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| 1 | Current update on nanoplatforms as therapeutic and diagnostic tools:A review for the materials used as nanotheranostics and imaging modalities显示文摘In the last decade,the use of nanotheranostics as emerging diagnostic and therapeutic tools for various diseases,especially cancer,is held great attention.Up to date,several approaches have been employed in order to develop smart nanotheranostics,which combine bioactive targeting on specific tissues as well as diagnostic properties.The nanotheranostics can deliver therapeutic agents by concomitantly monitor the therapy response in real-time.Consequently,the possibility of over-or under-dosing is decreased.Various non-invasive imaging techniques have been used to quantitatively monitor the drug delivery processes.Radiolabeling of nanomaterials is widely used as powerful diagnostic approach on nuclear medicine imaging.In fact,various radiolabeled nanomaterials have been designed and developed for imaging tumors and other lesions due to their efficient characteristics.Inorganic nanoparticles as gold,silver,silica based nanomaterials or organic nanoparticles as polymers,carbon based nanomaterials,liposomes have been reported asmultifunctional nanotheranostics.In this review,the imaging modalities according to their use in various diseases are summarized,providing special details for radiolabeling.In further,the most current nanotheranostics categorized via the used nanomaterials are also summed up.To conclude,this review can be beneficial for medical and pharmaceutical society as well as material scientists who work in the field of nanotheranostics since they can use this research as guide for producing newer and more efficient nanotheranostics. | Panoraia I.Siafaka Neslihan Ustundag Okur Ioannis D.Karantas Mehmet Evren Okur Evren Atlihan Gundogdu | 2021 | Asian Journal of Pharmaceutical Sciences2021,16,1: | 3 |
| 2 | One-year experience in the retinopathy of prematurity: frequency and risk factors, short-term results and follow-up显示文摘· AIM: As a result of the increase in premature births and the advances in neonatal intensive care, retinopathy of prematurity (ROP) remains one of the most important causes of childhood blindness worldwide. The main factors in the development of ROP are gestational age, birth weight and oxygen therapy. ROP continues to gain importance due to the increasing survival rates of more immature babies. · METHODS: Between January 2007 and October 2008, 203 premature infants treated at the Neonatal Intensive Care Unit (NNICU) were prospectively enrolled and the relationship between known risk factors and the occurance of ROP was studied. · RESULTS: ROP in various stages developed in 86 cases (42.4%). Statistically significant correlations were found between the development of ROP and birth weight (P < 0.0001) gestational age (P <0.0001), oxygen treatment and its duration (P <0.0001 and P =0.002), mechanical ventilation (MV) and its duration (P =0,0001 and P =0.0001), apnea(P = 0.001), intraventricular hemorrhage (IVH) (P =0.046), sepsis (P =0.0001), use of erythropoietin (EPO) (P =0.003), the number of blood transfusions and frequency (P =0.0001 and P =0.0001), surfactant application (P =0.0001), the presence of patent ductus arteriosus (PDA) (P =0.001) or bronchopu- lmonary dysplasia (BPD) (P =0.0001). No significant correlations were found between the occurance of ROP and maternal pre-eclampsia (P =0.293), multiple pregnancy (P = 0.218), or hyperbilirubinemia (P =0.494). Severity of ROP was related significantly with birth weight (P =0.0001), but no significant correlation between severity of ROP and gestational age was present. · CONCLUSION: Early description and reduction of the risk factors related with the occurance of ROP with the help of routine screening programs may warrant the prevention of visual loss, however early ophthalmic diagnosis and treatment are still mandatory to provide better visual rehabilitation. · | Sariaydin Mehmet Atlihan Fusun Calkavur Sebnem Olukman Ozgur Ercan Gulten Ozturk Arif Taylan Kaya Kilic Fatma Gokaslan Filiz Altinyaprak Derya Malatyali Rana | 2011 | International Journal of Ophthalmology(English edition)2011,4,6: | 2 |
