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| 1 | Atkins、Zone、Ornish和LEARN饮食对绝经后超重妇女体重及相关危险因素变化的影响——A TO Z减肥研究:随机试验显示文摘背景:时下盛行的饮食(尤其是低碳水化合物饮食)与当前推荐的低脂、高碳水化合物减肥饮食有所抵触。迄今为止,人们尚未充分研究不同饮食的潜在利弊。
目的:比较4种减肥饮食(代表着各种碳水化合物摄入量)对减肥及相关代谢指标的影响。
设计、地点及参试者:2003年2月至2005年10月在美国311名绝经后超重、肥胖(体重指数为27—40)妇女中开展为期12个月的随机试验,这些妇女生活自在,无糖尿病。 | Christopher D. Gardner Alexandre Kiazand Sofiya Alhassan 顾佳(译) | 2007 | 美国医学会杂志(中文版)2007，26，4： | 10 |
| 2 | Evaluation of fully covered self-expanding metal stents in benign biliary strictures and bile leaks显示文摘AIM: To investigate the use of fully covered metal stents in benign biliary strictures (BBS) and bile leaks. METHODS: We studied 17 patients, at Harbor-UCLA Medical center (Los Angeles), with BBS (n=12) and bile leaks (n=5) from July 2007 to February 2012 that had received placement of fully covered self-expanding metal stents (FCSEMs). Fourteen patients had endoscopic placement of VIABIL (Conmed, Utica, New York, United States) stents and three had Wallflex (Boston Scientific, Mass) stents. FCSEMS were 8 mm or 10 mm in diameter and 4 cm to 10 cm in length. Patients were followed at regular intervals to evaluate for symptoms and liver function tests. FCSEMS were removed after 4 or more weeks. Resolution of BBS and leak was documented cholangiographically following stent removal. Stent patency can be defined as adequate bile and contrast flow from the stent and into the ampulla during endoscopic retrograde cholangiopancreatography (ERCP) without clinical signs and/or symptoms of biliary obstruction. Criterion for bile leak resolution at ERCP is defined as absence of contrast extravasation from the common bile duct, cystic duct remanent, or gall blad-der fossa. Rate of complications such as migration, and instent occlusion were recorded. Failure of endoscopic therapy was defined as persistent biliary stenosis or continuous biliary leakage after 12 mo of stent placement. RESULTS: All 17 patients underwent successful FC- SEMS placement and removal. Etiologies of BBS included: cholecystectomies (n=8), cholelithiasis (n=2), hepatic artery compression (n=1), pancreatitis (n=2), and Whipple procedure (n=1). All bile leaks occurred following cholecystectomy. The anatomic location of BBS varied: distal common bile duct (n=7), common hepatic duct (n=1), hepaticojejunal anastomosis (n=2), right intrahepatic duct (n=1), and choledochoduo-denal anastomatic junction (n=1). All bile leaks were found to be at the cystic duct. Twelve of 17 patients had failed prior stent placement or exchange. Resolution of the biliary strictures and bile leaks was achieved in 16 of 17 patients (94%). The overall median stent time was 63 d (range 27-251 d). The median stent time for the BBS group and bile leak group was 62 ± 58 d (range 27-199 d) and 92 ± 81 d (range 48-251 d), respectively. All 17 patients underwent successful FCSEMS removal. Long term follow-up was obtained for a median of 575 d (range 28-1435 d). Complications occurred in 5 of 17 patients (29%) and included: migration (n=2), stent clogging (n=1), cholangitis (n=1), and sepsis with hepatic abscess (n=1). CONCLUSION: Placement of fully covered self-expanding metal stents may be used in the management of benign biliary strictures and bile leaks with a low rate of complications. | David Lalezari Inder Singh Sofiya Reicher Viktor Ernst Eysselein | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，7： | 8 |
