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| 1 | Compression of enteric-coated pellets to disintegrating tablets 显示文摘 | Beckert TE Lehmann K Schmidt PC | 1996 | lnt J phann1996，143，11： | 1 |
| 2 | Compression of enteric-coated pellets to disintegrating tablets显示文摘 | Beckert TE Lehmann K Schmidt PC | 1996 | Int J Pharm1996，143，1： | 1 |
| 3 | Experiment evidence about the controversy concerning Fourier and non-Foureir heat conduction in materials with a nonhomogeneous inner structure显示文摘 | Herwig H Beckert K | 2000 | Heat Mass Transfer2000，36，5： | 1 |
| 4 | Risk factors for recurrence following complete cytoreductive surgery and HIPEC in colorectal cancer-derived peritoneal surface malignancies显示文摘 | Ingmar K?nigsrainer Philipp Horvath Florian Struller Viola Forkl Alfred K?nigsrainer Stefan Beckert | 2013 | Langenbeck’s Archives of Surgery2013，，： | 1 |
| 5 | Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms 显示文摘 | Hunt T K Aslam R S Beckert S | 2007 | Antioxid Redox Signal2007，9，8： | 1 |
| 6 | Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms显示文摘 | Hunt T K Aslam R S Beckert S | 2007 | Antioxid Redox Signal2007，9，8： | 1 |
| 7 | Electron Cooling Forces for Highly Charged Ions in the ESR 显示文摘 | Beckert K Bosch F | 1997 | Nucl Instr and Meth1997，391，1： | 1 |
| 8 | Compression of enteric-coated pellets to disintegrating tablets显示文摘 | Beckert TE Lehmann K Schmidt PC | 1996 | Int J Pharm1996，143，1： | 1 |
| 9 | Compression of enteric-coated pellets to disintegrating tablets 显示文摘 | Beckert TE Lehmann K Schmidt PC | 1996 | Int J Pharm1996，143，1： | 1 |
| 10 | A novel pH and time-basedmultiunit potential colonic drug delivery system I Development显示文摘 | Gupta V K Beckert T E Price J C | 2001 | Int J Pharm2001，213，2： | 1 |
| 11 | Compression of enteric-coated pellets to disintegrating tablets显示文摘 | Beckert TE Lehmann K Schmidt PC | 1996 | Int J Pharm1996，143，1： | 1 |
| 12 | Experiment evidence about the controversy concerning Fourier and non-Fourier heat conduction in materials with a nonhomogeneous inner structure显示文摘 | Herwing H Beckert K | 2000 | Heat Mass Transfer2000，36，5： | 1 |
| 13 | Schottky mass spectrometry at the ESR: a novel tool for precise direct mass measurements of exotic nuclei显示文摘 | Schlitt B Beckert K Bosch F | 1997 | Nucl Phys A1997，626，12： | 1 |
| 14 | Observation of a dramatic hindrance of the nuclear decay of isomeric states for fully ionized atoms显示文摘 | Litvinov Yu A Attallah F Beckert K | 2003 | Phys Lett B2003，573，： | 1 |
| 15 | Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms 显示文摘 | Hunt T K Aslam R S Beckert S | 2007 | Antioxid Redox Signal2007，9，8： | 1 |
| 16 | 查看详情显示文摘 | Sun B Kn6bel R Litvinov Y A Geissel H Meng J Beckert K Bosch F Boufin D Brandau C Chen L Cullen I J Dimopoulou C Fabian B Hausmann M Kozhuharov C Litvinov S A Mazzocco M Montes F Miizenberg G Musumarra A Nakajima S Nociforo C Nolden F Ohtsubo T Ozawa A | | 0，，： | 1 |
| 17 | Fourier versus non-Fourier heat conduction in materials with a nonhomo- geneous inner structure 显示文摘 | HERWIG H BECKERT K | 2000 | ASME Journal of Heat Transfer2000，122，2： | 1 |