| 3 | IgA and/or IgG subclass deficiency in children with recurrent respiratory infections and its relationship with chronic pulmonary damage显示文摘 | Ozkan H Atlihan F Genel F | | 0,,01: | 1 |
| 4 | Evaluation of adhesion molecules CD64, CDllb and CD62L in neutrophils and monocytes of peripheral blood for early diagnosis of neo- natal infection显示文摘 | Genel F Atlihan F Gulez N | 2012 | World J Pediatr2012,8,1: | 1 |
| 5 | Evaluation of adhesion molecules CD64, CDllb and CD62L in neutrophils and monocytes of peripheral blood for early diagnosis of neonatal infeetion显示文摘 | Genel F Atlihan F Gulez N | 2012 | World J Pediatr2012,8,1: | 1 |
| 6 | lgA and/or IgG subclass deficiency in children with recurrent respiratory intections and its relationship with chronic pulmonary damage 显示文摘 | Ozkan H Atlihan F Genel F | 2005 | J Investig Allergol Clin Immunol2005,15,1: | 1 |
| 7 | Evaluation of adhesion molecules CD64, CD11b and CD62L in neutrophils and monocytes of peripheral blood for early diagnosis of neonatal infec- tion显示文摘 | Genel F Atlihan F Gulez N Kazanci E Vergin C Terek D T | 2012 | World J Pediatr2012,8,: | 1 |
| 8 | Evaluation of adhesion mole- cules CD64,CDllb and CD62L in neutrophils and monocytes of peripheral blood for early diagnosis of infection显示文摘 | Genel F Atlihan F Gulez N | 2012 | World J Pedi- atr2012,8,1: | 1 |
| 9 | Proper in-deficiency in a boy with fulm inant men in go septicshock显示文摘 | Genel F Atlihan F Gulez N | 2006 | Act Paediatr2006,95,11: | 1 |
| 10 | IgA and/or IgG subclass deficiency in children with recurrent respiratory infections and its relationship with chronic pulmonary damage 显示文摘 | Ozkan H Atlihan F Genel F | 2005 | J Investig Allergol Clin Immunol2005,15,1: | 1 |
| 11 | Evaluation of adhesion molecules CD64, CDllb and CD62L in neutrophils and monocytes of peripheral blood for early diagnosis of neonatal infection 显示文摘 | Genel F Atlihan F Gulez N | 2012 | World J Pediatr2012,8,1: | 1 |
| 12 | Anatomy of the anterior sacroiliac joint with reference to lumbosacral nerves显示文摘 | Atlihan Dogan Tekdemir Ibrahim Ates Yalim | 2000 | Clinical Orthopaedics & Related Research2000,,376: | 1 |
| 13 | Anatomy of the anterior sacroil- iac joint with reference to lumbosacral nerves显示文摘 | Atlihan D Tekdemir I Ates Y | 2000 | Clin Orthop Relat Res2000,8,376: | 1 |
| 14 | Evaluation of adhesion molecules CD64, CDllb and CD62L in neutrophils and monocytes of peripheral blood for early diagnosis of neonatal infection 显示文摘 | Genel F Atlihan F Gulez N | 2012 | World J Pediatr2012,8,1: | 1 |
| 15 | IgA and/or IgG subclass deficiency in children with recurrent respiratory infections and its relationship with chronic pulmonary damage显示文摘 | Ozkan H Atlihan F Genel F | 2005 | J Investig Allergol C lin Immunol2005,15,1: | 1 |
| 16 | Evaluation of adhesion molecules CD64,CD11b and CD62L in neutrophils and monocytes of peripheral blood for early diagnosis of neonatal infection显示文摘 | Genel F Atlihan F Gulez N | | 0,,01: | 1 |
| 17 | Evaluation of adhesion molecules CD64,CDllh and CD62L in neutrophils and monocytes of peripheral blood for early diagnosis of neonatal infection显示文摘 | Genel F Atlihan F Gulez N | 2011 | World J Pediatr2011,,: | 1 |
| 18 | Monocyte HLA-DR expression aspredictor of poor outcome in neonates with late onset neonatal sep-sis显示文摘 | Genel F Atlihan F Ozsu E | 2010 | J Infect2010,60,3: | 1 |
| 19 | Arthroscopic treatment of a symptomatic hip plica显示文摘 | Atlihan D Jones DC Guanche CA | 2003 | Clin Orthop Relat Res2003,,411: | 1 |
| 20 | Evaluation of adhesion molecules CD64, CD1 l b and CD62L in neutrophils and monocytes of peripheral blood for early diagnosis of neonatal infection 显示文摘 | Genel F Atlihan F Gulez N | 2012 | World J Pediatr2012,8,1: | 1 |