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| 1 | Efficacy,safety and immunogenicity of hexavalent rotavirus vaccine in Chinese infants显示文摘A randomized,double-blind,placebo-controlled multicenter trial was conducted in healthy Chinese infants to assess the efficacy and safety of a hexavalent live human-bovine reassortant rotavirus vaccine(HRV)against rotavirus gastroenteritis(RVGE).A total of 6400 participants aged 6-12 weeks were enrolled and randomly assigned to either HRV(n?3200)or placebo(n?3200)group.All the subjects received three oral doses of vaccine four weeks apart.The vaccine efficacy(VE)against RVGE caused by rotavirus serotypes contained in HRV was evaluated from 14 days after three doses of administration up until the end of the second rotavirus season.VE against severe RVGE,VE against RVGE hospitalization caused by serotypes contained in HRV,and VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were also investigated.All adverse events(AEs)were collected for 30 days after each dose.Serious AEs(SAEs)and intussusception cases were collected during the entire study.Our data showed that VE against RVGE caused by serotypes contained in HRV was 69.21%(95%CI:53.31-79.69).VE against severe RVGE and RVGE hospitalization caused by serotypes contained in HRV were 91.36%(95%CI:78.45-96.53)and 89.21%(95%CI:64.51-96.72)respectively.VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were 62.88%(95%CI:49.11-72.92),85.51%(95%CI:72.74-92.30)and 83.68%(95%CI:61.34-93.11).Incidences of AEs from the first dose to one month post the third dose in HRV and placebo groups were comparable.There was no significant difference in incidences of SAEs in HRV and placebo groups.This study shows that this hexavalent reassortant rotavirus vaccine is an effective,well-tolerated,and safe vaccine for Chinese infants. | Zhiwei Wu Qingliang Li Yan Liu Huakun Lv Zhaojun Mo Fangjun Li Qingchuan Yu Fei Jin Wei Chen Yong Zhang Teng Huang Xiaosong Hu Wei Xia Jiamei Gao Haisong Zhou Xuan Bai Yueyue Liu Zhenzhen Liang Zhijun Jiang Yingping Chen Jiuwei Zhang Jialiang Du Biao Yang Bo Xing Yantao Xing Ben Dong Qinghai Yang Chen Shi Tingdong Yan Bo Ruan Haiyun Shi Xingliang Fan Dongyang Feng Weigang Lv Dong Zhang Xiangchu Kong Liuyifan Zhou Dinghong Que Hong Chen Zhongbing Chen Xiang Guo Weiwei Zhou Cong Wu Qingrong Zhou Yuqing Liu Jian Qiao Ying Wang Xinguo Li Kai Duan Yuliang Zhao Gelin Xu Xiaoming Yang | 2022 | Virologica Sinica2022，37，5： | 2 |
| 2 | Gas storage in porous aromatic frameworks (PAFs)显示文摘 | Ben Teng Pei Cuiying Zhang Daliang | 2011 | Energy and Environmental Science2011，4，10： | 1 |
| 3 | Gas storage in porous aromatic frameworks (PAFs)显示文摘 | BEN Teng PEI Cuiying ZHANG Daliang | 2011 | Energy and Environmental Science2011，4，10： | 1 |
| 4 | Genome-wide scan of Graves' disease: evidence for linkage on chromosome 5q31 in Chinese Han pedigrees 显示文摘 | Teng W Ben S | 2003 | J Clin Endocrinol Metab2003，88，4： | 1 |
| 5 | Genome -wide scan of Graves' disease: evidence for linkage on chromosome 5@ 1 in Chinese Han pedigrees 显示文摘 | Jin Y Teng W Ben S | 2003 | J Clin Endncrinol Metab2003，88，4： | 1 |
| 6 | Genome-wide scan of Graves' disease: evidence for linkage on chromosome 5q31 in Chinese Han pedigrees 显示文摘 | Jin Y Teng W Ben S | 2003 | J Clin Endocrinol Metab2003，88，4： | 1 |