| 18 | Growth hormone abolishes the negative effects of everolimus on intestinal wound healing显示文摘AIM: To investigate whether the simultaneous treatment with human growth hormone(h GH) abolishes the negative effects of everolimus on anastomotic healing.METHODS: Forty-eight male Sprague-Dawley-rats were randomized to three groups of 16 animals each(Ⅰ: vehicle; Ⅱ: everolimus 3 mg/kg po; Ⅲ: everolimus 3 mg/kg po + h GH 2.5 mg/kg sc). Animals were pretreated with h GH and/or everolimus daily for seven days. Then a standard anastomosis was created in the descending colon and treatment was continued for another seven days. The anastomosis was resected in toto and the bursting pressure was assessed as a mechanical parameter of intestinal healing. Moreover, biochemical(Hydroxyproline, PCNA, MPO, MMP-2 and MMP-9) and histological(cell density, angiogenesis, amount of granulation tissue) parameters of intestinal healing were assessed.RESULTS: Anastomotic bursting pressure was significantly reduced by everolimus and a simultaneous treatment with h GH resulted in considerably higher values(Ⅰ: 134 ± 19 mm Hg, Ⅱ: 85 ± 25 mm Hg, Ⅲ: 114 ± 25 mm Hg; P < 0.05,Ⅰvs Ⅱ; P = 0.09,Ⅰvs Ⅲ and Ⅱ vs Ⅲ) Hydroxyproline concentration was significantly increased by h GH compared to everolimus alone(Ⅰ: 14.9 ± 2.5 μg/mg, Ⅱ: 8.9 ± 3.6 μg/mg, Ⅲ: 11.9 ± 2.8 μg/mg; P < 0.05,?Ⅰvs Ⅱ/Ⅲ and Ⅱ vs Ⅲ). The number of MPO-positive cells was reduced significantly by h GHcompared to everolimus alone(Ⅰ: 10 ± 1 n/mm^2, Ⅱ: 15 ± 3 n/mm^2, Ⅲ: 9 ± 2 n/mm^2; P < 0.05,Ⅰvs Ⅱ and Ⅱ vs Ⅲ), while the number of PCNA-positive cells were increased by h GH(Ⅰ: 28 ± 3 /mm^2, Ⅱ: 12 ± 3 /mm^2, Ⅲ: 26 ± 12 /mm^2; P < 0.05,?Ⅰ?vs Ⅱ and Ⅱ vs Ⅲ). Corresponding to these biochemical findings, HEhistology revealed significantly increased amount of granulation tissue in h GH-treated animals.CONCLUSION: Inhibition of intestinal wound healing by everolimus is partially neutralized by simultaeous treatment with h GH. Both inflammation as well as collagen deposition is influenced by h GH. | Markus Alexander Küper Sebastian Trütschel Jürgen Weinreich Alfred Konigsrainer Stefan Beckert | 2016 | World Journal of Gastroenterology2016，22，17： | 0 |
| 19 | Experience after 100 patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy显示文摘AIM:To investigate perioperative patient morbidity/mortality and outcome after cytoreductive surgery(CRS) and hyperthermic intraperitoneal chemotherapy(HIPEC).METHODS:Of 150 patients 100 were treated with cytoreductive surgery and HIPEC and retrospectively analyzed.Clinical and postoperative follow-up data were evaluated.Body mass index(BMI),age and peritoneal carcinomatosis index(PCI) were chosen as selection criteria with regard to tumor-free survival and perioperative morbidity for this multimodal therapy.RESULTS:CRS with HIPEC was successfully performed in 100 out of 150 patients.Fifty patients were excluded because of intraoperative contraindication.Median PCI was 17(1-39).In 89% a radical resection(CC0/CC1) was achieved.One patient died postoperatively due to multiorgan failure.Neither PCI,age nor BMI was a risk factor for postoperative complications/outcome according to the DINDO classification.In 9% Re-CRS with HIPEC was performed during the follow-up period.CONCLUSION:Patient selection remains the most important issue.Neither PCI,age nor BMI alone should be an exclusion criterion for this multimodal therapy. | Ingmar Knigsrainer Derek Zieker Jrg Glatzle Olivia Lauk Julia Klimek Stephan Symons Bjrn Brücher Stefan Beckert Alfred Knigsrainer | 2012 | World Journal of Gastroenterology2012，18，17： | 0 |
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