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| 1 | Benefit of neoadjuvant concurrent chemoradiotherapy for locally advanced perihilar cholangiocarcinoma显示文摘AIM To clarify the role of neoadjuvant concurrent chemoradiotherapy(NACCRT) followed by surgical resection for localized or locally advanced perihilar cholangiocarcinoma(CCA).METHODS We retrospectively reviewed 57 patients who underwent surgical resection with or without NACCRT for perihilar CCA; 12 patients received NACCRT and 45 patients did not received NACCRT. Patients with locally advanced perihilar CCA requiring NACCRT were defined as follows:(1) a mass involving unilateral branches of the portal vein or hepatic artery with insufficient volume of the anticipated remnant lobe; or(2) an infiltrating mass in the main portal vein that was too long for reconstruction, identified at preoperative staging. RESULTS The median disease-free survival(DFS) durations of the neoadjuvant and non-neoadjuvant CCRT groups were26.0 and 15.1 mo, respectively(P = 0.91). The median overall survival(OS) durations of the neoadjuvant and non-neoadjuvant CCRT groups were 32.9 and 27.1 mo, respectively(P = 0.26). The NACCRT group showed a downstaging tendency compared to the non-NACCRT group as compared with the tumor stage confirmed by histological examination after surgery and the tumor stage confirmed by imaging test at the time of diagnosis(P = 0.01). CONCLUSION NACCRT does not prolong DFS and OS in localized or locally advanced perihilar CCA. However, NACCRT may allow tumor downstaging and improve tumor resectability. | Jang Han Jung Hyun Jik Lee Hee Seung Lee Jung Hyun Jo In Rae Cho Moon Jae Chung Jeong Youp Park Seung Woo Park Si Young Song Seungmin Bang | 2017 | World Journal of Gastroenterology2017，23，18： | 21 |
| 2 | Comparison of efficacy and safety between standard-dose and modified-dose FOLFIRINOX as a first-line treatment of pancreatic cancer显示文摘AIM To directly compare the efficacy and toxicity of standarddose FOLFIRINOX(sFOLFIRINOX) and modified-dose FOLFIRINOX(mFOLFIRINOX, 75% of standard-dose) for pancreatic cancer.METHODS One hundred and thirty pancreatic cancer patients who received sFOLFIRINOX(n = 88) or mFOLFIRINOX(n = 42) as their first-line chemotherapy from January 2013 to July 2017 were retrospectively reviewed. For efficacy analysis, the objective response rate(ORR),disease control rate(DCR), progression-free survival(PFS), and overall survival(OS) were evaluated and compared using Pearson's chi-square test, Kaplan-Meier plot and log-rank test. The adverse events(AEs) were evaluated, and severe(≥ grade 3) AEs rates of the two groups were compared for toxicity analysis.RESULTS The mFOLFIRINOX group included more female patients(30.7% vs 57.1%; P = 0.004) and older patients [age(median), 57 vs 63.5; P = 0.018] than the sFOLFIRINOX group. In the efficacy analysis, the ORR and DCR were not significantly different between the two groups(ORR: 39.8% vs 35.7%; P = 0.656; DCR: 80.7% vs 83.3%; P = 0.716). The median PFS and OS were also not different between the groups(PFS: 8.7 mo vs 8.1 mo, P = 0.272; OS: 13.9 mo vs 13.7 mo, P = 0.476). In the safety analysis with severe AEs, the rates of neutropenia(83.0% vs 66.7%; P = 0.044), anorexia(48.9% vs 28.6%; P = 0.029) and diarrhea(13.6% vs 0.0%; P = 0.009) were markedly lower in the mFOLFIRINOX group.CONCLUSION m FOLFIRINOX showed comparable efficacy but better safety compared to sFOLFIRINOX. If clinically necessary, initiating FOLFIRINOX with 75% of the standard-dose can alleviate toxicity concerns without compromising efficacy. | Huapyong Kang Jung Hyun Jo Hee Seung Lee Moon Jae Chung Seungmin Bang Seung Woo Park Si Young Song Jeong Youp Park | 2018 | World Journal of Gastrointestinal Oncology2018，10，11： | 6 |