| 3 | Structure-based design: synthesis and biological evaluation of a series of novel cycloamide- derived HIV-1 protease inhibitors 显示文摘 | Arun K Ghosh Lisa M Swanson Hanna Cho Sofiya Leshehenko Khaja Azhar Hussain Stephanie Kay D Eric Walters Yasuhiro Koh Hiroaki Mitsuya | 2005 | Journal of medicinal chemistry2005，48，10： | 1 |
| 4 | Rapid colorimetric detection of antibody-epitope recognition at a biomimetic membrane interface显示文摘 | RON K MARINA K | 2001 | Journal of the American Chemical Society2001，123，3： | 1 |
| 5 | Opioid Receptor Blockade Prevents Exercise - Associated Autonomic Failure in Humans显示文摘 | Sofiya Milman James Leu Harry Shamoon | 2012 | Diabetes2012，61，： | 1 |
| 6 | Determination of free levels of phenytoin in human plasma by liquid chromatography/tandem mass spectrometry显示文摘 | Sofiya B James CO Alan PB | 2000 | J Pharm Biomed Anal2000，23，23： | 1 |
| 7 | Opioid Receptor Blockade Prevents Exercise - Associated Autonomic Failure in Humans显示文摘 | Sofiya Milman James Leu Harry Shamoon | 2012 | Diabetes2012，61，： | 1 |
| 8 | Phenotypes and Genotypes of High Density Lipoprotein Cholesterol in Exceptional Longevity显示文摘 | Sofiya Milman Gil Atzmon Jill Crandall Nir Barzilai | 2014 | Current Vascular Pharmacology2014，，： | 1 |
| 9 | 库尔茨克铁矿床的环境矿物学(英文)显示文摘开发新技术是解决与铁矿选矿有关的环境问题的有效途径。综合性矿物学研究有助于选矿过程的改进。笔者与IPKON研究所的专家们一起研究开发一种电化学的方法,以改善制备用于湿法磁选的矿粉的性质并研究了使用电化学方法前后样品的性状。采用扫描电镜(SEM)技术研究矿物颗粒表面,发现其在絮化作用中的差异;偏极化曲线的测定可以揭示磁铁矿、赤铁矿和假象赤铁矿等矿物表面的不均等电化学过程;X-射线分析和穆斯堡尔谱数据亦可确定电化学处理前后矿粉样品成分的变化。所研究样品的磁性,在采用该方法前后样品的对比揭示其在:磁粘滞性(Svo)、磁饱和场的破坏(Hcr)、磁化率(χ)、及磁化强度(Is)等参数的相应增大。 | Tatiana V. Posukhova Sofiya K. Riakhovskaya | 2008 | 地学前缘2008，15，6： | 1 |
| 10 | Mesoporous fibrous silicon nitride by catalytic nitridation of silicon显示文摘The catalytic effect of metal oxide/alumina whiskers(CeO2, Mn3O4, NiO, Co3O4, Fe2O3, Cr2O3/AW) was evaluated on their ability to drive the nitridation of silicon and to generate mesoporous fibrous silicon networks.Silicon powder with different particles size along with the catalyst was nitridized at 1300 ℃ for 5 h in nitrogen and nitrogen diluted with 10 vol% ammonia atmospheres. Nitridation degree of silicon up to 99% was recorded using 1.5 wt% CeO2 and Fe2O3 catalysts in nitrogen-ammonia atmosphere. The catalyzed samples contain submicronic silicon nitride fibres with a diameter of 400–500 nm and a length of up to few micrometers. The compressive strength of 46 ± 1 MPa was measured for silicon samples catalyzed with nickel oxide/alumina whiskers and nitridized in N2/10 vol%NH3 atmosphere. Porous silicon nitride networks were produced with 45–52% porosity, pore sizes in the range of 370–1200 nm and median pore in the range of 495–1655 nm. | Tatevik Minasyan Le Liu Marina Aghayan Miguel ARodriguez Sofiya Aydinyan Irina Hussainova | 2019 | Progress in Natural Science:Materials International2019，29，2： | 1 |
| 11 | Groucho homologue Grg5 interacts with the transcription factor Runx2–Cbfa1 and modulates its activity during postnatal growth in mice显示文摘 | WenFang Wang You-Gan Wang Anthony M Reginato Donald J Glotzer Naomi Fukai Sofiya Plotkina Gerard Karsenty Bjorn R Olsen | 2004 | Developmental Biology2004，，2： | 1 |