| 7 | Genome-wide scan of Graves'disease:evidence for linkae on chromosome 5q31 in Chinese Han pedigrees显示文摘 | Jin Y Teng W Ben S | 2003 | J Clin Endocrinol Metab2003，88，4： | 1 |
| 8 | Gas storage in porous aromatic frameworks显示文摘 | BEN Teng PEI Cuiying ZHANG Daliang | 2011 | Energy and Environmental Science2011，4，10： | 1 |
| 9 | Genome-wide scan of Graves,disease:Evidence for linkage on chromosome 5q31 in Chinese Han pedigrees显示文摘 | Jin Y Teng WP Ben ST | 2003 | J Clin Endocrinol Metab2003，88，4： | 1 |
| 10 | Genome-wide scan of Graves disease:evidence for linkage on chromosome 5q31 in Chinese Han pedigrees显示文摘 | Teng W Ben S | 2003 | J Clin Endocrinol Metab2003，88，4： | 1 |
| 11 | Gas storage in porous aromatic frameworks显示文摘 | BEN Teng PEI Cuiying ZHANG Daliang | 2011 | Energy and Environmental Science2011，4，10： | 1 |
| 12 | Genome -wide scan of Graves' disease: evidence for linkage on chromosome 5q31 in Chinese Han pedigrees显示文摘 | JIN Y TENG W BEN S | 2003 | J Clin Endocrinol Metab2003，88，4： | 1 |
| 13 | Porous Organic Frameworks-derived Porous Carbons with Outstanding Gas Adsorption Performance显示文摘 | YAN Tingting XING Guolong DAS Saikat BEN Teng QIU Shilun | 2018 | Chemical Research in Chinese Universities2018，34，3： | 0 |
| 14 | Introduction of H2SO4 and H3PO4 into Crystalline Porous Organic Salts(CPOS-1)for Outstanding Proton Conductivity显示文摘To improve the proton conduction of crystalline porous organic salts(CPOS-l),H2SO4 and H3PO4 were introduced into the channel to obtain H2SO4@CPOS-1 and H3PO4@CPOS-1.Compared to CPOS-1,the proton conductivities of H2SO4@CPOS-1 and H3PO4@CPOS-1 increased two orders of magnitude and one order of magnitude at 303 K and 100%RH,respectively.It can be attributed to the increasing concentration of the protons,which disso ciates trom the acids. | WANG Yuxia YAN Tingting BEN Teng | 2020 | Chemical Research in Chinese Universities2020，36，5： | 0 |
| 15 | Impregnated Sulfur in Carbonized Nitrogen-containing Porous Organic Frameworks as Cathode with High Rate Performance and Long Cycle Life for Lithium-sulfur Batteries显示文摘The undesirable cycling performance caused by soluble poly sulfides shuttling between anode and cathode has been considered as the main challenge that has hindered its practical applications for lithium-sulfiir(Li-S) batteries. To solve tliis issue effectively, a nitrogen-containing porous carbon, namely JUC-Z2-900,developed from a porous organic framework, namely JUC-Z2, bearing a high surface area(805 m^2/g),small pore size(0.5 mil) and nitrogen doping(2.15%, mass fraction), has been used as a host material for Li-S batteries. The micropores of JUC-Z2-900 can confine the smaller sulfur molecules S2-4, which can essentially alleviate the critical problem of poly sulfide dissolution.Furthermore, nitrogen-containing JUC-Z2-900 can promote chemical adsorption of sulfur. The above two factors can improve the electrochemical performance of Li-S batteries effectively. To compare the eftects of sulfur contents and melt-difiusion strategy in JUC-Z2-900/S composites, a series of JUC-Z2-900/S composites was synthesized and tlieir electrochemical perfbnnances were explored, indicating good rate performance and excellent cycling stability of the composites contributed by both appropriate mass percentage of sulfiir and its confinement in the micropores. | DONG Yan BEN Teng | 2019 | Chemical Research in Chinese Universities2019，35，4： | 0 |
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