen-Mekelburg Russell Weg Gaurav Ghosh Adam P Buckholz Amit Mehta Xiaoyue Ma Paul J Christos Arun B Jesudian | 2019 | World Journal of Hepatology2019，11，11： | 2 |
| 2 | Monitoring of black tea fermentation process using electronic nose显示文摘 | Nabarun Bhattacharyya Sohan Seth Bipan Tudu Pradip Tamuly Arun Jana Devdulal Ghosh Rajib Bandyopadhyay Manabendra Bhuyan | 2006 | Journal of Food Engineering2006，，4： | 2 |
| 3 | Studies on physicochemical characteristics of chitosan derivatives with dicarboxylic acids显示文摘 | Arun Ghosh M Azam Ali | 2012 | Journal of Materials Science2012，47，3： | 1 |
| 4 | I)e- sign, Synthesis, and X ray Structure of Potent Memapsin 2 (t3 Secretase) Inhibitors with Isophthalamide Derivatives as the P2 P3-- Ligands显示文摘 | Ghosh Arun Kumaragurubaran Nagaswamy Hong Lin | 2007 | J Med Chem2007，50，： | 1 |
| 5 | Replacement of virgin rubbers by waste ground vulcanizates in blends of silicone rubber and fluororubber based on tetrafluoroethylene/propylene/vinylidene fluoride terpolymer显示文摘 | Arun Ghosh P Antony | 2001 | Journal of Applied Polymer Science2001，82，： | 1 |
| 6 | Structure-based design: synthesis and biological evaluation of a series of novel cycloamide- derived HIV-1 protease inhibitors 显示文摘 | Arun K Ghosh Lisa M Swanson Hanna Cho Sofiya Leshehenko Khaja Azhar Hussain Stephanie Kay D Eric Walters Yasuhiro Koh Hiroaki Mitsuya | 2005 | Journal of medicinal chemistry2005，48，10： | 1 |
| 7 | Noradrenaline vs terlipressin in the treatment of type 2 hepatorenal syndrome: a randomized pilot study显示文摘 | Saubhik Ghosh Narendra S. Choudhary Arun K. Sharma Baljinder Singh Pradeep Kumar Ritesh Agarwal Navneet Sharma Ashish Bhalla Yogesh K. Chawla Virendra Singh | 2013 | Liver Int2013，，8： | 1 |
| 8 | Preemptive identification of optimum fermentation time for black tea using electronic nose显示文摘 | Nabarun Bhattacharya Bipan Tudu Arun Jana Devdulal Ghosh Rajib Bandhopadhyaya Manabendra Bhuyan | 2007 | Sensors & Actuators: B Chemical2007，，1： | 1 |
| 9 | Detection of optimum fermentation time for black tea manufacturing using electronic nose显示文摘 | Nabarun Bhattacharyya Sohan Seth Bipan Tudu Pradip Tamuly Arun Jana Devdulal Ghosh Rajib Bandyopadhyay Manabendra Bhuyan Santanu Sabhapandit | 2006 | Sensors & Actuators: B Chemical2006，，2： | 1 |
| 10 | Novel cyclourethane-derived HIV protease inhibitors: A ring-closing olefin metathesis based strategy显示文摘 | Ghosh Arun K Swanson Lisa M Liu Chunfeng | 2002 | Bioorganic and Medicinal Chemistry Letters2002，，12： | 1 |
| 11 | Detection of optimum fermentation time for black tea manufacturing using electronic nose显示文摘 | Nabarun Bhattacharyya Sohan Seth Bipan Tudu Pradip Tamuly Arun Jana Devdulal Ghosh Rajib Bandyopadhyay Manabendra Bhuyan Santanu Sabhapandit | 2006 | Sensors & Actuators: B Chemical2006，，2： | 1 |
| 12 | Monitoring of black tea fermentation process using electronic nose显示文摘 | Nabarun Bhattacharyya Sohan Seth Bipan Tudu Pradip Tamuly Arun Jana Devdulal Ghosh Rajib Bandyopadhyay Manabendra Bhuyan | 2006 | Journal of Food Engineering2006，，4： | 1 |
| 13 | Electronic nose for black tea quality evaluation by an incremental RBF network显示文摘 | Bipan Tudu Arun Jana Animesh Metla Devdulal Ghosh Nabarun Bhattacharyya Rajib Bandyopadhyay | 2009 | Sensors and Actuators B 1382009，，： | 1 |
| 14 | Preemptive identification of optimum fermentation time for black tea using electronic nose显示文摘 | Nabarun Bhattacharya Bipan Tudu Arun Jana Devdulal Ghosh Rajib Bandhopadhyaya Manabendra Bhuyan | 2008 | Sensors and Actuators B 1312008，，： | 1 |
| 15 | Interfacial polymerization of thin film nanocomposites: A new concept for reverse osmosis membranes显示文摘 | Byeong-Heon Jeong Eric M.V. Hoek Yushan Yan Arun Subramani Xiaofei Huang Gil Hurwitz Asim K. Ghosh Anna Jawor | 2007 | Journal of Membrane Science2007，，1： | 1 |
| 16 | Enteric Pathogens, Immune Status and Therapeutic Response in Diarrhea in HIV/AIDS Adult Subjects from North India显示文摘 | Arun Kumar Jha Beena Uppal Sanjim Chadha Prabhav Aggarwal Roumi Ghosh Richa Dewan | 2013 | Current HIV Research2013，，4： | 1 |
| 17 | Stereosdective photochemical 1,3-dioxolane addition to 5-alkoxymethyl-2 (5-H) -furanone: Synthesis of bis-tetrahydrofuranyl ligand for HIV protease inhibitor UIC-94017(TMC-114) 显示文摘 | Arun K Ghosh Sofiya Leshchenko Marcus Noetzel | 2004 | J Org Chem2004，69，23： | 1 |
| 18 | Agrobacterium-mediated Transformation of Brassica juncea with a Cyanobacterial (Synechocystis PCC6803) Delta-6 Desaturase Gene Leads to Production of Gamma-linolenic Acid显示文摘 | Biswajit Das Lily Goswami Sudipta Ray Shilpi Ghosh Sanghamitra Bhattacharyya Sampa Das Arun Lahiri Majumder | 2006 | Plant Cell Tissue and Organ Culture2006，，2： | 1 |
| 19 | Expression of accessory colonization factor subunit A (ACFA) of Vibrio cholerae and ACFA fused to cholera toxin B subunit in transgenic tomato ( Solanum lycopersicum )显示文摘 | Manoj Kumar Sharma Dewal Jani M. Thungapathra J.K. Gautam L.S. Meena Yogendra Singh Amit Ghosh Akhilesh Kumar Tyagi Arun Kumar Sharma | 2008 | Journal of Biotechnology2008，，1： | 1 |
| 20 | The antibacterial properties of a novel chitosan–Ag-nanoparticle composite显示文摘 | Pallab Sanpui A. Murugadoss P.V. Durga Prasad Siddhartha Sankar Ghosh Arun Chattopadhyay | 2008 | International Journal of Food Microbiology2008，，2： | 1 |
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