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| 1 | Studies on the Antibacterial Activity of the Extract of Stachysarpheta angustifolia显示文摘Objective:To investigate the scientific bases for the traditional use of stachytarpheta angustigolia.MEthods:In vitro antibacterial activity of the aqueous and ethanol extract of the plant was investigated using the agar cup plate diffustion method.Results:The ethanol extract of the plant showed antibacterial activity against Escherichia coli,Streptococcus faecalis,Shigella dysenteriae,Staphylococcus aureus(S.aureus),Salmonella sp., pseudomonas aeruginosa and Neisseria gonorthoseae,while the water extract was active against Escherichia coli,Streptococcus faecalis,Shigella dysenteriae,Staphylococcus aureus and Pseudomonas aeruginasa.The ethanol extract exhibited higher antibacterial activity than the water extract,The minimum inhibitory comcentration(MIC) and minimum bactericidal concentration(MBC) of the ethanol extract were0.65g/L and 0.85g/L,respectively.against S.aureus.Treatment of the extract at higher temperature,60℃ increased the sensitivity of the test of ganisms to the plant extract.Phytochemical analysis indicated that the plant possesses tannins,saponins as well as phenols.Concluslon:A scientific basis that the plant possesses antibacterial activity and it could be a probable source of therapeutic agent. | Yakubu M Bello Odama L E Nandita B De | 2003 | 南京医科大学学报(自然科学版)2003,23,4: | 7 |
| 2 | Impact of minimally invasive surgery on the treatment of benign esophageal disorders显示文摘Thanks to the development of minimally invasive surgery, the last 20 years have witnessed a change in the treatment algorithm of benign esophageal disorders. Today a laparoscopic operation is the treatment of choice for esophageal achalasia and for most patients with gastroesophageal reflux disease. Because the pathogenesis of achalasia is unknown, treatment is palliative and aims to improve esophageal emptying by decreasing the functional obstruction at the level of the gastro-esophageal junction. The refinement of minimally invasive techniques accompanied by large, multiple randomized control trials with long-term outcome has allowed the laparoscopic Heller myotomy and partial fundoplication to become the treatment of choice for achalasia compared to endoscopic procedures, including endoscopic botulinum toxin injection and pneumatic dilatation. Patients with suspected gastroesophageal reflux need to undergo a thorough preoperative workup. After establishing diagnosis, treatment for gastroesophageal reflux should be individualized to patient characteristics and a decision about an operation made jointly between surgeon and patient. The indications for surgery have changed in the last twenty years. In the past, surgery was often considered for patients who did not respond well to acid reducing medications. Today, the best candidate for surgery is the patient who has excellent control of symptoms with proton pump inhibitors. The minimally invasive approach to antireflux surgery has allowed surgeons to control reflux in a safe manner, with excellent long term outcomes. Like achalasia and gastroesophageal reflux, the treatment of patients with paraesophageal hernias has also seen a major evolution. The laparoscopic approach has been shown to be safe, and durable, with good relief of symptoms over the long-term. The most significant controversy with laparoscopic paraesophageal hernia repair is the optimal crural repair. This manuscript reviews the evolution of these techniques. | Brian Bello Fernando A Herbella Marco E Allaix Marco G Patti | 2012 | World Journal of Gastroenterology2012,18,46: | 6 |
| 3 | Novel pharmacological therapy in type 2 diabetes mellitus with established cardiovascular disease: Current evidence显示文摘Cardiovascular diseases(CVDs) remain the leading cause of death in the world and in most developed countries. Patients with type 2 diabetes mellitus(T2DM)suffer from both microvascular and macrovascular diseases and therefore have higher rates of morbidity and mortality compared to those without T2DM. If current trends continue, the Center for Disease Control and Prevention estimates that 1 in 3 Americans will have T2DM by year 2050. As a consequence of the controversy surrounding rosiglitazone and the increasing prevalence of diabetes and CVDs, in 2008 the Food and Drug Administration(FDA) established new expectations for the evaluation of new antidiabetic agents, advising for pre and,in some cases, post-marketing data on major cardiovascular events. As a direct consequence, there has been a paradigm shift in new antidiabetic agents that has given birth to the recently published American Diabetes Association/European Association for the Study of Diabetes consensus statement recommending