| 12 | Improved diagnostic yield of endoscopic ultrasound-fine needle biopsy with histology specimen processing显示文摘BACKGROUND Endoscopic ultrasound-guided fine needle biopsy(EUS-FNB)has emerged as a safe,efficacious alternative to fine needle aspiration(FNA)for tissue acquisition.EUS-FNB is reported to have higher diagnostic yield while preserving specimen tissue architecture.However,data on the optimal method of EUS-FNB specimen processing is limited.AIM To evaluate EUS-FNB with specimen processing as histology vs EUS-FNA cytology with regards to diagnostic yield and specimen adequacy.METHODS All EUS-FNA and EUS-FNB performed at our institution from July 1,2016,to January 31,2018,were retrospectively analyzed.We collected data on demographics,EUS findings,pathology,clinical outcomes,and procedural complications in two periods,July 2016 through March 2017,and April 2017 through January 2018,with predominant use of FNB in the second data collection time period.FNA specimens were processed as cytology with cell block technique and reviewed by a cytopathologist;FNB specimens were fixed in formalin,processed for histopathologic analysis and immunohistochemical staining,and reviewed by an anatomic pathologist.Final diagnosis was based on surgical pathology when available,repeat biopsy or imaging,and length of clinical follow up.RESULTS One hundred six EUS-FNA and EUS-FNB procedures were performed.FNA alone was performed in 17 patients;in 56 patients,FNB alone was done;and in 33 patients,both FNA and FNB were performed.For all indications,diagnostic yield was 47.1%(8/17)in FNA alone cases,85.7%(48/56)in FNB alone cases,and 84.8%(28/33)in cases where both FNA and FNB were performed(P=0.0039).Specimens were adequate for pathologic evaluation in 52.9%(9/17)of FNA alone cases,in 89.3%(50/56)of FNB alone cases,and 84.8%(28/33)in cases where FNA with FNB were performed(P=0.0049).Tissue could not be aspirated for cytology in 10.0%(5/50)of cases where FNA was done,while in 3.4%(3/89)of FNB cases,tissue could not be obtained for histology.In patients who underwent FNA with FNB,there was a statistically significant difference in both specimen adequacy(P=0.0455)and diagnostic yield(P=0.0455)between the FNA and FNB specimens(processed correspondingly as cytology or histology).CONCLUSION EUS-FNB has a higher diagnostic yield and specimen adequacy than EUS-FNA.In our experience,specimen processing as histology may have contributed to the overall increased diagnostic yield of EUS-FNB. | Lawrence Ku Mohammad A Shahshahan Linda A Hou Viktor E Eysselein Sofiya Reicher | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，8： | 1 |
| 13 | Stereosdective photochemical 1,3-dioxolane addition to 5-alkoxymethyl-2 (5-H) -furanone: Synthesis of bis-tetrahydrofuranyl ligand for HIV protease inhibitor UIC-94017(TMC-114) 显示文摘 | Arun K Ghosh Sofiya Leshchenko Marcus Noetzel | 2004 | J Org Chem2004，69，23： | 1 |
| 14 | Determination of free levels of phenytoin in human plasma by liquid chromatography/tandem mass spectrometry显示文摘 | Sofiya B James CO Alan PB | 2000 | J Pharm Biomed Anal2000，23，23： | 1 |
| 15 | Evaluating the risk of adverse events with interventional endoscopic retrograde cholangiopancreatography and endoscopic ultrasound procedures in cirrhotic patients显示文摘BACKGROUND Hepatic cirrhosis is associated with greater adverse event rates following surgical procedures and is thought to have a higher risk of complications with interventional procedures in general.However,these same patients often require interventional gastrointestinal procedures such as endoscopic retrograde cholangiopancreatography(ERCP)and endoscopic ultrasound(EUS).While studies examining this scenario exist,the overall body of evidence for adverse event rates associated with ERCP/EUS procedures is more limited.We sought add to the literature by examining the incidence of adverse events after ERCP/EUS procedures in our safety-net hospital population with the hypothesis that severity of cirrhosis correlates with higher adverse event rates.AIM To examine