| 3 | The MING proposal at SHINE:megahertz cavity enhanced X‑ray generation显示文摘The cavity-based X-ray free-electron laser(XFEL)has promise in producing fully coherent pulses with a bandwidth of a few meV and very stable intensity,whereas the currently existing self-amplified spontaneous emission(SASE)XFEL is capable of generating ultra-short pulses with chaotic spectra.In general,a cavity-based XFEL can provide a spectral brightness three orders of magnitude higher than that of the SASE mode,thereby opening a new door for cutting-edge scientific research.With the development of superconducting MHz repetition-rate XFEL facilities such as FLASH,European-XFEL,LCLS-II,and SHINE,practical cavity-based XFEL operations are becoming increasingly achievable.In this study,megahertz cavity enhanced X-ray generation(MING)is proposed based on China’s first hard XFEL facility-SHINE,which we refer to as MING@SHINE. | Nan‑Shun Huang Zi‑Peng Liu Bang‑Jie Deng Zi‑Han Zhu Shao‑Hua Li Tao Liu Zheng Qi Jia‑Wei Yan Wei Zhang Sheng‑Wang Xiang Yang‑Yang Lei Ya Zhu Yong‑Zhou He Qi‑Bing Yuan Fei Gao Rong‑Bing Deng Sen Sun Zhi‑Di Lei Zhi‑Qiang Jiang Meng‑Qi Duan Yuan Zhuan Xue‑Fang Huang Peng‑Cheng Dong Zhong‑Liang Li Shang‑Yu Si Lian Xue Si Chen Yong‑Fang Liu Ya‑Jun Tong Hai‑Xiao Deng Zhen‑Tang Zhao | 2023 | Nuclear Science and Techniques2023，34，1： | 2 |
| 4 | Differential diagnosis between gallbladder adenomas and cholesterol polyps on contrast-enhanced harmonic endoscopic ultrasonography显示文摘 | Chan Hyuk Park Moon Jae Chung Tak Geun Oh Jeong Youp Park Seungmin Bang Seung Woo Park Hyunki Kim Ho Kyoung Hwang Woo Jung Lee Si Young Song | 2013 | Surgical Endoscopy2013，，4： | 2 |
| 5 | Endoscopic Papillary Large Balloon Dilatation Alone Is Safe and Effective for the Treatment of Difficult Choledocholithiasis in Cases of Billroth II Gastrectomy: A Single Center Experience显示文摘 | Hui Won Jang Kyong Joo Lee Moon Jae Jung Joo Won Jung Jeong Youp Park Seung Woo Park Si Young Song Jae Bock Chung Seungmin Bang | 2013 | Digestive Diseases and Sciences2013，，6： | 2 |
| 6 | Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue显示文摘 | Youn BS Bang SI Kloting N | 2009 | Diabetes2009，58，3： | 1 |
| 7 | The Clinical Usefulness of 18-Fluorodeoxyglucose Positron Emission Tomography in the Differential Diagnosis, Staging, and Response Evaluation After Concurrent Chemoradiotherapy for Pancreatic Cancer显示文摘 | Seungmin Bang Hye Won Chung Seung Woo Park Jae Bock Chung Mijin Yun Jong Doo Lee Si Young Song | 2006 | Journal of Clinical Gastroenterology2006，，10： | 1 |
