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| 1 | Identification of CD13,CD107a,and CD164 as novel basophil-activation markers and dissection of two response patterns in time kinetics of IgE-de-pendent upregulation显示文摘Using two-colour flow cytometry >200 antibodies submitted to the 8th International Workshop of Human Leukocyte Differentiation Antigens (HLDA8) have been analyzed for their reactivity with resting and activated CD203c+ basophils. Four antibodies either non-reactive or weakly reactive with resting basophils exhibited an increased reactivity with basophils activated by anti-IgE-mediated cross-linking of the high affinity IgE receptor (FcεRI). These include antibod- ies against CD164 (WS-80160, clone N6B6 and WS-80162, clone 67D2), as well as two reagents with previously unknown specificities that were identified as CD13 (WS-80274, clone A8) and CD107a (WS-80280, clone E63-880). The activation patterns followed either the “CD203c-like” or “CD63-like” activation profile. The CD203c profile is characterized by a rapid and significant upregulation (of CD13, CD164, and CD203c), reaching maximum levels after 5- 15 min of stimulation. The phosphoinositide-3-kinase (PI3K)-specific inhibitor wortmannin inhibited the upregulation of these markers whereas 12-O-tetradecanoyl-phorbol-13-acetate (TPA) induced a rapid and FcεRI-independent upregulation within 1-2 min. In the CD63 profile, maximum upregulation (of CD63 and CD107a) was detected only after 20-40 min, and upregulation by TPA reached maximum levels after 60 min. In summary, our data identify CD13, CD107a, and CD164 as novel basophil-activation antigens. Based on time kinetics of upregulation, we hypothesize that molecules of the “CD203c group” and the “CD63 group” are linked to two different mechanisms of basophil activation. | Florian HENNERSDORF Stefan FLORIAN Andreas JAKOB Katharina BAUMGRTNER Karoline SONNECK Alfred NORDHEIM Tilo BIEDERMANN Peter VALENT Hans-Jrg BüHRING | 2005 | Cell Research2005，15，5： | 9 |
| 2 | 显示文摘 | Frank Baumg?rtner lsabel Duarte John Banhart | 2000 | Advanced Engineering Materials2000，2，4： | 1 |
| 3 | Management of venous port systems in oncology:a review of current evidence显示文摘 | Vescia S Baumg?rtner AK Jacobs VR | | 0，，01： | 1 |
| 4 | Revised definition of neuropathie pain and its grading system: an open case series illustrating its use in clinical practice 显示文摘 | Geber C Baumg~irtner U Schwab R | 2009 | Am J Med2009，122，10： | 1 |
| 5 | A note ondigestibility and energy value for sheep of different grape pomace显示文摘 | Baumg'artel T Kluth H Epperlein K | 2007 | Small rumi- nant research2007，67，23： | 1 |
| 6 | Orbal lesion localization by three dimensional ultrasonography显示文摘 | BaumG Greenwood L | 1961 | Y Y State J Med1961，15，： | 1 |
| 7 | The effect of dietary phosphorus and calcium level,phytase supplementation,and ileal infusion of pectin on the chemical composition and carbohydrase activity of fecal bacteria and the level of microbial metabolites in the gastrointestinal tract of pigs显示文摘 | Metzler B Mosenthin R Baumgrtel T | 2008 | Journal of Animal Science2008，86，7： | 1 |
| 8 | Experimen- tal epididymitis due to Chlamydia trachomatis in rats显示文摘 | Jantos C Baumg/-rtner W Durchfeld B | 1992 | Infect Immun1992，60，6： | 1 |
| 9 | Ambient Air Pollution and Lipoprotein-Associated Phospholipase A^sub 2^ in Survivors of Myocardial Infarction显示文摘 | Brüske Irene Hampel Regina Baumg?rtner Zita Rückerl Regina Greven Sonja Koenig Wolfgang Peters Annette Schneider Alexandra | 2011 | Environmental Health Perspectives2011，，7： | 1 |
| 10 | Short-time plasma pre-treatment of polytetrafluoroethylene for improved adhesion显示文摘 | Baumgrtner K M Schneider J Schulz A | 2001 | Surface and Coatings Technology2001，，： | 1 |
| 11 | Industrialization of powder compact foaming process显示文摘 | Baumgrtner F Duarte I Banhart J | 2000 | Advanced Engineering Materials2000，2，4： | 1 |
| 12 | Cyclic long-term loading of a bilateral fixed-angle plate in comparison with tension band wiring with K-wires or cannulated screws in transverse patella fractures显示文摘 | Thelen S Schneppendahl J Baumg(a)rtner R | 2013 | Knee Surg Sports Traumatol Arthrosc2013，21，2： | 1 |
| 13 | Changes in bacterial populations in the ileum of pigs fed low-phosphorus diets supplemented with different sources of fermentable carbohydrates显示文摘 | Metzler B U Vahjen W T Baumg(a)rtel T | 2009 | Animal Feed Science and Technology2009，148，1： | 1 |
| 14 | Pinprick-evoked brain potentials:a novel tool to assess central sensitization of nociceptive pathways in humans显示文摘 | Iannetti GD Baumgrtner U Tracey IRD | 2013 | J Neurophysiol2013，110，： | 1 |
| 15 | STAT 3 represents a molecular switch possibly inducing astroglial instead of oligodendroglial differentiation of oligodendroglial progenitor cells in Theiler’s murine encephalomyelitis显示文摘 | Yanyong Sun Annika Lehmbecker Arno Kalkuhl Ulrich Deschl Wenhui Sun Karl Rohn Iva D. Tzvetanova Klaus‐Armin Nave Wolfgang Baumg?rtner Reiner Ulrich | 2015 | Neuropathol Appl Neurobiol2015，，3： | 1 |
| 16 | Measuring energy differences by BEC interferometry on a chip显示文摘 | Baumg rtner F Sewe Eriksson S | 2010 | Phys Rev Lett2010，105，24： | 1 |
| 17 | The Relationship between Resilience and Sustain- ability of Ecological-economic Systems显示文摘 | DERISSEN S QUAAS M F BAUMG RTNER S | 2011 | Ecological Economics2011，，： | 1 |
| 18 | Clinical course of infection and viral tissue tropism of hepatitis C virus-like nonprimate hepacivir- uses in horses显示文摘 | Pfaender S Cavalleri J Walter S Doerrbecker J Campana B Brown R Burbelo P D Postel A Hahn K Anggakusuma Riebesehl N Baumg/irtner W Be- cher P Helm M H Pietschmann T Feige K Stein- mann E | 2015 | Hepatology2015，61，2： | 1 |
| 19 | Dipole source analyses of laser evoked potentials obtained from subdural grid recordings from primary somatic sensory cortex显示文摘 | Baumgrtner U Vogel H Ohara S | 2011 | J Neurophysiol2011，106，2： | 1 |
| 20 | Potential importance of the subsoil for the P and Mg nutrition of wheat显示文摘 | H. Kuhlmann G. Baumg?rtel | 1991 | Plant and Soil1991，，2： | 1 |
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