whether increasing severity of cirrhosis is associated with greater incidence of adverse events after interventional ERCP/EUS procedures.METHODS We performed a retrospective study of patients diagnosed with hepatic cirrhosis who underwent ERCP and/or EUS-guided fine needle aspirations/fine needle biopsies from January 1,2016 to March 14,2019 at our safety net hospital.We recorded Child-Pugh and Model for End-stage Liver Disease(MELD-Na)scores at time of procedure,interventions completed,and 30-day post-procedural adverse events.Statistical analyses were done to assess whether Child-Pugh class and MELD-Na score were associated with greater adverse event rates and whether advanced techniques(single-operator cholangioscopy,electrohydraulic lithotripsy/laser lithotripsy,or needle-knife techniques)were associated with higher complication rates.RESULTS 77 procedures performed on 36 patients were included.The study population consisted primarily of middle-aged Hispanic males.30-d procedure-related adverse events included gastrointestinal bleeding(7.8%),infection(6.5%),and bile leak(2%).The effect of Child-Pugh class C vs class A and B significantly predicted adverse events(β=0.55,P<0.01).MELD-Na scores also significantly predicted adverse events(β=0.037,P<0.01).Presence of advanced techniques was not associated with higher adverse events(P>0.05).When MELD-Na scores were added as predictors with the effect of Child-Pugh class C,logistic regression showed MELD-Na scores were a significant predictor of adverse events(P<0.01).The findings held after controlling for age,gender,ethnicity and repeat cases.CONCLUSION Increasing cirrhosis severity predicted adverse events while the presence of advanced techniques did not.MELD-Na score may be more useful in predicting adverse events than Child-Pugh class. | Timothy Yoo Raisa Epistola Jordan Epistola Lawrence Ku Michael W Fleischman Sofiya Reicher Viktor E Eysselein Linda A Hou | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，11： | 1 |
| 16 | Opioid Receptor Blockade Prevents Exercise- Associated Autonomic Failure in Humans显示文摘 | Sofiya Mihnan James Leu Harry Shamoon | 2012 | Diabetes2012，61，： | 1 |
| 17 | Norming Subspaces Isomorphic to l_1显示文摘Norming subspaces are studied widely in the duality theory of Banach spaces. These subspaces are applied to the Borel and Baire classifications of the inverse operators. The main result of this article asserts that the dual of a Banach space X contains a norming subspace isomorphic to 1 provided that the following two conditions are satisfied:(1) X*contains a subspace isomorphic to 1;and(2) X*contains a separable norming subspace. | Sofiya OSTROVSKA | 2015 | Acta Mathematica Sinica,English Series2015，31，5： | 0 |
| 18 | WEAK UNCORRELATEDNESS OF RANDOM VARIABLES显示文摘基于他们的时刻,为 n 随机变量的独立的新措施被学习。为以 uncorrelatedness 开始的随机的变量的独立的度的规模(为 n = 2 ) 并且在独立完成被构造。规模提供独立的措施的一个可计算的线性地订的集合。给词调音:独立;uncorrelatedness;卷绕旋转;时刻; | Sofiya Ostrovska | 2006 | Acta Mathematica Scientia2006，26，2： | 0 |
| 19 | On the diversity of fungi from soda soils显示文摘The diversity of filamentous fungi that can grow at high ambient pH values(i.e.,8–11)remains largely understudied.Here we study 100 alkalitolerant and alkaliphilic isolates from the soils around the basin of soda lakes in Asia and Africa to assess the major evolutionary lineages and morphologies pertinent to the alkaliphilic trait in filamentous fungi.The Emericellopsis lineage(Hypocreales,Hypocreomycetidae),along with Plectosphaerellaceae(Hypocreomycetidae),Pleosporaceae(Dothideomycetes),Chaetomiaceae(Sordariomycetidae)families appeared to be overrepresented with strong alkalitolerants and effective alkaliphiles.In particular,Sodiomyces species(Plectosphaerellaceae),Acrostalagmus luteoalbus(Plectosphaerellaceae),Emericellopsis alkalina(Hypocreales),Thielavia sp.