| 8 | Placement of a fully covered self-expandable metal stent in a young patient with chronic pancreatitis显示文摘Plastic stent insertion is a treatment option for pancreatic duct stricture with chronic pancreatitis.However, recurrent stricture is a limitation after removing the plastic stent.Self-expandable metal stents have long diameters and patency.A metal stent has become an established management option for pancreatic duct stricture caused by malignancy but its use in benign stricture is still controversial.We introduce a young patient who had chronic pancreatitis and underwent several plastic stent insertions due to recurrent pancreatic duct stricture.His symptoms improved after using a fully covered self-expandable metal covered stent and there was no recurrence found at follow-up at the outpatient department. | Kyong Joo Lee Kwang Joon Kim Dong Ho Shin Joo Won Chung Jeong Youp Park Seungmin Bang Seung Woo Park Si Young Song | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，11： | 1 |
| 9 | Radiofrequency volumetric reduction for masseteric hypertrophy 显示文摘 | Jin Park Y Woo Jo Y Bang SI | 2007 | Aesthetic Plast Surg2007，31，1： | 1 |
| 10 | Serum progranulin concen- trations may be associated with macrophage infiltration into omental adipose tissue显示文摘 | Youn BS Bang SI Kl6ting N | 2009 | Diabetes2009，58，3： | 1 |
| 11 | Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue显示文摘 | Youn BS Bang SI Kl(o)ting N | 2009 | Diabetes2009，58，3： | 1 |
| 12 | Reliability of vascular terri- tory for a circumflex scapular artery-based flap显示文摘 | Hwang JH Hwang K Bang SI | 2009 | Plast Reconstr Surg2009，123，3： | 1 |
| 13 | Phase II clinical trial of ex vivo-expanded cytokine-induced killer cells therapy in advanced pancreatic cancer显示文摘 | Moon Jae Chung Jeong Youp Park Seungmin Bang Seung Woo Park Si Young Song | 2014 | Cancer Immunology Immunotherapy2014，，9： | 1 |
| 14 | Phase II study of 5-fluorouracil and paclitaxel in patients with gemcitabine-refractory pancreatic cancer显示文摘 | Yoon Jae Kim Seungmin Bang Jeong Youp Park Seung Woo Park Jae Bock Chung Si Young Song | 2009 | Cancer Chemotherapy and Pharmacology2009，，3： | 1 |
| 15 | Active locomotion of a paddling-based capsule endoscope in an in vitro and in vivo experiment (with videos)显示文摘 | Hee Man Kim Sungwook Yang Jinseok Kim Semi Park Jae Hee Cho Jeong Youp Park Tae Song Kim Eui-Sung Yoon Si Young Song Seungmin Bang | 2010 | Gastrointestinal Endoscopy2010，，2： | 1 |
| 16 | Association of diabetes, homocysteine, and HDL with cognition and disability after stroke 显示文摘 | Newman GC Bang H Hussain SI | 2007 | Neurology2007，69，22： | 1 |
| 17 | Durable antimicrobial finish of cotton fabrics 显示文摘 | BANG E S LEE E S KIM SI | 2007 | Journal of Applied Polymer Science2007，106，： | 1 |
| 18 | CXCL5 overexpression is associated with late stage gastric cancer显示文摘 | Jeong Youp Park Kyung Hwa Park Seungmin Bang Myoung Hwan Kim Ji-Eun Lee Jingu Gang Sang Seok Koh Si Young Song | 2007 | Journal of Cancer Research and Clinical Oncology2007，，11： | 1 |
| 19 | First clinical trial of the “MiRo” capsule endoscope by using a novel transmission technology: electric-field propagation显示文摘 | Seungmin Bang Jeong Youp Park Seok Jeong Young Ho Kim Han Bo Shim Tae Song Kim Don Haeng Lee Si Young Song | 2009 | Gastrointestinal Endoscopy2009，，2： | 1 |
| 20 | Comparison of natural course, intravitreal triameinolone, and intravitreal bevaeizumab for treatment of maeular edema secondary to braneh retinal vein occlusion显示文摘 | Kwon SI Kim YW Bang YW | 2013 | J Ocular Pharmaeol Therapeutics2013，29，1： | 1 |
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