sodium-glucose cotransporter-2 inhibitors(SGLT2i) and glucagon like peptide-1 receptor agonists(GLP-1RA) in patients with T2DM and established CVD. As a result of over a decade of randomized placebo controlled cardiovascular outcome trials, the aforementioned drugs have received FDA approval for risk reduction of cardiovascular(CV) events in patients with T2DM and established CV disease.SGLT2i have been shown to have a stronger benefit in patients with congestiveheart failure and diabetic kidney disease when compared to their GLP-1RA counterparts. These benefits are not withstanding additional considerations such as cost and the multiple FDA Black Box warnings. This topic is currently an emerging research area and this mini-review paper examines the role of these two novel classes of drugs in patients with T2DM with both confirmed, and at risk for, CVD. | Leonardo Pozo Fatimah Bello Andres Suarez Francisco E Ochoa-Martinez Yamely Mendez Chelsea H Chang Salim Surani | 2019 | World Journal of Diabetes2019,10,5: | 2 |
| 4 | Plaque erosion is a major substrate for coronary thrombosis in acute myocardial infarction显示文摘 | Arbustini E dal Bello B Morbini P | 1999 | Heart1999,82,: | 1 |
| 5 | Ten-year experience with en- domyocardial biopsy in myocarditis presenting with congestive heart failure: frequency, pathologic characteristics, treatment and follow-up显示文摘 | Arbustini E Gavazzi A Dal Bello B | 1997 | G hal Cardiol1997,27,3: | 1 |
| 6 | Mierostrueture, fundamental rheology and baking characteristics of batters and breads from different gluten - free flours treated with a microbial transglutaminase 显示文摘 | Renzetti S Bello F Arendt E | 2008 | Journal of Cereal Science2008,48,1: | 1 |
| 7 | Plaque ero-sion is a major substrate for coronary thrombosis in acute myo-cardial infarction显示文摘 | ARBUSTINI E DAL BELLO B MORBINI P | 1999 | Heart1999,82,3: | 1 |
| 8 | Making decision in case-based systems using probabilities and rough sets显示文摘 | Iliana Gutiérrez Martínez Rafael E Bello Pérez | 2003 | KnowledgeBased Systems2003,16,: | 1 |
| 9 | Present day's standards in microsurgery of low-grade gliomas显示文摘 | Bello L Fava E Carrabba G | 2010 | Adv Tech Stand Neurosurg2010,35,: | 1 |
| 10 | Relaxin counteracts myocardial damage induced by ischemia-reperfusion in isolated guinea pig hearts: evidence for an involvement of nitric oxide 显示文摘 | Masini E Bani D Bello MG | 1997 | Endocrinology1997,138,11: | 1 |
| 11 | Increased echodensity of myocardial wall in the diabetic heart: an ultrasound tissue characterization study显示文摘 | Bello V D Talario L Picano E | 2009 | J Am Coll Caridol2009,41,4: | 1 |
| 12 | A population phannaco- kinetic meta- analysis of snnitinib malate ( SU11248 ) and its pri- mary metabolite (SU12662) in healthy volunteers and oncology pa- tients 显示文摘 | HOUK B E BELLO C L KANG D | 2009 | Clin Cancer Res2009,15,7: | 1 |
| 13 | The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘 | International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M | 2010 | Science2010,330,6010: | 1 |
| 14 | Cerebral correlates of visuospatial neglect: a direct cerebral stimulation study显示文摘 | Vallar G Bello L Bricolo E | 2014 | Hum Brain Mapp2014,35,4: | 1 |
| 15 | Comparison and evaluation of methods for liver segmentation from CT datasets显示文摘 | Heimann T van Ginneken B Styner MA Arzhaeva Y Aurich V Bauer C Beck A Becket C Beichel R Bekes G Bello F Binnig G Bischof H Bornik A Cashman PM Chi Y Cordova A Dawant BM Fidrich M Furst JD Furukawa D Grenacher L Hornegger J Kainmuller D Kitney RI Kobatake H Lamecker H Lange T Lee J Lennon B Li R Li S Meinzer HP Nemeth G Raicu DS Rau AM van Rikxoort EM Rousson M Rusko L Saddi KA Schmidt G Seghers D Shimizu A Slagmolen P Sorantin E Soza G Susomboon R Waite JM Wimmer A Wolf I | 2009 | IEEE Transactions on Medical Imaging2009,28,8: | 1 |
| 16 | Relaxin protects against myocardial injury caused by ischemia and reperfusion in rat heart显示文摘 | BANI D MASINI E BELLO M G | 1998 | Am J Pathol1998,152,5: | 1 |
| 17 | Semiquantitative analysis by thin-layer chromatography (TLC) of biogenic amines in dried, salted and canned fish products 显示文摘 | Valls J E Bello R A Kodaira M S | 2002 | Journal of Food Quality2002,25,2: | 1 |
| 18 | Relaxin counteracts myocardial damage induced by ischemia - reperfusion in isolated guinea pig hearts: evidence for an involvement of nitric oxide 显示文摘 | Masini E Bani D Bello MG | 1997 | Endocrinology1997,138,11: | 1 |
| 19 | Relaxin protects against myocardial injury caused by ischemia and reperfusion in rat heart显示文摘 | Bani D Masini E Bello MG | 1998 | Am J Pathol1998,152,5: | 1 |
| 20 | Detection of tissue-specific effects by methotrexate on differentiating mouse embryonic stem cells显示文摘 | Pellizzer C Bello E Adler S Hartung T Bremer S | 2004 | Birth Defects Res B Dev Reprod Toxicel2004,71,5: | 1 |