(Chaetomiaceae),and Alternaria sect.Soda(Pleosporaceae)grew best at high ambient pH.The pH tolerance of Chordomyces antarcticum,Acrostalagmus luteoalbus and some other species was largely affected by the presence of extra Na+in the growth medium.Moderate alkalitolerants included Scopulariopsis members(Microascales),Fusarium,Cladosporium,and many asexual acremonium-like species from Bionectriaceae.Weak alkalitolerants were represented by sporadic isolates of Penicillium,Purpureocillium lilacinum,and Alternaria alternata species,with the growth optimum at neutral or acidic pH.Weak alkalitolerants develop loose dry chains of spores easily dispersed by air.Their presence at low frequency with the growth optimum at neutral or acidic pH leads us to treat them as transient species in the alkaline soils,as those are also ubiquitous saprobes in normal soils.Our phylogenetic analyses show that the alkaliphilic trait in filamentous fungi has evolved several times.Several lineages harboring strong alkalitolerants derived from the known marine-borne fungi(Emericellopsis,Alternaria sect.Phragmosporae),or fall within the fungi associated with halophytic grasses(Pleosporaceae).Soda soils contain a diversity of fungi that range from weak alkalitolerant to alkaliphilic,which in few cases is associated with darkly pigmented mycelium and formation of microsclerotia.The alkaliphilic trait is spread throughout the Ascomycota,and usually juxtaposes with slime-covered polyphyletic acremonium-,verticillium-,gliocladium-types of asexual morphology,hyphae aggregating in chords,and enclosed fruit bodies. | Alexey A.Grum-Grzhimaylo Marina L.Georgieva Sofiya A.Bondarenko Alfons J.M.Debets Elena N.Bilanenko | 2016 | Fungal Diversity2016，，1： | 0 |
| 20 | Symbiotic performance,shoot biomass and water-use efficiency of three groundnut(Arachis hypogaea L.)genotypes in response to phosphorus supply under field conditions in Ethiopia显示文摘Phosphorus is a key nutrient element involved in energy transfer for cellular metabolism,respiration and photosynthesis and its supply at low levels can affect legume nodulation,N2 fixation,and C assimilation.A twoyear field study was conducted in Ethiopia in 2012 and 2013 to evaluate the effects of P supply on growth,symbiotic N2 nutrition,grain yield and water-use efficiency of three groundnut genotypes.Supplying P to the genotypes significantly increased their shoot biomass,symbiotic performance,grain yield,and C accumulation.There was,however,no effect on shootδ13C values in either year.Compared to the zero-P control,supplying 40 kg$ha–1 P markedly increased shoot biomass by 77%and 66%in 2012 and 2013,respectively.In both years,groundnut grain yields were much higher at 20 and 30 kg$ha–1 P.Phosphorus supply markedly reduced shootδ15N values and increased the%Ndfa and amount of Nfixed,indicating the direct involvement of P in promoting N2 fixation in nodulated groundnut.The three genotypes differed significantly inδ15N,%Ndfa,N-fixed,grain yield,C concentration,andδ13C.The phosphorusgenotype interaction was also significant for shoot DM,N content,N-fixed and soil N uptake. | Sofiya KMUHABA Felix DDAKORA | 2020 | Frontiers of Agricultural Science and Engineering2020，7，4： | 0 |
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